5 completed, 4 terminated, 2 not yet recruiting, 2 recruiting. 17 Phase 1, 6 Phase 2.
Follow Rotator Cuff Injuries: new trials by email Literature Review of Rotator Cuff Injuries trials Research Report on Rotator Cuff Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of BPC-157 on Recovery Following Rotator Cuff Repair Surgery BPC-157, Sham (No Treatment) - Rotator Cuff Tear | Phase 1 | Not yet recruiting | University of Arkansas | 30 | 2027-01-01 | 2026-09-03 |
| Repeated Injections of Adipose-derived Stem Cells in Rotator Cuff Tears Adipose derived stem cell injection, Placebo - Rotator Cuff Tears, Rotator Cuff Injuries | Phase 1 / Phase 2 | Not yet recruiting | University of Southern Denmark | 30 | 2026-10-01 | 2026-09-30 |
| Tuberoplasty Versus Balloon Spacer biologic tuberoplasty, subacromial balloon spacer - Rotator Cuff Tears | Phase 1 / Phase 2 | Recruiting | University of Minnesota | 40 | 2024-12-02 | 2026-01-07 |
| Stem Cell Treatment for Regeneration of the Rotator Cuff (Lipo-Cuff Study) Stem-cell treatment, Standard care - Rotator Cuff Tears, Rotator Cuff Injuries | Phase 1 | Enrolling by invitation | University of Southern Denmark | 30 | 2024-09-03 | 2026-10-08 |
| CBD for Pain Following Orthopedic Shoulder Surgery Epidiolex, Placebo oral solution - Shoulder Osteoarthritis, Rotator Cuff Injuries | Phase 1 / Phase 2 | Recruiting | The Methodist Hospital Research Institute | 80 | 2024-05-24 | 2026-04-16 |
| Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R® Ortho-R/PRP - Rotator Cuff Tears | Phase 1 / Phase 2 | Unknown | ChitogenX Inc | 78 | 2022-07-26 | 2023-03-21 |
| Optimal Dosing of IC-Green for Visualization of Rotator Cuff Vascularity Using Advanced Imaging Modality Arthroscopy Indocyanine Green - Rotator Cuff Tears | Phase 1 | Completed | NYU Langone Health | 20 | 2021-01-27 | 2026-07-09 |
| Phase 1/2 Clinical Study of TPX-115 in Patients With Partial-Thickness Rotator Cuff Tear TPX-115, Placebo - Rotator Cuff Injuries | Phase 1 / Phase 2 | Completed | Tego Science, Inc. | 49 | 2020-10-26 | 2023-05-18 |
| The Effects of Platelet-Rich Plasma Versus Prolotherapy On Rotator Cuff Tendinopathy: A Randomized Controlled Trial. Platelet-Rich Plasma, Prolotherapy - Rotator Cuff Tendinosis, Supraspinatus Strain | Phase 1 | Completed | University of Malaya | 60 | 2020-02-17 | 2022-11-02 |
| E-CEL UVEC Cells as an Adjunct Cell Therapy for the Arthroscopic Rotator Cuff Repair in Adults E-CEL UVEC - Rotator Cuff Tears, Muscle Atrophy or Weakness | Phase 1 | Active not recruiting | Hospital for Special Surgery, New York | 20 | 2019-11-20 | 2026-08-20 |
| The Effect of Platelet Rich Plasma Injection Combined With Exercise Rehabilitation in Patients With Rotator Cuff Tear Platelet-Rich Plasma, Hyaluronic Acid, Exercise - Rotator Cuff Tear | Phase 1 | Completed | Taipei Veterans General Hospital, Taiwan | 30 | 2014-03-04 | 2018-06-07 |
| Utilization of AMSC to Enhance Rotator Cuff Repair - Safety and Efficacy Suspension of human autologous MSC 3P - Rotator Cuff Tear | Phase 1 / Phase 2 | Terminated | Bioinova, s.r.o. | 9 | 2012-12-12 | 2019-02-15 |
| Platelet Rich Plasma vs. Corticosteroid Injection in the Treatment of Partial Rotator Cuff Tears Platelet Rich Plasma (PRP), Corticosteroid - Rotator Cuff Tear | Phase 1 | Terminated | University of North Carolina, Chapel Hill | 12 | 2012-11-01 | 2017-04-17 |
| Clinical Study on Mesenchymal Stem Cells Used in the Reconstruction Surgery of the Supraspinatus Muscle Lesions mesenchymal stem cells, without mesenchymal stem cells - Rotator Cuff Tear | Phase 1 | Unknown | Hospital Znojmo | 50 | 2012-01-01 | 2017-09-07 |
| Platelet-Rich Plasma Therapy for Shoulder Pain in Persons With Spinal Cord Injury Platelet-rich plasma (PRP) therapy - Shoulder Pain, Rotator Cuff Tendinitis | Phase 1 | Completed | Kessler Foundation | 6 | 2011-05-01 | 2013-01-15 |
| Study Evaluating Safety Of BMP-655/ACS As An Adjuvant Therapy For Rotator Cuff Repair BMP-655/ACS or Standard of Care - Rotator Cuff Tear | Phase 1 | Terminated | Pfizer | 13 | 2010-09-01 | 2012-04-13 |
| A Safety Study Of BMP-655/ACS As An Adjuvant Therapy For Treatment Of Rotator Cuff Tears BMP-655/ACS+Standard of care or Standard of care - Rotator Cuff Tear | Phase 1 | Terminated | Pfizer | 23 | 2010-06-01 | 2013-02-22 |
Asthenia (1) · Motor Activity (1) · Muscular Atrophy (1) · Rotator Cuff Tear Arthropathy (1) · Shoulder Pain (1) · Spinal Cord Injuries (1) · Tendinopathy (1)
Rupture (17) · Shoulder Injuries (17) · Tendon Injuries (17) · Wounds and Injuries (17) · Musculoskeletal Diseases (3) · Joint Diseases (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Arthralgia (1) · Arthritis (1) · Atrophy (1) · Behavior (1) · Central Nervous System Diseases (1)
Standard of Care (3) · Adrenal Cortex Hormones (1) · BPC 157 (1) · Bupivacaine (1) · Cannabidiol (1) · Dexamethasone (1) · Exercise (1) · Hyaluronic Acid (1) · Indocyanine Green (1) · Prolotherapy (1) · Therapeutics (1) · Triamcinolone Acetonide (1) · salicylhydroxamic acid (1)
Pfizer (2) · University of Southern Denmark (2) · Bioinova, s.r.o. (1) · ChitogenX Inc (1) · Hospital Znojmo (1) · Hospital for Special Surgery, New York (1) · Kessler Foundation (1) · NYU Langone Health (1) · Taipei Veterans General Hospital, Taiwan (1) · Tego Science, Inc. (1) · The Methodist Hospital Research Institute (1) · University of Arkansas (1) · University of Malaya (1) · University of Minnesota (1) · University of North Carolina, Chapel Hill (1)
United States (8) · Czechia (1) · Denmark (1) · Germany (1) · Japan (1) · Malaysia (1) · Netherlands (1) · South Korea (1) · Taiwan (1)
Allison Rao (1) · Berkoff David, MD (1) · Brendan C Mackinnon-Patterson, BS, MPH, MD (1) · Joo Han Oh, Ph.D (1) · Kirk Campbell (1) · Lars Frich (1) · Lars H. Frick, Prof. (1) · Patrick McCulloch, MD (1) · Petr Lesny, MD (1) · Samihah A. Karim, MD (1) · Scott Rodeo, MD (1) · Trevor A. Dyson-Hudson, M.D. (1)
PMID 28932752, PMID 22958838, PMID 2323151, PMID 25446135, PMID 26390274, PMID 31000394, PMID 32379581, PMID 3791738, PMID 39427182, PMID 8020238, PMID 9372778