16 unknown, 2 completed, 2 not yet recruiting, 1 recruiting. 11 Phase 2, 6 Phase 3, 3 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Unknown 10, Recruiting 1 |
| Phase 3 | 6 | Unknown 5, Not yet recruiting 1 |
| Phase 4 | 3 | Completed 1, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow lobaplatin: new trials by email Literature Review of lobaplatin trials Research Report on lobaplatin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Lobaplatin and Carboplatin as Neoadjuvant Therapy in HER-2 Positive Breast Cancer lobaplatin, carboplatin, Docetaxel or albumin paclitaxel - Breast Cancer | Phase 4 | Not yet recruiting | Shandong Cancer Hospital and Institute | 468 | 2025-08-01 | 2025-07-30 |
| Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma Trilaciclib, Pirarubicin, Lobaplatin - Osteosarcoma | Phase 2 | Recruiting | Peking University People's Hospital | 50 | 2024-11-13 | 2024-12-03 |
| Ramucirumab Combined With Nab-paclitaxel, Lobaplatin, and S-1 in Neoadjuvant Transformation Therapy for Advanced Gastric Cancer nab-paclitaxel, lobaplatin, and S-1 combined with ramucirumab, nab-paclitaxel, lobaplatin, and S-1 - Advanced Gastric Cancer | Phase 4 | Unknown | Yang Jianjun, PhD | 140 | 2023-12-30 | 2024-01-23 |
| A Multi-center, Randomized, Double-blind, Phase III Clinical Trial of Leucogen Versus Placebo on Leukocyte and Platelet Whole-course Management Assisted by PFLL Chemotherapy in the Treatment of Stage IV, Recurrent or Metastatic NPC 5-fu, Lobaplatin, Placebo - Nasopharyngeal Carcinoma, Leucogen | Phase 3 | Not yet recruiting | Sun Yat-sen University | 132 | 2023-04-01 | 2023-03-22 |
| Advanced First-line Treatment of Short-term Postoperative Progression of Head and Neck Squamous Cell Carcinoma Camrelizumab, Cisplatin, Carboplatin - Head and Neck Squamous Cell Carcinoma | Phase 2 | Unknown | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 46 | 2023-03-01 | 2023-12-20 |
| Applicability of PDOX in Patients With Primary Liver Cancer: A Randomized Controlled Trial Oxaliplatin, Doxorubicin, Lobaplatin - Hepatocellular Carcinoma Resectable | Phase 3 | Unknown | Zhujiang Hospital | 90 | 2023-01-01 | 2023-03-13 |
| Applicability of 3D-HDRA in Patients With Primary Liver Cancer: A Randomized Controlled Trial Oxaliplatin, Doxorubicin, Lobaplatin - Liver, Cancer of, Primary Resectable | Phase 3 | Unknown | Zhujiang Hospital | 144 | 2022-09-01 | 2023-03-02 |
| Comparative Study of Mitomycin and Lobaplatin in Advanced Colorectal Cancer Patients With Radical Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy Mitomycin, Lobaplatin - Colorectal Cancer, Chemotherapy Effect | Phase 2 | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 201 | 2022-09-01 | 2022-02-21 |
| Comparative Study of Lobaplatin and Paclitaxel in Advanced Gastric Cancer Patients With D2 Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy Paclitaxel, Lobaplatin - Gastric Cancer, Chemotherapy Effect | Phase 2 | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 231 | 2021-09-18 | 2022-02-21 |
| Eribulin Mesylate Combined With Lobaplatin in the Treatment of Recurrent or Metastatic Triple-negative Breast Cancer Eribulin Mesylate, Lobaplatin - Triple Negative Breast Cancer | Phase 2 | Unknown | Chinese Academy of Medical Sciences | 40 | 2020-06-01 | 2022-09-19 |
| A Study of Lobaplatin/Etoposide With or Without Anlotinib Maintenance Therapy in Patients With ES-SCLC Anlotinib Hydrochloride, Lobaplatin, Etoposide - Small Cell Lung Carcinoma | Phase 2 | Unknown | The First Affiliated Hospital of Guangzhou Medical University | 60 | 2019-03-01 | 2019-11-29 |
| Irinotecan Plus Lobaplatin Versus Irinotecan in the Second-line Treatment of Small Cell Lung Cancer irinotecan plus lobaplatin, irinotecan - Small-cell Lung Cancer | Phase 2 | Unknown | ShengFa Su | 72 | 2018-06-01 | 2020-02-05 |
| Etoposide Plus Lobaplatin Versus Etoposide Plus Cisplatin for Patients With Limited Small-cell Lung Cancer etoposide plus lobaplatin, etoposide plus cisplatin - Small-cell Lung Cancer | Phase 2 | Unknown | Guizhou Medical University | 118 | 2018-06-01 | 2020-02-05 |
| Lobaplation or Cisplatin in Adjuvant Chemotherapy for Esophageal Carcinoma Lobaplatin, Cisplatin - Esophageal Cancer | Phase 4 | Completed | Henan Cancer Hospital | 733 | 2018-01-31 | 2020-08-28 |
| Clinical Analysis of HIPEC for T4 Colorectal Cancer After Surgery Surgery and HIPEC with Lobaplatin, Surgery without HIPEC - Colorectal Neoplasms | Phase 3 | Unknown | Sixth Affiliated Hospital, Sun Yat-sen University | 300 | 2017-08-01 | 2017-07-18 |
| A Clinical Trial of Chemotherapy With Lobaplatin and 5-FU in Recurrent Local or Distant Advanced NPC. Lobaplatin - Recurrent Nasopharyngeal Carcinoma | Phase 2 | Unknown | Sun Yat-sen University | 60 | 2017-07-01 | 2017-07-06 |
| Docetaxel and Loplatin Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced SCCHN Lobaplatin, Cisplatin - Locally Advanced Head and Neck Squamous Cell Carcinoma | Phase 2 | Unknown | Guiyang Medical University | 144 | 2016-08-19 | 2017-04-17 |
| Dose Escalation of Lobaplatin Concurrent With IMRT for the Treatment of NPC: A Phase I Clinical Trial Lobaplatin, linear accelerator - Acute Toxic Effects, Tumor Responses | Phase 1 | Completed | Fifth Affiliated Hospital, Sun Yat-Sen University | 17 | 2016-06-22 | 2018-04-10 |
| Combine TACE and RFA Versus TACE Alone for HCC With PVTT TACE, RFA, pirarubicin,mitomycin and lobaplatin - Hepatocellular Carcinoma | Phase 3 | Unknown | Ming Zhao | 240 | 2014-10-01 | 2016-04-14 |
| Effectiveness and Toxicity of Gemcitabine/Lobaplatin Versus Gemcitabine/Cisplatin as Second-line Treatment in Metastatic Breast Cancer lobaplatin, cisplatin - Breast Cancer | Phase 2 | Unknown | Harbin Medical University | 80 | 2011-11-01 | 2012-01-24 |
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Small Cell Lung Carcinoma (3) · Breast Neoplasms (2) · Colorectal Neoplasms (2) · Esophageal Neoplasms (2) · Nasopharyngeal Carcinoma (2) · Neoplasm Metastasis (2) · Carcinoma, Hepatocellular (1) · Head and Neck Neoplasms (1) · Osteosarcoma (1) · Peritoneal Neoplasms (1) · Recurrence (1) · Squamous Cell Carcinoma of Head and Neck (1) · Stomach Neoplasms (1) · Triple Negative Breast Neoplasms (1)
Sun Yat-sen University (2) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (2) · Zhujiang Hospital (2) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Chinese Academy of Medical Sciences (1) · Fifth Affiliated Hospital, Sun Yat-Sen University (1) · Guiyang Medical University (1) · Guizhou Medical University (1) · Harbin Medical University (1) · Henan Cancer Hospital (1) · Ming Zhao (1) · Peking University People's Hospital (1) · Shandong Cancer Hospital and Institute (1) · ShengFa Su (1) · Sixth Affiliated Hospital, Sun Yat-sen University (1)
China (19)
Kaixiong Tao, Professor (2) · ShengFa Su, PhD,MD (2) · Feng Jin, Bachelor (1) · Jiexia Zhang (1) · Jingbo Wang (1) · Lin Guan (1) · MeiJin Huang, MD (1) · Ming Zhao, doctor (1) · Mingxin Pan, Prof (1) · Mingxin Pan, Prof. (1) · Peng Yuan, doctor (1) · Qingyuan Zhang, MD (1) · Siyang Wang, bachelor (1) · Xinmei Kang, MD (1) · Yin Li, Dr. (1)
PMID 32306237, PMID 10091726, PMID 11813623, PMID 22287157, PMID 22831982, PMID 25680955, PMID 29966863, PMID 34589419, PMID 36727741, PMID 37985501, PMID 38660276, PMID 8156509