4 completed, 2 unknown, 1 terminated. 7 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 4, Unknown 2, Terminated 1 |
Follow Refractive Error: new trials by email Literature Review of Refractive Error trials Research Report on Refractive Error
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 3 Efficacy Study of LNZ100 & LNZ101 for the Treatment of Presbyopia Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle - Presbyopia, Near Vision | Phase 3 | Completed | LENZ Therapeutics, Inc | 229 | 2023-03-06 | 2026-10-08 |
| Phase 3 Safety Study of LNZ100 and LNZ101 for the Treatment of Presbyopia Subjects Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle - Presbyopia, Near Vision | Phase 3 | Completed | LENZ Therapeutics, Inc | 362 | 2023-02-21 | 2026-05-13 |
| Phase 3 Evaluation of the Safety and Efficacy of LNZ100 & LNZ101 for the Treatment of Presbyopia Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Brimonidine - Presbyopia, Refractive Error | Phase 3 | Completed | LENZ Therapeutics, Inc | 469 | 2022-12-19 | 2026-05-13 |
| Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure Supracor - Myopia, Hyperopia | Phase 3 | Completed | Technolas Perfect Vision GmbH | 61 | 2010-04-01 | 2015-05-20 |
| Randomized Clinical Trial of Bifocal Lenses Versus Computer-specific Progressive Addition Lenses D-28 bifocal lenses and frame, Progressive addition computer lenses and frame - Refractive Error, Presbyopia | Phase 3 | Terminated | University of Alabama at Birmingham | 40 | 2006-10-01 | 2011-06-15 |
| Effects of Optical Blur on Performance and Comfort of Computer Users Eyeglass lenses - Refractive Error | Phase 3 | Unknown | Vision Council of America | 35 | 2005-10-01 | 2006-04-25 |
| Vision In Preschoolers Study (VIP Study) Vision Screening - Amblyopia, Strabismus | Phase 3 | Unknown | National Eye Institute (NEI) | 2009-10-16 |
Refractive Errors (7) · Presbyopia (5) · Myopia (4) · Eye Diseases (3) · Asthenopia (2) · Amblyopia (1) · Hyperopia (1) · Strabismus (1)
Eye Diseases (4) · Brain Diseases (1) · Central Nervous System Diseases (1) · Cranial Nerve Diseases (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Ocular Motility Disorders (1) · Pathological Conditions, Signs and Symptoms (1) · Sensation Disorders (1) · Signs and Symptoms (1) · Vision Disorders (1)
Brimonidine Tartrate (1) · Keratomileusis, Laser In Situ (1) · Vision Screening (1)
LENZ Therapeutics, Inc (3) · National Eye Institute (NEI) (1) · Technolas Perfect Vision GmbH (1) · University of Alabama at Birmingham (1) · Vision Council of America (1)
United States (6) · Mexico (1)
Kris Gambelin, BS (3) · Kent M. Daum, O.D., Ph.D. (2) · Enrique Barragan, M.D. (1)
PMID 16722483, PMID 16850290, PMID 17269242, PMID 18494342, PMID 18500082, PMID 19537363, PMID 19603619