1209 completed, 284 unknown, 141 recruiting, 104 not yet recruiting. 1296 Not applicable, 85 Phase 3, 76 Phase 4, 62 Phase 2, 43 Phase 1.
Follow this condition Literature Review of Refractive Errors trials Research Report on Refractive Errors
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Emmetropization Via Accommodation (EVA) - II Study Experimental treatment arm - Hyperopia, Farsightedness | Not applicable | Not yet recruiting | Ohio State University | 52 | 2027-04-01 | 2026-09-24 |
| Eye Health Intervention Study in Upper Manhattan Intervention, Usual Care - Glaucoma, Suspect, Diabetic Retinopathy | Not applicable | Withdrawn | Columbia University | 2027-04-01 | 2026-05-29 | |
| Study of an Implantable Collamer Lens (ICL) Implantable collamer lens (ICL) - Myopia, Astigmatism | Not applicable | Not yet recruiting | Staar Surgical Company | 10 | 2026-11-01 | 2026-08-27 |
| Efficacy of Myopia-control Lenses in a Population of Young Adults : the OPTIMA Study Essilor® Stellest® 2.0 myopia-slowing lenses, Standard lenses - Myopia | Not applicable | Not yet recruiting | Fondation Ophtalmologique Adolphe de Rothschild | 134 | 2026-11-01 | 2026-09-04 |
| Attention-based Binocular Training for Impaired Stereopsis (BRAVE) Attention-Guided Dichoptic Visual Search Training, Zero-Disparity Dichoptic Visual Search Task - Amblyopia, Strabismus | Not applicable | Not yet recruiting | Centre for Eye and Vision Research | 56 | 2026-11-01 | 2026-09-03 |
| Study of a Phakic Implantable Collamer Lens (ICL) Phakic Implantable Collamer Lens (ICL) - Myopia, Astigmatism | Not applicable | Not yet recruiting | Staar Surgical Company | 10 | 2026-11-01 | 2026-08-27 |
| Early Intervention for High Risk Premyopic Children 0.025% atropine eye drops, DIMS TED - Myopia | Phase 2 | Not yet recruiting | National Yang Ming Chiao Tung University Hospital | 240 | 2026-10-24 | 2026-10-07 |
| Dual-Action Lenses for Slowing Myopia in Children and Teens: A Randomized, Double-Blind Trial Dual-Action Myopia-Control Spectacle Lens, Stellest Myopia-Control Spectacle Lens（Highly Aspherical Lenslet Target / HALT Lens） - Myopia, Refractive Errors | Not applicable | Not yet recruiting | Shanghai Eye Disease Prevention and Treatment Center | 120 | 2026-10-05 | 2026-10-02 |
| Study of Eye Fatigue From Digital Screens and Its Impact on Visual Performance in People With Normal Vision and Myopia, With and Without Dry Eye Symptoms and Signs Eye Exams, Ocular Biometry and Aberrometry, Wearing a Smartwatch - Myopia, Dry Eye Disease (DED) | Not applicable | Not yet recruiting | Essilor International | 120 | 2026-10-01 | 2026-09-28 |
| Comparing Myopia Control Spectacle Lenses and Standard Single Vision Spectacle Lenses in Children With Myopia Investigational Myopia Control Spectacle Lens, Single Vision Spectacle Lens - Myopia, Myopia Progression | Not applicable | Not yet recruiting | Essilor International | 20 | 2026-10-01 | 2026-09-24 |
| Comparison of Hand Eye Coordination and Sports Vision Performance in Dual-Focus Multifocal Contact Lenses and Habitual Contact Lenses Multifocal Contact Lens - Myopia | Not applicable | Recruiting | Ohio State University | 20 | 2026-10-01 | 2026-09-24 |
| Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-Match TECNIS PureSee IOL (Model DEN00V/DET150), TECNIS Odyssey IOL (Model DRN00V/DRT150) - Presbyopia Correction, Presbyopia | Phase 4 | Not yet recruiting | Dr. Daniel H. Chang, MD | 68 | 2026-10-01 | 2026-10-06 |
| Control of Myopia in Young Children Using H.O.P.E. Lenses Combined With 0.02% Atropine Eye Drops High-order Phase Element Array Microstructure Design Lens (H.O.P.E.), 0.02% Atropine Sulfate Eye Drops - Myopia | Not applicable | Not yet recruiting | Ruihua Wei | 264 | 2026-09-30 | 2026-09-29 |
| Proof-of-Concept for a Novel Optical Aperture Contact Lens in Presbyopia and Keratoconus NOA lens type 1, NOA lens type 2 - Keratoconus, Presbyopia | Not applicable | Recruiting | Azalea Vision | 16 | 2026-09-28 | 2026-10-13 |
| Evaluation of Functional Superiority of the Morrow eProgressive 3 weeks wearing of study device instead of their current wearing solution - Presbyopia | Not applicable | Recruiting | Morrow Eyewear | 50 | 2026-09-24 | 2026-10-16 |
| Children Receiving Monocular MiSight® 1 Day Treatment for Unilateral Myopia MiSight® 1 Day - Myopia (Disorder), Anisometropia | Not yet recruiting | Buddhist Tzu Chi General Hospital | 100 | 2026-09-15 | 2026-08-21 | |
| Can Tailored Surgical Incisions Reduce Refractive Error and Dependence on Glasses After Cataract Surgery? Adapted clear corneal incisions - Cataract (Post-operative Cataract Surgery Follow-up), Refraction Error | Not applicable | Not yet recruiting | Linkoeping University | 100 | 2026-09-15 | 2026-06-03 |
| Managing Premyopia in Chinese Children Using Artificial Intelligence Assisted Defocus Incorporated Multiple Segments Based Spectacle Lens: a Randomized Controlled Clinical Trial Artificial Intelligence Assisted DIMS based Spectacle Lens, Smartwatches - Pre-myopia, Myopia | Not applicable | Not yet recruiting | Shanghai Eye Disease Prevention and Treatment Center | 128 | 2026-09-12 | 2026-08-18 |
| Screening for Hyperopic Reserve in Kindergarten Myopia | Recruiting | Beijing Tongren Hospital | 134000 | 2026-09-01 | 2026-10-01 | |
| Contact Lenses to Slow Myopia Progression in Adults Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens - Myopia, Myopia Progression | Not applicable | Not yet recruiting | University of California, Berkeley | 152 | 2026-09-01 | 2026-08-05 |
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Myopia (1085) · Astigmatism (402) · Presbyopia (333) · Cataract (201) · Hyperopia (155) · Myopia, Degenerative (69) · Amblyopia (32) · Eye Diseases (30) · Vision Disorders (29) · Anisometropia (28) · Aphakia (21) · Glaucoma (20) · Pseudophakia (19) · Corneal Diseases (18)
Eye Diseases (1903) · Lens Diseases (206) · Pathological Conditions, Signs and Symptoms (117) · Signs and Symptoms (96) · Nervous System Diseases (82) · Neurologic Manifestations (73) · Sensation Disorders (65) · Myopia (43) · Central Nervous System Diseases (37) · Vision Disorders (36) · Brain Diseases (35) · Retinal Diseases (32) · Behavior (31) · Corneal Diseases (21)
Atropine (44) · Eyeglasses (43) · Keratomileusis, Laser In Situ (40) · Cataract Extraction (35) · Contact Lenses (23) · Contact Lenses, Hydrophilic (21) · Ophthalmic Solutions (17) · Photorefractive Keratectomy (14) · Phacoemulsification (13) · Brimonidine Tartrate (12) · Pilocarpine (10) · Control Groups (9) · Therapeutics (9) · Ranibizumab (7) · Low-Level Light Therapy (6)
Alcon Research (174) · CooperVision, Inc. (150) · Johnson & Johnson Vision Care, Inc. (78) · Bausch & Lomb Incorporated (57) · CIBA VISION (48) · Shanghai Eye Disease Prevention and Treatment Center (42) · The Hong Kong Polytechnic University (38) · Zhongshan Ophthalmic Center, Sun Yat-sen University (36) · Tianjin Eye Hospital (31) · Essilor International (29) · Democritus University of Thrace (26) · Sun Yat-sen University (22) · Ohio State University (21) · CooperVision International Limited (CVIL) (20) · Beaver-Visitec International, Inc. (18)
United States (624) · China (260) · United Kingdom (104) · Canada (96) · Spain (52) · France (51) · Singapore (50) · Germany (44) · Taiwan (40) · Egypt (39) · Hong Kong (34) · South Korea (34) · Australia (30) · Austria (28) · Mexico (28)
Georgios Labiris, MD, PhD (16) · Lyndon Jones, PhD FCOptom (9) · Edward E Manche, MD (8) · Lyndon Jones, PhD, FCOptom (8) · Pauline Cho, PhD (8) · Lyndon Jones (7) · Edward E. Manche (6) · Joachim Nick, Dipl. Ing. (6)
PMID 36809645, PMID 26875007, PMID 17269242, PMID 19537363, PMID 19603619, PMID 31142465, PMID 33102611, PMID 15875367, PMID 18494342, PMID 19416935, PMID 22559900, PMID 22729437, PMID 23109740, PMID 26903524, PMID 27767354, PMID 27893063, PMID 27893066, PMID 30907859, PMID 34866900, PMID 35749069, PMID 37369096, PMID 38216351, PMID 39384223, PMID 40306584, PMID 40782835, PMID 41171741, PMID 10048351, PMID 10343811, PMID 10504084, PMID 10764848, PMID 10764849, PMID 10764850, PMID 10764851, PMID 11316705, PMID 11807381, PMID 11874738, PMID 12532491, PMID 12535999, PMID 12657584, PMID 12714612, PMID 12809158, PMID 12809160, PMID 12939289, PMID 12939339, PMID 14518738, PMID 14640432, PMID 14709295, PMID 14985292, PMID 15078666, PMID 15093657
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