11 completed, 8 unknown, 6 recruiting, 2 not yet recruiting. 11 Not applicable, 4 Phase 2, 2 Phase 1, 2 Phase 4.
Follow Pulmonary Artery Hypertension: new trials by email Literature Review of Pulmonary Artery Hypertension trials Research Report on Pulmonary Artery Hypertension
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Endothelial Cell Activation and Total Pulmonary Resistance in PAH XBD173 - Pulmonary Artery Hypertension | Not applicable | Not yet recruiting | Imperial College London | 6 | 2026-08-01 | 2026-03-25 |
| Sotatercept in Pulmonary Arterial Hypertension Sotatercept - Pulmonary Artery Hypertension | Phase 4 | Recruiting | University of Alberta | 27 | 2025-10-06 | 2026-07-09 |
| Non-Invasive Measurements of Changes in Pulmonary Artery Pressure in Intensive Care Unit Patients Using Electrical Impedance Tomography - A Feasibility Study Electrical impedance tomography - Pulmonary Artery Hypertension | Recruiting | Insel Gruppe AG, University Hospital Bern | 28 | 2024-08-05 | 2024-11-14 | |
| REstoration of VItamin D in Pulmonary Arterial Hypertension Calcifediol Oral Capsule, Placebo - Pulmonary Artery Hypertension, Vitamin d Deficiency | Phase 4 | Not yet recruiting | Parc de Salut Mar | 102 | 2024-07-01 | 2024-02-14 |
| Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO) BALT GoldbBAL2 Detachable Balloon, Catheter System - Congenital Diaphragmatic Hernia, Pulmonary Hypoplasia | Not applicable | Recruiting | Rodrigo Ruano | 10 | 2024-05-01 | 2026-02-23 |
| Potts-shunt for the Treatment of Pediatric Patients With Severe Pulmonary Hypertension Comprehensive therapy combined Potts-shunt procedure and conventional drug therapy, Only conventional drug therapy - Pulmonary Artery Hypertension | Not applicable | Recruiting | China National Center for Cardiovascular Diseases | 120 | 2024-04-23 | 2024-05-28 |
| Xenon MRI in Stable Pulmonary Hypertension (Jupiter AUGEAN) Hyperpolarized Xe129 - Pulmonary Artery Hypertension | Phase 2 | Withdrawn | Bastiaan Driehuys | 2024-03-15 | 2024-01-23 | |
| High Altitude (HA) Residents With Pulmonary Vascular Diseases (PVD), 6 Minute Walk Distance (6MWD) Assessed at 2840m (HA) With and Without Supplemental Oxygen Therapy (SOT) 6-minute walk distance (6MWD) test, 6-minute walk distance (6MWD) test with supplemental oxygen (3 l/min, nasal) - Pulmonary Vascular Disease, Pulmonary Artery Hypertension | Not applicable | Unknown | University of Zurich | 24 | 2023-09-23 | 2023-10-05 |
| HA Residents With PVD, SDB Assessed at HA (2840m) vs LA (Sea Level) Assessment without intervention at High altitude, Relocation to sea level for 2 days - Pulmonary Vascular Disease, Pulmonary Artery Hypertension | Not applicable | Unknown | University of Zurich | 24 | 2023-09-22 | 2023-10-10 |
| HA Residents With PVD, 6MWD Assessed at HA (2840m) vs LA (Sea Level) Relocation to sea level - Pulmonary Vascular Disease, Pulmonary Artery Hypertension | Not applicable | Unknown | University of Zurich | 24 | 2023-07-05 | 2023-10-03 |
| HA Residents With PVD, Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) With and Without Supplemental Oxygen Therapy (SOT) Supplemental oxygen therapy, Sham Oxygen therapy - Pulmonary Vascular Disorder, Pulmonary Artery Hypertension | Not applicable | Unknown | University of Zurich | 24 | 2023-07-05 | 2023-10-16 |
| Evaluation of Respiratory Muscle in Patient With Pulmonary Arterial Hypertension patient assessment - Pulmonary Artery Hypertension | Completed | Giresun University | 52 | 2021-09-09 | 2022-06-01 | |
| Assessing the Repeatability of NT-proBNP Testing Using Laboratory and Point of Care Testing in PAH Exercise group - Pulmonary Artery Hypertension | Completed | Sheffield Teaching Hospitals NHS Foundation Trust | 40 | 2021-02-19 | 2023-08-14 | |
| Right Ventricular Pacing in Pulmonary Arterial Hypertension Temporary right ventricular pacing - Pulmonary Artery Hypertension, Right Ventricular Dysfunction | Not applicable | Recruiting | University of California, San Francisco | 16 | 2021-01-01 | 2026-09-02 |
| GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH) GB002 (seralutinib), Placebo, Generic Dry Powder Inhaler - Pulmonary Artery Hypertension | Phase 2 | Completed | GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc. | 86 | 2020-11-12 | 2023-11-07 |
| Skeletal Muscle Mitochondrial Abnormalities and the Metabolic Syndrome in PAH Pulmonary Artery Hypertension | Completed | Laval University | 30 | 2019-06-01 | 2023-04-18 | |
| Cardiac Assessment by PV Loop in IPAH and Scleroderma PAH Scleroderma, Pulmonary Artery Hypertension | Completed | Johns Hopkins University | 43 | 2019-04-15 | 2026-01-09 | |
| Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension Metformin, Placebo, mHealth Intervention - Pulmonary Artery Hypertension | Phase 2 | Completed | Vanderbilt University Medical Center | 73 | 2018-08-23 | 2026-09-16 |
| Impact of Aerobic Training on Sleep Quality and Aerobic Fitness in Male Patients With Pulmonary Artery Hypertension Moderate intensity aerobic training - Pulmonary Artery Hypertension | Not applicable | Completed | Cairo University | 30 | 2018-06-02 | 2020-04-08 |
| Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires MRI Heart guidewire catheterization - Pulmonary Artery Hypertension, Congenital Heart Disease | Not applicable | Terminated | National Heart, Lung, and Blood Institute (NHLBI) | 22 | 2017-08-02 | 2026-07-15 |
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Familial Primary Pulmonary Hypertension (30) · Hypertension, Pulmonary (5) · Hypoxia (4) · Altitude Sickness (3) · Pulmonary Arterial Hypertension (2) · Pulmonary Disease, Chronic Obstructive (2) · Blood Coagulation Disorders (1) · Dyspnea (1) · Heart Defects, Congenital (1) · Heart Failure (1) · Hepatitis C, Chronic (1) · Hernias, Diaphragmatic, Congenital (1) · Hypertension (1) · Insulin Resistance (1) · Lung Diseases (1)
Respiratory Tract Diseases (30) · Lung Diseases (29) · Hypertension, Pulmonary (25) · Cardiovascular Diseases (9) · Pathological Conditions, Signs and Symptoms (9) · Vascular Diseases (7) · Hypertension (5) · Signs and Symptoms (5) · Signs and Symptoms, Respiratory (5) · Respiration Disorders (4) · Chronic Disease (3) · Disease Attributes (3) · Heart Diseases (3) · Pathologic Processes (3) · Congenital Abnormalities (2)
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University of Zurich (5) · Bastiaan Driehuys (1) · Cairo University (1) · China National Center for Cardiovascular Diseases (1) · D. Walter Wray (1) · GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc. (1) · Giresun University (1) · Imperial College London (1) · Insel Gruppe AG, University Hospital Bern (1) · Johns Hopkins University (1) · Kantonsspital Olten (1) · Klinikum der Universität Köln (1) · Laval University (1) · Mayo Clinic (1) · National Heart, Lung, and Blood Institute (NHLBI) (1)
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PMID 28100544, PMID 29925397, PMID 31775708, PMID 33604801, PMID 38705167, PMID 39698150, PMID 40611611, PMID 41921908
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