19 completed, 4 terminated, 3 recruiting, 2 not yet recruiting. 23 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 23 | Completed 15, Terminated 4, Not yet recruiting 2, Recruiting 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of a Probiotic Formula in Mild Cognitive Impairement Probiotic Arm, Placebo - Mild Cognitive Impairment (MCI) | Not applicable | Recruiting | Universidad Complutense de Madrid | 100 | 2026-03-21 | 2026-07-16 |
| Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial Lactiplantibacillus plantarum Probiotic Mixture, Placebo comparator containing maltodextrin - MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Fatty Liver Disease, Nonalcoholic | Phase 2 | Recruiting | AB Biotics, SA | 60 | 2026-03-20 | 2026-04-30 |
| Clinical Trial to Assess the Efficacy and Safety of a Cosmetic Product in Individuals Showing Signs of Cutaneous Aging. Active cream - Skin, Skin Ageing | Not applicable | Not yet recruiting | AB Biotics, SA | 45 | 2026-02-01 | 2026-01-15 |
| Examine Impact of Topical Application of Active Versus Placebo on the Skin Microbiome in Sensitive Skin. Active Cream, Placebo Cream without active substance - Skin, Skin Microbiome | Not applicable | Not yet recruiting | AB Biotics, SA | 45 | 2026-02-01 | 2026-03-06 |
| Impact of a Probiotic Combination on Quality of Life and Symptoms in Peri- and Postmenopausal Women Probiotic, Placebo - Menopause | Not applicable | Completed | AB Biotics, SA | 245 | 2024-09-16 | 2025-12-04 |
| Impact of a Probiotic-based Formula on Digestive Symptoms and Mood in Ultra Marathon Runners Experimental product, Control product - Signs and Symptoms | Not applicable | Completed | AB Biotics, SA | 277 | 2023-08-15 | 2024-09-19 |
| Evaluation of the Vaginal Colonization of Two New Lactobacillus Strains After Oral Administration in Healthy Volunteers Experimental 1, Experimental 2, Placebo - Healthy | Not applicable | Completed | AB Biotics, SA | 48 | 2023-02-15 | 2023-07-20 |
| Effect of Probiotics on Infant's Fecal Microbiota Composition Food Supplement 1, Food Supplement 2, Placebo - Microbial Colonization | Not applicable | Recruiting | AB Biotics, SA | 120 | 2022-06-01 | 2025-02-11 |
| Efficacy and Safety of L. Plantarum and P. Acidilactici in Children With Upper Respiratory Tract Infections Probiotic, Placebo - Upper Respiratory Tract Infections, Pharyngitis | Not applicable | Terminated | AB Biotics, SA | 80 | 2022-03-08 | 2023-10-17 |
| Effect of a Multi-strain Probiotic Formulation on Immune Response to Influenza Vaccination Food Supplement, Placebo - Influenza Vaccine | Not applicable | Completed | AB Biotics, SA | 140 | 2021-10-26 | 2022-07-26 |
| Efficacy and Safety of a Probiotic Composition as Adjunct in MAFL Management Probiotic composition, Placebo - Non Alcoholic Fatty Liver | Not applicable | Completed | AB Biotics, SA | 100 | 2021-03-31 | 2022-02-24 |
| Effect of a Probiotic Formula on Reducing SIBO in IBS Patients Probiotic, Rifaximin - Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth | Not applicable | Terminated | AB Biotics, SA | 8 | 2020-11-20 | 2022-11-08 |
| Probiotic Intervention, Bile Acids and Lipid Metabolism Metabolic Profile in Healthy Overweight Subjects. Probiotic preparation of three Lactobacillus plantarum strains (CECT 7527, CECT 7528, CECT 7529) - Probiotic Intervention | Not applicable | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 20 | 2020-09-01 | 2022-06-07 |
| Efficacy of L. Plantarum and P. Acidilactici in Adults With SARS-CoV-2 and COVID-19 Probiotics, Placebo - SARS-CoV Infection | Not applicable | Completed | AB Biotics, SA | 300 | 2020-08-19 | 2021-05-06 |
| Interventional Study to Evaluate the Effect of the Oral Administration of L.Plantarum on Vaginal Microbiota Lactobacillus plantarum - Vaginal Infection | Not applicable | Completed | AB Biotics, SA | 30 | 2019-04-15 | 2020-07-08 |
| Prospective Study to Determine the Factors Influencing Infant Colic AB-Kolicare, Reuteri gotas - Infant Colic | Not applicable | Completed | AB Biotics, SA | 112 | 2019-03-01 | 2026-02-24 |
| Observational Prospective Study With Probiotic Supplementation on Infants With FGDI Probiotic - Functional Gastrointestinal Disorders, Infantile Colic | Completed | AB Biotics, SA | 36 | 2018-08-15 | 2021-06-29 | |
| Combined Nutritional Therapies for the Treatment of Ulcerative Colitis A: 1 dosis, B: 2 dosis - Colitis, Ulcerative | Not applicable | Terminated | AB Biotics, SA | 12 | 2018-03-08 | 2020-07-08 |
| Effect of Probiotics on Recurrent Urinary Tract Infections Food supplement, Placebo - Urinary Tract Infections | Not applicable | Terminated | AB Biotics, SA | 106 | 2018-01-01 | 2026-01-29 |
| Clinical Trial to Evaluate the Addition to an Antiretroviral Treatment of a Probiotic Probiotic, Prebiotic, Placebo - HIV, Premature Aging | Not applicable | Completed | AB Biotics, SA | 89 | 2017-12-18 | 2020-07-08 |
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Colic (2) · Hypercholesterolemia (2) · Non-alcoholic Fatty Liver Disease (2) · Aging, Premature (1) · Bipolar Disorder (1) · COVID-19 (1) · Cognitive Dysfunction (1) · Colitis, Ulcerative (1) · Communicable Diseases (1) · Dental Plaque (1) · Depressive Disorder, Major (1) · Gastrointestinal Diseases (1) · Inflammation (1) · Influenza, Human (1) · Irritable Bowel Syndrome (1)
Probiotics (10) · Dietary Supplements (2) · Control Groups (1) · Ibuprofen (1) · Lovastatin (1) · Pharmacogenomic Testing (1) · Prebiotics (1) · Rifaximin (1) · Therapeutics (1)
Spain (19) · Mexico (5) · France (1) · Italy (1)
Ariana Salavert, PhD (2) · Jordi Espadaler Mazo, PhD (2) · Alex Mira, Dr. (1) · Ana Maria Aldea Perona, PhD (1) · Ariana Salavert, Ph. D. (1) · David Gendre, M.D. (1) · Eduard Ferres Padro, MD (1) · Eduard Vieta, MD, PhD (1) · Enrique Conde (1) · Ester Moreno Artero, PhD (1) · Jose Nart Molina, DMD (1) · Maura Sticco, MD (1) · Pedro Gutierrez-Castrellon, MD, PhD (1)
PMID 17081293, PMID 19766548, PMID 24187469, PMID 24912386, PMID 26832746, PMID 28002391, PMID 28705252, PMID 28923425, PMID 29416317, PMID 29728861, PMID 30113661, PMID 32027858, PMID 32443684, PMID 32595361, PMID 32645713, PMID 32670091, PMID 32728349, PMID 32733907, PMID 32780788, PMID 32787470, PMID 33578007, PMID 33981389, PMID 35095783, PMID 36569851, PMID 38525555, PMID 39390276, PMID 40568349, PMID 40772934, PMID 42549656