270 completed, 60 unknown, 29 recruiting, 11 terminated. 287 Not applicable, 18 Phase 4, 6 Phase 3, 4 Phase 1, 4 Phase 2.
Follow Astigmatism: new trials by email Literature Review of Astigmatism trials Research Report on Astigmatism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of an Implantable Collamer Lens (ICL) Implantable collamer lens (ICL) - Myopia, Astigmatism | Not applicable | Not yet recruiting | Staar Surgical Company | 10 | 2026-11-01 | 2026-08-27 |
| Study of a Phakic Implantable Collamer Lens (ICL) Phakic Implantable Collamer Lens (ICL) - Myopia, Astigmatism | Not applicable | Not yet recruiting | Staar Surgical Company | 10 | 2026-11-01 | 2026-08-27 |
| Evaluation of Two Monthly Silicone Hydrogel Multifocal Toric in Soft Contact Lens Wearers Lens A ( comfilcon A), Lens B ( lehfilcon A) - Astigmatism, Myopia | Not applicable | Not yet recruiting | CooperVision International Limited (CVIL) | 60 | 2026-09-01 | 2026-09-21 |
| Effect of a Myopia Control Lens on the Astigmatism in Children Lenslet-based myopia control spectacle lens - Astigmatism, Myopia | Not applicable | Not yet recruiting | Essilor International | 15 | 2026-09-01 | 2026-09-15 |
| Evaluation of Orthokeratology Lenses With a 5MM Optic Zone Diameter Lens A (paflufocon D) - Myopia, Astigmatism | Not applicable | Recruiting | CooperVision International Limited (CVIL) | 70 | 2026-08-14 | 2026-10-22 |
| SMILE Surgery in One Eye Compared to Ray Tracing-guided LASIK Surgery in the Fellow Eye Ray tracing guided LASIK surgery - Myopia, Astigmatism | Phase 4 | Recruiting | Stanford University | 62 | 2026-08-05 | 2026-08-26 |
| Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation Syndrome phacoemulsification cataract surgery - Pseudoexfoliation Syndrome, Cataract | Recruiting | Kata Culina | 70 | 2026-07-20 | 2026-08-18 | |
| Corneal Epithelial Thickness Mapping by Anterior Segment Optical Coherence Tomography in Patients With Refractive Errors Myopia, Hyperopia | Not yet recruiting | Sohag University | 360 | 2026-07-01 | 2026-06-15 | |
| Effect of WRAD Lens on Axial Growth and Refraction in Low-hyperopic Chinese Children With-the-Rule Astigmatic Defocus Lens, With-the-Rule Astigmatic Defocus Lens (Non-plano), Single Vision - Hyperopic Astigmatism | Not applicable | Not yet recruiting | He Eye Hospital | 117 | 2026-07-01 | 2026-07-06 |
| Clareon TruPlus Study Clareon TruPlus Monofocal Non-Toric IOL, Clareon TruPlus Monofocal Toric IOL, Phacoemulsification - Aphakia, Astigmatism | Not applicable | Recruiting | Alcon Research | 122 | 2026-05-26 | 2026-06-03 |
| Optimization for Toric Contact Lenses Lens 1 ( stenfilcon A ), Lens 2 ( comfilcon A ) - Astigmatism, Ametropia | Not applicable | Completed | CooperVision International Limited (CVIL) | 29 | 2026-05-15 | 2026-10-23 |
| Rotational Stability of Two Soft Toric Contact Lens Designs Acuvue Oasys for Astigmatism, Air Optix for Astigmatism - Astigmatism | Not applicable | Completed | Bozok University | 40 | 2026-05-02 | 2026-09-01 |
| Evaluation of Mesopic Visual Acuity and Patient Satisfaction Following Ray-Tracing-Guided LASIK Wavelight Plus - Astigmatism, Myopia | Phase 4 | Recruiting | Vance Thompson Vision | 50 | 2026-04-20 | 2026-08-27 |
| Influence of Implantation Technique on Rotational Stability of a Frosted-Haptic Toric Intraocular Lens: A Prospective Contralateral-Eye Study OVD-assisted Implantation, BSS-assisted hydroimplantation - Cataract With Pre-existing Regular Corneal Astigmatism | Not applicable | Active not recruiting | Ain Shams University | 80 | 2026-04-10 | 2026-08-17 |
| A Study to Investigate the Safety and Effectiveness of the Technolas® TENEO 317 Model 2 Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Myopia or Myopic Astigmatism TENEO 317 Model 2 (1.28 US) Excimer Laser - Myopic Astigmatism | Not applicable | Not yet recruiting | Bausch & Lomb Incorporated | 32 | 2026-04-01 | 2026-01-30 |
| Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day Daily disposable contact lenses for astigmatism - Astigmatism | Not applicable | Recruiting | Ohio State University | 40 | 2026-03-04 | 2026-09-25 |
| Revive Toric RWE Study REVIVE samfilcon B custom toric contact lenses - Astigmatism | Withdrawn | Bausch & Lomb Incorporated | 2026-03-01 | 2026-10-16 | ||
| Comfort and Vision With TOTAL30 Multifocal Lenses TOTAL30 Multifocal - Myopia, Presbyopia | Completed | Scripps Poway Eyecare and Optometry | 32 | 2026-02-05 | 2026-09-04 | |
| Improving Visual Quality in Patients With Irregular Corneas Using Asymmetrical Toric Intraocular Lenses AMILens Individual - Irregular Astigmatism, Astigmatism | Not applicable | Recruiting | Johannes Kepler University of Linz | 15 | 2026-01-20 | 2026-01-26 |
| Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery LASIK - Myopia, Astigmatism | Not applicable | Recruiting | Stanford University | 70 | 2026-01-20 | 2026-01-22 |
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Myopia (150) · Cataract (93) · Refractive Errors (50) · Hyperopia (49) · Presbyopia (28) · Aphakia (11) · Corneal Diseases (7) · Dry Eye Syndromes (4) · Glaucoma (4) · Keratoconus (4) · Dilatation, Pathologic (3) · Orientation, Spatial (3) · Patient Satisfaction (3) · Personal Satisfaction (3)
Eye Diseases (401) · Refractive Errors (352) · Lens Diseases (98) · Pathological Conditions, Signs and Symptoms (10) · Behavior (9) · Signs and Symptoms (7) · Corneal Diseases (5) · Lacrimal Apparatus Diseases (5) · Neoplasms (5) · Neoplasms by Histologic Type (5) · Ocular Hypertension (5) · Hemic and Lymphatic Diseases (4) · Immune System Diseases (4) · Immunoproliferative Disorders (4) · Lymphatic Diseases (4)
Keratomileusis, Laser In Situ (19) · Cataract Extraction (15) · Photorefractive Keratectomy (6) · Eyeglasses (5) · Contact Lenses (4) · Corneal Topography (4) · Phacoemulsification (4) · Lasers, Excimer (3) · Dexamethasone (2) · Hyaluronic Acid (2) · Lens Implantation, Intraocular (2) · Levofloxacin (2) · Refractive Surgical Procedures (2) · Tobramycin (2) · Tobramycin, Dexamethasone Drug Combination (2)
Alcon Research (51) · CooperVision, Inc. (33) · Bausch & Lomb Incorporated (19) · Johnson & Johnson Vision Care, Inc. (16) · Beaver-Visitec International, Inc. (8) · Stanford University (8) · Abbott Medical Optics (7) · CooperVision International Limited (CVIL) (7) · Wenzhou Medical University (7) · CIBA VISION (6) · Johnson & Johnson Surgical Vision, Inc. (6) · Staar Surgical Company (6) · Assiut University (5) · Prim. Prof. Dr. Oliver Findl, MBA (5) · Tianjin Eye Hospital (5)
United States (154) · China (29) · United Kingdom (21) · Spain (16) · Canada (15) · Germany (13) · Austria (12) · Mexico (10) · Egypt (9) · France (8) · Japan (7) · India (6) · Australia (5) · South Korea (5) · Taiwan (4)
Edward E Manche, MD (4) · Edward E. Manche (4) · Joanne Egamino, PhD (4) · Kerry D. Solomon, MD (3) · Mark Packer, MD (3) · Oliver Findl, MD, MBA (3) · AYong Yu, MD.PhD. (2) · Anya Loncaric (2) · Charisma B Evangelista, MD (2) · Clayton G Blehm, MD (2)
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R01EY018184 (1), UG1EY029657 (1)