16 completed, 6 unknown, 4 recruiting, 1 not yet recruiting. 28 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 28 | Completed 16, Unknown 6, Recruiting 4, Not yet recruiting 1, Terminated 1 |
Follow Spasm: new trials by email Literature Review of Spasm trials Research Report on Spasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| "Effect of Preoperative Submucosal Dexamethasone on Postoperative Discomfort After Mandibular Third Molar Surgery" Dexamethasone, No intervention - Impacted Mandibular Third Molar, Postoperative Pain | Phase 4 | Not yet recruiting | Hayat Abad Medical Complex, Peshawar | 268 | 2026-05-01 | 2026-05-01 |
| Magnesium and Cramping Magnesium sulfate, Ketamine, Placebo - Uterine Cramps, Postoperative Pain Management | Phase 4 | Recruiting | Corewell Health East | 150 | 2025-07-29 | 2025-08-20 |
| Effects of DaxibotulinumtoxinA for Blepharospasm and Hemifacial Spasm DaxibotulinumtoxinA - Benign Essential Blepharospasm, Hemifacial Spasm | Phase 4 | Recruiting | Montefiore Medical Center | 40 | 2025-02-11 | 2026-04-23 |
| Efficacy of Botox Injection of the Masticatory Muscles in Head &Neck Cancer Patients with Trismus After Radiotherapy Echo-guided Botox injection, echo-guided normal saline injection - Trismus, Head and Neck Cancer | Phase 4 | Recruiting | National Taiwan University Hospital | 120 | 2024-12-01 | 2024-12-16 |
| Submucosal Dexamethasone for Control of Post-operative Pain, Trismus, and Swelling After Mandibular Third Molar Surgery Dexamethasone, Normal Saline - Impacted Mandibular Third Molar Extraction | Phase 4 | Completed | PAEC General Hospital, Islamabad | 70 | 2024-10-01 | 2025-12-02 |
| The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema Dexamethasone Sodium Phosphate Injection, Normal Saline (Placebo) - Swelling/ Edema, Trismus | Phase 4 | Recruiting | King Abdulaziz University | 66 | 2024-02-01 | 2025-05-01 |
| Comparison of the Effects of Intraoral Postoperative Dexamethasone Applications After Mandibular Third Molar Surgery In this group, patients received 8 mg IM dexamethasone injection into the masseter muscle after impacted tooth surgery., 8 mg IM dexamethasone injection into the pterygoid cavity after impacted tooth surgery. - Wisdom Teeth, Edema Face | Phase 4 | Completed | Afyonkarahisar Health Sciences University | 20 | 2023-04-28 | 2024-09-20 |
| Lornoxicam Versus Etodolac After Third Molar Surgery Lornoxicam 8 Mg Oral Tablet - Pain, Acute, Edema | Phase 4 | Completed | Kutahya Health Sciences University | 20 | 2022-07-20 | 2023-01-11 |
| Adjunct Treatment With Cariprazine for Adults With Attention-deficit/Hyperactivity Disorder Cariprazine - Attention Deficit Hyperactivity Disorder | Phase 4 | Unknown | Dr. Martin A. Katzman | 15 | 2021-12-01 | 2021-12-14 |
| Minimizing Pain During Office Intradetrussor Botox Injection Bicarbonate protocol, Standard protocol - Overactive Bladder, Overactive Detrusor | Phase 4 | Completed | Boston Urogynecology Associates | 85 | 2020-08-15 | 2025-03-06 |
| Different Oral Doses of Clindamycin in Preventing Post-operative Sequelae of Lower Third Molar Surgery Dalacin C - Impacted Third Molar Tooth, Impacted Molar | Phase 4 | Unknown | Oral and Maxillofacial Surgery Clinic, Poland | 300 | 2020-02-01 | 2022-03-07 |
| Clinical Efficacy of Diazepam After Whiplash Diazepam Tablets - Whiplash Injuries, Whiplash Injury of Cervical Spine | Phase 4 | Completed | Edin Mešanović | 89 | 2020-01-01 | 2024-12-04 |
| Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema Hyaluronidase Injection mesomedica, Dexamethasone dekort - Edema, Pain | Phase 4 | Completed | Hacettepe University | 60 | 2019-12-01 | 2022-07-20 |
| The Efficacy of A-PRF+ on Postoperative Outcomes Following Surgical Removal of Impacted Mandibular Third Molars (A-PRF+: Advanced Platelet Rich Fibrin) A-PRF+ - PRF | Phase 4 | Completed | University of Medicine and Pharmacy at Ho Chi Minh City | 76 | 2019-10-01 | 2023-04-24 |
| Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery? Dexketoprofen Trometamol, Dexamethasone 21-Phosphate, Therapeutic Elastic Bandage - Third Molar Surgery | Phase 4 | Completed | Tokat Gaziosmanpasa University | 52 | 2019-05-02 | 2019-12-17 |
| Evaluation of the Effects of Pre-operative Deflazacort on Post-operative Pain, Edema and Trismus Deflazacort 30 MG Oral Tablet, Sugar pill - Impacted Third Molar Tooth | Phase 4 | Unknown | Yuzuncu Yil University | 35 | 2018-12-15 | 2023-08-22 |
| Topical Arnica and Mucopolysaccharide Polysulfate on Postoperative Pain, Edema and Trismus : Arnica montana, Mucopolysaccharide polysulfate, Control group - Impacted Third Molar Tooth | Phase 4 | Completed | Abant Izzet Baysal University | 60 | 2018-12-01 | 2020-09-01 |
| Evaluation of the Effects of Irrigation of the Extraction Socket With Rifamycine Rifamycine, Saline Solution - Impacted Third Molar Tooth | Phase 4 | Unknown | Yuzuncu Yil University | 35 | 2018-11-15 | 2023-08-22 |
| Treatments for Fathers With ADHD and Their At-Risk Children (Fathers Too) Vyvanse, Behavioral Parent Training, Methylphenidate - Attention Deficit/Hyperactivity Disorder (ADHD) | Phase 4 | Completed | Seattle Children's Hospital | 19 | 2015-12-01 | 2018-09-12 |
| Pretarsal Versus Preseptal Botulinum Toxin for Patients With Eyelid Spasm Botulinum Toxin Type A 100Unit/Vial (Product), Saline Solution for Injection - Blepharospasm, Hemifacial Spasm | Phase 4 | Completed | The University of Hong Kong | 100 | 2015-07-01 | 2019-04-26 |
Showing 20 of 28. Sign in to see all of them.
Trismus (16) · Edema (9) · Pain (9) · Attention Deficit Disorder with Hyperactivity (5) · Pain, Postoperative (4) · Hemifacial Spasm (2) · Tooth, Impacted (2) · Acute Pain (1) · Agnosia (1) · Asperger Syndrome (1) · Autistic Disorder (1) · Benign essential blepharospasm (1) · Blepharospasm (1) · Child Development Disorders, Pervasive (1)
Nervous System Diseases (28) · Neurologic Manifestations (28) · Neuromuscular Manifestations (28) · Pathological Conditions, Signs and Symptoms (28) · Signs and Symptoms (28) · Pathologic Processes (6) · Attention Deficit and Disruptive Behavior Disorders (5) · Mental Disorders (5) · Neurodevelopmental Disorders (5) · Pain (5) · Postoperative Complications (5) · Stomatognathic Diseases (4) · Infections (2) · Mouth Diseases (2)
Saline Solution (4) · Methylphenidate (3) · 5,10-dihydro-5-methylphenazine (2) · Botulinum Toxins, Type A (2) · Dexamethasone (2) · Tablets (2) · dexamethasone 21-phosphate (2) · 21-benzyloxy-9alpha-fluoro-16alpha-methylpregna-1,4-dien-11beta,17alpha-diol-3,20-dione (1) · AIEOP acute lymphoblastic leukemia protocol (1) · Arnicae flos extract (1) · Atomoxetine Hydrochloride (1) · Clindamycin (1) · Control Groups (1) · Diazepam (1) · Etodolac (1)
Yuzuncu Yil University (2) · Abant Izzet Baysal University (1) · Afyonkarahisar Health Sciences University (1) · Boston Urogynecology Associates (1) · Children's Hospital Medical Center, Cincinnati (1) · Corewell Health East (1) · Danish Pain Research Center (1) · Dr. Martin A. Katzman (1) · Edin Mešanović (1) · Grifols Therapeutics LLC (1) · Hacettepe University (1) · Hayat Abad Medical Complex, Peshawar (1) · Hayat Pharmaceutical Co. PLC (1) · Icahn School of Medicine at Mount Sinai (1) · King Abdulaziz University (1)
United States (8) · Turkey (Türkiye) (7) · Bosnia and Herzegovina (1) · Canada (1) · Cyprus (1) · Denmark (1) · Iran (1) · Pakistan (1) · Poland (1) · Saudi Arabia (1) · Taiwan (1) · Vietnam (1)
Anna Janas-Naze, DMD,PhD,Prof (1) · Anne Barmettler, MD (1) · Bijan Movahedian, Oral and maxillofacial surgeon (1) · Bryan King, MD (1) · Christopher McDougle, MD (1) · Dr Kanza Ateeque, BDS (1) · James Dziura, MPH, PhD (1) · James McCracken, MD (1) · Jeffrey Newcorn, MD (1) · Kumar Alagappan, MD (1) · Kurt Schulz, PhD (1) · Lawrence Scahill, MSN, PhD (1) · Marcus M Marcet, MD (1) · Mark A Stein, PhD (1) · Martin A Katzman, MD (1)
PMID 16197668, PMID 19506571, PMID 21845387, PMID 23512235, PMID 2469747, PMID 25853044, PMID 26910697, PMID 32803439, PMID 32855917, PMID 32919832, PMID 32950350, PMID 33653320, PMID 34447785, PMID 34713808, PMID 35027927, PMID 35201607, PMID 37811711, PMID 37913818, PMID 39215323, PMID 40025238, PMID 40181005, PMID 42816859, PMID 7613277
2023 (1), R01MH083707 (1), R01MH095766 (1)