1218 completed, 282 unknown, 142 recruiting, 103 not yet recruiting. 1302 Not applicable, 85 Phase 3, 76 Phase 4, 63 Phase 2, 44 Phase 1.
Follow Refractive Errors: new trials by email Literature Review of Refractive Errors trials Research Report on Refractive Errors
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Emmetropization Via Accommodation (EVA) - II Study Experimental treatment arm - Hyperopia, Farsightedness | Not applicable | Not yet recruiting | Ohio State University | 52 | 2027-04-01 | 2026-09-24 |
| Eye Health Intervention Study in Upper Manhattan Intervention, Usual Care - Glaucoma, Suspect, Diabetic Retinopathy | Not applicable | Withdrawn | Columbia University | 2027-04-01 | 2026-05-29 | |
| Retinopathy of Prematurity - Visual Function and Retinal Structure Retinopathy of Prematurity (ROP), Prematurity Complications | Not yet recruiting | Oslo University Hospital | 140 | 2027-01-01 | 2026-11-10 | |
| Using Contact Lenses and Spectacle Lenses as Myopia Interventions. Test Spectacle Lens & Contact Lens, Control Spectacle Lens & Contact Lens - Myopia | Not applicable | Not yet recruiting | CooperVision International Limited (CVIL) | 58 | 2026-12-01 | 2026-11-03 |
| The EYERISING Study Repeated Low-Level Red Light (RLRL) therapy, Placebo Device - Myopia, Astigmatism | Not applicable | Not yet recruiting | University of Wisconsin, Madison | 333 | 2026-12-01 | 2026-11-05 |
| BRIGHT-LIGHT: Studying Red Light Therapy for Severe Short-Sightedness or Short-Sightedness That Worsens Despite Standard Treatment Repeated low-level red-light (RLRL) therapy, Continued existing myopia treatment strategy - Myopia, Myopia Progressing | Not applicable | Not yet recruiting | Singapore National Eye Centre | 40 | 2026-12-01 | 2026-11-06 |
| Evaluation of Two Monthly Silicone Hydrogel Multifocal Toric in Soft Contact Lens Wearers Lens A ( comfilcon A), Lens B ( lehfilcon A) - Astigmatism, Myopia | Not applicable | Recruiting | CooperVision International Limited (CVIL) | 60 | 2026-11-02 | 2026-11-04 |
| Evaluation of the Agreement Between Automated Program-Operated Phoropter Subjective Refraction and Optometrist-Performed Subjective Refraction Automated Program-Controlled Subjective Refraction, Optometrist-Performed Subjective Refraction - Refractive Errors | Not applicable | Not yet recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 508 | 2026-11-01 | 2026-10-23 |
| Consistency of an Automated Subjective Refraction Program Between Personnel With Diverse Professional Backgrounds and Senior Optometrists Nurse-Operated Automated Subjective Refraction, Village Doctor-Operated Automated Subjective Refraction, Lay Personnel-Operated Automated Subjective Refraction - Refractive Errors | Not applicable | Not yet recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 254 | 2026-11-01 | 2026-10-23 |
| Study of an Implantable Collamer Lens (ICL) Implantable collamer lens (ICL) - Myopia, Astigmatism | Not applicable | Not yet recruiting | Staar Surgical Company | 10 | 2026-11-01 | 2026-08-27 |
| Efficacy of Myopia-control Lenses in a Population of Young Adults : the OPTIMA Study Essilor® Stellest® 2.0 myopia-slowing lenses, Standard lenses - Myopia | Not applicable | Not yet recruiting | Fondation Ophtalmologique Adolphe de Rothschild | 134 | 2026-11-01 | 2026-09-04 |
| Attention-based Binocular Training for Impaired Stereopsis (BRAVE) Attention-Guided Dichoptic Visual Search Training, Zero-Disparity Dichoptic Visual Search Task - Amblyopia, Strabismus | Not applicable | Not yet recruiting | Centre for Eye and Vision Research | 56 | 2026-11-01 | 2026-09-03 |
| Study of a Phakic Implantable Collamer Lens (ICL) Phakic Implantable Collamer Lens (ICL) - Myopia, Astigmatism | Not applicable | Not yet recruiting | Staar Surgical Company | 10 | 2026-11-01 | 2026-08-27 |
| Clinical Performance and Outcomes After Toric Lens Transition Fanfilcon A Toric Contact Lens - Astigmatism | Not applicable | Not yet recruiting | CooperVision International Limited (CVIL) | 35 | 2026-11-01 | 2026-11-05 |
| Psilocybin for Amblyopia - Targeting Critical Periods in Humans Amblyopia Therapy, 1 mg Psilocybin, 5 mg Psilocybin - Amblyopia | Phase 1 / Phase 2 | Recruiting | Johns Hopkins University | 24 | 2026-11-01 | 2026-11-05 |
| Prevalence of Presbyopia (Near Vision Fatigue) and Related Factors Among Working Adults Aged 30 to 55 Years in Shanghai Presbyopia | Not yet recruiting | Shanghai Eye Disease Prevention and Treatment Center | 1366 | 2026-11-01 | 2026-11-09 | |
| Efficacy and Safety of Spectacle Lenses With H.A.L.T. MAX Technology on High Myopia Control in Children and Adolescents H.A.L.T. MAX spectacles - Myopia, High Myopia | Not applicable | Withdrawn | Shanghai Eye Disease Prevention and Treatment Center | 2026-10-30 | 2026-11-02 | |
| Corneal Biomechanics and Stromal Tissue Characteristics in Patients Undergoing SMILE SMILE - Myopia | Not yet recruiting | Tongji University | 200 | 2026-10-25 | 2026-11-04 | |
| Early Intervention for High Risk Premyopic Children 0.025% atropine eye drops, DIMS TED - Myopia | Phase 2 | Not yet recruiting | National Yang Ming Chiao Tung University Hospital | 240 | 2026-10-24 | 2026-10-07 |
| Dual-Action Lenses for Slowing Myopia in Children and Teens: A Randomized, Double-Blind Trial Dual-Action Myopia-Control Spectacle Lens, Stellest Myopia-Control Spectacle Lens（Highly Aspherical Lenslet Target / HALT Lens） - Myopia, Refractive Errors | Not applicable | Not yet recruiting | Shanghai Eye Disease Prevention and Treatment Center | 120 | 2026-10-05 | 2026-10-02 |
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Myopia (1090) · Astigmatism (405) · Presbyopia (334) · Cataract (201) · Hyperopia (155) · Myopia, Degenerative (69) · Amblyopia (33) · Anisometropia (30) · Eye Diseases (30) · Vision Disorders (29) · Aphakia (21) · Glaucoma (20) · Pseudophakia (19) · Corneal Diseases (18)
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PMID 36809645, PMID 26875007, PMID 17269242, PMID 19537363, PMID 19603619, PMID 31142465, PMID 33102611, PMID 15875367, PMID 18494342, PMID 19416935, PMID 22559900, PMID 22729437, PMID 23109740, PMID 26903524, PMID 27767354, PMID 27893063, PMID 27893066, PMID 30907859, PMID 34866900, PMID 35749069, PMID 37369096, PMID 38216351, PMID 39384223, PMID 40306584, PMID 40782835, PMID 41171741, PMID 10048351, PMID 10343811, PMID 10504084, PMID 10764848, PMID 10764849, PMID 10764850, PMID 10764851, PMID 11316705, PMID 11807381, PMID 11874738, PMID 12532491, PMID 12535999, PMID 12657584, PMID 12714612, PMID 12809158, PMID 12809160, PMID 12939289, PMID 12939339, PMID 14518738, PMID 14640432, PMID 14709295, PMID 14985292, PMID 15078666, PMID 15093657
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