16 completed, 15 unknown, 8 not yet recruiting, 5 recruiting. 28 Not applicable, 5 Phase 2, 4 Phase 1, 4 Phase 4, 3 Phase 3.
Follow Pulp Disease, Dental: new trials by email Literature Review of Pulp Disease, Dental trials Research Report on Pulp Disease, Dental
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Outcomes of Root Canal Treatment Using Modern Irrigation Protocols GentleWave®, EdgePRO™, Fotona LightWalker® - Pulp Disease, Dental | Not applicable | Not yet recruiting | University of Illinois at Chicago | 200 | 2026-09-01 | 2026-10-01 |
| Oxymetazoline Versus Sodium Hypochlorite as Hemostatic Agents in MTA Pulpotomy of Primary Molars Oxymetazoline 0.05% nasal solution, Sodium Hypochlorite Solution - Pulp Disease, Dental, Pulp Therapy in Primary Molars | Not applicable | Not yet recruiting | Cairo University | 50 | 2026-08-01 | 2026-06-30 |
| Chloramphenicol, Tetracycline, Zinc Oxide and Eugenol Paste (CTZ Paste) for Emergency Dental Treatment in Public Health Settings: A Randomized Trial CTZ Paste, ZOE Pulpectomy - Pulp Disease, Dental, Pulp Necrosis | Early Phase 1 | Not yet recruiting | University of Sao Paulo | 110 | 2026-06-08 | 2026-05-12 |
| Effect of Different Bioactive Restorative Materials and Techniques on Pulpal Condition Bioactive Restorative Materials - Pulp Disease, Dental | Not applicable | Completed | Dina Ashraf | 30 | 2026-03-15 | 2026-07-20 |
| Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker vital pulp treatment - Pulp Disease, Dental, Pulpitis | Not applicable | Recruiting | Abeer Ghalib Abdul-khaliq | 60 | 2026-02-20 | 2026-04-01 |
| The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament Diclofenac Sodium, Calcium hydroxide - Endodontic Disease, Pulp Disease, Dental | Phase 2 / Phase 3 | Recruiting | British University In Egypt | 48 | 2025-11-01 | 2025-05-30 |
| In Vivo-Ex Vivo Evaluation of the Root ZX3 for Working-Length Determination Root ZX3 Electronic Apex Locator - Apical Periodontitis, Pulp Disease, Dental | Not applicable | Completed | Riyadh Elm University | 41 | 2025-10-19 | 2026-07-08 |
| Comparison of Hyaluronic Acid, TheraCal, and Mineral Trioxide Aggregate as Pulpotomy Agents in Primary Molars Hyaluronic Acid (HA), TheraCal, Mineral Trioxide Aggregate - Pulpotomies Primary Teeth, Pulp Disease, Dental | Not applicable | Not yet recruiting | Al-Azhar University | 66 | 2025-10-01 | 2025-09-11 |
| Comparison of 3Mixtatin Pulpotomy and Metapex Pulpectomy in Primary Molars With Irreversible Pulpitis Metapex, 3Mixtatin - Irreversible Pulpitis, Primary Teeth | Phase 1 | Not yet recruiting | Cairo University | 50 | 2025-06-01 | 2025-04-27 |
| Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate in Vital Pulpotomy in Primary Molars Potassium Nitrate in Polycarboxylate cement, MTA-Anglus - Vital Pulp Therapies, Pulpotomy | Not applicable | Not yet recruiting | Cairo University | 50 | 2025-05-30 | 2025-03-12 |
| The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy Biodentine - Pulp Exposure, Dental, Pulp Disease, Dental | Active not recruiting | Ataturk University | 96 | 2025-05-02 | 2025-11-18 | |
| Clinical and Radiographic Evaluation of Hyaluronic Acid (Gengigel Teething) Versus Mineral Trioxide Aggregate( Angelus) as Pulpotomy Agent in Vital Primary Molars Hyaluronic acid pulpotomy, mineral trioxide aggregate pulpotomy - Pulpotomies Primary Teeth, Pulp Disease, Dental | Phase 1 | Not yet recruiting | Cairo University | 34 | 2025-03-01 | 2024-11-04 |
| Evaluation of Success Rate of Partial Pulpotomy Versus Complete Pulpotomy in Primary Molars Using NeoPUTTY MTA Partial Pulpotomy, Complete pulpotomy - Pulp Disease, Dental | Not applicable | Unknown | Cairo University | 60 | 2024-09-22 | 2024-08-14 |
| Knowledge of Vital Pulp Therapy in Permanent Teeth After Educational Programme: A Before and After Study Educational programme about vital pulp therapy - Pulp Disease, Dental, Knowledge | Unknown | Cairo University | 550 | 2024-09-01 | 2024-06-21 | |
| Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication Calcium hydroxide, nano calcium hydroxide - Endodontic Disease, Pulp Disease, Dental | Phase 2 / Phase 3 | Unknown | British University In Egypt | 54 | 2024-08-01 | 2024-08-19 |
| 3Mixtatin and MTA Vital Pulpotomy in Primary Molars 3 mixtatin pulpotomy, MTA pulpotomy - Pulp Disease, Dental, Deciduous Teeth | Phase 1 | Unknown | Cairo University | 50 | 2024-08-01 | 2024-06-27 |
| The Effect of Different Risk Factors on the Success Rate of VPT with Biodentine, with MTA - Dental Caries Extending to Pulp, Pulp Disease, Dental | Recruiting | Semmelweis University | 400 | 2024-06-01 | 2025-03-06 | |
| Effect of Cavity Disinfectants on Post Operative Pain & Success of Partial Caries Removal Selective caries removal, Selective caries removal with NaOCl, Selective caries removal with CHX - Pulp Disease, Dental | Not applicable | Recruiting | Postgraduate Institute of Dental Sciences Rohtak | 159 | 2024-05-23 | 2025-02-20 |
| Outcomes of NeoMTA and NeoPUTTY Pulpotomies in Primary Molars Primary molars pulpotomies with NeoMTA, Primary molar pulpotomies with NeoPUTTY - Pulp Disease, Dental | Not applicable | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 50 | 2024-04-01 | 2024-04-23 |
| Assessment of Inflammatory Biomarkers in Molar-Incisor Hypomineralization-Affected First Permanent Molars Pulpal Blood Sample - Molar-Incisor Hypomineralization (MIH), Pulp Disease, Dental | Not applicable | Completed | Marmara University | 83 | 2024-03-04 | 2025-12-15 |
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Dental Pulp Diseases (46) · Pulpitis (5) · Dental Caries (4) · Periapical Periodontitis (4) · Dental Pulp Necrosis (3) · Pain, Postoperative (2) · Bites and Stings (1) · Child Behavior (1) · Dental Leakage (1) · Dental Pulp Exposure (1) · Dentin Sensitivity (1) · Fistula (1) · Inflammation (1) · Molar Hypomineralization (1) · Pain (1)
Tooth Diseases (46) · Stomatognathic Diseases (45) · Pathological Conditions, Signs and Symptoms (6) · Jaw Diseases (5) · Mouth Diseases (5) · Periapical Diseases (5) · Periodontal Diseases (5) · Periodontitis (5) · Neurologic Manifestations (4) · Pathologic Processes (4) · Signs and Symptoms (4) · Tooth Demineralization (4) · Necrosis (3) · Pain (3) · Postoperative Complications (2)
Pemetrexed (5) · Sodium Hypochlorite (3) · formocresol (3) · mineral trioxide aggregate (3) · tricalcium silicate (3) · Calcium Hydroxide (2) · Epinephrine (2) · Mepivacaine (2) · Oxymetazoline (2) · Pulpotomy (2) · potassium nitrate (2) · Carticaine (1) · Crowns (1) · Dental Prosthesis (1) · Dental Pulp Capping (1)
Cairo University (10) · British University In Egypt (4) · Ain Shams University (3) · Minia University (3) · Al-Azhar University (2) · Ataturk University (2) · Tanta University (2) · Abeer Ghalib Abdul-khaliq (1) · Dina Ashraf (1) · Future University in Egypt (1) · Hacettepe University (1) · Izmir Katip Celebi University (1) · Louisiana State University Health Sciences Center in New Orleans (1) · Marmara University (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1)
Egypt (19) · Turkey (Türkiye) (6) · Iraq (2) · Saudi Arabia (2) · United States (2) · Hungary (1) · India (1) · Jordan (1) · Spain (1)
Shehab Eldin M Saber, doctoral (2) · Abeer G Abdulkhaliq (1) · Abier Fahad Alhekeir (1) · Anas F Mahdee, professor (1) · Asya A. Almansour, SBPD (1) · Atyaf A. Alhunti (1) · Bekir Karabucak, DMD, MS (1) · Dina Abdelwahab, M.Sc. (1) · Dr Sanjay Tewari, MDS (1) · Hany M. Saber, PHD (1)
PMID 12406376, PMID 12849707, PMID 18534173, PMID 19067439, PMID 23240887, PMID 24932190, PMID 25215141, PMID 26062864, PMID 26578117, PMID 26662488, PMID 26950810, PMID 28600966, PMID 28780718, PMID 29122067, PMID 29852056, PMID 30238414, PMID 30246755, PMID 30611989, PMID 30992107, PMID 31202439, PMID 32204501, PMID 32742096, PMID 34321144, PMID 34501145, PMID 35536159, PMID 36580161, PMID 37865418, PMID 38281619, PMID 38504243, PMID 39219956, PMID 39407247, PMID 42530796, PMID 9198445