24 completed, 7 recruiting, 5 unknown, 3 not yet recruiting. 18 Not applicable, 6 Phase 4, 2 Phase 1, 1 Phase 2, 1 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Validation of SMARTDIAGO for Remote Functional Assessment of Musculoskeletal Conditions SMARTDIAGO Remote Functional Assessment - Knee Osteoarthristis, Hip Osteoarthritis | Not yet recruiting | University of Chile | 350 | 2026-11-02 | 2026-10-19 | |
| Lumbar Paravertebral Block vs Erector Spinae Plane Block in Elderly Patients Undergoing Lumbar Spine Surgery Ropivacaine 0.2% Injectable Solution - Spine Disease | Not applicable | Not yet recruiting | Poznan University of Medical Sciences | 120 | 2026-06-01 | 2026-05-26 |
| Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery Auricular vagus nerve stimulation, Sham Auricular Vagus nerve Stimulation - Spinal Fusion, Hyperglycemia | Not applicable | Recruiting | Alexander T. Yahanda | 50 | 2025-10-08 | 2026-08-18 |
| Comparison of Perineural Dexamethasone Versus Dexmedetomidine as Adjuvants to Erector Spinae Plane Block in Lumbar Spine Surgery: A Randomized, Double-blind, Controlled Trial 0.9%NaCl, Dexamethasone 4mg, Dexmedetomidine - Spine Disease, Spinal Diseases | Phase 4 | Recruiting | Poznan University of Medical Sciences | 150 | 2025-09-01 | 2025-09-18 |
| Wearable Flexible Sensors for Spinal Motion Monitoring Spine Disease | Not yet recruiting | Peking University Third Hospital | 20 | 2025-06-01 | 2025-05-16 | |
| Progressive Advancements in Neurosurgery, Data and Analysis Database Self reported questionnaires - Spine Disease, Central Nervous System Diseases | Active not recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 7500 | 2025-01-15 | 2025-02-19 | |
| LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF) LDGraft, Allograft Bone - Degenerative Disc Disease, Lumbar Disc Disease | Phase 1 / Phase 2 | Recruiting | Locate Bio Pty Ltd | 40 | 2024-11-12 | 2026-08-26 |
| Erector Spinae Plane Block for Cervical Spine Surgery 0.9%sodium chloride, 0.2% ropivacaine - Spine Fusion, Spine Disease | Phase 4 | Completed | Poznan University of Medical Sciences | 60 | 2024-07-15 | 2026-02-02 |
| Active Informed Consent: a New Solution to Improve and Objectively Test the Patient Understanding of Complex Surgical Procedures Proposals active informed consent - Spine Disease, Urologic Diseases | Not applicable | Completed | Istituto Ortopedico Rizzoli | 300 | 2024-06-19 | 2026-10-09 |
| Prevalence of Diabetes in Patients Who Are Candidates for Spine Surgery Spine Disease | Recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 500 | 2024-03-28 | 2025-06-12 | |
| Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery 0.9% Sodium Chloride Injection, Dexamethasone 4 Mg/mL Injectable Solution, Dexmedetomidine injection - Spinal Fusion, Spine Disease | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2024-03-01 | 2026-05-11 |
| Sleep Apnea in Paralympic Ontario-Resident aThletes With Spinal Cord Injury (SPORTS) Study CPAP Therapy - Sleep Apnea, Breathing Disorder During Sleeping | Not applicable | Unknown | University Health Network, Toronto | 15 | 2024-02-20 | 2024-03-26 |
| MRI Analysis and Degenerative Spine MRI advanced techniques - Spine Disease | Unknown | Universidade Nova de Lisboa | 200 | 2024-01-01 | 2024-01-30 | |
| CEUS For Intraoperative Spinal Cord Injury Definity Perflutren Lipid Microsphere Ultrasound Contrast - Spine Disease, Spinal Stenosis | Not applicable | Completed | Medical University of South Carolina | 20 | 2023-12-01 | 2026-10-15 |
| The Effect of Telephone Education on Fear of Movement and Quality of Life in Patients With Lumbar Disc Herniation Surgery. post-discharge rehabilitation training - Spine Disease, Spinal Deformity | Not applicable | Unknown | Çanakkale Onsekiz Mart University | 80 | 2023-12-01 | 2024-01-05 |
| Investigation of the Efficacy of Treatments With Backup Device in Spine Pathologies electrotherapy, Backup therapy - Spine Disease, Back Pain | Not applicable | Completed | Uskudar University | 30 | 2023-09-01 | 2025-05-02 |
| Effect of an Interdisciplinary Spine Rehabilitation Program Rehabilitation program (Revita) - Low Back Pain, Spine Disease | Recruiting | KU Leuven | 90 | 2023-08-22 | 2025-09-23 | |
| Gait Spine Functional Evaluation Protocol Spine Kinematic Assessment with Optoelectronic system - Spine Disease, Gait | Not applicable | Active not recruiting | IRCCS Eugenio Medea | 20 | 2023-05-18 | 2026-04-14 |
| Iterative Endotracheal Tube Cuff Pressure Monitoring Spine Disease | Unknown | University Hospital, Strasbourg, France | 100 | 2023-03-22 | 2023-06-15 | |
| Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI (OPTIMISE SCI Trial) Continuous positive airway pressure (CPAP) therapy - Spinal Cord Injuries, Spine Disease | Not applicable | Recruiting | University Health Network, Toronto | 66 | 2022-08-15 | 2024-12-11 |
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Spinal Diseases (41) · Pain, Postoperative (6) · Spinal Cord Injuries (4) · Spinal Stenosis (3) · Back Pain (2) · Central Nervous System Diseases (2) · Low Back Pain (2) · Nervous System Diseases (2) · Sleep Apnea Syndromes (2) · Agnosia (1) · Chronic Pain (1) · Diabetes Mellitus (1) · Emergence Delirium (1) · Hyperglycemia (1) · Inflammation (1)
Bone Diseases (41) · Musculoskeletal Diseases (40) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (11) · Neurologic Manifestations (10) · Pain (10) · Nervous System Diseases (9) · Pathologic Processes (6) · Wounds and Injuries (6) · Central Nervous System Diseases (5) · Postoperative Complications (5) · Spinal Cord Diseases (4) · Trauma, Nervous System (4) · Nutritional and Metabolic Diseases (3) · Respiratory Tract Diseases (3)
Sodium Chloride (4) · Ropivacaine (3) · Dexamethasone (2) · Dexmedetomidine (2) · Analgesia, Patient-Controlled (1) · Anesthesia (1) · Bupivacaine (1) · Continuous Positive Airway Pressure (1) · Control Groups (1) · Electric Stimulation Therapy (1) · Magnesium Sulfate (1) · Magnetic Resonance Imaging (1) · Nursing Education Research (1) · Propofol (1) · Psychological Tests (1)
Poznan University of Medical Sciences (4) · Istituto Ortopedico Rizzoli (2) · Peking University Third Hospital (2) · University Health Network, Toronto (2) · AUSL Romagna Rimini (1) · Alexander T. Yahanda (1) · Aristotle University Of Thessaloniki (1) · Association of Future African Neurosurgeons, Yaounde, Cameroon (1) · Ataturk University (1) · Cortexx Medical Intelligence (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · GCS Ramsay Santé pour l'Enseignement et la Recherche (1) · IRCCS Eugenio Medea (1) · KU Leuven (1) · Korea University Guro Hospital (1)
United States (8) · Italy (5) · Poland (4) · Turkey (Türkiye) (4) · Canada (3) · France (3) · Belgium (2) · Australia (1) · Brazil (1) · Cameroon (1) · Chile (1) · China (1) · Egypt (1) · Greece (1) · Lebanon (1)
Alessandro Olivi, MD (1) · Anouk Smeets, MD, PhD (1) · Brian F Saway, MD (1) · Corinna Zygourakis, MD (1) · Domenico P Santonastaso, MD (1) · Dr. Julio Furlan (1) · Georgia Tsaousi (1) · Giuseppe Andreoni (1) · Jason Chui, MBChB (1) · Jessica Barley, PhD (1) · Julio C Furlan, MD, FRCPC (1) · Katarzyna Wieczorowska-Tobis, MD PhD (1)
PMID 23832767, PMID 29932049, PMID 30944886, PMID 31948345, PMID 34366759, PMID 34542672, PMID 35271152, PMID 36196076, PMID 37254058, PMID 37955445, PMID 40325670, PMID 40480676, PMID 41583840, PMID 41806994, PMID 42246693