10 completed, 5 unknown, 3 recruiting, 2 active not recruiting. 23 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 23 | Completed 10, Unknown 5, Recruiting 3, Active not recruiting 2, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
Follow Rectal Neoplasms: new trials by email Literature Review of Rectal Neoplasms trials Research Report on Rectal Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Next Generation STAR-TREC (NG-ST) - Organ Preservation in Early Rectal Cancer Capecitabine + Radiotherapy, Total Mesorectal Excision (TME) - Rectal Cancer | Phase 4 | Not yet recruiting | Vastra Gotaland Region | 90 | 2026-03-12 | 2026-03-19 |
| SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak SIS-reinforced anastomosis - Rectal Cancer | Phase 4 | Recruiting | Beijing Chao Yang Hospital | 966 | 2025-10-21 | 2026-06-17 |
| Neoadjuvant Therapy （NALIRIFOX） for Locally Advanced Colon and Upper Rectal Cancer NALIRIFOX - Colorectal Cancer (CRC) | Phase 4 | Active not recruiting | Affiliated Cancer Hospital of Shantou University Medical College | 57 | 2025-05-15 | 2025-06-13 |
| TES RCT Fleet Enema vs Oral Mechanical Bowel Prep Fleet Enema, Pico-Salax - Colorectal Neoplasms, Surgery | Phase 4 | Recruiting | Nova Scotia Health Authority | 66 | 2022-03-16 | 2026-08-21 |
| UGT1A1-Based Irinotecan Therapy for Locally Advanced Rectal Cancer Neoadjuvant chemoradiotherapy based on irinotecan - Rectal Cancer Stage III | Phase 4 | Recruiting | Zhejiang Cancer Hospital | 606 | 2022-01-01 | 2021-12-08 |
| Enhanced Recovery After Laparoscopic Colorectal Surgery Bupivacaine Injection - Rectal Cancer, Postoperative Pain | Phase 4 | Completed | University Hospital of North Norway | 10 | 2022-01-01 | 2022-12-22 |
| Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients low-dose neuroleptanalgesia, Placebo - Stomach Neoplasms, Colonic Neoplasms | Phase 4 | Unknown | RenJi Hospital | 200 | 2021-10-05 | 2021-10-06 |
| Total Neoadjuvant Therapy in Rectal Cancer Treatment Concurrent Chemoradiotherapy, TME, consolidation chemotherapy - Rectal Cancer | Phase 4 | Unknown | State Scientific Centre of Coloproctology, Russian Federation | 280 | 2020-10-30 | 2021-02-15 |
| Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery Oral Antibiotics, Placebo, Mechanical Bowel Preparation - Rectal Adenocarcinoma, Rectum Neoplasm | Phase 4 | Active not recruiting | Helsinki University Central Hospital | 604 | 2020-03-18 | 2022-11-17 |
| Implementation of Pre-emptive Geno- and Phenotyping in 5-Fluorouracil- or Capecitabine-treated Patients 5-Fluorouracil - Colon Cancer, Stomach Tumor | Phase 4 | Unknown | Jessa Hospital | 250 | 2020-02-18 | 2020-02-13 |
| Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery Acetaminophen, Gabapentin, Orphenadrine - Colon Cancer, Colon Diverticulosis | Phase 4 | Unknown | University of Illinois College of Medicine at Peoria | 80 | 2017-01-01 | 2017-03-20 |
| Cancer and Anesthesia: Survival After Radical Surgery - a Comparison Between Propofol or Sevoflurane Anesthesia Propofol, Sevoflurane - Breast Neoplasms, Colonic Neoplasms | Phase 4 | Completed | Uppsala University | 5774 | 2013-11-01 | 2022-12-14 |
| Early Intervention for Erectile Dysfunction After Laparoscopic Resection for Rectal Cancer vacuum erection device - Rectal Tumors, Erectile Dysfunction | Phase 4 | Completed | Nanfang Hospital, Southern Medical University | 90 | 2013-05-01 | 2015-06-18 |
| Transanal Endoscopic Microsurgery Versus Endoscopic Submucosal Dissection For Large Rectal Adenomas TEM - Transanal Endoscopic Microsurgery, ESD - Endoscopic Submucosal Dissection - RECTAL NEOPLASMS | Phase 4 | Withdrawn | European Association for Endoscopic Surgery | 2012-01-01 | 2023-09-08 | |
| Prospective Randomized Study of SILS Versus CLS for Rectal Cancer Single Incision Laparoscopic Surgery - Rectal Cancer, Adenocarcinoma | Phase 4 | Completed | Hvidovre University Hospital | 40 | 2011-09-01 | 2013-02-05 |
| The Effect of Dexmedetomidine on Postoperative Analgesia Fentanyl, Dexmedetomidine - Colon Cancer, Rectal Cancer | Phase 4 | Completed | Seoul National University Hospital | 95 | 2011-06-01 | 2012-03-08 |
| The Efficacy of Penile Rehabilitation Using Udenafil After Total Mesorectal Excision of Rectal Cancer Placebo drug, Udenafil - Rectal Cancer | Phase 4 | Completed | Kyungpook National University Hospital | 80 | 2009-10-01 | 2015-03-10 |
| NITI CAR27 (ColonRing) Compression Anastomosis in Colorectal Surgery Compression Anastomosis Device, follow-up colonoscopy - Colonic Neoplasms, Rectal Neoplasms | Phase 4 | Completed | St John of God Hospital, Vienna | 62 | 2008-10-01 | 2014-01-29 |
| Concentration of Ertapenem in Colorectal Tissue Ertapenem - Diverticulosis, Colonic, Rectal Neoplasms | Phase 4 | Completed | University of Ulm | 23 | 2007-09-01 | 2017-02-10 |
| Relationship Between Platinum Levels in the Blood and Neurotoxicity in Patients Who Are Receiving Oxaliplatin for Gastrointestinal Cancer oxaliplatin, management of therapy complications - Cancer | Phase 4 | Unknown | GERCOR - Multidisciplinary Oncology Cooperative Group | 58 | 2005-10-01 | 2011-12-05 |
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Colonic Neoplasms (10) · Colorectal Neoplasms (6) · Stomach Neoplasms (3) · Anus Neoplasms (2) · Diverticulosis, Colonic (2) · Esophageal Neoplasms (2) · Pain, Postoperative (2) · Pancreatic Neoplasms (2) · Adenocarcinoma (1) · Agnosia (1) · Anastomotic Leak (1) · Appendiceal Neoplasms (1) · Bile Duct Neoplasms (1) · Breast Neoplasms (1)
Digestive System Diseases (23) · Digestive System Neoplasms (23) · Gastrointestinal Diseases (23) · Gastrointestinal Neoplasms (23) · Intestinal Diseases (23) · Intestinal Neoplasms (23) · Neoplasms by Site (23) · Rectal Diseases (23) · Neoplasms (22) · Colorectal Neoplasms (17) · Colonic Diseases (14) · Pathological Conditions, Signs and Symptoms (6) · Pathologic Processes (5) · Postoperative Complications (5) · Nervous System Diseases (3)
Capecitabine (3) · Bupivacaine (2) · Fentanyl (2) · Fluorouracil (2) · Oxaliplatin (2) · Radiotherapy (2) · Acetaminophen (1) · Anti-Bacterial Agents (1) · Chemoradiotherapy (1) · Chemotherapy, Adjuvant (1) · Consolidation Chemotherapy (1) · Dexmedetomidine (1) · Ertapenem (1) · Gabapentin (1) · Hydrocodone (1)
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