914 completed, 266 unknown, 229 recruiting, 117 not yet recruiting. 1057 Not applicable, 152 Phase 2, 78 Phase 1, 59 Phase 3, 35 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of Exposure in Hyperacusis Psychoeducation - Hyperacusis | Not applicable | Not yet recruiting | University Hospital, Antwerp | 5 | 2027-12-07 | 2026-04-29 |
| First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear Implant Otic neural progenitors, cochlear implantation - Sensorineural Hearing Loss, Presbyacusis | Phase 1 / Phase 2 | Not yet recruiting | Rinri Therapeutics | 20 | 2027-09-01 | 2026-10-01 |
| Hearing Loss and Brain Health Study Over-The-Counter (OTC) hearing aid - Hearing Loss, Adult-Onset, Dementia | Not applicable | Not yet recruiting | University of Southern California | 40 | 2027-07-01 | 2026-05-08 |
| Microtable® Method for Cochlear Implantation Investigational Device Exemption (IDE) The Microtable® Stereotactic System - Hearing Loss, Cochlear | Not applicable | Not yet recruiting | Medical University of South Carolina | 12 | 2027-07-01 | 2026-06-18 |
| Cochlear Implantation and Social Outcomes Cochlear implant - Hearing Loss, Bilateral Sensorineural | Not yet recruiting | University of Southern California | 40 | 2027-07-01 | 2026-06-22 | |
| Intervention for Hearing Health Among Native Americans Talking Circle, Diabetes prevention program & delayed TC - Noise-Induced Hearing Loss | Not applicable | Not yet recruiting | University of California, San Francisco | 400 | 2027-04-01 | 2026-08-21 |
| Maximizing Quality of Life After Cancer Through Rehabilitation TIMELY REHAB - Head and Neck Cancer, Hearing Loss | Not applicable | Not yet recruiting | VA Office of Research and Development | 74 | 2027-03-01 | 2026-06-03 |
| From Early Music Audiometry to Tone Audiograms Soundfield Behavioral Audiometry - Hearing Loss, Audiometric Tests | Not yet recruiting | Guy's and St Thomas' NHS Foundation Trust | 100 | 2027-03-01 | 2026-07-24 | |
| A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) Glycerol Tributyrate - MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus) | Phase 1 / Phase 2 | Not yet recruiting | George Washington University | 24 | 2027-03-01 | 2026-10-05 |
| Auditory-Cognitive Optimization Care Program for Older Adults With Hearing Loss and Cognitive Impairment Auditory-Cognitive Optimization Care Program (A-COP), Hearing Management and Newspaper-Reading Activities - Hearing Loss, Cognitive Impairment | Not applicable | Not yet recruiting | Taipei Medical University | 76 | 2027-02-01 | 2026-10-13 |
| A Study Testing Safety and Efficacy of Transtympanic Paliroden for the Treatment of Cochlear Synaptopathy in Participants With Chronic, Constant Tinnitus paliroden (CIL001), Placebo - Tinnitus, Bilateral, Cochlear Synaptopathy | Phase 1 / Phase 2 | Not yet recruiting | Cilcare SAS | 60 | 2027-01-01 | 2026-09-17 |
| Multimodal Therapy for Somatosensory Tinnitus Multimodal physiotherapy for TMJ and Cervical spine, Combined Exercise Program (Aerobic + Resistance + Breathing), Tinnitus-Specific Psychological Support - Ear Noise, Tinnitus, Noise Induced | Not applicable | Not yet recruiting | Charles University, Czech Republic | 160 | 2027-01-01 | 2026-03-12 |
| The Hear Clear Study Signal-to-Noise Ratio Enhancement (SNR+), Signal-to-Noise Ratio Neutral (SNR-) - Hearing Loss | Not applicable | Not yet recruiting | Duke University | 125 | 2027-01-01 | 2026-09-21 |
| Advanced Neurofeedback for Tinnitus Neurofeedback - Tinnitus, Subjective | Not applicable | Not yet recruiting | University of Zurich | 24 | 2027-01-01 | 2026-09-21 |
| Efficacy of Acupuncture on Chronic Tinnitus and Its Association With Auditory Brainstem Response Measures Acupuncture - Tinnitus, Acupuncture | Not applicable | Not yet recruiting | The Third Affiliated hospital of Zhejiang Chinese Medical University | 72 | 2026-12-31 | 2026-04-13 |
| Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss Dexamethasone, Hyaluronic acid, Indocyanine green(ICG) - Hearing Loss, Sensorineural, Hearing Loss, Sudden | Phase 1 / Phase 2 | Withdrawn | Seoul National University Hospital | 2026-12-15 | 2026-05-22 | |
| 24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher Syndrome N-acetylcysteine amide, Placebo - Retinitis Pigmentosa (RP), Usher Syndrome | Phase 3 | Not yet recruiting | Nacuity Pharmaceuticals, Inc. | 80 | 2026-12-01 | 2026-07-01 |
| SPI-1005 in Adults Receiving Cochlear Implant Ebselen, Placebo - Hearing Loss, Cochlear Trauma | Phase 2 | Recruiting | Sound Pharmaceuticals, Incorporated | 40 | 2026-12-01 | 2026-06-26 |
| HEARS Maryland: Extending Capacity for Affordable, Accessible Hearing Care Through Older Adult Peer Mentorship HEARS MD Device, HEARS MD Program - Hearing Loss, Hearing Impairment | Not applicable | Not yet recruiting | Johns Hopkins University | 300 | 2026-11-30 | 2026-07-29 |
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
Showing 20 of 1763. Sign in to see all of them.
Hearing Loss (764) · Tinnitus (426) · Hearing Loss, Sensorineural (336) · Deafness (148) · Hearing Loss, Conductive (81) · Presbycusis (66) · Hearing Loss, Sudden (65) · Hearing Loss, Bilateral (54) · Hearing Loss, Unilateral (49) · Hearing Loss, Noise-Induced (45) · Hearing Loss, Mixed Conductive-Sensorineural (43) · Cognitive Dysfunction (34) · Usher Syndromes (33) · Hyperacusis (32)
Nervous System Diseases (1760) · Neurologic Manifestations (1759) · Sensation Disorders (1756) · Pathological Conditions, Signs and Symptoms (1754) · Signs and Symptoms (1752) · Otorhinolaryngologic Diseases (1744) · Ear Diseases (1741) · Hearing Loss (597) · Hearing Loss, Sensorineural (125) · Mental Disorders (100) · Eye Diseases (93) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (87) · Behavior (85) · Central Nervous System Diseases (75)
Hearing Aids (79) · Cochlear Implants (45) · Transcranial Direct Current Stimulation (22) · Cochlear Implantation (19) · Cognitive Behavioral Therapy (14) · Transcranial Magnetic Stimulation (14) · Audiometry (13) · Dexamethasone (13) · Hearing (12) · Acetylcysteine (11) · ebselen (11) · Surveys and Questionnaires (10) · Noise (9) · Acupuncture Therapy (8) · Counseling (8)
Cochlear (83) · Sonova AG (81) · Oticon Medical (43) · Washington University School of Medicine (31) · VA Office of Research and Development (25) · MED-EL Elektromedizinische Geräte GesmbH (24) · Assistance Publique - Hôpitaux de Paris (23) · US Department of Veterans Affairs (22) · University Hospital, Antwerp (21) · Eye & ENT Hospital of Fudan University (19) · Northwestern University (18) · Med-El Corporation (16) · NYU Langone Health (16) · University Hospital, Toulouse (16) · Assiut University (14)
United States (642) · France (173) · United Kingdom (99) · Germany (96) · Switzerland (74) · Belgium (72) · Canada (70) · China (68) · Australia (62) · Netherlands (49) · Turkey (Türkiye) (46) · Brazil (33) · Sweden (30) · Spain (29) · Denmark (28)
Jinyu Qian, PhD (9) · Jay F Piccirillo, MD (8) · Carl LeBel, PhD (7) · Jonathan Kil, MD (6) · Barbara Simon, AuD (5) · Bart Volckaerts, PhD (5) · Juliane Raether (5) · Ali Ismail, lecturer (4) · Pamela Souza, PhD (4) · Shan Sun (4) · Thomas B Friedman, Ph.D. (4) · Yu-Hsiang Wu, PhD (4) · Berthold Langguth (3) · Berthold Langguth, MD (3)
PMID 35724253, PMID 17030153, PMID 22633033, PMID 24975234, PMID 25133431, PMID 27592038, PMID 29330858, PMID 29655489, PMID 30300158, PMID 31830753, PMID 32483557, PMID 34417217, PMID 35386404, PMID 35998103, PMID 36907833, PMID 37287104, PMID 37318215, PMID 37552281, PMID 41059917, PMID 41085057, PMID 10459293, PMID 10547481, PMID 10590970, PMID 11074842, PMID 11283492, PMID 11587599, PMID 11893444, PMID 12238249, PMID 12467365, PMID 12467367, PMID 12697801, PMID 12697802, PMID 12809326, PMID 12851547, PMID 14518792, PMID 14576249, PMID 15064663, PMID 15189754, PMID 15341225, PMID 15474106, PMID 1555319, PMID 15715067, PMID 15903144, PMID 15978485, PMID 16244757, PMID 16244758, PMID 16244759, PMID 16353397, PMID 16504089, PMID 16640056
R01DC015997 (4), 2018 (3), 2023 (3), 2009 (2), 2025 (2), K23DC022303 (2), R01DC012289 (2), R01DC020194 (2), R01DC021980 (2), R33DC011827 (2), U01HG006487 (2), 1IK2RX003281-01A2 (1), 1KL2TR002646-01 (1), 1RC1LM010526 (1), 1RF1MH114244 (1)