13 completed, 6 unknown, 5 recruiting, 3 terminated. 13 Not applicable, 8 Phase 3, 4 Phase 2, 2 Phase 1, 2 Phase 4.
Follow Hyperacusis: new trials by email Literature Review of Hyperacusis trials Research Report on Hyperacusis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of Exposure in Hyperacusis Psychoeducation - Hyperacusis | Not applicable | Not yet recruiting | University Hospital, Antwerp | 5 | 2027-12-07 | 2026-04-29 |
| Transitional Intervention for Hyperacusis in Autism Transitional Intervention for Hyperacusis in Autism - Loudness Hyperacusis, Autism Spectrum Disorder (ASD) | Not applicable | Recruiting | University of Central Florida | 40 | 2026-08-01 | 2026-09-01 |
| Prevalence of Misophonia and Hyperacusis Among Teachers Misophonia, Hyperacusis | Completed | Ondokuz Mayıs University | 529 | 2025-03-01 | 2026-10-22 | |
| Treatment of Tinnitus With Noninvasive Neuromodulation and Listening Therapy Transcranial Direct Current Stimulation (tDCS), Sham TDCS - Tinnitus, Subjective, Hyperacusis | Not applicable | Unknown | University of Arizona | 30 | 2025-01-15 | 2024-05-08 |
| Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study High Frequency Repetitive Transcranial Magnetic Stimulation (HF rTMS), Sham Repetitive Transcranial Magnetic Stimulation (sham- rTMS), Cognitive Restructuring - Misophonia, Emotion Dysregulation | Not applicable | Completed | Duke University | 59 | 2024-05-14 | 2026-07-17 |
| De Oorzaak: Citizen Science Project on the Impact of Environmental Noise Sleep study, stress-related biomarkers and microbiome composition will be assessed using saliva samples, Audiological tests - Noise Exposure, Sleep | Unknown | University Hospital, Antwerp | 120 | 2024-04-29 | 2024-06-20 | |
| A Feasibility Study of a Novel, Fully Remote Counseling and Sound Therapy Program for Hyperacusis Sound therapy using low-level background sound, Remote counseling using HAT-Online, Sound therapy using successive approximations - Hyperacusis | Not applicable | Unknown | Augustana College | 60 | 2023-12-18 | 2024-04-17 |
| Closed-loop Rehabilitation for Hyperactive Hearing Sound Therapy 1, Sound therapy 2 - Tinnitus, Hyperacusis | Not applicable | Withdrawn | Massachusetts Eye and Ear Infirmary | 2022-09-21 | 2025-12-24 | |
| Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Prevention Rimegepant - Migraine, Episodic Migraine | Phase 4 | Completed | Pfizer | 441 | 2022-03-15 | 2025-09-03 |
| Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects Rimegepant, Placebo - Migraine | Phase 3 | Recruiting | Pfizer | 640 | 2022-02-28 | 2026-10-14 |
| Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine Rimegepant (PF-07899801) - Acute Treatment of Migraine | Phase 3 | Recruiting | Pfizer | 600 | 2021-04-28 | 2026-09-24 |
| A Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine Prevention BHV-3500 (zavegepant), Placebo - Migraine | Phase 2 / Phase 3 | Terminated | Pfizer | 1753 | 2021-03-26 | 2025-03-27 |
| Randomized Study in Children and Adolescents With Migraine: Acute Treatment Rimegepant/BHV3000, Matching placebo - Pediatric Migraine | Phase 3 | Recruiting | Pfizer | 2100 | 2021-01-15 | 2026-09-24 |
| Exploratory Study on the Role of Somatic Modulation in Hyperacusis Somatic modulation - Hyperacusis | Completed | University Hospital, Antwerp | 18 | 2020-12-07 | 2022-04-05 | |
| Randomized Trial in Adult Participants With Acute Migraines Zavegepant, Placebo - Migraine | Phase 3 | Completed | Pfizer | 1978 | 2020-10-27 | 2023-04-24 |
| Validation of a Questionnaire for Allodynia in Migraine. Questionnaire - Migraine | Unknown | University Hospital, Clermont-Ferrand | 180 | 2020-10-01 | 2020-10-08 | |
| Home-based SSP on Individuals With PWS Safe and Sound Protocol - Prader-Willi Syndrome | Not applicable | Terminated | Indiana University | 10 | 2019-04-08 | 2022-03-07 |
| Acute Treatment Trial in Adult Subjects With Migraines Zavegepant, Zavegepant matching placebo, Intranasal Aptar Pharma Unit Dose System - Migraine | Phase 2 / Phase 3 | Completed | Pfizer | 2154 | 2019-03-25 | 2023-09-25 |
| Evaluation of the Elimination of Tinnitus and Hyperacusis by the ØREBLUE® Method ØREBLUE® Method - Tinnitus, Hyperacusis | Unknown | Mayfair Developments | 40 | 2019-03-22 | 2021-02-18 | |
| Biomodulator Patch for Subjective Tinnitus Steady-State Coherent Biomodulator Patch (Antinitus), Placebo Patch - Tinnitus, Hyperacusis | Not applicable | Completed | Murat Erinç | 91 | 2018-06-12 | 2026-07-30 |
Showing 20 of 32. Sign in to see all of them.
Migraine Disorders (11) · Photophobia (11) · Tinnitus (9) · Nausea (7) · Autism Spectrum Disorder (2) · Autistic Disorder (2) · Epilepsy (2) · Hearing Disorders (2) · Prader-Willi Syndrome (2) · Social Behavior (2) · misophonia (2) · 3-Methylglutaconic Aciduria, Type V (1) · Achalasia Addisonianism Alacrimia syndrome (1) · Acrodysostosis (1)
Ear Diseases (32) · Nervous System Diseases (32) · Neurologic Manifestations (32) · Otorhinolaryngologic Diseases (32) · Pathological Conditions, Signs and Symptoms (32) · Signs and Symptoms (32) · Sensation Disorders (31) · Hearing Disorders (30) · Brain Diseases (12) · Central Nervous System Diseases (12) · Eye Diseases (12) · Headache Disorders (11) · Headache Disorders, Primary (11) · Vision Disorders (11) · Signs and Symptoms, Digestive (8)
rimegepant sulfate (5) · Cognitive Behavioral Therapy (2) · Cognitive Restructuring (1) · Counseling (1) · Diclofenac (1) · Implosive Therapy (1) · Ketoprofen (1) · Polysomnography (1) · Surveys and Questionnaires (1) · Transcranial Direct Current Stimulation (1) · Transcranial Magnetic Stimulation (1) · Videotape Recording (1)
Pfizer (8) · University Hospital, Antwerp (3) · Indiana University (2) · University of Minnesota (2) · Achelios Therapeutics (1) · Augustana College (1) · Duke University (1) · Linkoeping University (1) · Massachusetts Eye and Ear Infirmary (1) · Mayfair Developments (1) · Murat Erinç (1) · Neuromonics, Inc. (1) · Ondokuz Mayıs University (1) · ProEthic Pharmaceuticals (1) · Sanford Health (1)
United States (21) · France (4) · Poland (3) · Spain (3) · Belgium (2) · Canada (2) · Japan (2) · Sweden (2) · Turkey (Türkiye) (2) · Australia (1) · China (1) · Italy (1) · Mexico (1) · United Kingdom (1)
Hubert Lim, PhD (2) · Andrada D Neacsiu, PhD (1) · Aneta Kielar, PhD (1) · Ann Perreau, PhD (1) · Crist J. Frangakis, Ph.D. (1) · Daniel B Polley, Ph.D. (1) · David A. Eddins, Ph.D. (1) · Emmanuel Cuny, MD (1) · Gerhard Andersson, Professor (1) · Handan Turan Dizdar, PhD (1) · Hans C Larsen, Reader (1) · Jacek Kolacz, PhD (1) · Kelly N. Jahn, Ph.D. (1)
PMID 25017670, PMID 36224398, PMID 36804093, PMID 41235617, PMID 41366286, PMID 42645743
R01DC004678 (1)