92 completed, 6 terminated, 6 unknown, 3 not yet recruiting. 88 Not applicable, 7 Phase 3, 2 Phase 4, 1 Phase 2.
Follow Refractive Error: new trials by email Literature Review of Refractive Error trials Research Report on Refractive Error
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IOL Power Formula Prediction Accuracy at the Extremes of Axial Length: A Prospective Outcome Verification Study Standardized postoperative outcome visit - Pseudophakia, Refractive Error | Not yet recruiting | Vienna Hospital Association | 200 | 2026-08-01 | 2026-07-24 | |
| Survey of Sensory Impairment Indicators Among Adults Aged 65 Years and Older in Xinxing County Visual Impairment, Hearing Loss | Not yet recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 2854 | 2026-07-06 | 2026-07-10 | |
| Community-Based Eye Screening With Structured Referral Tracking for Preventing Avoidable Blindness in Adults in Rawalpindi, Pakistan Structured Referral Tracking (SRT) - Cataract, Refractive Error | Not applicable | Not yet recruiting | Health Services Academy, Islamabad, Pakistan | 500 | 2026-06-01 | 2026-06-04 |
| Comparison of PRESBYOND Laser Blended Vision and Conventional Monovision LASIK in Individuals With Presbyopia: A Randomized Clinical Study Laser Blended Vision LASIK, Traditional Monovision LASIK - Presbyopia, Refractive Error | Not applicable | Recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 100 | 2026-05-12 | 2026-07-07 |
| An Evaluation of Myopia Control Lenses on Wearing Experience in Myopic Children A.M.L. Series of Lenses - Myopia, Refractive Error | Not applicable | Recruiting | Essilor International | 40 | 2026-01-02 | 2026-01-23 |
| Post Marketing Clinical Study on the Efficacy of Lenses From a New Prescription Protocol AVA lenses, Standard lenses - Ametropia, Refractive Error | Not applicable | Completed | Essilor International | 120 | 2025-09-22 | 2026-06-09 |
| A Non-Treatment Clinical Evaluation of the ELITA Single Piece Patient Interface for Docking Procedure With the ELITA Docking Assessment / Observation - Refractive Error | Completed | Johnson & Johnson Surgical Vision, Inc. | 55 | 2024-12-06 | 2025-12-11 | |
| Frequency of Visual Impairment Among School Children and Effectiveness of mHealth Referral Reminder on Uptake of Referral Services Multicomponent SMS reminder - Visual Impairment, Refractive Error | Not applicable | Completed | Syed Fawad Mashhadi | 320 | 2024-10-21 | 2025-10-07 |
| Clinical Investigation on Assessing the Repeatability and Reproducibility of Central and Peripheral Refractive Error Experimental - Refractive Error | Completed | Johnson & Johnson Vision Care, Inc. | 30 | 2024-01-16 | 2025-04-25 | |
| Phase 3 Efficacy Study of LNZ100 & LNZ101 for the Treatment of Presbyopia Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle - Presbyopia, Near Vision | Phase 3 | Completed | LENZ Therapeutics, Inc | 229 | 2023-03-06 | 2026-10-08 |
| Phase 3 Safety Study of LNZ100 and LNZ101 for the Treatment of Presbyopia Subjects Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle - Presbyopia, Near Vision | Phase 3 | Completed | LENZ Therapeutics, Inc | 362 | 2023-02-21 | 2026-05-13 |
| A PHASED, PROSPECTIVE, MULTI-CENTER STUDY OF THE ELITA SYSTEM ELITA System - Refractive Error | Not applicable | Terminated | Johnson & Johnson Surgical Vision, Inc. | 96 | 2023-02-02 | 2026-03-16 |
| Phase 3 Evaluation of the Safety and Efficacy of LNZ100 & LNZ101 for the Treatment of Presbyopia Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Brimonidine - Presbyopia, Refractive Error | Phase 3 | Completed | LENZ Therapeutics, Inc | 469 | 2022-12-19 | 2026-05-13 |
| Clinical Investigation of Refraction Techniques Refractive Technique (MR #1), Refractive Technique (MR #2) - Refractive Error | Completed | Johnson & Johnson Surgical Vision, Inc. | 35 | 2022-07-14 | 2023-01-06 | |
| A Post-market Clinical Study to Collect Safety and Performance Data on Johnson & Johnson Surgical Vision Products Intervention - Refractive Error, Glaucoma | Completed | Johnson & Johnson Surgical Vision, Inc. | 1674 | 2022-06-21 | 2025-07-20 | |
| Comparison of Anterior Corneal Optical Aberration Induced by CK and Hyperopic LASIK CK surgery - Refractive Error | Unknown | Wang Hongxia | 69 | 2020-12-01 | 2020-12-21 | |
| A Comparative Study of TECNIS Symfony Plus IOL and a Trifocal IOL TECNIS Symfony plus IOL Model ZHR00V, Trifocal Intraocular lens - Cataract, Refractive Error | Not applicable | Completed | Johnson & Johnson Surgical Vision, Inc. | 205 | 2020-01-24 | 2021-08-05 |
| Wavefront-guided LASIK for Monovision Treatment of Myopic Subjects With Presbyopia iDesign Refractive Studio with STAR S4 IR® Excimer laser System - Refractive Error | Not applicable | Completed | AMO Development, LLC | 219 | 2019-09-24 | 2026-07-23 |
| Perfecting Refraction in India With Superior Service Models School Model, Referral Model, Referral Model + Cost Recovery - Refractive Error | Not applicable | Completed | Sun Yat-sen University | 162 | 2019-08-12 | 2024-10-30 |
| Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 1 Verofilcon A contact lenses, Etafilcon A contact lenses - Refractive Error, Myopia | Not applicable | Completed | Alcon Research | 92 | 2019-05-03 | 2020-06-25 |
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Refractive Errors (110) · Myopia (40) · Presbyopia (17) · Astigmatism (13) · Hyperopia (9) · Cataract (7) · Vision Disorders (4) · Eye Diseases (3) · Asthenopia (2) · Amblyopia (1) · Corneal Diseases (1) · Diabetic Retinopathy (1) · Dry Eye Syndromes (1) · Dyslexia (1) · Glaucoma (1)
Eye Diseases (107) · Lens Diseases (7) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Nervous System Diseases (5) · Neurologic Manifestations (5) · Sensation Disorders (5) · Central Nervous System Diseases (2) · Cranial Nerve Diseases (2) · Retinal Diseases (2) · Brain Diseases (1) · Cardiovascular Diseases (1) · Communication Disorders (1) · Diabetes Complications (1) · Diabetes Mellitus (1)
Eyeglasses (3) · Contact Lenses, Hydrophilic (2) · Abortion, Induced (1) · Brimonidine Tartrate (1) · Carboxymethylcellulose Sodium (1) · Cataract Extraction (1) · Contact Lenses (1) · Docosahexaenoic Acids (1) · Ethanol (1) · Keratomileusis, Laser In Situ (1) · Methods (1) · Vision Screening (1)
Alcon Research (44) · Johnson & Johnson Vision Care, Inc. (13) · Johnson & Johnson Surgical Vision, Inc. (6) · CIBA VISION (5) · Alcon, a Novartis Company (3) · Brien Holden Vision (3) · LENZ Therapeutics, Inc (3) · Abbott Medical Optics (2) · Essilor International (2) · Johns Hopkins University (2) · Sun Yat-sen University (2) · University of Alabama at Birmingham (2) · University of California, San Diego (2) · University of Nebraska (2) · Zhongshan Ophthalmic Center, Sun Yat-sen University (2)
United States (34) · United Kingdom (8) · China (6) · Canada (5) · Japan (5) · Australia (4) · Singapore (3) · Austria (2) · Germany (2) · India (2) · Pakistan (2) · Spain (2) · Hong Kong (1) · Iran (1) · Israel (1)
Joachim Nick, Dipl. Ing. (6) · Kris Gambelin, BS (3) · David J Schanzlin, MD (2) · Jessie Lemp, PhD (2) · Jiyoon Chung, BOptom (2) · Kent M. Daum, O.D., Ph.D. (2) · Lisa L. Zoota, MPH, CCRA (2) · Michael Feilmeier, MD (2) · Nicholas Tarantino, OD (2)
PMID 30907859, PMID 14518738, PMID 14709295, PMID 16286622, PMID 16722483, PMID 16850290, PMID 17269242, PMID 17568211, PMID 17998508, PMID 18494342, PMID 18500082, PMID 19537363, PMID 19603619, PMID 26070228, PMID 30451806, PMID 31112777, PMID 35937227, PMID 40980391, PMID 41161831
R01AG015812 (1)