16 unknown. 16 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Unknown 16 |
| Phase 2 | 3 | Unknown 3 |
Follow Septic Shock: new trials by email Literature Review of Septic Shock trials Research Report on Septic Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adjunctive Esketamine for Analgesia in Mechanically Ventilated Septic Shock Patients Esketamine, Saline, Remifentanil + propofol - Septic Shock, Mechanical Ventilation Complication | Phase 3 | Unknown | Nanfang Hospital, Southern Medical University | 124 | 2023-05-31 | 2023-11-22 |
| Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit Piperacillin/tazobactam or temocillin, Meropenem - Sepsis, Septic Shock | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 600 | 2023-03-11 | 2023-04-18 |
| Clinical Trial Comparing Noradrenaline (NA) Plus Placebo Versus Noradrenaline Plus Terlipressin (TP) in Septic Shock Noradrenaline plus Terlipressin - Septic Shock | Phase 3 | Unknown | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 152 | 2022-10-11 | 2023-04-27 |
| Impact of Aminoglycosides-based Antibiotics Combination and Protective Isolation on Outcomes in Critically-ill Neutropenic Patients With Sepsis: (Combination-Lock01) Aminoglycosides intervention, Lack of protective isolation intervention, No systematic aminoglycosides intervention - standard arm - Sepsis, Septic Shock | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 340 | 2022-09-01 | 2022-07-05 |
| Methylene Blue and Microcirculation in Septic Shock Methylene Blue, Norepinephrine infusion - Septic Shock | Phase 3 | Unknown | Cairo University | 32 | 2020-03-10 | 2020-03-05 |
| Steroids, Thiamine and Ascorbic Acid in Septic Shock STASIS - Septic Shock | Phase 3 | Unknown | Baqiyatallah Medical Sciences University | 80 | 2019-12-01 | 2019-10-22 |
| Treatment of Severe Infection With Antihyperlipidemia Drug Alirocumab Injectable Product, Saline Solution - Sepsis, Septic Shock | Phase 2 / Phase 3 | Unknown | Wolfson Medical Center | 712 | 2019-01-01 | 2018-08-16 |
| Lidocaine as an Adjuvant for Ketamine in Induction of Anesthesia in Septic Shock Patients Ketamine full dose, Ketamine half dose, Lidocaine - Septic Shock, Anesthesia | Phase 3 | Unknown | Cairo University | 36 | 2018-12-20 | 2018-11-21 |
| Shenfu Injection Improves Arterial Vascular Reactivity shenfu injection - Septic Shock, Shenfu | Phase 2 / Phase 3 | Unknown | Jianfeng Xie | 26 | 2018-12-01 | 2018-11-21 |
| Control Versus Liberal Cardiac Frequency in Patients in Sepse With Atrial Fibrillation of High Ventricular Response Amiodarone, 0.9% physiological solution - Sepsis, Septic Shock | Phase 3 | Unknown | University of Sao Paulo General Hospital | 126 | 2018-12-01 | 2018-10-23 |
| Clinical Trial of Antioxidant Therapy in Patients With Septic Shock Melatonin 5 mg, Vitamin C 1 GM Oral Tablet, Vitamin E 400 UNT - Oxidative Stress, Septic Shock | Phase 3 | Unknown | American British Cowdray Medical Center | 131 | 2018-07-23 | 2021-08-10 |
| Effect of Dexmedetomidine on Perfusion Index and Microcirculation in Severe Sepsis and Septic Shock Patients Dexmedetomidine - Septic Shock | Phase 3 | Unknown | Cairo University | 40 | 2017-01-04 | 2018-01-24 |
| What Should be the Next Vasopressor for Severe Septic Shock? Methylene Blue or Terlipressin Methylene Blue, Terlipressin - Septic Shock, Refractory Shock | Phase 3 | Unknown | Ramathibodi Hospital | 60 | 2016-12-01 | 2018-08-29 |
| Efficacy of Melatonin in Patients With Severe Sepsis or Septic Shock Melatonin - Severe Sepsis, Septic Shock | Phase 3 | Unknown | Aragon Institute of Health Sciences | 110 | 2013-05-01 | 2013-05-21 |
| Methylene Blue in Severe Sepsis and Septic Shock Intravenous methylene blue administration, Placebo - Severe Sepsis, Septic Shock | Phase 3 | Unknown | Seoul National University Hospital | 354 | 2013-02-01 | 2015-11-18 |
| Levosimendan Versus Dobutamine in Shock Patients Levosimendan, Dobutamine - Cardiogenic Shock, Septic Shock | Phase 2 / Phase 3 | Unknown | Wentworth Area Health Services | 40 | 2004-10-01 | 2005-06-24 |
Shock, Septic (16) · Sepsis (8) · Shock (2) · Agnosia (1) · Atrial Fibrillation (1) · Heart Failure (1) · Hematologic Neoplasms (1) · Infections (1) · Neoplasms (1) · Shock, Cardiogenic (1) · Ventricular Fibrillation (1)
Inflammation (16) · Pathologic Processes (16) · Pathological Conditions, Signs and Symptoms (16) · Systemic Inflammatory Response Syndrome (16) · Infections (15) · Shock (14) · Sepsis (8) · Cardiovascular Diseases (2) · Heart Diseases (2) · Arrhythmias, Cardiac (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Infarction (1) · Ischemia (1) · Myocardial Infarction (1)
Saline Solution (3) · Melatonin (2) · Methylene Blue (2) · Norepinephrine (2) · Terlipressin (2) · Acetylcysteine (1) · Amiodarone (1) · Dexmedetomidine (1) · Dobutamine (1) · Esketamine (1) · Fluid Therapy (1) · IbsC protein, E coli (1) · Ketamine (1) · Lidocaine (1) · Meropenem (1)
Cairo University (3) · Assistance Publique - Hôpitaux de Paris (2) · American British Cowdray Medical Center (1) · Aragon Institute of Health Sciences (1) · Baqiyatallah Medical Sciences University (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · Jianfeng Xie (1) · Nanfang Hospital, Southern Medical University (1) · Ramathibodi Hospital (1) · Seoul National University Hospital (1) · University of Sao Paulo General Hospital (1) · Wentworth Area Health Services (1) · Wolfson Medical Center (1)
Egypt (3) · Spain (2) · Australia (1) · Brazil (1) · China (1) · France (1) · Israel (1) · Mexico (1) · South Korea (1) · Thailand (1)
Ahmed Hasanin, Professor (1) · Ahmed Mukhtar, Professor (1) · Alfredo Aisa Alvarez, MD (1) · Amir Vahedian-Azimi, PhD (1) · Andrew C Miller, MD (1) · Kyuseok Kim, MD (1) · Mucio Tavares, MD (1) · Ziv Rosman, MD (1)