7 completed, 2 not yet recruiting, 2 recruiting, 2 terminated. 15 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Completed 7, Not yet recruiting 2, Recruiting 2, Terminated 2, Enrolling by invitation 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 2, Terminated 1, Withdrawn 1 |
Follow Suicidal Ideation: new trials by email Literature Review of Suicidal Ideation trials Research Report on Suicidal Ideation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ADEPT Psilocybin-Assisted Therapy With DBT for Borderline Personality Disorder Psilocybin, Psilocybin-Assisted Therapy With Dialectical Behavior Therapy - Borderline Personality Disorder, Borderline Personality Pathology | Phase 1 | Not yet recruiting | University of Minnesota | 18 | 2026-12-01 | 2026-09-22 |
| Improving Sleep in a Psychiatric Hospital Scented Oil, Ear Plugs, Eye Mask - Sleep Disorder, Mental Health Issue | Phase 1 | Not yet recruiting | The University of Texas Health Science Center, Houston | 40 | 2025-06-01 | 2025-06-08 |
| Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury intermittent theta burst stimulation, placebo intermittent theta burst stimulation - Mild Traumatic Brain Injury, Suicidal Ideation | Phase 1 | Recruiting | VA Office of Research and Development | 55 | 2024-05-20 | 2026-04-14 |
| Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department Ketamine - Suicide, Suicidal Ideation | Phase 1 | Recruiting | Lindsay Maguire, MD | 50 | 2024-05-01 | 2026-04-15 |
| Ketamine Infusion for Rapid Reduction of Suicidality in Pediatrics Ketamine Injectable Solution, Midazolam Injectable Solution, Normal Saline 0.9% Injectable Solution - Suicidal Ideation | Phase 1 / Phase 2 | Terminated | University of British Columbia | 15 | 2022-06-01 | 2024-12-18 |
| Nitrous Oxide- Suicidal Ideation Nitrous Oxide, Placebo gas - Major Depressive Disorder, Depression | Phase 1 | Enrolling by invitation | Washington University School of Medicine | 50 | 2018-10-30 | 2025-12-22 |
| Electrophysiological Biomarkers of AV-101 Placebo, AV-101 720 mg, AV-101 1440 mg - Healthy | Phase 1 / Phase 2 | Completed | Marijn Lijffijt, PhD | 18 | 2018-09-01 | 2022-02-17 |
| The Better Resiliency Among Veterans With Omega-3's (BRAVO) Study Study Juice, Placebo Juice - Suicide | Phase 1 | Terminated | Medical University of South Carolina | 125 | 2014-03-01 | 2018-06-12 |
| Brief Intervention for Suicide Risk Reduction in High Risk Adolescents As Safe As Possible, Brite, Treatment as Usual - Adolescent Behavior | Phase 1 | Completed | University of Pittsburgh | 68 | 2014-02-01 | 2018-12-20 |
| Ketamine for Suicidality in Bipolar Depression Ketamine, Midazolam - Bipolar Disorder, Major Depressive Episode | Phase 1 / Phase 2 | Completed | New York State Psychiatric Institute | 16 | 2013-09-01 | 2020-03-11 |
| Intensive Outpatient Services for Teens Intensive Outpatient CBT, Standard Care - Depression, Suicide | Phase 1 | Completed | Brown University | 140 | 2012-09-01 | 2018-01-23 |
| Safety Study of the Effect of Scelectium Tortuosum (as Zembrin®)in Aged Normals Scelectium Tortuosum - Adverse Mental/Physical Effects of Low Dose S. Tortuosum. | Phase 1 | Completed | Woodbury, Michel, M.D. | 20 | 2011-06-01 | 2013-03-06 |
| Improving Care Provided to Patients Treated in a Level 1 Trauma Center Post-suicide Attempt Brief Intervention for Suicidality - Suicidal Ideas | Phase 1 | Completed | University of Washington | 40 | 2011-05-01 | 2015-03-10 |
| Primary Care iSBIRT to Reduce Serious Teen Health Risks iSBIRT, iSBIRT/TE - Substance-related Disorders, Depression | Phase 1 / Phase 2 | Withdrawn | Boston Children's Hospital | 2009-09-01 | 2016-10-07 | |
| Relapse Prevention for Suicidal Dually Diagnosed Youths CBT-RP (relapse prevention) + Enhanced TAU, Enhanced TAU Alone - Suicide, Attempted, Suicide, Ideation | Phase 1 | Completed | Duke University | 13 | 2005-07-01 | 2014-07-10 |
Depression (8) · Suicide (8) · Substance-Related Disorders (3) · Suicide, Attempted (3) · Adolescent Behavior (1) · Behavior (1) · Bipolar Disorder (1) · Borderline Personality Disorder (1) · Brain Concussion (1) · Brain Diseases (1) · Brain Injuries (1) · Brain Injuries, Traumatic (1) · Craniocerebral Trauma (1) · Depressive Disorder, Major (1)
Behavioral Symptoms (15) · Behavior (14) · Self-Injurious Behavior (14) · Mental Disorders (7) · Suicide (7) · Chemically-Induced Disorders (3) · Nervous System Diseases (2) · Bipolar and Related Disorders (1) · Central Nervous System Diseases (1) · Depressive Disorder (1) · Head Injuries, Closed (1) · Mood Disorders (1) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Personality Disorders (1)
Ketamine (2) · Therapeutics (2) · Crisis Intervention (1) · Dialectical Behavior Therapy (1) · Ear Protective Devices (1) · Midazolam (1) · Nitrous Oxide (1) · Odorants (1) · Psilocybin (1) · Saline Solution (1) · Secondary Prevention (1) · Standard of Care (1) · cellu-brite (1)
Boston Children's Hospital (1) · Brown University (1) · Duke University (1) · Lindsay Maguire, MD (1) · Marijn Lijffijt, PhD (1) · Medical University of South Carolina (1) · New York State Psychiatric Institute (1) · The University of Texas Health Science Center, Houston (1) · University of British Columbia (1) · University of Minnesota (1) · University of Pittsburgh (1) · University of Washington (1) · VA Office of Research and Development (1) · Washington University School of Medicine (1) · Woodbury, Michel, M.D. (1)
United States (13) · Canada (1) · Puerto Rico (1)
Alexandra L Aaronson, MD (1) · Anthony Spirito, PhD (1) · Bernadette Marriott, PhD (1) · Charles R Conway, MD (1) · David B Goldston, Ph.D. (1) · David Brent, MD (1) · Devin H Hanson, PhD, LP (1) · John R Knight, MD (1) · Joseph R Hibbeln, MD (1) · Marijn Lijffijt, PhD (1) · Michael F Grunebaum, M.D. (1) · Michel A Woodbury, MD (1) · Michelle Patriquin, PhD, ABPP (1) · Quynh Doan, PhD MHSc MD (1) · Simon Chiu, MD (1)
PMID 33884617, PMID 25389443, PMID 26977137, PMID 30021457, PMID 31328281, PMID 32368793, PMID 33318635, PMID 33677832, PMID 33825765, PMID 39671573, PMID 42234079
R01MH097703 (1), R34MH067904 (1)