19 completed, 2 unknown, 1 recruiting, 1 terminated. 6 Phase 4, 4 Phase 1, 4 Phase 2, 2 Early Phase 1, 2 Not applicable.
Follow Thiamine Deficiency: new trials by email Literature Review of Thiamine Deficiency trials Research Report on Thiamine Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Type 2 Diabetes and Blood Brain Barrier Improvement Thiamine, Placebo - Type2diabetes | Early Phase 1 | Recruiting | University of California, Los Angeles | 52 | 2024-08-01 | 2026-03-13 |
| The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease Thiamine - Congenital Heart Disease, Thiamine Deficiency | Early Phase 1 | Completed | Universitas Sumatera Utara | 86 | 2024-05-01 | 2026-03-24 |
| Effect of Thiamine on Serum Glucagon And Reactive Oxygen Species (ROS) Vitamin B, Placebo - Sepsis, Thiamine Deficiency | Not applicable | Completed | Universitas Sumatera Utara | 30 | 2022-10-01 | 2022-12-23 |
| Prevalence of Thiamine Deficiency in Hospitalized Non-Alcoholic Veterans Thiamine repletion - Thiamine Deficiency, Thiamine Deficiency; Sequelae | Completed | VA Office of Research and Development | 206 | 2022-07-19 | 2026-08-12 | |
| Further Development and Assessment of Tools to Measure Risk Factors for and Treatment of Thiamine Deficiency Disorders Standard of care - Thiamine Deficiency | Completed | University of California, Davis | 42 | 2022-06-15 | 2025-04-23 | |
| The Thiamine Administration After Cardiac Surgery Trial Thiamine 500 MG, Placebo - Lactate Blood Increase, Thiamine Deficiency | Phase 4 | Completed | Sarah Saxena | 200 | 2020-11-20 | 2022-11-17 |
| Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs Thiamine Mononitrate - Heart Diseases | Phase 3 | Unknown | Mahidol University | 60 | 2019-07-01 | 2019-06-20 |
| Thiamine Responsive Disorders (TRD) Among Infants in Lao PDR Thiamine 100 MG/ML - Thiamine Deficiency | Completed | University of California, Davis | 1394 | 2019-06-17 | 2022-08-15 | |
| The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine Trimethoprim, Metformin, Vitamin B1 - Vitamin B1 Deficiency, Thiamine Deficiency | Phase 4 | Completed | University of California, San Francisco | 7 | 2019-01-28 | 2025-01-03 |
| Thiamine as a Renal Protective Agent in Septic Shock Thiamine Hydrochloride, Placebo - Sepsis, Kidney Injury | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 95 | 2018-09-04 | 2023-06-27 |
| Trial of Thiamine Supplementation in Cambodia thiamine (as thiamine hydrochloride) - Thiamine Deficiency | Not applicable | Completed | Mount Saint Vincent University | 335 | 2018-08-28 | 2021-02-24 |
| Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass Neurobion, Placebo - Thiamine Deficiency, Congenital Heart Disease | Phase 4 | Unknown | National Cardiovascular Center Harapan Kita Hospital Indonesia | 50 | 2018-07-01 | 2020-07-01 |
| Thiamine Supplementation in Heart Failure: a Pilot Randomized Controlled Crossover Trial Thiamine, Placebo - Heart Failure, Heart Failure With Reduced Ejection Fraction | Phase 1 | Completed | Hamilton Health Sciences Corporation | 24 | 2018-04-02 | 2021-08-31 |
| Systemic Inflammatory Response: Thiamine and Magnesium Status (Sir TaM Study) Blood draw - Inflammation, Magnesium Deficiency | Completed | Glasgow Royal Infirmary | 47 | 2018-01-15 | 2020-04-28 | |
| High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation Thiamine, Normal saline - Hematopoietic Stem Cell Transplantation, Delirium | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 66 | 2017-10-16 | 2021-10-19 |
| Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac Arrest Thiamine, placebo - Cardiac Arrest, Shock | Phase 2 | Terminated | Beth Israel Deaconess Medical Center | 41 | 2017-05-01 | 2025-04-10 |
| Alcohol: Thiamine and or Magnesium 1 Magnesium Sulfate, Pabrinex - Alcohol Withdrawal, Lactic Acidosis | Phase 2 / Phase 3 | Completed | Glasgow Royal Infirmary | 127 | 2016-12-16 | 2019-07-31 |
| Thiamine Supplementation in Patients With Septic Shock Thiamine, Placebos - Septic Shock, Shock, Septic | Phase 1 | Withdrawn | The Cleveland Clinic | 2016-11-05 | 2019-03-15 | |
| Thiamin Deficiency in Obese Thai Children Thiamine 1, Non-thiamine, Thiamine 2 - Obesity, Child | Phase 4 | Completed | Mahidol University | 124 | 2015-08-01 | 2018-10-02 |
| Thiamin Fortified Fish Sauce as a Means of Combating Infantile Beriberi in Rural Cambodia Thiamin fortified fish sauce (low concentration), Thiamin fortified fish sauce (higher concentration), Placebo fish sauce - Thiamin Deficiency | Phase 1 | Completed | University of British Columbia | 366 | 2014-10-01 | 2016-05-25 |
Showing 20 of 24. Sign in to see all of them.
Beriberi (9) · Acidosis, Lactic (4) · Heart Failure (4) · Delirium (2) · Heart Defects, Congenital (2) · Magnesium Deficiency (2) · Sepsis (2) · Wernicke Encephalopathy (2) · Anemia, Iron-Deficiency (1) · Breast Feeding (1) · Ductus Arteriosus, Patent (1) · Heart Arrest (1) · Heart Diseases (1) · Heart Septal Defects, Atrial (1)
Avitaminosis (24) · Deficiency Diseases (24) · Malnutrition (24) · Nutrition Disorders (24) · Nutritional and Metabolic Diseases (24) · Vitamin B Deficiency (24) · Pathological Conditions, Signs and Symptoms (9) · Cardiovascular Diseases (8) · Heart Diseases (7) · Metabolic Diseases (7) · Pathologic Processes (5) · Acid-Base Imbalance (4) · Acidosis (4) · Signs and Symptoms (4)
Thiamine (15) · Saline Solution (4) · thiamine hydrochloride (3) · Sodium Chloride (2) · Standard of Care (2) · Blood Specimen Collection (1) · Folic Acid (1) · Glucose (1) · Magnesium Sulfate (1) · Metformin (1) · Thymidine Monophosphate (1) · Trimethoprim (1) · Vitamin B Complex (1)
Beth Israel Deaconess Medical Center (2) · Glasgow Royal Infirmary (2) · Mahidol University (2) · Unity Health Toronto (2) · Universitas Sumatera Utara (2) · University of California, Davis (2) · Hamilton Health Sciences Corporation (1) · Mayo Clinic (1) · Medical University of Vienna (1) · Mount Saint Vincent University (1) · National Cardiovascular Center Harapan Kita Hospital Indonesia (1) · Sarah Saxena (1) · The Cleveland Clinic (1) · UNC Lineberger Comprehensive Cancer Center (1) · University of British Columbia (1)
United States (8) · Cambodia (3) · Canada (3) · Indonesia (3) · Laos (2) · Thailand (2) · United Kingdom (2) · Austria (1) · Belgium (1)
Narumon Densupsoontorn, MD (2) · Abdul Al-Hesayen, MD (1) · Andrew S Greenberg (1) · Andrew Yan, MD (1) · Ari Moskowitz, MD (1) · Bastian Lubis, Dr (1) · Donald Rosenstein, MD (1) · Donogh Maguire, MB BCh (1) · Elisabeth A Mates, MD PhD (1) · Eric KC Wong, MD FRCPC (1) · Eva M Marwali, MD, PhD (1) · Jinesh Mehta, MD (1) · Judy McLean, PhD (1) · Katherine M Berg, MD (1) · Kathleen M Giacomini (1)
PMID 26066773, PMID 15286537, PMID 17429582, PMID 17583412, PMID 19325467, PMID 20179283, PMID 20181242, PMID 20463176, PMID 20646908, PMID 23649098, PMID 23842591, PMID 23864540, PMID 23945419, PMID 24412011, PMID 25479113, PMID 26771781, PMID 27002274, PMID 27532780, PMID 27939124, PMID 28185643, PMID 28432843, PMID 29047411, PMID 30258648, PMID 30813144, PMID 31292183, PMID 31504093, PMID 33829271, PMID 33945982, PMID 34050237, PMID 35484175, PMID 37364280, PMID 37803889, PMID 38321529, PMID 38369233, PMID 38974350, PMID 39699595, PMID 40211576, PMID 41872295
K23HL128814 (1), R01DK108722 (1), R21AG085268 (1)