69 completed, 11 unknown, 8 not yet recruiting, 8 terminated. 34 Phase 1, 30 Phase 4, 19 Phase 2, 15 Not applicable, 12 Phase 3.
Follow Verapamil: new trials by email Literature Review of Verapamil trials Research Report on Verapamil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Two Heart Medicines for Fast, Irregular Heartbeat (Atrial Fibrillation) Verapamil Hydrochloride, Metoprolol tartrate - Atrial Fibrillation (AF), Atrial Fibrillation With Rapid Ventricular Response | Phase 4 | Not yet recruiting | Muhammad Ali Javed | 120 | 2027-01-01 | 2026-08-03 |
| Verapamil In Preclinical Type 1 Diabetes Verapamil 120 Mg/24 Hours Oral Capsule, Extended Release, Placebo, blood sampling - Type 1 Diabetes | Phase 2 / Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 50 | 2027-01-01 | 2026-10-22 |
| Drug-drug Interactions Studies of VC005 Tablets in Healthy Adult Subjects VC005 and verapamil, VC005 and probenecid, VC005 and metformin - Healthy Adult Participants | Phase 1 | Not yet recruiting | Jiangsu vcare pharmaceutical technology co., LTD | 84 | 2026-09-20 | 2026-09-01 |
| Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes Verapamil oral, Placebo - Type 1 Diabetes Mellitus | Phase 2 / Phase 3 | Recruiting | Ain Shams University | 70 | 2026-08-20 | 2026-09-04 |
| Verapamil Effect in Cystic Fibrosis-related Dysglycemia Verapamil Hydrochloride - Cystic Fibrosis Related Diabetes, Cystic Fibrosis (CF) | Phase 2 | Not yet recruiting | Rhode Island Hospital | 30 | 2026-08-01 | 2026-07-09 |
| Comparing Migraine Preventive Therapies vs. Anti-CGRP Therapies for Tinnitus in Patients With Migraine (COMPACT-PM) Galcanezumab, Erenumab 70 mg, Eptinezumab - Migraine Associated Vertigo, Tinnitus | Phase 4 | Not yet recruiting | Stanford University | 120 | 2026-07-01 | 2026-06-17 |
| SMART-VERAPAF: Self-MAnagement and Random Therapy With VERApamil or Metoprolol in Paroxysmal Atrial Fibrillation Verapamil 240 mg slow-release tablet, metoprolol 100 mg slow-release tablet - Atrial Fibrillation (AF) | Phase 4 | Not yet recruiting | Martini Hospital Groningen | 436 | 2026-06-01 | 2026-03-27 |
| Characterization of the Synergistic Antibacterial Effect of Verapamil on Bacterial Isolates From Cancer Patients verapamil - Multi Drug Resistant Organisms, Antibiotic Resistance | Not yet recruiting | Assiut University | 100 | 2026-05-01 | 2026-04-08 | |
| Precision Administration of Anti-thymocyte Globulin With or Without Verapamil Anti-thymocyte globulin (ATG), verapamil extended release capsule, Placebo - Type 1 Diabetes | Phase 2 | Recruiting | University of Florida | 60 | 2025-11-12 | 2025-11-26 |
| A Phase I/II Trial to Preserve Residual Insulin Secretion in Children With Recent Onset Type 1 Diabetes by Giving Verapamil Verapamil (Part A), Placebo - Type 1 Diabetes | Phase 1 / Phase 2 | Recruiting | Johnny Ludvigsson | 36 | 2025-08-06 | 2025-09-30 |
| Management of Acute Tinnitus With Migraine Medications Nortriptyline, Topiramate, Paroxetine - Tinnitus | Phase 4 | Active not recruiting | University of California, Irvine | 100 | 2025-06-01 | 2025-10-10 |
| Comparison of Intralesional Triamcinolone Versus Verapamil for Keloid Treatment Triamcinolone Acetonide 1 ml of 40 mg/mL suspension, Verapamil Injection - Keloid Scars | Phase 4 | Not yet recruiting | Nishtar Medical University | 60 | 2025-04-01 | 2025-04-01 |
| A Study to Evaluate Effect of Verapamil and Food of Sevasemten in Healthy Volunteers sevasemten, Verapamil - Healthy Subjects | Phase 1 | Completed | Edgewise Therapeutics, Inc. | 42 | 2025-01-08 | 2025-04-08 |
| Comparison of Intralesional Triamcinolone Acetonide Treatment With Intralesional Verapamil Hydrochloride in Keloids Triamcinolone Acetonide, Verapamil Hydrochloride - Keloid | Not applicable | Completed | Muhammad Aamir Latif | 60 | 2025-01-01 | 2026-02-19 |
| Efficacy and Safety of HB-1 for Panic Disorder HB-1, Telmisartan Only Product in Oral Dose Form, Verapamil Only Product in Oral Dose Form - Panic Disorder, Mental Illness | Phase 2 | Terminated | HB BioTech, LLC | 170 | 2024-10-29 | 2026-09-24 |
| Efficacy of Adenosine as Compared to Verapamil in Paroxysmal Supraventricular Tachycardia (pSVT) Patients Adenosine, Verapamil Injection - Supraventricular Tachycardia (SVtach) | Phase 3 | Recruiting | Rashid Latif Medical College | 210 | 2024-10-28 | 2024-12-13 |
| The Role of Verapamil in Radial Artery Spasm Verapamil - Radial Artery Spasm | Phase 4 | Completed | Mersin Medicalpark Hastanesi | 150 | 2024-06-05 | 2025-10-10 |
| Effect of Verapamil Tablets on the Pharmacokinetic of HRS-1893 Tablets in Healthy Subjects HRS-1893 tablet, Verapamil tablet - Obstructive Hypertrophic Cardiomyopathy | Phase 1 | Completed | Shandong Suncadia Medicine Co., Ltd. | 14 | 2024-04-26 | 2024-06-06 |
| Effect of Verapamil as an Adjuvant to Local Anaethetics in Supraclav Block for Hand Surgery Supraclavicular Brachial Plexus Block, Bupivacaine 0.25% 20ml alone, bupivacaine 0.25% And verapamil - Hand Surgery | Phase 4 | Completed | Ain Shams University | 32 | 2024-03-01 | 2025-02-26 |
| Clinical Trial to Assess Effect of Verapamil on Systemic Exposure of EP395 and Effect of EP395 on Systemic Exposure of Midazolam and Digoxin EP395 (Part A and B), Verapamil (Part A), Midazolam (Part B) - Chronic Obstructive Pulmonary Disease Exacerbation, COPD | Phase 1 | Completed | EpiEndo Pharmaceuticals | 37 | 2023-10-23 | 2026-04-29 |
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Atrial Fibrillation (10) · Hypertension (9) · Diabetes Mellitus, Type 1 (7) · Cardiovascular Diseases (5) · Diabetes Mellitus (4) · Cluster Headache (3) · Diabetes Mellitus, Type 2 (3) · Ischemic Stroke (3) · Keloid (3) · Migraine Disorders (3) · Obesity (3) · Seizures (3) · Tinnitus (3) · Arrhythmias, Cardiac (2) · COVID-19 (2)
Abbott (6) · Ain Shams University (4) · Assiut University (4) · AstraZeneca (3) · Boehringer Ingelheim (3) · Justin Fraser (3) · Mayo Clinic (3) · Assistance Publique - Hôpitaux de Paris (2) · Bristol-Myers Squibb (2) · Cambridge University Hospitals NHS Foundation Trust (2) · Food and Drug Administration (FDA) (2) · Medical University of Silesia (2) · Pfizer (2) · Tehran University of Medical Sciences (2) · University Health Network, Toronto (2)
United States (38) · United Kingdom (8) · Egypt (6) · Canada (5) · China (5) · France (5) · Germany (4) · Australia (3) · Netherlands (3) · Pakistan (3) · Poland (3) · Sweden (3) · Italy (2) · Russia (2) · Austria (1)
Carlos Sanabria, MD (2) · Adam P Bress, PharmD, MS (1) · Ahmed R. EL-Nahas, MD (1) · Alan G. Mallinger, M.D. (1) · Alex F Herrera (1) · Alfonso Galderisi, Phd (1) · Alison Oliveto, PhD (1) · Allan Walkey, MD (1) · Anath Shalev, MD (1) · Annelize Koch, MBChB, FFPM (1) · Anthony R Godfrey, PharmD (1) · Antoinette Moran, MD (1)
PMID 17130190, PMID 18443191, PMID 19594501, PMID 21243736, PMID 21480191, PMID 21903477, PMID 22032709, PMID 22773704, PMID 22980307, PMID 23497760, PMID 23733198, PMID 24700386, PMID 24732918, PMID 25054430, PMID 25362163, PMID 25870186, PMID 26324176, PMID 26428319, PMID 27142292, PMID 28036330, PMID 28036334, PMID 28213480, PMID 28974568, PMID 29988125, PMID 30012675, PMID 30447156, PMID 30883054, PMID 31907828, PMID 33632742, PMID 33891615, PMID 35076931, PMID 36322782, PMID 36826834, PMID 36826844, PMID 38096190, PMID 38117469, PMID 38860154, PMID 39191616, PMID 39613428, PMID 40066842, PMID 40485154, PMID 40846132, PMID 41845869, PMID 42062754, PMID 42624857
2005 (2), 2025 (2), 2008 (1), 2009 (1), 2017 (1), 2018 (1), 2023 (1), R01DA010017 (1)