Lens Diseases: Clinical Trials

917 completed, 246 unknown, 112 recruiting, 62 terminated. 721 Not applicable, 161 Phase 4, 96 Phase 3, 46 Phase 2, 25 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	721	Completed 436, Unknown 132, Recruiting 57, Terminated 28, Not yet recruiting 24, Withdrawn 20, Active not recruiting 16, Enrolling by invitation 6, Suspended 2
Phase 4	161	Completed 117, Unknown 17, Terminated 9, Withdrawn 8, Recruiting 5, Not yet recruiting 4, Active not recruiting 1
Phase 3	96	Completed 71, Unknown 9, Terminated 7, Recruiting 6, Withdrawn 3
Phase 2	46	Completed 25, Unknown 9, Active not recruiting 4, Terminated 4, Recruiting 3, Withdrawn 1
Phase 1	25	Completed 10, Recruiting 5, Unknown 4, Active not recruiting 3, Terminated 2, Withdrawn 1
Early Phase 1	5	Completed 4, Unknown 1

Follow Lens Diseases: new trials by email Literature Review of Lens Diseases trials Research Report on Lens Diseases

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Eye Health Intervention Study in Upper Manhattan Intervention, Usual Care - Glaucoma, Suspect, Diabetic Retinopathy	Not applicable	Withdrawn	Columbia University		2027-04-01	2026-05-29
Safety and Clinical Performance of the LENTIS® MAX LS-313 MF80 Compared With the Monofocal L-313 in Cataract Patients With Late Age-Related Macular Degeneration: A Multicenter Comparative Clinical Investigation. Intraocular Lens - Cataract, AMD - Age-Related Macular Degeneration	Not applicable	Not yet recruiting	Teleon Surgical B.V.	35	2027-02-01	2026-11-04
Effects of Oxygen Cage Support During Cataract Surgery Oxygen Support Cage - Cataract	Not applicable	Not yet recruiting	Ataturk University	70	2026-12-28	2026-11-05
Study on Eye-Brain Cross-Organ Mapping and Systemic Disease Association Based on Multimodal Big Data No interventions were involved in this study. - Cataract, Vitreous Hemorrhage		Not yet recruiting	Beijing Friendship Hospital	208000	2026-12-25	2026-10-16
Postoperative Outcome Verification of Discrepant Toric IOL Calculator Recommendations After Cataract Surgery Standardized Postoperative Outcome Visit, Toric IOL Calculator Pathways (Exposure) - Cataract		Not yet recruiting	Vienna Hospital Association	128	2026-11-01	2026-10-19
Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract Surgery IOL, Cataract		Not yet recruiting	Rayner Intraocular Lenses Limited	92	2026-11-01	2026-09-10
PureSee/Odyssey Mix-and-Match IOL Mix-and-match PureSee/Odyssey cohort - Cataract		Not yet recruiting	Gainesville Eye Associates	40	2026-11-01	2026-10-27
Trial to Investigate the Safety and Effectiveness of the KI-362-US1 (YP2.2VM) Intraocular Lens (IOL) in Adult Participants for Correction of Aphakia Following Cataract Extraction KI-362-US1 (YP2.2VM) - Aphakia, Postcataract	Not applicable	Recruiting	Kowa Research Institute, Inc.	340	2026-10-30	2026-11-13
Clinical Evaluation of a Novel Trifocal IOL LPYWT0, PXYWT0, Cataract Surgery - Aphakia, Cataract	Not applicable	Recruiting	Alcon Research	66	2026-10-09	2026-10-21
Imaging and Spectral Analysis of the Crystalline Lens Using the "HYPERLAF" Slit Lamp Non-contact observation of the crystalline lens nucleus - Cataract	Not applicable	Not yet recruiting	Centre Hospitalier Universitaire de Saint Etienne	50	2026-10-01	2026-10-15
Partial Range Of Field IOLs in DMEK-Enabled Procedures combined cataract and lamellar endothelial keratoplasty - Cataract, Fuchs Endothelial Corneal Dystrophy	Not applicable	Not yet recruiting	Universitair Ziekenhuis Brussel	10	2026-10-01	2026-08-25
Combined Phacoemulsification-Goniotomy in Primary Open-Angle and Primary Angle-Closure Glaucoma Combined Phacoemulsification and Goniotomy - Primary Open-Angle Glaucoma, Primary Angle-Closure Glaucoma	Not applicable	Not yet recruiting	Assiut University	70	2026-10-01	2026-09-16
Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-Match TECNIS PureSee IOL (Model DEN00V/DET150), TECNIS Odyssey IOL (Model DRN00V/DRT150) - Presbyopia Correction, Presbyopia	Phase 4	Not yet recruiting	Dr. Daniel H. Chang, MD	68	2026-10-01	2026-10-06
A Case-Control Study Revealing Intraocular Microenvironment Characteristics in Patients With Ocular Diseases Based on Multi-Omics Analysis Not applicable- observational study - Age- Related Macular Degeneration, Diabetic Retinopathy		Not yet recruiting	First Affiliated Hospital of Zhejiang University	150	2026-10-01	2026-10-27
Intracameral Levofloxacin Versus Moxifloxacin After Cataract Surgery Levofloxacin, Moxifloxacin - Cataract, Postoperative Endophthalmitis	Not applicable	Not yet recruiting	Assiut University	93	2026-09-26	2026-09-30
A Multi Center Evaluation of TearCare on Surgical Measurements Before Cataract Surgery Manual expression of meibomian glands after thermal eyelid therapy - Dry Eye Syndrome (DES), Meibomian Gland Dysfunction (Disorder)		Recruiting	Cleveland Eye Clinic	36	2026-09-22	2026-11-10
Katarak Surgery and Care Cataract Surgery Deneyimi, Cataract Surgery		Not yet recruiting	Eastern Mediterranean University	60	2026-09-21	2026-09-08
Clinical Trial on the Visual Function of Enhanced Monofocal and EDoF Intraocular Lenses Intraocular lens - Cataract	Not applicable	Not yet recruiting	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	90	2026-09-21	2026-07-20
Can Tailored Surgical Incisions Reduce Refractive Error and Dependence on Glasses After Cataract Surgery? Adapted clear corneal incisions - Cataract (Post-operative Cataract Surgery Follow-up), Refraction Error	Not applicable	Not yet recruiting	Linkoeping University	100	2026-09-15	2026-06-03
Clinical Evaluation of the Adaptilens Accommodating IOL Accomodating Intra Ocular Lens, Monofocal Intra Ocular Lens - Aphakia Cataract	Not applicable	Not yet recruiting	Adaptilens, Inc.	100	2026-09-01	2026-08-06

Showing 20 of 1476. Sign in to see all of them.

Narrower conditions

Cataract (1417)  ·  Astigmatism (98)  ·  Presbyopia (81)  ·  Glaucoma (78)  ·  Aphakia (67)  ·  Glaucoma, Open-Angle (43)  ·  Inflammation (33)  ·  Dry Eye Syndromes (29)  ·  Macular Degeneration (28)  ·  Refractive Errors (28)  ·  Diabetic Retinopathy (25)  ·  Pseudophakia (24)  ·  Pain (21)  ·  Myopia (20)  ·  Macular Edema (19)

Broader conditions

Eye Diseases (1459)  ·  Refractive Errors (181)  ·  Pathological Conditions, Signs and Symptoms (137)  ·  Signs and Symptoms (98)  ·  Ocular Hypertension (95)  ·  Retinal Diseases (70)  ·  Pathologic Processes (64)  ·  Neurologic Manifestations (62)  ·  Nervous System Diseases (49)  ·  Retinal Degeneration (49)  ·  Endocrine System Diseases (44)  ·  Cardiovascular Diseases (38)  ·  Vascular Diseases (35)  ·  Corneal Diseases (34)

Interventions

Cataract Extraction (135)  ·  Phacoemulsification (57)  ·  Lens Implantation, Intraocular (23)  ·  prednisolone acetate (22)  ·  Lenses, Intraocular (21)  ·  Calcium Dobesilate (20)  ·  Dexamethasone (16)  ·  Ophthalmic Solutions (16)  ·  bromfenac (16)  ·  nepafenac (16)  ·  Ketorolac (12)  ·  Moxifloxacin (12)  ·  Triamcinolone Acetonide (8)  ·  Methylprednisolone (7)  ·  Trabeculectomy (7)

Sponsors

Alcon Research (118)  ·  Bausch & Lomb Incorporated (37)  ·  Beaver-Visitec International, Inc. (36)  ·  Sun Yat-sen University (33)  ·  Johnson & Johnson Surgical Vision, Inc. (26)  ·  Vienna Institute for Research in Ocular Surgery (26)  ·  National Eye Institute (NEI) (25)  ·  Medical University of Vienna (22)  ·  Prim. Prof. Dr. Oliver Findl, MBA (21)  ·  Wenzhou Medical University (21)  ·  Second Affiliated Hospital, Zhejiang University, School of Medicine (20)  ·  Abbott Medical Optics (19)  ·  Zhongshan Ophthalmic Center, Sun Yat-sen University (17)  ·  Democritus University of Thrace (16)  ·  Carl Zeiss Meditec AG (14)

Countries

United States (430)  ·  China (154)  ·  Austria (99)  ·  France (62)  ·  Spain (61)  ·  Germany (58)  ·  United Kingdom (39)  ·  Canada (32)  ·  India (30)  ·  Egypt (29)  ·  Italy (26)  ·  Switzerland (24)  ·  Turkey (Türkiye) (23)  ·  Brazil (21)  ·  Mexico (21)

Top investigators

Georgios Labiris, MD, PhD (11)  ·  Oliver Findl, MD (9)  ·  Haotian Lin, M.D., Ph.D (8)  ·  Weirong Chen, M.D. (8)  ·  Yizhi Liu, M.D., Ph.D (8)  ·  Nino Hirnschall, MD (6)  ·  Oliver Findl, MD, MBA (6)  ·  Jin Yang (5)  ·  John Hovanesian, MD (5)  ·  Yune Zhao (5)

Results publications

PMID 21940140, PMID 12424394, PMID 14977340, PMID 17276271, PMID 22310081, PMID 22425363, PMID 22969289, PMID 23332118, PMID 23332253, PMID 23522584, PMID 23680631, PMID 23688874, PMID 23803880, PMID 24075158, PMID 24203808, PMID 24355720, PMID 24935281, PMID 25030780, PMID 25527752, PMID 26869384, PMID 27072861, PMID 27385761, PMID 27557655, PMID 27680993, PMID 27810317, PMID 28670710, PMID 28991333, PMID 29605469, PMID 29661934, PMID 32600261, PMID 35082481, PMID 35749069, PMID 41621045, PMID 42192627, PMID 10724823, PMID 10801969, PMID 10922206, PMID 10937547, PMID 11097601, PMID 11448327, PMID 11470690, PMID 11594942, PMID 11594943, PMID 11815354, PMID 11925463, PMID 12231329, PMID 12928267, PMID 13129879, PMID 14289827, PMID 14508260

NIH funding

2016 (2), 2005 (1), 2009 (1), 2019 (1), 2025 (1), K23AG072035 (1), K23EY026098 (1), R01AG015812 (1), R01AG030114 (1), R01EY014418 (1), R01EY018184 (1), U01DP006436 (1), U01DP006441 (1), U01DP006827 (1), U01EY028079 (1)