Clomiphene: Clinical Trials

142 trials of Clomiphene, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

82 completed, 34 unknown, 9 withdrawn, 6 terminated. 44 Phase 4, 38 Not applicable, 33 Phase 2, 23 Phase 3, 9 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 444Completed 23, Unknown 12, Withdrawn 3, Recruiting 2, Active not recruiting 1, Enrolling by invitation 1, Not yet recruiting 1, Terminated 1
Not applicable38Completed 22, Unknown 10, Withdrawn 3, Terminated 2, Enrolling by invitation 1
Phase 233Completed 20, Unknown 6, Terminated 3, Recruiting 2, Not yet recruiting 1, Withdrawn 1
Phase 323Completed 15, Unknown 4, Withdrawn 2, Active not recruiting 1, Recruiting 1
Phase 19Completed 6, Unknown 2, Recruiting 1
Early Phase 13Completed 2, Unknown 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
HRT-PC Trial: Hormone Recovery After Treatment for Prostate Cancer Trial. An Open-label Phase II Study of Clomiphene Citrate in Patients With Persistent Hypogonadism After ADT for Treatment of Localized Prostate Cancer
Clomiphene Citrate 25mg - Prostate Cancer
Phase 2Not yet recruitingUniversity of Nebraska832027-01-312026-10-20
Comparative Efficacy of Antioxidants Alone Versus Combined Therapy With SERMs or FSH in Normogonadotropic Idiopathic OAT Patients: A Randomized Controlled Trial
Antioxidants + Clomiphene Citrate, Antioxidants + FSH, Antioxidants Alone - Oligoasthenoteratozoospermia, Male Infertility
Phase 4Not yet recruitingHamad Medical Corporation3602026-10-152026-10-07
Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes
Testosterone Enanthate, Testosterone Cypionate, Testosterone Propionate - Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes
Not applicableEnrolling by invitationEnhanced Emirates Limited602026-03-122026-05-06
Effect Clomiphene vs Clomiphene Along With Pioglitazone on Ovarian Stimulation Rate
Clomiphene Citrate., Pioglitazone (PIO) + Clomiphene citrate - Infertility Treatment, Pregnancy Rates
Phase 4RecruitingPAEC General Hospital, Islamabad622026-03-012026-03-10
Interest of Clomiphene Citrate in Patients With Non-obstructive Azoospermia on the Quantity of Sperm Cells
Clomifene Citrate, Placebo - Azoospermia, Nonobstructive
Phase 3WithdrawnHospices Civils de Lyon2026-01-012026-06-17
Comparison of Clomiphene Alone Versus Clomiphene Plus Sildenafil for Ovulation in Women With Polycystic Ovary Syndrome
Clomiphene Citrate 100 mg, Sildenafil Citrate 25Mg Tab, Placebo - Polycystic Ovarian Syndrome (PCOS), Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Phase 4CompletedNishtar Medical University982025-07-012026-08-18
Evaluation of a Long Versus Short Clomid Protocol for Controlled Ovarian Stimulation
Clomiphene Citrate - Infertility, Female
Phase 4RecruitingUniversity of Southern California1202025-06-012026-08-04
Clomiphene Citrate Alone Versus Clomiphene Plus Metformin as First Line Approach for the Treatment of Anovulation in Infertile Patients With Polycystic Ovary Syndrome
Clomiphane citrate + Metformin, clomiphene citrate alone - Polycystic Ovary Syndrome (PCOS), Anovulatory Infertility
Not applicableCompletedIndependent University Hospital, Pakistan2182025-01-012026-10-13
Study of Tolerability, Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Medicinal Product MediReg®
Medicinal product MediReg® (Human Mesenchymal Stromal Cell Secretome), lyophilizate for preparation of solution for injection in patients with severe spermatogenesis disorders, Clostilbegit (clomiphene) 50 mg 1 tablet x 1 p a day - 3 months, Triovit - 1 tablet x 1 p a day - 3 months, Folic acid - 1 tablet x 1 p a day - 3 months. - Azoospermia, Nonobstructive, Teratospermia
Phase 1 / Phase 2RecruitingLomonosov Moscow State University Medical Research and Educational Center802024-11-262025-03-11
One-shot Ovarian Stimulation Protocol (One-shot)
Corifollitropin alfa (CFA) 150 mcg + Clomiphene Citrate (CC) 100 mg/day from D1, Clomiphene Citrate (CC) 100 mg/day from D1, Monitoring cycle - Infertility, Female
Not applicableCompletedFundación Santiago Dexeus Font202024-10-312026-09-08
Comparison of the Effect of Gonadotropin and Clomiphene Citrate Treatment on Sperm Parameters and the Outcome of Assisted Reproductive Procedures in Subfertile Men Based on the APHRODITE Groups
recFSH, HCG injection, Clomiphene Citrate 50 mg - Male Infertility
Phase 4Enrolling by invitationSzeged University5002024-09-012026-04-16
Comparison of Clomid and Lezra With Lezra for Ovulation Induction in Clomid Resistant PCOS Case
Clomiphene Citrate and letrozole - Polycystic Ovarian Syndrome
Phase 1CompletedHITEC-Institute of Medical Sciences422024-06-072026-05-07
Combination Letrozole and Clomiphene Citrate Versus Letrozole Alone
Letrozole 2.5mg - Polycystic Ovary Syndrome
Not applicableUnknownEgymedicalpedia642024-03-012024-07-18
Cost-effective Treatment of Unexplained Infertility
Clomiphene Citrate., Sildenafil Citrate, Intrauterine Insemination - Unexplained Infertility
Phase 4CompletedBatterjee Medical College9002024-01-012025-02-13
Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome
Myo-Inositol + Levomefolic acid, Clomiphene Citrate, placebo - Polycystic Ovary Syndrome, Reproductive Medicine
Phase 3RecruitingUniversity Hospital, Lille2762023-09-122026-04-22
Use of Clomiphene Citrate as an Inhibitor of Ovulation in an Oocyte Cryopreservation Cycle
Clomiphene - Infertility, Female, Infertility
UnknownNeil Chappell102023-07-012023-05-19
The Effect Of Polycystic Ovarian Syndrome Treatment On Ocular Surface.
dry eye diagnostic system of Mediworks, Optical coherence tomography angiography, Contraceptives, Oral, Combined - Poly Cystic Ovary Syndrome
CompletedCairo University902023-06-242026-02-19
Letrozole vs. Clomiphene Citrate Plus Tamoxifen for Ovulation Induction and Pregnancy Outcomes.
Letrozole, Clomiphene Citrate + Tamoxifen - Infertility Drugs, Infertility Involuntary
Phase 3Active not recruitingSana'a University2402023-05-012026-06-01
Sex Hormone Supplementation and Rotator Cuff Repair: A Preliminary Randomized Trial
Clomiphene Citrate, Rotator Cuff Repair - Rotator Cuff Tears
Phase 2RecruitingUniversity of Utah582023-03-092026-03-19
Comparison of Recombinant Follicle Stimulating Hormone and the Combination of Recombinant Follicle Stimulating Hormone With Clomiphene Citrate in Stimulated Intrauterine Insemination Cycles
Recombinant Follicle Stimulating Hormone, Recombinant Follicle Stimulating Hormone and Clomiphene Citrate - Infertility Unexplained
Not applicableUnknownBezmialem Vakif University2542023-01-012024-02-02

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Conditions studied

Infertility (54)  ·  Polycystic Ovary Syndrome (54)  ·  Anovulation (21)  ·  Infertility, Female (12)  ·  Hypogonadism (6)  ·  Infertility, Male (6)  ·  Azoospermia (3)  ·  Endocrine System Diseases (3)  ·  Insulin Resistance (3)  ·  Vitamin D Deficiency (3)  ·  Azoospermia, Nonobstructive (2)  ·  Endometriosis (2)  ·  Eunuchism (2)  ·  Hyperandrogenism (2)  ·  Hyperinsulinism (2)

Sponsors

Ain Shams University (12)  ·  Cairo University (8)  ·  University Magna Graecia (6)  ·  Assiut University (5)  ·  Mansoura University (4)  ·  Ain Shams Maternity Hospital (3)  ·  Weill Medical College of Cornell University (3)  ·  Yale University (3)  ·  Benha University (2)  ·  Beni-Suef University (2)  ·  Ferring Pharmaceuticals (2)  ·  National Center for Research Resources (NCRR) (2)  ·  Rachel Mejia (2)  ·  University of Athens (2)  ·  University of Illinois at Chicago (2)

Countries

Egypt (40)  ·  United States (30)  ·  Italy (9)  ·  Pakistan (6)  ·  Iran (4)  ·  Belgium (3)  ·  Brazil (3)  ·  Spain (3)  ·  Turkey (Türkiye) (3)  ·  China (2)  ·  France (2)  ·  Russia (2)  ·  Bangladesh (1)  ·  Canada (1)  ·  Germany (1)

Top investigators

Stefano Palomba, MD (6)  ·  Achille Tolino, MD (3)  ·  Ahmed Maged (3)  ·  Francesco Orio, MD (3)  ·  Heping Zhang, PhD (3)  ·  Christos Coutifaris, MD (2)  ·  Esther Eisenberg, MD, MPH (2)  ·  Hatem Abu Hashim, MD. MRCOG (2)  ·  Michael Diamond, MD (2)  ·  Nanette Santoro, MD (2)  ·  Peter Casson, MD (2)  ·  Rachel Mejia, DO (2)  ·  Richard Legro, MD (2)

Results publications

PMID 26354094, PMID 21645894, PMID 25324541, PMID 26413816, PMID 27402910, PMID 29102040, PMID 29778387, PMID 30085176, PMID 33190149, PMID 34180998, PMID 35125179, PMID 39672366, PMID 11597618, PMID 12849816, PMID 14726171, PMID 16291975, PMID 17287476, PMID 17720020, PMID 18000088, PMID 18440534, PMID 18950759, PMID 19114272, PMID 19401323, PMID 19405411, PMID 19509098, PMID 19910321, PMID 20435692, PMID 20826578, PMID 20858697, PMID 21693030, PMID 21770837, PMID 21782166, PMID 21832111, PMID 22431566, PMID 22617579, PMID 22958644, PMID 23249758, PMID 23809505, PMID 24009134, PMID 24156957, PMID 24348019, PMID 24813752, PMID 25006718, PMID 25295506, PMID 25707331, PMID 25788569, PMID 26036903, PMID 26202922, PMID 26235968, PMID 26391671

NIH funding

2009 (1), 2018 (1), R01HD100369 (1), U10HD039005 (1), U10HD055925 (1)