3 completed, 1 terminated. 4 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 3, Terminated 1 |
| Phase 3 | 1 | Completed 1 |
Follow Thiamine Deficiency: new trials by email Literature Review of Thiamine Deficiency trials Research Report on Thiamine Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Thiamine as a Renal Protective Agent in Septic Shock Thiamine Hydrochloride, Placebo - Sepsis, Kidney Injury | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 95 | 2018-09-04 | 2023-06-27 |
| High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation Thiamine, Normal saline - Hematopoietic Stem Cell Transplantation, Delirium | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 66 | 2017-10-16 | 2021-10-19 |
| Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac Arrest Thiamine, placebo - Cardiac Arrest, Shock | Phase 2 | Terminated | Beth Israel Deaconess Medical Center | 41 | 2017-05-01 | 2025-04-10 |
| Alcohol: Thiamine and or Magnesium 1 Magnesium Sulfate, Pabrinex - Alcohol Withdrawal, Lactic Acidosis | Phase 2 / Phase 3 | Completed | Glasgow Royal Infirmary | 127 | 2016-12-16 | 2019-07-31 |
Acidosis, Lactic (2) · Beriberi (2) · Delirium (1) · Heart Arrest (1) · Magnesium Deficiency (1) · Sepsis (1) · Shock (1) · Wernicke Encephalopathy (1)
Avitaminosis (4) · Deficiency Diseases (4) · Malnutrition (4) · Nutrition Disorders (4) · Nutritional and Metabolic Diseases (4) · Vitamin B Deficiency (4) · Pathological Conditions, Signs and Symptoms (3) · Acid-Base Imbalance (2) · Acidosis (2) · Mental Disorders (2) · Metabolic Diseases (2) · Nervous System Diseases (2) · Pathologic Processes (2) · Alcohol-Related Disorders (1)
Saline Solution (3) · Thiamine (3) · thiamine hydrochloride (2) · Magnesium Sulfate (1) · Sodium Chloride (1)
Beth Israel Deaconess Medical Center (2) · Glasgow Royal Infirmary (1) · UNC Lineberger Comprehensive Cancer Center (1)
United States (3) · United Kingdom (1)
Ari Moskowitz, MD (1) · Donald Rosenstein, MD (1) · Donogh Maguire, MB BCh (1) · Katherine M Berg, MD (1) · Zev Nakamura, MD (1)
PMID 33945982, PMID 35484175, PMID 37364280, PMID 38321529
K23HL128814 (1)