31 completed, 13 unknown, 5 not yet recruiting, 1 active not recruiting. 29 Not applicable, 10 Phase 2, 7 Phase 4, 6 Phase 3, 4 Phase 1.
Follow mineral trioxide aggregate: new trials by email Literature Review of mineral trioxide aggregate trials Research Report on mineral trioxide aggregate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Salvadora Persica-Zinc Oxide Versus MTA as Pulpotomy Agents in Mature Permanent Molars With Irreversible Pulpitis Mineral Trioxide Aggregate, Salvadora persica Extract + Zinc Oxide - Irreversible Pulpitis | Not applicable | Not yet recruiting | Postgraduate Medical Institute, Lahore | 78 | 2026-06-20 | 2026-06-05 |
| Comparative Evaluation of Calcium Silicate-doped Treated Dentin Matrix and Mineral Trioxide Aggregate as Miniature Pulpotomy Biomaterials in Deep Carious Lesions Calcium Silicate doped treated dentin matrix for miniature pulpotomy (CaSi+hTDM MP)., Mineral Trioxide Aggregate (MTA) for Miniature Pulpotomy - Reversible Pulpitis, Deep Carious Lesions | Not applicable | Not yet recruiting | All India Institute of Medical Sciences | 56 | 2026-04-25 | 2026-03-10 |
| Total Pulpotomy With Two Repair Cements in Hypomineralized Teeth MTA group, CIMMO DTA® group - Molar-Incisor Hypomineralization (MIH) | Not applicable | Active not recruiting | Meire Coelho Ferreira | 120 | 2026-04-16 | 2026-08-20 |
| Comparison of Hyaluronic Acid, TheraCal, and Mineral Trioxide Aggregate as Pulpotomy Agents in Primary Molars Hyaluronic Acid (HA), TheraCal, Mineral Trioxide Aggregate - Pulpotomies Primary Teeth, Pulp Disease, Dental | Not applicable | Not yet recruiting | Al-Azhar University | 66 | 2025-10-01 | 2025-09-11 |
| Clinical and Radiographic Evaluation of Indirect Pulp Capping Using Platelet Rich Fibrin Versus Mineral Trioxide Aggregate in Deep Carious Molars: a Randomized Controlled Trial MTA, PRF - Dental Caries, Pulp Caping | Phase 2 | Not yet recruiting | Cairo University | 50 | 2025-06-01 | 2025-03-21 |
| Outcome of Pulpotomy With MTA and Biodentin in Permanent Teeth With Caries Exposure Pulp Therapy with Mineral trioxide aggregate (MTA), Pulp Therapy with Biodentine - Pulpitis - Irreversible | Not applicable | Not yet recruiting | Altamash Institute of Dental Medicine | 136 | 2025-05-02 | 2025-04-24 |
| TheraCal Materials Versus MTA in Full Pulpotomy Mineral Trioxide Aggregate (MTA), Theracal LC, TheraCal PT - Pulpitis - Irreversible | Not applicable | Completed | Cukurova University | 72 | 2024-12-16 | 2026-06-25 |
| A Comparative Analysis of Biomaterials for Retrograde Filling in Apical Surgery. Mineral Trioxide Aggregate, BioCeramic Root Repair Material Fast Set Putty. - Periapical Lesion | Not applicable | Completed | University of Valencia | 110 | 2024-02-08 | 2026-07-13 |
| Premixed Bioceramic Putty as an Apical Plug in Immature Anterior Permanent Teeth Mineral trioxide aggregate, Premixed Bioceramic Putty - Periapical Periodontitis | Not applicable | Completed | Tanta University | 50 | 2023-11-22 | 2025-04-18 |
| Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis Epigallocatechin gallate (EGCG), Sodium hypochlorite (NaOCl), Mineral trioxide aggregate (MTA) - Irreversible Pulpitis | Not applicable | Completed | Cairo University | 64 | 2023-07-01 | 2026-08-24 |
| Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study Mineral trioxide aggregate (dressing material), Melatonin (dressing material) - Dental Caries in Children, Vital Pulp Therapy | Not applicable | Unknown | Suez Canal University | 45 | 2023-05-20 | 2024-08-02 |
| Simvastatin Versus MTA in Pulpotomy of Immature Permanent Molars Simvastatin - Pulp Exposure, Dental | Early Phase 1 | Unknown | Ahmad Elheeny | 128 | 2023-04-01 | 2023-05-26 |
| Evaluation of Conservative Management of Teeth With Deep Cavitated Carious Lesions RetroMTA, TheraCal, Fuji IX - Deep Caries, Pulp Exposure, Dental | Phase 2 / Phase 3 | Unknown | Cairo University | 90 | 2023-01-01 | 2023-12-15 |
| Clinical And Radiographic Evaluation Of Nano-Propolis, Nano-Curcumin and MTA as Direct Pulp Capping Agents in Young Permanant Teeth MTA Cement, propolis nano particle, curcumin nanoparticles - Traumatic Pulp Exposure in Children | Phase 1 | Completed | Al-Azhar University | 54 | 2022-12-20 | 2025-07-11 |
| Clinical and Histological Evaluation of Hesperidin as a Direct Pulp Capping Material Hesperidin, Mineral Trioxide Aggregate (MTA) - Pulp Exposure, Dental, Dental Pulp Capping | Not applicable | Completed | Cairo University | 32 | 2022-09-01 | 2024-05-07 |
| Comparing Two Indirect Pulp Capping Agents for Permanent Teeth Silver diamine fluoride, Mineral trioxide aggregate - Deep Caries | Not applicable | Unknown | Cairo University | 30 | 2022-08-01 | 2022-06-21 |
| Survival Rate After TheraCal PT Pulpotomy Versus MTA Pulpotomy in Children With Vital Primary Molars. MTA, TheraCal PT - Reversible Pulpitis | Not applicable | Unknown | Cairo University | 20 | 2022-03-01 | 2022-03-04 |
| Evaluation of Apexogenesis With Human Treated Dentin Matrix in Young Permanent Molars human treated dentin matrix, Mineral Trioxide Aggregate - Dentin Bridge | Phase 1 / Phase 2 | Completed | nora mostafa mohammed abo shanady | 20 | 2022-01-18 | 2024-07-30 |
| Pulpotomy Materials in Primary Molars Mineral Trioxide Aggregate (MTA), Biodentine, Ferric Sulfate - Dental Caries, Pulpitis | Not applicable | Completed | Sacide Duman | 22 | 2022-01-01 | 2025-08-13 |
| Direct Pulp Capping in Primary Molars Mineral trioxide aggregate (MTA), Hard setting Calcium Hydroxide (Dycal) - Direct Pulp Capping | Phase 3 | Completed | Mansoura University | 52 | 2022-01-01 | 2023-09-26 |
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Dental Pulp Exposure (9) · Dental Pulp Necrosis (5) · Pulpitis (5) · Dental Caries (4) · Dental Pulp Diseases (4) · Periapical Periodontitis (4) · Stomatognathic Diseases (2) · Tooth Diseases (2) · Alveolar Bone Loss (1) · Molar Hypomineralization (1) · Mouth Diseases (1) · Necrosis (1) · Periapical Diseases (1) · Signs and Symptoms (1) · Tooth Injuries (1)
Cairo University (9) · Al-Azhar University (2) · Gihan M Abuelniel ,PhD (2) · Jordan University of Science and Technology (2) · Mansoura University (2) · Ahmad Elheeny (1) · Ain Shams University (1) · All India Institute of Medical Sciences (1) · Altamash Institute of Dental Medicine (1) · Altinbas University (1) · Amany hasanean Abd El sadek (1) · Assistance Publique - Hôpitaux de Paris (1) · Azad University of Medical Sciences (1) · Cukurova University (1) · Ege University (1)
Egypt (17) · Turkey (Türkiye) (5) · United States (4) · Iran (3) · India (2) · Jordan (2) · Pakistan (2) · Brazil (1) · Chile (1) · China (1) · Denmark (1) · France (1) · Poland (1) · Saudi Arabia (1) · Spain (1)
Lama Awawdeh, PhD (2) · A Y El Hosainy, PhD (1) · Afnan M Saber, MSc (1) · Alicja Nowicka, DDS, PhD (1) · Ann Wenzel, professor (1) · C C Youngson (1) · Claudia Brizuela (1) · Dina Abdelwahab, M.Sc. (1) · Domenico Ricucci, MD, DDS (1) · Gayatri Malik, DMD (1) · Ghada AH Elbaz, Professor (1) · Gihan M Abuelniel (1)
PMID 11585142, PMID 16536148, PMID 16805357, PMID 17256303, PMID 18565375, PMID 21752247, PMID 22838228, PMID 23550521, PMID 23690353, PMID 24959601, PMID 25467231, PMID 25872627, PMID 27175451, PMID 27377108, PMID 28206897, PMID 28692829, PMID 28836288, PMID 29070150, PMID 30864114, PMID 31321573, PMID 32041360, PMID 33440268, PMID 3481571, PMID 38281619, PMID 41353690, PMID 6957533
U01DE016750 (1)