229 completed, 40 unknown, 18 recruiting, 16 terminated. 211 Not applicable, 30 Phase 3, 20 Phase 2, 14 Phase 4, 7 Phase 1.
Follow this condition Literature Review of Presbyopia trials Research Report on Presbyopia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-Match TECNIS PureSee IOL (Model DEN00V/DET150), TECNIS Odyssey IOL (Model DRN00V/DRT150) - Presbyopia Correction, Presbyopia | Phase 4 | Not yet recruiting | Dr. Daniel H. Chang, MD | 68 | 2026-10-01 | 2026-10-06 |
| Proof-of-Concept for a Novel Optical Aperture Contact Lens in Presbyopia and Keratoconus NOA lens type 1, NOA lens type 2 - Keratoconus, Presbyopia | Not applicable | Recruiting | Azalea Vision | 16 | 2026-09-28 | 2026-10-13 |
| Evaluation of Functional Superiority of the Morrow eProgressive 3 weeks wearing of study device instead of their current wearing solution - Presbyopia | Not applicable | Recruiting | Morrow Eyewear | 50 | 2026-09-24 | 2026-10-16 |
| Volumetric Visual Fields at Different Distances in Presbyopic Patients Using Occupational (PC-133 and PC-200) and General-Purpose Progressive Addition Lenses OPAL PC 133 assessment, OPAL PC 200 assessment, PAL assessment - Presbyopia | Not applicable | Recruiting | University of Seville | 28 | 2026-06-08 | 2026-10-15 |
| VisDura VisAbility™ Micro Insert System Pre-market Clinical Trial VisAbility™ Micro Insert System - Presbyopia | Not applicable | Recruiting | VisDura, Inc. | 33 | 2026-06-02 | 2026-10-15 |
| Contact Lens Trial Fitting Experience Lens A ( stenfilcon A ) - Presbyopia | Not applicable | Not yet recruiting | CooperVision International Limited (CVIL) | 25 | 2026-05-31 | 2026-05-22 |
| Refitting Satisfied INFUSE One-Day Multifocal Wearers to DAILIES TOTAL1 Multifocal Contact Lenses DAILIES TOTAL1 Multifocal (delefilcon A) - Contact Lens Comfort and Successful Refitting, Presbyopia | Not applicable | Recruiting | Gordon Schanzlin New Vision | 30 | 2026-05-20 | 2026-06-11 |
| Comparison of PRESBYOND Laser Blended Vision and Conventional Monovision LASIK in Individuals With Presbyopia: A Randomized Clinical Study Laser Blended Vision LASIK, Traditional Monovision LASIK - Presbyopia, Refractive Error | Not applicable | Recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 100 | 2026-05-12 | 2026-07-07 |
| Contralateral Claims Study of Clareon Vivity Pro Clareon Vivity Pro IOL, Clareon Vivity IOL, TECNIS PureSee IOL - Aphakia, Presbyopia | Not applicable | Active not recruiting | Alcon Research | 165 | 2026-04-28 | 2026-10-13 |
| Clinical Performance of Verofilcon A Toric Contact Lenses Total 30 multi foric contact lenses - Contact Lenses, Presbyopia | Not applicable | Recruiting | Southern College of Optometry | 32 | 2026-04-01 | 2026-05-14 |
| Performance of Two Daily Disposable Multifocal Contact Lenses Lens A (kalfilcon A), Lens B (stenfilcon A) - Presbyopia | Not applicable | Recruiting | CooperVision International Limited (CVIL) | 35 | 2026-02-24 | 2026-04-08 |
| Comfort and Vision With TOTAL30 Multifocal Lenses TOTAL30 Multifocal - Myopia, Presbyopia | Completed | Scripps Poway Eyecare and Optometry | 32 | 2026-02-05 | 2026-09-04 | |
| Presbyopic Wear Experience With Multifocal Lenses Compared to Single Vision Lenses and Reading Glasses Multifocal contact lenses, Spherical contact lenses - Presbyopia Correction, Presbyopia | Not applicable | Active not recruiting | Ohio State University | 30 | 2025-12-08 | 2026-09-24 |
| Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections With EDOF IOLs Phacoemulsification with EDOF IOLs - Presbyopia | Recruiting | Democritus University of Thrace | 100 | 2025-10-15 | 2026-02-24 | |
| Post Market Clinical Evaluation of Clareon PanOptix Pro and Clareon PanOptix Pro Toric IOLs Clareon PanOptix Pro/Pro Toric Trifocal IOL, Phacoemulsification - Aphakia, Presbyopia | Not applicable | Completed | Alcon Research | 110 | 2025-10-14 | 2026-10-19 |
| Open Label, Multi-center, Phase I Study of TECLens Quantitative Refractive Crosslinking in Presbyopia-Aged Patients. Quantitative refractive crosslinking - Presbyopia | Not applicable | Not yet recruiting | TECLens, Inc. | 25 | 2025-09-30 | 2025-10-06 |
| Volumetric Visual Fields at Intermediate and Near Distances in Presbyopic Patients Using Occupational and General-Purpose Progressive Addition Lenses OPAL PC assesment, OPAL Office assessment, PAL assesment - Presbyopia | Not applicable | Recruiting | University of Seville | 26 | 2025-09-29 | 2026-10-15 |
| The Development of New Functions of Esculin and Digitalis Glycosides Eye Drops: A Study on the Treatment of Presbyopia Esculin and Digitalisglycosides Eye Drops, Normal saline solution - Presbyopia | Phase 4 | Completed | Shanxi Eye Hospital | 62 | 2025-09-04 | 2026-03-25 |
| Quantitative Refractive Crosslinking in Presbyopia Aged Patients Quantitative refractive crosslinking - Presbyopia | Not applicable | Not yet recruiting | TECLens, Inc. | 25 | 2025-08-31 | 2025-08-29 |
| Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic cataract surgery, implantation of device IOL FG-80030.1 - Intraocular Lens, Cataract | Not applicable | Recruiting | Z Optics, Inc. | 60 | 2025-08-07 | 2026-09-18 |
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Cataract (78) · Myopia (53) · Refractive Errors (43) · Astigmatism (28) · Hyperopia (28) · Aphakia (13) · Pseudophakia (9) · Eye Diseases (7) · Asthenopia (4) · Glaucoma (3) · Patient Satisfaction (3) · Vision, Low (3) · Diabetic Retinopathy (2) · Dry Eye Syndromes (2)
Eye Diseases (326) · Refractive Errors (290) · Lens Diseases (80) · Pathological Conditions, Signs and Symptoms (15) · Signs and Symptoms (15) · Nervous System Diseases (8) · Neurologic Manifestations (6) · Sensation Disorders (5) · Behavior (4) · Health Behavior (3) · Lacrimal Apparatus Diseases (3) · Ocular Hypertension (3) · Treatment Adherence and Compliance (3) · Vision Disorders (3) · Cardiovascular Diseases (2)
Cataract Extraction (16) · Brimonidine Tartrate (12) · Pilocarpine (9) · Macrophage Colony-Stimulating Factor (6) · Phacoemulsification (6) · aceclidine (5) · Control Groups (4) · Eyeglasses (4) · Carbachol (3) · Contact Lenses (3) · Keratomileusis, Laser In Situ (3) · Lenses, Intraocular (3) · Mitomycin (3) · Oxymetazoline (3) · Contrast Sensitivity (2)
Alcon Research (36) · Democritus University of Thrace (20) · CooperVision, Inc. (16) · AcuFocus, Inc. (11) · Beaver-Visitec International, Inc. (10) · CIBA VISION (9) · Johnson & Johnson Vision Care, Inc. (9) · Technolas Perfect Vision GmbH (9) · LENZ Therapeutics, Inc (8) · Allergan (7) · Bausch & Lomb Incorporated (6) · CooperVision International Limited (CVIL) (6) · Orasis Pharmaceuticals Ltd. (6) · ACE Vision Group, Inc. (4) · VisDura, Inc. (4)
United States (131) · Greece (20) · United Kingdom (16) · Spain (15) · China (13) · Canada (12) · Philippines (12) · Germany (11) · Australia (10) · France (10) · South Korea (10) · Belgium (7) · Czechia (6) · Japan (6) · Mexico (6)
Georgios Labiris, MD, PhD (13) · Andrew Sacco (3) · Katherine Bickle (3) · Kris Gambelin, BS (3) · Nathan G Congdon, MD, MPH (3) · Perry Binder, MD (3) · Robert Edward Ang, MD (3) · Tae-Young Chung, PhD (3) · Alisyn Facemire, BA (2) · Cesar Alejandro S Galeana, MD (2)
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U01EB023048 (1)