220 completed, 6 terminated, 2 recruiting, 2 withdrawn. 205 Not applicable, 6 Phase 2, 3 Phase 1, 3 Phase 4, 1 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of ACUVUE® OASYS MAX 1-Day Multifocal and DAILIES® AquaComfort Plus® Multifocal Senofilcon A, Nelfilcon A - Visual Acuity | Not applicable | Recruiting | Johnson & Johnson Vision Care, Inc. | 150 | 2026-09-10 | 2026-09-29 |
| Evaluation of Approved Contact Lenses (CR-6657) Test (Senofilcon A), Control (Serafilcon A) - Visual Acuity | Not applicable | Recruiting | Johnson & Johnson Vision Care, Inc. | 150 | 2026-09-10 | 2026-09-29 |
| Evaluation of Effect of Scatter on Visual Performance ACUVUE® OASYS 1-Day Sphere, ACUVUE® OASYS Multifocal - Visual Acuity | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 31 | 2026-02-13 | 2026-09-25 |
| Evaluation of Approved Contact Lenses B+L Infuse spherical soft contact lenses, J&J ACUVUE OASYS 1-Day spherical soft contact lenses - Visual Acuity | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 85 | 2025-09-11 | 2026-07-06 |
| Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses INFUSE® One Day Multifocal, ACUVUE® OASYS MAX 1-Day Multifocal Contact Lens - Visual Acuity, Presbyopia | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 74 | 2025-07-24 | 2026-10-15 |
| Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process Investigational daily disposable, soft, toric lenses manufactured on 4th Generation Technology (4GT) lines with extended mini-stack hydration using propylene glycol (PG) as the hydration solvent., ACUVUE® Oasys 1-Day for Astigmatism (AO1DfA) soft contact lenses manufactured on 3rd Generation Technology (3GT) legacy lines using isopropyl alcohol (IPA) as the hydration solvent. - Astigmatism | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 281 | 2025-04-25 | 2026-09-28 |
| Clinical Evaluation of Two Cosmetic Contact Lenses etafilcon A with PVP with cosmetic pattern contact lens, 1-DAY ACUVUE® DEFINE® with LACREON®, FRESH Honey - Visual Acuity | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 53 | 2025-03-30 | 2026-09-25 |
| Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear Test Lens, Control Lens - Astigmatism | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 134 | 2025-01-07 | 2026-09-28 |
| Clinical Performance of Three Daily Disposable Silicone Hydrogel Contact Lenses Test Lens 1, Test Lens 2, Test Lens 3 - Visual Acuity | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 22 | 2024-12-29 | 2026-06-05 |
| Evaluation of Lens Rotation in Habitual Wearers of Toric, Soft Contact Lenses ACUVUE OASYS 1-Day for Astigmatism (AO1DfA), Dailies Total 1 for Astigmatism (DT1fA) - Visual Acuity | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 6 | 2024-12-06 | 2026-02-11 |
| Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses JJVC Investigational Multifocal Toric Contact Lens manufactured in Senofilcon A (C3) material with UV blocker / HEV filter - Visual Acuity | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 176 | 2024-04-22 | 2025-10-28 |
| Evaluation of Acuvue Oasys 1-Day Contact Lenses in New Wearers ACUVUE OASYS® 1-DAY with HydraLuxe™ TECHNOLOGY (AO1D) - Visual Acuity | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 36 | 2024-03-26 | 2025-06-03 |
| Clinical Investigation on Assessing the Repeatability and Reproducibility of Central and Peripheral Refractive Error Experimental - Refractive Error | Completed | Johnson & Johnson Vision Care, Inc. | 30 | 2024-01-16 | 2025-04-25 | |
| Evaluating Quality of Life Benefits of ACUVUE® Theravision® With Ketotifen in Subjects With Ocular Allergies TEST Lens, CONTROL Lens - Ocular Physiology | Not applicable | Withdrawn | Johnson & Johnson Vision Care, Inc. | 2024-01-15 | 2024-02-01 | |
| Characterization of the Central and Peripheral Wavefront Aberration Profile in Pediatric Myopic Subjects Intervention - Myopia | Completed | Johnson & Johnson Vision Care, Inc. | 23 | 2023-11-16 | 2025-12-24 | |
| Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over Two Weeks of Wear Senofilcon A contact lenses (TEST), Delefilcon A contact lenses (CONTROL) - Ocular Physiology | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 67 | 2023-11-16 | 2025-06-22 |
| Characterizing the Intraocular Scattering at Different Wavelengths Adaptive Optics System (AO) - Vision, Ocular | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 31 | 2023-05-25 | 2025-10-14 |
| Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of Investigational Lubricating Eye Drops Blink® Tears eye drops in a multidose bottle, Preservative-free investigational lubricating eye drops in a Novelia® eyedropper - Visual Acuity | Phase 2 | Completed | Johnson & Johnson Vision Care, Inc. | 46 | 2023-04-06 | 2025-04-27 |
| Design Validation of Toric Contact Lenses in Senofilcon A With a Blue-Blocking Chromophore Acuvue Oasys 1 Day for Astigmatism, TRA100/TRA200 series toric contact lens with HEVL-blocking chromophore - Visual Acuity | Not applicable | Completed | Johnson & Johnson Vision Care, Inc. | 188 | 2023-03-13 | 2024-07-17 |
| Clinical Evaluation of a Multidose Preservative-free Lubricating Eye Drops Contained in Novelia® Eye Dropper in Non-Contact Lens Wearing Patients Investigational Lubricating Eye Drop in a Novelia® bottle, Blink® Tears eye Drops - Dry Eye | Phase 2 | Completed | Johnson & Johnson Vision Care, Inc. | 121 | 2023-02-23 | 2025-04-27 |
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Myopia (46) · Refractive Errors (20) · Astigmatism (18) · Presbyopia (10) · Vision Disorders (5) · Dry Eye Syndromes (4) · Hyperopia (2) · Meibomian Gland Dysfunction (2) · Orientation, Spatial (2) · Personal Satisfaction (2) · Asthenopia (1) · Esotropia (1) · Keratitis (1) · Ocular Motility Disorders (1) · Photosensitivity Disorders (1)
Eyeglasses (8) · Contact Lenses, Hydrophilic (3) · Contact Lenses (1) · Ketotifen (1)
United States (151) · United Kingdom (41) · Canada (13) · Australia (9) · Hong Kong (6) · India (5) · China (4) · Singapore (2) · Brazil (1) · Germany (1) · Japan (1) · Spain (1)
Dennis Kuwuabara, O.D. (2) · Ikuko Sugimoto, O.D. (2) · James Fujimoto, O.D. (2) · Jason Chin, O.D. (2) · Jennifer Kao, O.D. (2) · Kevin Rosin, O.D. (2) · Mark Nakano, O.D. (2) · Noel Brennan, McOptom PhD (2) · Xu Cheng (2) · Arthur B Epstein, OD (1) · Brian Pall, OD (1) · Brian Pall, OD, MS, FAAO (1) · Carlos E Leite Arieta, MD, PhD (1) · Carol Lakkis, BScOptom, PhD, PGCertOcTher (1)
PMID 36809645, PMID 18566461, PMID 19214129, PMID 20557557, PMID 20562669, PMID 25574042, PMID 25946099, PMID 27243356, PMID 27309523, PMID 27391533, PMID 28195933, PMID 30994197, PMID 31895273, PMID 39379885, PMID 40228855, PMID 42319244