60 completed, 18 unknown, 9 recruiting, 8 not yet recruiting. 64 Not applicable, 7 Phase 2, 7 Phase 3, 7 Phase 4, 3 Early Phase 1.
Follow this condition Literature Review of Pulpitis trials Research Report on Pulpitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Full Pulpotomy in Permanent Teeth With Irreversible Pulpitis and Apical Periodontitis Full pulpotomy - Irreversible Pulpitis With Apical Periodontitis | Not applicable | Not yet recruiting | King Abdullah University Hospital | 30 | 2026-10-07 | 2026-08-17 |
| Characterization of Pulp Inflammation: an Observational Study Using Biological Samples Collected During Routine Dental Care Pulpal Inflammation | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1200 | 2026-09-01 | 2026-04-16 | |
| Evaluation of the Effect of Different Irrigation Activation Methods During Endodontic Retreatment Xp Finisher R file - Endodontic Inflammation | Not applicable | Recruiting | Minia University | 34 | 2026-08-01 | 2026-08-21 |
| Metagenomic Analysis and Postoperative Pain in Infected Root Canals Using Different Irrigation Protocols Ultrasonic Irrigation Activation, Laser-Activated Irrigation, Mechanical Irrigation Activation - Dental Pulp Necrosis, Pulpitis | Not applicable | Not yet recruiting | Suez Canal University | 40 | 2026-04-30 | 2026-05-04 |
| Total Pulpotomy With Two Repair Cements in Hypomineralized Teeth MTA group, CIMMO DTA® group - Molar-Incisor Hypomineralization (MIH) | Not applicable | Active not recruiting | Meire Coelho Ferreira | 120 | 2026-04-16 | 2026-08-20 |
| Effects of Topical Anesthesia Approaches on Dental Pain During and After Restorative Management of Dental Caries Photobiomodulation (PBM)-induced analgesia device using multi-wavelength LED, Medicated analgesia, Placebo - Pulpitis, Pain Management | Not applicable | Not yet recruiting | Dubai Health | 204 | 2026-04-15 | 2026-04-13 |
| Clinical and Radiographic Evaluation of Primary Endodontic Treatment and Non-surgical Endodontic Retreatments Root canal treatment and non surgical endodontic retreatment - Periapical Periodontitis, Pulpitis | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 75 | 2026-03-15 | 2026-02-18 | |
| Buffered Versus Conventional Local Anesthesia for Pain and Anxiety Reduction in School-Aged Children With Pulpitis Buffered Lidocaine with Epinephrine, idocaine with Epinephrine (Conventional) - Pulpitis | Not applicable | Recruiting | Universidad Autonoma de San Luis Potosí | 60 | 2026-03-02 | 2026-06-10 |
| Measurement of Pro-resolving Inflammation Biomarkers in Saliva, Gingival Fluid, and Dental Pulp in Patients With Symptomatic Pulpitis and Healthy Controls Pulpitis, Healthy | Not yet recruiting | Université de Nantes | 50 | 2026-03-01 | 2026-03-04 | |
| Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker vital pulp treatment - Pulp Disease, Dental, Pulpitis | Not applicable | Recruiting | Abeer Ghalib Abdul-khaliq | 60 | 2026-02-20 | 2026-04-01 |
| Comparison of Aquaporin -4, -5, -9 and IL-8 Levels in GCF, Dentin Fluid and Pulp Samples Pulpitis, Pulpitis - Irreversible | Not yet recruiting | Kırıkkale University | 70 | 2025-12-01 | 2025-12-01 | |
| Vital Pulp Therapy Versus Root Canal Treatment for Irreversible Pulpitis With Incipient Apical Periodontitis Diagnosed Using Artificial Intelligence This Keeps: the Main Intervention (Vital Pulp Therapy) the Comparison (Root Canal Treatment) the Condition (Irreversible Pulpitis With Incipient Apic Vital Pulp Therapy, Root Canal Treatment - Symptomatic Irreversible Pulpitis | Not applicable | Active not recruiting | Ain Shams University | 34 | 2025-11-15 | 2026-04-24 |
| Diagnostic Validity of a Quantitative Pulp Pain Scoring System and Its Association With Postoperative Clinical Outcomes Root canal treatment procedure based on the total score obtained from the Youden symptom scoring system, Vital pulp therapy procedure based on the total score obtained from the Youden symptom scoring system - Postoperative Pain After Endodontic Treatment, Direct Pulp Capping | Not applicable | Completed | Recep Tayyip Erdogan University | 143 | 2025-11-04 | 2026-01-16 |
| Biomarkers for Differentiating Reversible and Irreversible Pulpitis Pulpal Blood Biomarker Analysis - Reversible Pulpitis, Irreversible Pulpitis | Completed | Safa | 90 | 2025-11-01 | 2026-07-31 | |
| Outcome of Selective Caries Removal Performed by Undergraduate Students Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine - Deep Caries Lesion of Pemanent Teeth | Not applicable | Active not recruiting | King Abdullah University Hospital | 100 | 2025-11-01 | 2026-08-14 |
| Effect of Menstrual Phase on the Anesthetic Efficacy Inferior Alveolar Nerve Block - Pulpitis - Irreversible | Not applicable | Recruiting | Jamia Millia Islamia | 150 | 2025-09-11 | 2026-10-08 |
| Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries Full Pulpotomy, root canal treatment and intracanal medicament - Extremely Deep Caries, Pulpitis | Not applicable | Recruiting | National University Hospital, Singapore | 93 | 2025-07-16 | 2025-11-21 |
| Postoperative Pain Evaluation After Obturation With Different Sealers AH Plus (Dentsply Sirona, Charlotte, NC, USA), NeoSealer Flo, Continuous Wave Condensation - Periapical Periodontitis, Pulpitis | Not applicable | Recruiting | University of Siena | 270 | 2025-06-01 | 2025-06-12 |
| Success of Endodontic Treatment With Different Obturation Techniques and Sealer Cements AH Plus (Dentsply Sirona, Charlotte, NC, USA), NeoSealer Flo, Continuous Wave Condensation - Pulpitis, Periapical Lesions | Not applicable | Recruiting | University of Siena | 270 | 2025-06-01 | 2025-06-13 |
| The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy Biodentine - Pulp Exposure, Dental, Pulp Disease, Dental | Active not recruiting | Ataturk University | 96 | 2025-05-02 | 2025-11-18 |
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Pain, Postoperative (14) · Dental Pulp Diseases (13) · Pain (10) · Periapical Periodontitis (8) · Dental Caries (6) · Toothache (4) · Agnosia (3) · Acute Pain (2) · Dental Pulp Exposure (2) · Dental Pulp Necrosis (2) · Disease (2) · Periodontitis (2) · Tooth Diseases (2) · Alveolar Bone Loss (1)
Stomatognathic Diseases (101) · Tooth Diseases (99) · Dental Pulp Diseases (88) · Pathological Conditions, Signs and Symptoms (31) · Neurologic Manifestations (26) · Signs and Symptoms (26) · Pathologic Processes (18) · Pain (13) · Postoperative Complications (13) · Mouth Diseases (10) · Periodontal Diseases (9) · Jaw Diseases (8) · Periapical Diseases (8) · Periodontitis (8) · Tooth Demineralization (6)
Pulpotomy (6) · Pemetrexed (5) · mineral trioxide aggregate (5) · tricalcium silicate (5) · Diclofenac (3) · Epinephrine (3) · Lasers (3) · Lidocaine (3) · Low-Level Light Therapy (3) · Carticaine (2) · Dexamethasone (2) · Prednisolone (2) · ProRoot MTA (2) · Tramadol (2) · ferric sulfate (2)
Cairo University (9) · Ain Shams University (4) · Jamia Millia Islamia (4) · King Abdullah University Hospital (3) · Postgraduate Institute of Dental Sciences Rohtak (3) · Suez Canal University (3) · Ataturk University (2) · Bulent Ecevit University (2) · Isfahan University of Medical Sciences (2) · Kırıkkale University (2) · Ondokuz Mayıs University (2) · University of Sao Paulo (2) · University of Siena (2) · Abeer Ghalib Abdul-khaliq (1) · Al-Azhar University (1)
Turkey (Türkiye) (17) · Egypt (16) · Brazil (6) · India (6) · France (4) · Iran (4) · Jordan (3) · Spain (3) · United States (3) · Taiwan (2) · Belgium (1) · Denmark (1) · Hungary (1) · Iraq (1) · Lithuania (1)
Nessrin Taha, DClinDent, PhD (2) · Abeer Elgendy, Professor (1) · Abeer G Abdulkhaliq (1) · Ahmed A Soliman, B.D.S (1) · Alessandra Reis, doctor (1) · Ali Mentes, Prof (1) · Aliaa Hamouda, MSc (1) · Amani Khalil, PhD (1) · Amatallah H Al-Rawhani, Pos (1) · Amatallah H Al-Rawhani, Postgraduate (1) · Anas F Mahdee, professor (1) · Angie G Ghoneim (1) · Asma Khan, DDS (1)
PMID 10371903, PMID 11199749, PMID 12196219, PMID 1298800, PMID 14342926, PMID 15560360, PMID 16275600, PMID 16911098, PMID 17889679, PMID 20478449, PMID 21300053, PMID 23741350, PMID 23880259, PMID 24012952, PMID 24052307, PMID 24565651, PMID 24702239, PMID 25227929, PMID 26079388, PMID 26305798, PMID 26952243, PMID 27330702, PMID 27471808, PMID 27696017, PMID 277629, PMID 27766712, PMID 28190299, PMID 28351379, PMID 29571913, PMID 29571915, PMID 30910353, PMID 31365529, PMID 31702056, PMID 32976660, PMID 35251416, PMID 35915749, PMID 36471427, PMID 37209243, PMID 38281619, PMID 3922900, PMID 41353690, PMID 4208832, PMID 42458416, PMID 42625164, PMID 42755412, PMID 6783724, PMID 6951246, PMID 8109774, PMID 8596073, PMID 9477818
2009 (1), 2015 (1)