35 completed, 17 unknown, 7 recruiting, 3 not yet recruiting. 29 Not applicable, 14 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 29 | Completed 12, Unknown 9, Not yet recruiting 3, Recruiting 3, Enrolling by invitation 1, Terminated 1 |
| Phase 4 | 14 | Completed 8, Unknown 4, Recruiting 2 |
| Phase 2 | 1 | Completed 1 |
Follow Propofol: new trials by email Literature Review of Propofol trials Research Report on Propofol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Propofol-Ketamine Versus Sevoflurane for Laryngeal Mask Anesthesia in Pediatric Cardiac Catheterization Ketamine-Propofol, Sevoflurane - Propofol, Ketamine | Phase 4 | Recruiting | Rawalpindi Institute of Cardiology | 68 | 2026-10-24 | 2026-10-30 |
| Remimazolam on the Incidence of Postoperative Acute Kidney Injury Remimazolam (Byfavo), propofol - Remimazolam, Propofol | Not applicable | Not yet recruiting | Seoul National University Bundang Hospital | 78 | 2026-06-26 | 2026-06-29 |
| Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients induction type for intubation in ICU - Critically Ill, Intubation Complication | Completed | Zeliha Alicikus | 806 | 2026-04-18 | 2026-10-08 | |
| Personalized Music and Dreaming During Propofol Sedation Preferred Music, Matched Non-Preferred Music, Silence (Headphones Only) - Conscious Sedation, Propofol | Not applicable | Completed | Wonkwang University Hospital | 300 | 2025-12-19 | 2026-10-02 |
| Minto and Eleveld Remifentanil Target Controlled Infusion (TCI) Models: a Clinical Comparison Propofol, Anesthesia Brain Monitoring | Recruiting | University of Padova | 100 | 2025-11-25 | 2026-06-08 | |
| Robotic-assisted Bronchoscopy Under Moderate Sedation With Propofol Robotic-assisted bronchoscopy under propofol - Lung Lesions, Robotic Assisted Bronchoscopy | Not applicable | Terminated | University of Zurich | 10 | 2025-08-14 | 2026-07-24 |
| Comparison of Sevoflurane and Propofol on ANI propofol, Sevoflurane - Propofol, Sevoflurane | Not applicable | Not yet recruiting | Pusan National University Yangsan Hospital | 30 | 2025-06-30 | 2025-06-10 |
| The Effect of General Anesthesia with Remimazolam and Propofol on Rhythmic State and Cognitive Function Remimazolam, propofol - Cognitive Functioning, Propofol | Not applicable | Not yet recruiting | The Second Affiliated Hospital of Chongqing Medical University | 174 | 2025-02-24 | 2025-02-14 |
| Comparison of Ciprofol and Propofol Under IoC1 and IoC2 Monitoring for Adenotonsillectomy Ciprofol group, Propofol group - Adenotonsillectomy, Propofol | Not applicable | Recruiting | Maternal and Child Health Hospital of Hubei Province | 236 | 2025-02-22 | 2025-06-12 |
| Remimazolam Besylate in Sedation of Postcardioperative Patients Remimazolam, Propofol - Remimazolam, Propofol | Not applicable | Recruiting | First Affiliated Hospital of Zhejiang University | 120 | 2025-02-10 | 2025-02-18 |
| Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Hysterectomy Propofol, Sevoflurane plus lidocaine infusion, Sevoflurane - Sevoflurane, Lidocaine | Not applicable | Recruiting | Tanta University | 90 | 2025-02-01 | 2025-07-14 |
| Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation Dexmedetomidine-Propofol, Ketamine-Propofol - Propofol | Not applicable | Completed | Sohag University | 100 | 2024-11-12 | 2026-05-27 |
| Sedation With Dexmedetomidine or Midazolam in Combination With Propofol for Removal of Double-J Ureteral Stent Propofol, Propofol and Dexmedetomidine, Propofol and Midazolam - Sedation, Dexmedetomidine | Not applicable | Completed | Tanta University | 60 | 2024-11-01 | 2026-05-12 |
| RCT Comparing Remimazolam With Propofol Under EEG DSA Guidance During Cardiac Electrophysiology Studies and Ablation Propofol, Remimazolam, With intubation and controlled ventilation to maintain airway - Hemodynamic, Remimazolam | Not applicable | Enrolling by invitation | Taipei Veterans General Hospital, Taiwan | 200 | 2024-09-20 | 2024-11-22 |
| Propofol-related Euphoria in Pain-free Gastrointestinal Endoscopy Patients Propofol, Addictive Behaviors | Completed | Northern Jiangsu People's Hospital | 986 | 2024-09-18 | 2025-12-08 | |
| Virtual Reality for Anxiolysis and Pharmacological Sparing Virtual reality headset, Standard of care - Virtual Reality, Propofol | Not applicable | Unknown | Ciusss de L'Est de l'Île de Montréal | 100 | 2024-09-01 | 2024-07-26 |
| Additive Effects of Clonidine Used in Propofol Sedation in Colonoscopy Propofol, Propofol combined with clonidine - Clonidine, Propofol | Not applicable | Unknown | Tanta University | 62 | 2024-07-20 | 2024-07-23 |
| Sevoflurane Versus Propofol: Effect on Stress Response taking blood sample - Propofol, Sevoflurane | Completed | Dr. Lutfi Kirdar Kartal Training and Research Hospital | 40 | 2024-05-23 | 2024-08-09 | |
| Investigating Near-Threshold Perception During Anesthetic Sedation Functional Magnetic Resonance Imaging (fMRI) with propofol - Propofol, Anesthesia | Phase 2 | Completed | University of Michigan | 40 | 2024-05-10 | 2026-10-30 |
| Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring Propofol-Fentanyl, Propofol-Fentanyl-Dexmedetomidine, Propofol-Fentanyl-Sevoflurane - Propofol, Fentanyl | Not applicable | Completed | Ain Shams University | 78 | 2024-01-20 | 2025-12-22 |
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Anxiety Disorders (2) · Emergence Delirium (2) · Hypotension (2) · Acute Kidney Injury (1) · Alcohol Drinking (1) · Apnea (1) · Atrial Fibrillation (1) · Behavior, Addictive (1) · Breast Neoplasms (1) · Critical Illness (1) · Delirium (1) · Depression (1) · Dyssomnias (1) · Facial Expression (1) · Glioma (1)
Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (9) · Neurologic Manifestations (7) · Mental Disorders (6) · Nervous System Diseases (5) · Behavior (4) · Pathologic Processes (4) · Cardiovascular Diseases (3) · Confusion (3) · Neurobehavioral Manifestations (3) · Neurocognitive Disorders (3) · Delirium (2) · Neoplasms (2) · Postoperative Complications (2) · Signs and Symptoms, Respiratory (2)
Propofol (36) · Dexmedetomidine (10) · remimazolam (10) · Sevoflurane (8) · Intubation (2) · Midazolam (2) · Sufentanil (2) · cisatracurium (2) · (2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol (1) · Aminophylline (1) · Anesthetics (1) · Anesthetics, Intravenous (1) · Blood Specimen Collection (1) · Clonidine (1) · Desflurane (1)
Tanta University (4) · University of Padova (3) · Ankara City Hospital Bilkent (2) · Asan Medical Center (2) · Beijing Tiantan Hospital (2) · Menoufia University (2) · Second Affiliated Hospital of Nanchang University (2) · Seoul National University Bundang Hospital (2) · Ain Shams University (1) · Atlantic Center for Oral and Maxillofacial Surgery (1) · Azienda Sanitaria-Universitaria Integrata di Udine (1) · Bezmialem Vakif University (1) · Chonnam National University Hospital (1) · Ciusss de L'Est de l'Île de Montréal (1) · DongGuk University (1)
China (18) · Egypt (8) · South Korea (8) · Italy (5) · Switzerland (3) · Taiwan (3) · Turkey (Türkiye) (3) · Belgium (2) · Canada (2) · United States (2) · Chile (1) · Germany (1) · India (1) · Pakistan (1) · Sweden (1)
Ben Davis, DDS FRCD(C) (1) · Cheol Lee, M.D.,Ph.D (1) · Feng-Fang Tsai, M.D. (1) · Gang Y Hao (1) · Gil Gavel (1) · Goverdhan D Puri, MD, PhD (1) · Helena Matus, MD (1) · Helge Servatius, MD (1) · Hyo-Seok Na, MD, PhD (1) · Hyunjung Lee, MD, Master (1) · Jayashree Sood, MD, FFRCA, PGDHHM, FICA (1) · Jeongil Choi, MD, PhD (1) · Ji Zhu, Ph.D (1) · Jiang Hong, Ph.D (1)
PMID 10825339, PMID 15500495, PMID 18072987, PMID 19713256, PMID 19845550, PMID 21903640, PMID 22436955, PMID 23748199, PMID 24891132, PMID 28873076, PMID 30286006, PMID 32445415, PMID 34584543, PMID 34950101, PMID 35056370, PMID 36682527, PMID 39038404, PMID 39085782, PMID 40348954, PMID 40514628, PMID 40622954, PMID 40771463, PMID 42129719
2018 (1), R01GM103894 (1)