111 completed, 22 unknown, 8 recruiting, 4 not yet recruiting. 54 Not applicable, 16 Phase 4, 13 Phase 2, 10 Phase 3, 7 Phase 1.
Follow Vitamin B Deficiency: new trials by email Literature Review of Vitamin B Deficiency trials Research Report on Vitamin B Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Folic Acid Salt Study (FISFA Zambia) Fortified Iodized Salt with Folic Acid (FISFA) - Folate Deficiency, Neural Tube Defects | Not applicable | Recruiting | University of Alabama at Birmingham | 250 | 2026-04-10 | 2026-06-29 |
| Oral Versus Intravenous Vitamin B12 Replacement in Hemodialysis Patients Mecobalamin IV Injection, Mecobalamin Tablets - Vitamin B12 Deficiency, Renal Failure , Chronic | Not applicable | Completed | Jinnah Hospital | 60 | 2026-02-22 | 2026-08-24 |
| Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support Choline Chloride for Injection, Placebo - Choline Deficiency, Liver Injury | Phase 2 / Phase 3 | Recruiting | Protara Therapeutics | 129 | 2025-12-10 | 2026-08-24 |
| Effectiveness of a Modified Cost-Effective Dietary Plan in Promoting Weight Loss and Preservation of Lean Body Mass in Patients After Bariatric Surgery Low-Cost Post-Bariatric Diet, Standard High-cost Post-Bariatric Diet - Obesity, Bariatric Surgery | Not applicable | Not yet recruiting | Khyber Teaching Hospital | 122 | 2025-10-01 | 2025-08-08 |
| THE B-BABIES STUDY: An Observational Study of Group B Vitamins in Preterm Infants Vitamin B-12 Deficiency | Not yet recruiting | Norfolk and Norwich University Hospitals NHS Foundation Trust | 40 | 2025-09-01 | 2025-09-09 | |
| Oral Sucrosomial® Vitamin B12 in the Management of B12 Deficiency Among Metformin-Treated Type 2 Diabetes Patients Sucrosomial® Vitamin B12, Placebo (Oral) - Vitamin B 12 Deficiency, Type 2 Diabetes Mellitus (T2DM) | Not applicable | Completed | Liaquat University of Medical & Health Sciences | 50 | 2025-08-15 | 2025-12-10 |
| Pre- and Post-Treatment Investigation of B12 and Folic Acid (Folate) Levels in Patients Receiving Antiepileptic (Anticonvulsant) Treatment for Neuropathic Pain Neuropathic Pain, Vitamin B 12 Deficiency | Completed | Gaziosmanpasa Research and Education Hospital | 96 | 2025-06-15 | 2025-09-30 | |
| Pre- and Post-Treatment Investigation of B12 and Folic Acid (Folate) Levels in Patients Receiving Antiepileptic (Anticonvulsant) Treatment for Fibromyalgia: Retrospective Study Fibromyalgia (FM), Vitamin B 12 Deficiency | Completed | Gaziosmanpasa Research and Education Hospital | 104 | 2025-06-11 | 2026-01-26 | |
| Homocysteine and Early Diastolic Dysfunction in Newly Diagnosed Hypertension Homocysteine Measurement and Echocardiography - Hypertension (HTN), Hyperhomocysteinemia | Recruiting | Necmettin Erbakan University | 500 | 2025-06-02 | 2026-03-24 | |
| A Study to See if a Combination of Vitamins That is Injected Into a Muscle is as Good and Safe as a Vitamin That is Taken by Mouth Vitamin B12, Vitamin B6, Folic acid, Vitamin B12 (Cyanocobalamin) - Vitamin B12 Deficiency | Phase 4 | Completed | Medice Arzneimittel Pütter GmbH & Co KG | 46 | 2025-04-16 | 2026-09-04 |
| Challenges in Achieving Adequate Dietary Status of Women Assessement of nutritional status, Dermis density and thickness, Skin elasticity - Nutritional Status, Nutrient Deficiency | Enrolling by invitation | Institute of Nutrition, Slovenia (Nutris) | 300 | 2025-01-06 | 2025-03-19 | |
| Diet Quality of Pregnant Women With a Strict Plant-based Diet Versus an Omnivorous Diet Daily nutritional intake - Vitamin B 12 Deficiency, Pregnancy | Not yet recruiting | Maastricht University Medical Center | 256 | 2025-01-01 | 2024-03-13 | |
| Neurological Recovery Following NOS-SACD Observational study with no interventions - Nitrous Oxide Abuse, Subacute Combined Cord Degeneration | Recruiting | Nottingham University Hospitals NHS Trust | 100 | 2024-08-19 | 2025-07-25 | |
| Type 2 Diabetes and Blood Brain Barrier Improvement Thiamine, Placebo - Type2diabetes | Early Phase 1 | Recruiting | University of California, Los Angeles | 52 | 2024-08-01 | 2026-03-13 |
| Vitamin B12 Status and Its Impact on Chronic Haemodialysis Patient Vitamin b12 measure - End Stage Renal Disease on Dialysis, Vitamin B 12 Deficiency | Unknown | Assiut University | 60 | 2024-07-05 | 2024-06-06 | |
| Folic Acid Supplementation to Reduce Anemia in Extremely Preterm Infants Folic acid - Extreme Prematurity, Anemia of Prematurity | Not applicable | Not yet recruiting | University of Calgary | 90 | 2024-06-01 | 2024-05-09 |
| The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease Thiamine - Congenital Heart Disease, Thiamine Deficiency | Early Phase 1 | Completed | Universitas Sumatera Utara | 86 | 2024-05-01 | 2026-03-24 |
| Acceptability and Nutritional Impact of Double-fortified Salt Containing Iodine and Folic Acid Iodized salt, Experimental: Iodized salt with lower-dose folic acid fortification, Experimental: Iodized salt with higher-dose folic acid fortification - Folate Deficiency, Iodine Deficiency | Not applicable | Completed | University of California, Davis | 360 | 2024-04-25 | 2025-03-13 |
| Assessing the Efficacy of Different Carrier Systems in Oral Vitamin B12 Supplementation Vit B12 - Vitamin B 12 Deficiency | Not applicable | Completed | Liaquat University of Medical & Health Sciences | 70 | 2024-04-12 | 2024-07-18 |
| Relationship Between Vitamin D and Vitamin B12 Levels and Neuropathic Pain in Lipedema Vitamin B12 Level - Vitamin D Deficiency, B12 Deficiency Vitamin | Unknown | Fatih Sultan Mehmet Training and Research Hospital | 200 | 2024-03-01 | 2024-03-29 |
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Vitamin B 12 Deficiency (71) · Hyperhomocysteinemia (33) · Folic Acid Deficiency (32) · Thiamine Deficiency (18) · Anemia (13) · Beriberi (9) · Vitamin D Deficiency (9) · Anemia, Iron-Deficiency (7) · Cardiovascular Diseases (7) · Hypertension (7) · Diabetes Mellitus, Type 2 (6) · Iron Deficiencies (6) · Anemia, Pernicious (5) · Acidosis, Lactic (4) · Arthritis, Rheumatoid (4)
Nutrition Disorders (151) · Nutritional and Metabolic Diseases (151) · Deficiency Diseases (150) · Avitaminosis (148) · Malnutrition (148) · Metabolic Diseases (59) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (42) · Genetic Diseases, Inborn (36) · Pathological Conditions, Signs and Symptoms (36) · Malabsorption Syndromes (35) · Amino Acid Metabolism, Inborn Errors (34) · Metabolism, Inborn Errors (33) · Hematologic Diseases (26) · Hemic and Lymphatic Diseases (26)
Vitamin B 12 (21) · Folic Acid (17) · Thiamine (16) · Hydroxocobalamin (5) · Saline Solution (5) · Blood Specimen Collection (4) · 5-methyltetrahydrofolate (3) · Vitamin B Complex (3) · mecobalamin (3) · thiamine hydrochloride (3) · Enalapril (2) · Leucine (2) · Methionine (2) · Observation (2) · Pyridoxine (2)
University of California, Davis (6) · Institute of Nutrition, Slovenia (Nutris) (4) · Haukeland University Hospital (3) · Mayo Clinic (3) · University of Aarhus (3) · University of British Columbia (3) · Assiut University (2) · Beth Israel Deaconess Medical Center (2) · Cornell University (2) · Gaziosmanpasa Research and Education Hospital (2) · Glasgow Royal Infirmary (2) · Hospital Universitario Dr. Jose E. Gonzalez (2) · Hydrocephalus and Neuroscience Institute (2) · Liaquat University of Medical & Health Sciences (2) · Mahidol University (2)
United States (34) · United Kingdom (9) · Canada (7) · China (6) · Germany (6) · India (6) · Turkey (Türkiye) (6) · Denmark (5) · Indonesia (5) · Austria (4) · Mexico (4) · Norway (4) · Pakistan (4) · Slovenia (4) · Belgium (3)
Igor Pravst, PhD (2) · Jogi Pattisapu, MD (2) · Julia L Finkelstein, MPH SM ScD (2) · Narumon Densupsoontorn, MD (2) · Per Magne Ueland, M.D., Ph.D. (2) · Abdul Al-Hesayen, MD (1) · Altair J Mocelin, MD PHD (1) · Amalia A Tsiami, PhD (1) · Anastasia A Smith, DrPH (1) · Anastasia Arynchyna-Smith, MPH (1) · Andrew McGovern, MD (1) · Andrew Prentice, PhD (1)
PMID 18190464, PMID 21246600, PMID 24025626, PMID 25527663, PMID 26066773, PMID 26765812, PMID 10022413, PMID 11410823, PMID 11506296, PMID 14616423, PMID 15286537, PMID 16493517, PMID 17196442, PMID 17429582, PMID 17583412, PMID 17658015, PMID 18029478, PMID 18595990, PMID 18830787, PMID 19158217, PMID 19190070, PMID 19325467, PMID 19487104, PMID 19515736, PMID 19635145, PMID 19829124, PMID 2011158, PMID 20179283, PMID 20181242, PMID 20186576, PMID 20463176, PMID 20646908, PMID 20814760, PMID 21048060, PMID 21430249, PMID 21600388, PMID 21623649, PMID 21791335, PMID 22614770, PMID 22650964, PMID 22915298, PMID 23550594, PMID 23649098, PMID 23697526, PMID 23842591, PMID 23864540, PMID 23898205, PMID 23945419, PMID 24412011, PMID 25139582
2019 (1), K23HL128814 (1), R01DK108722 (1), R01HL045267 (1), R01HL052630 (1), R01HL054711 (1), R21AG085268 (1)