35 completed, 18 unknown, 9 recruiting, 4 active not recruiting. 36 Not applicable, 5 Phase 2, 5 Phase 4, 2 Phase 1, 1 Phase 3.
Follow Sleep-disordered Breathing: new trials by email Literature Review of Sleep-disordered Breathing trials Research Report on Sleep-disordered Breathing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep Apnea Combination device and drug: Unilateral hypoglossal nerve stimulation & atomoxetine-plus-oxybutynin (HGNS+AtoOxy), Unilateral hypoglossal nerve stimulation (HGNS), active comparator condition, Atomoxetine-plus-oxybutynin (80/5 mg) (AtoOxy), active comparator condition - Obstructive Sleep Apnea, Sleep-disordered Breathing | Phase 1 / Phase 2 | Recruiting | Brigham and Women's Hospital | 24 | 2026-09-01 | 2026-09-21 |
| Sleep Medicine Education in Dental Schools and Residency Programs in Italian Universities Sleep medicine education questionnaire - Sleep Apnea Syndrome, Obstructive, Dental Education | Active not recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 70 | 2026-06-03 | 2026-06-17 | |
| Evolution of Hypoxic Burden and Sympathetic/Parasympathetic Balance in Patients With Pulmonary Hypertension Standard Clinical and Functional Assessment, Overnight Polysomnography - Precapillary Pulmonary Hypertension, Pulmonary Arterial Hypertension | Not applicable | Not yet recruiting | University Hospital, Rouen | 60 | 2026-06-01 | 2026-04-15 |
| Impact of Nocturnal Hypoxemia on Glucose in High Altitude Sleep Disordered Breathing Compressed Air, Supplemental Oxygen - Sleep-Disordered Breathing, Glucose Intolerance | Not applicable | Withdrawn | Johns Hopkins University | 2025-12-01 | 2026-01-07 | |
| Sleep Quality in Patients With Non-cystic Fibrosis Bronchiectasis Pittsburgh Sleep Quality Index - Bronchiectasis, Sleep-Disordered Breathing | Active not recruiting | Assiut University | 200 | 2025-10-14 | 2026-10-27 | |
| Exploring the Patterns of Sleep Disordered Breathing in Systemic Sclerosis Patients Polysomnography (PSG) - Systemic Sclerosis, Sleep-Disordered Breathing | Not yet recruiting | Assiut University | 30 | 2025-09-20 | 2025-09-16 | |
| Respiratory Progression in Adults With Duchenne Muscular Dystrophy. Duchenne Muscular Dystrophy (DMD), Respiratory Function Decline | Recruiting | Istituto Giannina Gaslini | 150 | 2025-09-09 | 2026-10-19 | |
| Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia Methadone, Fentanyl/Hydromorphone - Pain, Postoperative, Tonsillar Hypertrophy | Phase 4 | Recruiting | Duke University | 440 | 2024-11-21 | 2025-12-05 |
| Validation of Belun Ring Gen3 Deep Learning Algorithms With Subxiphoid Body Sensor Belun Ring, Belun Cor - Sleep-Disordered Breathing, Sleep Architecture | Not applicable | Active not recruiting | Belun Technology Company Limited | 79 | 2024-07-19 | 2026-09-30 |
| HighCycle Study: Effect of High Altitude on Sleep Disordered Breathing in Women Related to Their Menstrual Cycle Phase Exposure to 3600 m - Sleep-Disordered Breathing | Completed | University of Zurich | 91 | 2024-07-15 | 2026-06-05 | |
| HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men Acetazolamide, Placebo - Sleep-Disordered Breathing | Phase 4 | Completed | University of Zurich | 303 | 2024-07-15 | 2026-06-05 |
| Comparison of Two Reeducation Methods in Children With Persistent Sleep Apnea, a Randomized Controlled Trial Soft Oral Appliance - Obstructive Sleep Apnea of Child, Sleep-Disordered Breathing | Not applicable | Recruiting | Université de Montréal | 60 | 2024-03-20 | 2024-10-09 |
| Impact of Pulmonary Endarterectomy on Sleep-Related Breathing Disorders in CTEPH: The IPES Trial Pulmonary endarterectomy - Sleep-Disordered Breathing, Chronic Thromboembolic Pulmonary Hypertension | Unknown | Marmara University | 100 | 2023-12-20 | 2023-10-04 | |
| Managing Opioid Related Sleep Apnea With Acetazolamide Acetazolamide, Placebo - Sleep-Disordered Breathing, Obstructive Sleep Apnea | Phase 2 | Completed | University of California, San Diego | 39 | 2023-10-18 | 2026-03-10 |
| SMILES: Study of Montelukast in Sickle Cell Disease Montelukast, Oral Placebo - Anemia, Sickle Cell, Sleep-Disordered Breathing | Phase 2 / Phase 3 | Unknown | Great Ormond Street Hospital for Children NHS Foundation Trust | 200 | 2023-10-16 | 2023-11-01 |
| Home Initiation of Noninvasive Positive Pressure Ventilation in Children With Medical Complexity Home Initiation of NiPPV - Sleep-Disordered Breathing | Not applicable | Recruiting | The Hospital for Sick Children | 24 | 2023-06-21 | 2026-05-07 |
| Polysomnography Validation of the Sansa Device Sansa device - Sleep-Disordered Breathing | Not applicable | Completed | Huxley Medical, Inc. | 533 | 2023-06-01 | 2024-08-14 |
| The Meaning of Dopaminergic Pathway in Sleep Breathing Disorders. Polysomnography, Blood dopamine level measurement, Genetical test - Sleep Apnea, Sleep-Disordered Breathing | Enrolling by invitation | Wroclaw Medical University | 100 | 2023-06-01 | 2026-08-31 | |
| Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy Lateral pharyngoplasty, Tonsillectomy - Sleep-Disordered Breathing, Sleep Apnea Syndromes in Children | Not applicable | Recruiting | Loma Linda University | 160 | 2023-05-17 | 2026-02-23 |
| Tongue Morphology and Posterior Airway Space as Predictors of Response in Patientswith Hypoglossal Nerve Stimulation Therapy Ultrasonography - Obstructive Sleep Apnea, Sleep-Disordered Breathing | Completed | Cantonal Hospital, Baselland | 65 | 2023-05-15 | 2024-06-05 |
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Sleep Apnea Syndromes (74) · Sleep Apnea, Obstructive (22) · Sleep Apnea, Central (5) · Sleep Wake Disorders (5) · Snoring (4) · Heart Failure (3) · Sleep Initiation and Maintenance Disorders (3) · Stroke (3) · Hypertension (2) · Hypoxia (2) · Pain, Postoperative (2) · Pulmonary Arterial Hypertension (2) · Respiratory Insufficiency (2) · Tonsillitis (2) · Amyotrophic Lateral Sclerosis (1)
Dyssomnias (74) · Respiratory Tract Diseases (74) · Sleep Disorders, Intrinsic (74) · Apnea (73) · Nervous System Diseases (73) · Respiration Disorders (73) · Sleep Wake Disorders (69) · Pathological Conditions, Signs and Symptoms (22) · Signs and Symptoms (19) · Cardiovascular Diseases (11) · Mental Disorders (11) · Neurologic Manifestations (10) · Signs and Symptoms, Respiratory (10) · Heart Diseases (7) · Pathologic Processes (6)
Acetazolamide (3) · Continuous Positive Airway Pressure (3) · Polysomnography (3) · Adenoidectomy (1) · Botulinum Toxins, Type A (1) · Compact Disks (1) · Compressed Air (1) · Device Lead Extraction (1) · Diet (1) · Fentanyl (1) · Hydromorphone (1) · Ketorolac (1) · Methadone (1) · Occlusal Splints (1) · Palliative Care (1)
Belun Technology Company Limited (3) · Johns Hopkins University (3) · University of Michigan (3) · Assiut University (2) · Brigham and Women's Hospital (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · ResMed (2) · Shiphrah Biomedical Inc. (2) · Universitaire Ziekenhuizen KU Leuven (2) · University of Zurich (2) · AZ Delta (1) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Beijing Children's Hospital (1) · Cantonal Hospital, Baselland (1) · Centre for Sleep and Chronobiology, Canada (1)
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PMID 16585288, PMID 16676783, PMID 17372077, PMID 18049292, PMID 18577286, PMID 19837821, PMID 20880595, PMID 22272653, PMID 23066376, PMID 25411804, PMID 29510792, PMID 29776563, PMID 30505290, PMID 30545968, PMID 31517263, PMID 31605903, PMID 32179560, PMID 33608714, PMID 34104418, PMID 34629091, PMID 35286569, PMID 35554583, PMID 35878737, PMID 36633982, PMID 36661092, PMID 37185231, PMID 37510754, PMID 38051326, PMID 38095903, PMID 38241286, PMID 38422375, PMID 39172463, PMID 39302128, PMID 39382077, PMID 39633037, PMID 40094698, PMID 40183988, PMID 40192006, PMID 40526156, PMID 40589991, PMID 40590079, PMID 40875240, PMID 41350327, PMID 41821851, PMID 42013651, PMID 42421252
2023 (1), K23HL151880 (1), K23HL155730 (1), M01RR000096 (1), R01HD038461 (1), R01HD114678 (1), R01HL075078 (1), R01HL130552 (1), R01HL147261 (1), R01HL157256 (1)