10 completed, 6 unknown, 4 recruiting, 2 not yet recruiting. 28 Phase 2, 8 Phase 3, 6 Phase 1.
Follow Rotator Cuff Injuries: new trials by email Literature Review of Rotator Cuff Injuries trials Research Report on Rotator Cuff Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Estradiol Supplementation and Rotator Cuff Repair Transdermal estrogen, Rotator Cuff Repair Surgery - Rotator Cuff Tears, Rotator Cuff Injuries | Phase 2 | Not yet recruiting | University of Utah | 58 | 2028-03-01 | 2026-03-19 |
| Repeated Injections of Adipose-derived Stem Cells in Rotator Cuff Tears Adipose derived stem cell injection, Placebo - Rotator Cuff Tears, Rotator Cuff Injuries | Phase 1 / Phase 2 | Not yet recruiting | University of Southern Denmark | 30 | 2026-10-01 | 2026-09-30 |
| The Effect of Oxytocin Nasal Spray on Preventing Postoperative Delirium in Elderly Patients Undergoing Orthopedic Surgery oxytocin nasal spray - Cervical Spinal Stenosis, Thoracic Spinal Stenosis | Phase 2 | Completed | Zhejiang University | 227 | 2025-06-01 | 2026-08-20 |
| Exploring the Feasibility of Silk Fibroin Surgical Mesh in Rotator Cuff Tears Repair Enhancement Silk fibroin surgical mesh - Rotator Cuff Tear | Phase 2 / Phase 3 | Recruiting | Weiliang Shen, Ph.D., M.D. | 20 | 2024-12-19 | 2025-01-09 |
| Tuberoplasty Versus Balloon Spacer biologic tuberoplasty, subacromial balloon spacer - Rotator Cuff Tears | Phase 1 / Phase 2 | Recruiting | University of Minnesota | 40 | 2024-12-02 | 2026-01-07 |
| CBD for Pain Following Orthopedic Shoulder Surgery Epidiolex, Placebo oral solution - Shoulder Osteoarthritis, Rotator Cuff Injuries | Phase 1 / Phase 2 | Recruiting | The Methodist Hospital Research Institute | 80 | 2024-05-24 | 2026-04-16 |
| Analysis of the Effect of Neuromuscular Electro-stimulation on the Performance of Isometric Rotator Cuff Strength. STRENGTH EVALUATION WITH ELECTROSTIMULATOR, STRENGTH EVALUATION WITHOUT ELECTROSTIMULATOR - Rotator Cuff Impingement Syndrome, Rotator Cuff Tendinitis | Phase 2 / Phase 3 | Unknown | University of Campinas, Brazil | 60 | 2023-09-01 | 2023-09-05 |
| Sex Hormone Supplementation and Rotator Cuff Repair: A Preliminary Randomized Trial Clomiphene Citrate, Rotator Cuff Repair - Rotator Cuff Tears | Phase 2 | Recruiting | University of Utah | 58 | 2023-03-09 | 2026-03-19 |
| Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R® Ortho-R/PRP - Rotator Cuff Tears | Phase 1 / Phase 2 | Unknown | ChitogenX Inc | 78 | 2022-07-26 | 2023-03-21 |
| Stromal Vascular Fraction (SVF) Cells for Non-Operative Treatment of Small Rotator Cuff Tears Tisseel Injectable Product, Stromal Vascular Fraction Cells - Rotator Cuff Tears | Phase 2 | Withdrawn | AdventHealth | 2022-01-09 | 2023-02-15 | |
| The Contribution of Platelet-Rich Plasma to the Surgical Treatment of Rotator Cuff Tear: An Experimental Study Arthroscopic repair of shoulder rotator cuff tear, PRP injection - Rotator Cuff Tear, Rotator Cuff Repair of the Shoulder | Phase 2 | Completed | KAT General Hospital | 51 | 2021-11-20 | 2026-07-08 |
| Can Testosterone Accelerate Injury Recovery After Arthroscopic Rotator Cuff Repair Testosterone cypionate, Placebos - Rotator Cuff Tears | Phase 2 / Phase 3 | Withdrawn | Orthopedic Institute, Sioux Falls, SD | 2021-08-01 | 2022-03-15 | |
| Mesenchymal Stem Cells in Rotator Cuff Repair Mesenchymal stem cell, Rotator cuff repair - Rotator Cuff Tear, Tendon Injuries | Phase 2 | Suspended | University of Sao Paulo | 44 | 2020-11-01 | 2022-10-19 |
| Phase 1/2 Clinical Study of TPX-115 in Patients With Partial-Thickness Rotator Cuff Tear TPX-115, Placebo - Rotator Cuff Injuries | Phase 1 / Phase 2 | Completed | Tego Science, Inc. | 49 | 2020-10-26 | 2023-05-18 |
| The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane in Total Shoulder Arthroplasty Ropivacaine, Dextrose - Rotator Cuff Injuries, Anesthesia; Functional | Phase 2 / Phase 3 | Terminated | University of Alberta | 17 | 2019-08-01 | 2024-06-06 |
| Stromal Vascular Fraction Cell Therapy to Improve the Repair of Rotator Cuff Tears Autologous Stomal Vascular Fraction Material, Ringer's solution - Rotator Cuff Tear, Muscle Atrophy | Phase 2 | Active not recruiting | Hospital for Special Surgery, New York | 56 | 2019-07-01 | 2026-09-03 |
| Ultrasound-Guided Treatments for Shoulder Pain in Wheelchair Users With Spinal Cord Injury Lipogems, Dexamethasone - Spinal Cord Injuries, Tendinopathy | Phase 2 | Unknown | Kessler Foundation | 24 | 2019-06-14 | 2022-10-14 |
| The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane Ropivacaine, Normal saline - Rotator Cuff Injury, Anesthesia; Functional | Phase 2 / Phase 3 | Completed | University of Alberta | 27 | 2019-05-01 | 2022-05-24 |
| Nonopioid Analgesia After Rotator Cuff Repair Celecoxib, Ketorolac, Gabapentin - Rotator Cuff Tear | Phase 2 | Completed | Henry Ford Health System | 70 | 2019-01-22 | 2024-04-02 |
| Treatment of Tendon Disease Using Autologous Adipose-derived Mesenchymal Stem Cells Autologous adipose-derived MSCs, Compound betamethasone - Rotator Cuff Tear, Lateral Epicondylitis | Phase 2 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 200 | 2018-10-01 | 2018-04-26 |
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Shoulder Pain (2) · Tendinopathy (2) · Tennis Elbow (2) · Bursitis (1) · Chronic Pain (1) · Emergence Delirium (1) · Muscular Atrophy (1) · Shoulder Dislocation (1) · Shoulder Fractures (1) · Shoulder Impingement Syndrome (1) · Spinal Cord Injuries (1) · Spinal Stenosis (1) · Tendon Injuries (1)
Rupture (28) · Shoulder Injuries (28) · Wounds and Injuries (28) · Tendon Injuries (27) · Musculoskeletal Diseases (7) · Neurologic Manifestations (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Joint Diseases (4) · Muscular Diseases (4) · Nervous System Diseases (3) · Pain (3) · Arm Injuries (2) · Arthralgia (2) · Elbow Injuries (2)
Ropivacaine (3) · Saline Solution (2) · Acetaminophen (1) · Adrenal Cortex Hormones (1) · Bupivacaine (1) · Buprenorphine (1) · Cannabidiol (1) · Celecoxib (1) · Clomiphene (1) · Dexamethasone (1) · Diazepam (1) · Diclofenac (1) · Epinephrine (1) · Fibrin Tissue Adhesive (1) · Gabapentin (1)
Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · University of Alberta (2) · University of Utah (2) · AdventHealth (1) · Asklepieion Voulas General Hospital (1) · Assiut University (1) · Bioinova, s.r.o. (1) · Cerimon Pharmaceuticals (1) · ChitogenX Inc (1) · Helse Møre og Romsdal HF (1) · Henry Ford Health System (1) · Hospital Italiano de Buenos Aires (1) · Hospital for Special Surgery, New York (1) · KAT General Hospital (1) · Kessler Foundation (1)
United States (10) · China (3) · Canada (2) · Greece (2) · South Korea (2) · Argentina (1) · Brazil (1) · Egypt (1) · Norway (1)
Rakesh V Sondekoppam, MD (2) · Vivian HY Ip, MD (2) · Allison Rao (1) · Ayman A Mamdouh, Ass Prof (1) · Dan Levitt, MD (1) · Joo Han Oh, Ph.D (1) · Kawser H Mohammed, Prof (1) · Keith M Baumgarten, MD (1) · Lars Frich (1) · Lora Pencheva, MD (1) · Mahmoud A Aly, Prof (1) · Oystein B Lian, md phd (1) · Patrick McCulloch, MD (1) · Petr Lesny, MD (1)
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