Avitaminosis: Clinical Trials

832 completed, 178 unknown, 64 recruiting, 45 terminated. 460 Not applicable, 136 Phase 2, 127 Phase 4, 109 Phase 3, 59 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	460	Completed 330, Unknown 61, Recruiting 22, Terminated 15, Not yet recruiting 12, Withdrawn 11, Active not recruiting 7, Enrolling by invitation 1, Suspended 1
Phase 2	136	Completed 89, Unknown 17, Withdrawn 10, Terminated 8, Recruiting 7, Active not recruiting 3, Not yet recruiting 1, Suspended 1
Phase 4	127	Completed 92, Unknown 20, Terminated 7, Active not recruiting 3, Recruiting 2, Withdrawn 2, Not yet recruiting 1
Phase 3	109	Completed 80, Unknown 12, Terminated 6, Withdrawn 5, Recruiting 4, Active not recruiting 2
Phase 1	59	Completed 40, Unknown 9, Terminated 4, Withdrawn 3, Active not recruiting 1, Recruiting 1, Suspended 1
Early Phase 1	24	Completed 13, Unknown 6, Recruiting 3, Terminated 2

Follow Avitaminosis: new trials by email Literature Review of Avitaminosis trials Research Report on Avitaminosis

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
The Effectiveness of a Weight-dependent Algorithm for Dosing Vitamin D. Vitamin D3, Calcium, and Vitamin C - Hypovitaminosis D	Not applicable	Not yet recruiting	Atlantic Health System	200	2027-01-01	2026-10-20
Vitamin D Status and Its Influencing Factors in Zhejiang Province: A Multicenter Cross-Sectional Study Vitamin D Deficiency		Enrolling by invitation	First Affiliated Hospital of Zhejiang University	10000	2026-10-31	2026-10-08
The OK Daily Study Combined MK-7 + vitamin D3 drops, Vitamin D3 Drops, MK-7 capsules - Infant Vitamin K Status, Vitamin K Deficiency Bleeding	Not applicable	Not yet recruiting	Norfolk and Norwich University Hospitals NHS Foundation Trust	134	2026-10-01	2026-09-04
Osteoporosis & Renal Disease: Research in Primary Health Care Services Fracture risk assessment tool (FRAX), Dual-Energy X-ray Absorptiometry (DXA) - Osteoporosis, Chronic Kidney Disease Mineral and Bone Disorder		Not yet recruiting	Universidade do Porto	622	2026-10-01	2026-09-30
Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS) Vitamin D 4000IU daily, Placebo - Polycystic Ovarian Syndrome in Adolescent Females, Vitamin D Deficiency	Not applicable	Recruiting	Yale University	60	2026-09-01	2026-08-20
Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis intra-oral 3D optical impression - Osteogenesis Imperfecta, Rare Bone Disorders	Not applicable	Not yet recruiting	University Hospital, Bordeaux	240	2026-09-01	2026-06-24
Vitamin A Supplementation and Breast Milk Vitamin A Levels in Mothers of Preterm Infants Oral multivitamin containing vitamin A - Premature, Preterm Infant Health	Not applicable	Not yet recruiting	University of Mississippi Medical Center	20	2026-08-01	2026-07-30
Vitamin D Status and Asthma Control, Pulmonary Function, and Oxidative Stress in Adults With Bronchial Asthma Bronchial Asthma, Vitamin D Deficiency		Not yet recruiting	Sinai University	134	2026-07-26	2026-07-29
Vitamin D Status and Lipid Profile in Obese Adults With Type 2 Diabetes Type 2 Diabetes Mellitus, Obesity		Not yet recruiting	Sinai University	150	2026-07-25	2026-07-27
Treatment Patterns, Biochemical Profiles and Clinical Outcomes in Adults With X-Linked Hypophosphatemia No treatment given - X-linked Hypophosphatemia (XLH)		Withdrawn	Novo Nordisk A/S		2026-07-07	2026-08-28
Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD Low-dose Colchicine at 0.5mg daily, Usual Care - Chronic Kidney Disease Mineral and Bone Disorder, Hypertension	Phase 2	Not yet recruiting	University of Texas Southwestern Medical Center	60	2026-07-01	2026-06-22
Link Between ASCorbemia Level and Osteoporosis Plasma vitamin C assessment - Osteoporosis, Vitamin C Deficiency	Not applicable	Not yet recruiting	Centre Hospitalier Universitaire de Nice	40	2026-07-01	2026-06-22
Medium Cut-Off and High-Flux Membranes on Mineral and Bone Metabolism in Hemodialysis Patients Medium Cut-Off Hemodialysis Membrane, High-Flux Hemodialysis Membrane - End Stage Kidney Disease (ESKD), Hemodialysis	Not applicable	Active not recruiting	Gazi University	30	2026-07-01	2026-09-14
The Effect of Vitamin D Supplementation on the Anti-inflammatory Response in Periodontal Diseases Non-surgical periodontal treatment, Vitamin D administration, Oral Hygiene Education and Patient Motivation - Periodontal Diseases, Gingivitis	Not applicable	Recruiting	Recep Tayyip Erdogan University Training and Research Hospital	120	2026-06-03	2026-06-10
Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections Serum 25-Hydroxyvitamin D Assessment - Acute Respiratory Infections, Critical Illness in Children		Not yet recruiting	Assiut University	63	2026-06-01	2026-05-08
The Role of Urinary RhoA, NGF, and BDNF Levels in Overactive Bladder and Vitamin D Deficiency Urotherapy - Overactive Bladder, Vitamin D Deficiency	Not applicable	Not yet recruiting	Tarik Emre Sener	52	2026-05-01	2026-04-07
Calcium Isotope Ratios to Assess Calcium Bone Balance in Dialysis Children Receiving Cinacalcet Supplementary blood samples and urines samples - Children Over 3 Undergoing Dialysis With Secondary Hyperparathyroidism		Recruiting	Hospices Civils de Lyon	20	2026-04-29	2026-05-22
Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency Vitamin D2, Calcitriol - Cholestatic Liver Disease, Chronic Liver Disease (CLD)	Phase 4	Recruiting	Chulalongkorn University	54	2026-04-28	2026-08-03
Effect of Vitamin D Supplementation on Brain Waves in Female Major Depressive Disorder Patients With Hypovitaminosis D Dietary vitamin D - Major Depressive Disorder (MDD), Hypovitaminosis D	Not applicable	Enrolling by invitation	Bangladesh Medical University	34	2026-04-25	2026-05-12
ALPCO 25(OH) Vitamin D CLIA Kit - Fresh Versus Frozen Serum and Plasma Stability Study ALPCO 25(OH) Vitamin D CLIA Kit - Vitamin D Deficiency, Vitamin D Insufficiency		Enrolling by invitation	American Laboratory Products Company	80	2026-04-18	2026-05-04

Showing 20 of 1211. Sign in to see all of them.

Narrower conditions

Vitamin D Deficiency (796)  ·  Chronic Kidney Disease-Mineral and Bone Disorder (73)  ·  Vitamin B 12 Deficiency (71)  ·  Vitamin A Deficiency (65)  ·  Obesity (57)  ·  Renal Insufficiency, Chronic (54)  ·  Familial Hypophosphatemic Rickets (49)  ·  Insulin Resistance (38)  ·  Osteoporosis (36)  ·  Rickets (36)  ·  Osteomalacia (34)  ·  Hyperhomocysteinemia (33)  ·  Folic Acid Deficiency (32)  ·  Bone Diseases, Metabolic (27)

Broader conditions

Nutritional and Metabolic Diseases (1211)  ·  Deficiency Diseases (1209)  ·  Nutrition Disorders (1208)  ·  Malnutrition (1197)  ·  Metabolic Diseases (370)  ·  Pathological Conditions, Signs and Symptoms (304)  ·  Musculoskeletal Diseases (231)  ·  Urogenital Diseases (231)  ·  Female Urogenital Diseases and Pregnancy Complications (220)  ·  Pathologic Processes (199)  ·  Bone Diseases (191)  ·  Female Urogenital Diseases (191)  ·  Calcium Metabolism Disorders (188)  ·  Bone Diseases, Metabolic (182)

Interventions

Cholecalciferol (309)  ·  Vitamin D (180)  ·  Ergocalciferols (54)  ·  Blood Specimen Collection (22)  ·  Vitamin B 12 (22)  ·  burosumab (22)  ·  Calcium (21)  ·  Calcitriol (18)  ·  Folic Acid (18)  ·  Vitamin A (17)  ·  Thiamine (16)  ·  Calcifediol (15)  ·  Calcium Carbonate (15)  ·  Ascorbic Acid (12)  ·  asfotase alfa (10)

Sponsors

University of Wisconsin, Madison (18)  ·  University of Aarhus (14)  ·  Alexion Pharmaceuticals, Inc. (13)  ·  Kyowa Kirin Co., Ltd. (11)  ·  Massachusetts General Hospital (11)  ·  Mayo Clinic (11)  ·  Medical University of Graz (11)  ·  Ain Shams University (10)  ·  Cairo University (10)  ·  Creighton University (10)  ·  Hospices Civils de Lyon (10)  ·  USDA, Western Human Nutrition Research Center (10)  ·  Assiut University (9)  ·  National Taiwan University Hospital (9)  ·  Second Affiliated Hospital of Wenzhou Medical University (9)

Countries

United States (373)  ·  United Kingdom (60)  ·  Turkey (Türkiye) (53)  ·  China (51)  ·  Canada (44)  ·  Egypt (44)  ·  France (42)  ·  Denmark (34)  ·  Germany (29)  ·  Austria (26)  ·  Italy (25)  ·  Israel (23)  ·  Mexico (22)  ·  Sweden (19)  ·  Brazil (16)

Top investigators

Mahmoud S Abu-Samak, PhD (4)  ·  Michael F Holick, PhD, MD (4)  ·  Muhammad M Hammami, MD, PhD (4)  ·  Neil Binkley, M.D. (4)  ·  Benjamin U Nwosu, MD (3)  ·  Betty J Burri, PhD (3)  ·  Charles B Stephensen, PhD (3)  ·  Joel Melnick, MD (3)  ·  Laura A Armas, MD (3)  ·  Mary S McCarthy, PhD (3)  ·  Patricia Loranca-Moreno, M.D., M.Sc. (3)  ·  Alfred Sommer, M.D. (2)  ·  Alida Melse-Boonstra, PhD (2)

Results publications

PMID 33305842, PMID 39151033, PMID 39077939, PMID 26529632, PMID 40576086, PMID 21646368, PMID 24025626, PMID 32417537, PMID 32721016, PMID 32762706, PMID 35018442, PMID 40962182, PMID 18190464, PMID 18400738, PMID 18595990, PMID 21246600, PMID 22586483, PMID 22780885, PMID 23527013, PMID 25527663, PMID 25777546, PMID 25919461, PMID 26066773, PMID 26151421, PMID 26765812, PMID 27699270, PMID 28490513, PMID 30674610, PMID 31504694, PMID 32390123, PMID 32939553, PMID 33158822, PMID 36854566, PMID 10022413, PMID 10523553, PMID 10916520, PMID 11146455, PMID 11158062, PMID 11271856, PMID 11410823, PMID 11500705, PMID 11506296, PMID 11533328, PMID 12520530, PMID 12605179, PMID 12791627, PMID 14608059, PMID 14616423, PMID 14688154, PMID 14693936

NIH funding

2018 (3), 2019 (3), 2008 (2), 2009 (2), 2014 (2), 2017 (2), K23DK073356 (2), R01DK084986 (2), 1RC1HD063562 (1), 1UL1TR001863-01 (1), 2015 (1), 2016 (1), K23AG040708 (1), K23AR050995 (1), K23DK081677 (1)