20 completed, 8 unknown, 3 recruiting, 2 terminated. 16 Not applicable, 3 Phase 2, 3 Phase 3, 3 Phase 4, 2 Phase 1.
Follow Small Intestinal Bacterial Overgrowth: new trials by email Literature Review of Small Intestinal Bacterial Overgrowth trials Research Report on Small Intestinal Bacterial Overgrowth
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial of a Multi-Component Nutritional Supplement in Hydrogen-Dominant Small Intestinal Bacterial Overgrowth AV1PD1A - Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Small Intestinal Bacterial Overgrowth | Not applicable | Completed | National University of Natural Medicine | 9 | 2025-10-10 | 2026-05-12 |
| Methane and Hydrogen Breath Test for the Diagnosis of Small Intestinal Bacterial Overgrowth Small Intestinal Bacterial Overgrowth | Unknown | Shanghai Jiao Tong University School of Medicine | 750 | 2024-09-01 | 2024-08-27 | |
| The Safety And Efficacy Of A Probiotic Intervention On Lactulose Hydrogen Breath Test-Positive Patients And Related Gastrointestinal Symptoms Probiotic - Small Intestinal Bacterial Overgrowth, SIBO | Not applicable | Active not recruiting | Nimble Science Ltd. | 105 | 2024-07-10 | 2026-09-30 |
| Pilot Feasibility Study of Fecal Microbiota Transplant for the Treatment of Small Intestinal Bacterial Overgrowth Fecal Microbiota Transplant - Small Intestinal Bacterial Overgrowth | Phase 1 | Recruiting | McMaster Children's Hospital | 20 | 2024-03-11 | 2025-08-21 |
| Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan® CapScan collection capsule - Small Intestinal Bacterial Overgrowth | Phase 1 | Recruiting | Envivo Bio Inc | 34 | 2024-02-15 | 2025-06-11 |
| The Low FODMAP Diet in Individuals With Small Intestinal Bacterial Overgrowth (SIBO) Low FODMAP Diet, Healthy Eating Diet - SIBO, Small Intestinal Bacterial Overgrowth | Not applicable | Completed | Warsaw University of Life Sciences | 51 | 2024-02-08 | 2026-02-24 |
| Gut Microbiome-Metabolome Profiling in H. Pylori-SIBO Comorbidity 13C-Urea Breath Test, Hydrogen-Methane Breath Test - Gut Microbiota, Metabolic Profiles | Completed | Zhongshan Hospital (Xiamen), Fudan University | 42 | 2024-01-31 | 2026-03-25 | |
| Therapeutic Effect of Olive Leaf Tea on SIBO Olive leaf tea - Small Intestinal Bacterial Overgrowth, Gastrointestinal Disorder, Functional | Not applicable | Completed | University of Veterinary and Animal Sciences, Lahore - Pakistan | 50 | 2023-06-01 | 2024-01-12 |
| The Efficacy of Probiotics as an Adjunct to Treatment of SIBO With Rifaximin Rifaximin (Xifaxan) 1200mg/day, Probiotic, XIFAXAN® (Rifaximin) 1600mg/day - Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth | Not applicable | Completed | Pomeranian Medical University Szczecin | 129 | 2023-04-01 | 2025-12-04 |
| Clinical Study of Fecal Microbiota Transplantation in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO) Fecal microbiota transplantation - Small Intestinal Bacterial Overgrowth, Fecal Microbiota Transplantation | Not applicable | Completed | Shanghai 10th People's Hospital | 66 | 2022-09-10 | 2023-12-08 |
| Rifaximin's Effect on Covert Hepatic Encephalopathy With SIBO and Gastrointestinal Dysmotility Rifaximin - Cirrhosis, Liver, Minimal Hepatic Encephalopathy | Phase 3 | Withdrawn | MetroHealth Medical Center | 2021-09-15 | 2025-12-24 | |
| Feasibility of a New Diagnostic Device to Assess Small Intestinal Dysbiosis in Routine Clinical Setting. Atmo Gas Capsule, Glucose Breath Test, Fructoolifosaccharides (FOS) Breath Test - Small Intestinal Bacterial Overgrowth | Not applicable | Unknown | Atmo Biosciences Pty Ltd | 150 | 2021-07-14 | 2024-01-30 |
| Rifaximin Therapy vs Low FODMAP Diet In IBS Rifaximin, Low FODMAP diet - Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth | Phase 4 | Unknown | University of Malaya | 100 | 2021-04-22 | 2023-05-16 |
| High-fat Diet (HFD) and Small Intestinal Microbiome HFD - Microbial Colonization, Small Intestinal Bacterial Overgrowth | Not applicable | Completed | Insel Gruppe AG, University Hospital Bern | 10 | 2021-03-01 | 2025-06-13 |
| Hydrogen and Methane Breath Test Questionnaire Questionnaire - Small Intestinal Bacterial Overgrowth | Completed | The Functional Gut Clinic | 1040 | 2021-02-10 | 2023-06-02 | |
| Effect of a Probiotic Formula on Reducing SIBO in IBS Patients Probiotic, Rifaximin - Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth | Not applicable | Terminated | AB Biotics, SA | 8 | 2020-11-20 | 2022-11-08 |
| Efficacy of AEMCOLO (Rifamycin SV MMX) in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO) AEMCOLO (Rifamycin SV MMX) - Small Intestinal Bacterial Overgrowth, Gastrointestinal Disease | Phase 2 | Unknown | Bradley Connor | 30 | 2020-06-30 | 2022-05-05 |
| Intestinal Adsorbent and Breath Gas Levels Intestinal adsorbent - Gastroesophageal Reflux, Small Intestinal Bacterial Overgrowth | Not applicable | Completed | Dr Anthony Hobson | 20 | 2019-08-13 | 2022-04-27 |
| The Small Intestine Bacterial Overgrowth Study Pilot Treatment Protocol, Standard of Care - Systemic Sclerosis, Small Intestinal Bacterial Overgrowth | Not applicable | Unknown | Canadian Scleroderma Research Group | 500 | 2019-02-15 | 2019-10-17 |
| Comparative Assessment of Radioisotope Glucose and Breath Test Using Isotope (Tc99m-Sulfur Colloid) to label glucose and administer this directly into duodenum. - Small Intestinal Bacterial Overgrowth | Unknown | Augusta University | 25 | 2019-01-21 | 2020-08-05 |
Showing 20 of 37. Sign in to see all of them.
Irritable Bowel Syndrome (8) · Gastrointestinal Diseases (3) · Diarrhea (2) · Gastroesophageal Reflux (2) · Liver Cirrhosis (2) · Scleroderma, Systemic (2) · Abdominal Pain (1) · Communicable Diseases (1) · Constipation (1) · Critical Illness (1) · Dilatation, Pathologic (1) · Dysbiosis (1) · Eosinophilic Esophagitis (1) · Fecal Incontinence (1) · Fructose Intolerance (1)
Digestive System Diseases (14) · Pathological Conditions, Signs and Symptoms (10) · Gastrointestinal Diseases (9) · Intestinal Diseases (9) · Colonic Diseases (8) · Colonic Diseases, Functional (8) · Pathologic Processes (5) · Signs and Symptoms (4) · Signs and Symptoms, Digestive (4) · Connective Tissue Diseases (2) · Deglutition Disorders (2) · Disease Attributes (2) · Esophageal Diseases (2) · Esophageal Motility Disorders (2) · Fibrosis (2)
Rifaximin (10) · Probiotics (3) · FODMAP Diet (2) · Fecal Microbiota Transplantation (2) · Metronidazole (2) · Anti-Bacterial Agents (1) · Breath Tests (1) · Ciprofloxacin (1) · Clinical Protocols (1) · Control Groups (1) · Culture Techniques (1) · Diet, Healthy (1) · Fluoroquinolones (1) · Genes, fos (1) · Standard of Care (1)
Augusta University (3) · Coordinación de Investigación en Salud, Mexico (2) · Indiana University (2) · AB Biotics, SA (1) · Atmo Biosciences Pty Ltd (1) · Atrium Innovations (1) · Bradley Connor (1) · Canadian Scleroderma Research Group (1) · Cedars-Sinai Medical Center (1) · Children's Hospital Los Angeles (1) · Chinese PLA General Hospital (1) · Dr Anthony Hobson (1) · Envivo Bio Inc (1) · Henry C. Lin, MD (1) · Insel Gruppe AG, University Hospital Bern (1)
United States (15) · China (3) · Australia (2) · Canada (2) · Mexico (2) · Poland (2) · United Kingdom (2) · Greece (1) · India (1) · Malaysia (1) · Pakistan (1) · Spain (1) · Switzerland (1)
Anthony Hobson (1) · Anthony Hobson, PhD (1) · Ashok K Tuteja, MD MPH (1) · Brynie S Collins, MD (1) · George Triadafilopoulos (1) · Henry C Lin, MD (1) · Jing-yuan Fang, MD,Ph.D (1) · John Wo, MD (1) · Jun Wan (1) · Karin S Gilkison, MD, MPH (1) · Katarzyna Kozlowska-Petriczko, MD, PhD (1) · Kee-Huat Chuah, MBBS (1) · Melissa R Van Arsdall, MD (1)
PMID 19302262, PMID 20675008, PMID 20849805, PMID 21157444, PMID 21240023, PMID 25932262, PMID 26644276, PMID 30525951, PMID 31549334, PMID 38363519, PMID 39583431, PMID 40181268, PMID 41098003
R21DK078101 (1)