139 completed, 65 recruiting, 45 unknown, 19 active not recruiting. 300 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 300 | Completed 139, Recruiting 65, Unknown 45, Active not recruiting 19, Not yet recruiting 12, Withdrawn 8, Terminated 6, Enrolling by invitation 5, Suspended 1 |
Follow Primary Dysautonomias: new trials by email Literature Review of Primary Dysautonomias trials Research Report on Primary Dysautonomias
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Impact of Improved Vagal Function on Periaqueductal Gray Connectivity breathing exercise training - Postural Tachycardia Syndrome | Not applicable | Not yet recruiting | Virginia Commonwealth University | 12 | 2028-01-01 | 2026-09-16 |
| Cardiovascular Autonomic Function After Resistance Training Upper-Limb Resistance Training - Spinal Cord Injury | Not applicable | Not yet recruiting | Pusan National University Yangsan Hospital | 20 | 2026-10-01 | 2026-09-03 |
| RESET-POTS: Multimodal Phenotyping and Stellate Ganglion Block in Postural Orthostatic Tachycardia Syndrome Bilateral Sequential Stellate Ganglion Block - POTS - Postural Orthostatic Tachycardia Syndrome | Not applicable | Not yet recruiting | University Medical Centre Ljubljana | 30 | 2026-10-01 | 2026-09-24 |
| aVNT in POTS - Pilot active aVNT vs. Sham - Postural Orthostatic Tachycardia Syndrome (POTS) | Not applicable | Not yet recruiting | University of Calgary | 30 | 2026-09-01 | 2026-05-01 |
| Impact of Transcutaneous Spinal Stimulation on Blood Pressure and Orthostasis in Spinal Cord Injury Tilt test with stimulation (real-time effects): Intervention 1, 20 sessions of stimulation (Intervention 2) - Spinal Cord Injuries, Hypotension | Not applicable | Not yet recruiting | Kessler Foundation | 10 | 2026-09-01 | 2026-06-29 |
| Non-invasive Vagus Nerve Stimulation for Chronic Musculoskeletal Pain Active Vagus Nerve Stimulation, Subtherapeutic Stimulation (Sham Control) - Chronic Musculoskeletal Pain, Autonomic Dysfunction | Not applicable | Not yet recruiting | University of Leeds | 12 | 2026-05-14 | 2026-05-11 |
| Repetitive Transcranial Magnetic Stimulation in Cardiac Autonomic Dysfunction rTMS M1 Motor Cortex Protocol, Sham rTMS Protocol - Stroke, Autonomic Dysfunction | Not applicable | Recruiting | Afyonkarahisar Health Sciences University | 44 | 2026-03-26 | 2026-06-25 |
| Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease Whole-body Electrical Muscle Stimulation Exercise - Neuromuscular Diseases (NMD), Amyotrophic Lateral Sclerosis | Not applicable | Recruiting | University of Missouri-Columbia | 50 | 2026-03-10 | 2026-03-17 |
| Is Swimming a More Tolerable Form of Movement for Individuals With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome? Swimming, Cycling - ME/CFS, Long COVID | Not applicable | Suspended | Simon Fraser University | 50 | 2026-02-20 | 2026-03-30 |
| Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders UHR PET/CT scan of the brain with ¹⁸F-FDG, UHR PET/CT scan of the brain with ¹⁸F-PE2I, UHR PET/CT scan of the brain with ¹⁸F-SynVesT-1 - Alzheimer Dementia (AD), ALS - Amyotrophic Lateral Sclerosis | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 300 | 2026-02-13 | 2026-04-03 |
| Individualized Transcranial Magnetic Stimulation in Parkinsonian Disorders TMS - Parkinson's Disease, Multiple System Atrophy | Not applicable | Recruiting | Peking University First Hospital | 50 | 2025-12-22 | 2026-06-29 |
| HIIT for Inflammatory-driven Shoulder Pain. High intensity interval training (HIIT) - Chronic Shoulder Pain, Rotator Cuff Related Shoulder Pain | Not applicable | Recruiting | Universiteit Antwerpen | 30 | 2025-12-10 | 2026-02-13 |
| The Effects of Inspiratory Muscle Training Female Patients With Fibromyalgia Exercise - Fibromyalgia, Autonomic Dysfunction | Not applicable | Not yet recruiting | Nigde Omer Halisdemir University | 51 | 2025-12-05 | 2025-12-03 |
| Long COVID Diagnostic Reactivity Assesment Test Electrodiagnostic Bioelectrical Assessment - Long COVID, Post-Acute Sequelae of SARS-CoV-2 Infection | Not applicable | Enrolling by invitation | Oncology Center,Ministry Of Heath,Uzbekistan | 50 | 2025-12-05 | 2026-01-15 |
| Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity Increase of physical activity volume and intensity with the use of a motivational smartphone application - Parkinson Disease, Prodromal Stage | Not applicable | Recruiting | University Hospital, Bonn | 130 | 2025-12-04 | 2026-01-16 |
| Assesment of the Clinical Benefit of Provocation on Tilt-table in SYNCope Patients, TiltSYNC-trial biofeedback and standard of care with tilt table testing, no tilt table testing - Vasovagal Syncope (VVS) | Not applicable | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 238 | 2025-10-30 | 2026-03-11 |
| Ultrasound Guided Stellate Ganglion Block in Postural Tachycardia Syndrome Stellate ganglion block, Sham injection of saline, Ropivacaine - Postural Tachycardia Syndrome | Not applicable | Recruiting | Stanford University | 20 | 2025-10-16 | 2026-10-28 |
| SUBDIMA: Subclinical Depression in Acute Myocardial Infarction (SUBDIMA25) Psychological, Cognitive, and Patient-Reported Outcome Assessments - Acute Myocardial Infarction, Subclinical Depression | Not applicable | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 100 | 2025-10-14 | 2026-09-04 |
| Programming Aquatic Therapy for POTS Aquatic Occupational Therapy - Postural Orthostatic Tachycardia Syndrome (POTS) | Not applicable | Completed | California State University, Dominguez Hills | 5 | 2025-09-12 | 2026-04-03 |
| NightWare and Cardiovascular Health in Veterans With PTSD NightWare - Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases | Not applicable | Recruiting | VA Office of Research and Development | 125 | 2025-09-10 | 2026-10-08 |
Showing 20 of 300. Sign in to see all of them.
Postural Orthostatic Tachycardia Syndrome (64) · Hypotension, Orthostatic (60) · Multiple System Atrophy (49) · Syncope, Vasovagal (40) · Parkinson Disease (35) · Orthostatic Intolerance (24) · Syncope (24) · Spinal Cord Injuries (23) · Post-Exercise Hypotension (21) · Hypertension (19) · Pure Autonomic Failure (17) · Motor Activity (16) · Autonomic Nervous System Diseases (15) · Supranuclear Palsy, Progressive (15)
Nervous System Diseases (294) · Autonomic Nervous System Diseases (285) · Orthostatic Intolerance (163) · Pathological Conditions, Signs and Symptoms (139) · Signs and Symptoms (119) · Cardiovascular Diseases (110) · Neurologic Manifestations (109) · Vascular Diseases (106) · Central Nervous System Diseases (96) · Brain Diseases (79) · Hypotension (78) · Basal Ganglia Diseases (68) · Movement Disorders (66) · Neurodegenerative Diseases (66)
Exercise (13) · Blood Specimen Collection (4) · Midodrine (4) · Physical Therapy Modalities (4) · Saline Solution (4) · Vagus Nerve Stimulation (4) · Deep Brain Stimulation (3) · Lower Body Negative Pressure (3) · Sodium Chloride (3) · Transcutaneous Electric Nerve Stimulation (3) · Breathing Exercises (2) · Exercise Test (2) · Head-Down Tilt (2) · High-Intensity Interval Training (2) · Metoprolol (2)
University of Calgary (11) · Vanderbilt University (10) · Vanderbilt University Medical Center (10) · Wake Forest University Health Sciences (9) · University Hospital, Bordeaux (6) · VA Office of Research and Development (6) · Centre of Postgraduate Medical Education (5) · University Hospital, Toulouse (5) · University of British Columbia (5) · University of Colorado, Denver (5) · Kessler Foundation (4) · Mayo Clinic (4) · Simon Fraser University (4) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (3) · Hospital de Clinicas de Porto Alegre (3)
United States (122) · Canada (28) · France (20) · Italy (12) · Brazil (11) · United Kingdom (11) · Spain (9) · China (7) · Germany (7) · Poland (7) · Denmark (6) · Sweden (6) · Austria (5) · Belgium (5) · Netherlands (5)
Italo Biaggioni, MD (9) · Satish R Raj, MD MSCI (9) · Charles Tegeler, MD (4) · Alberto Benussi, MD (3) · Alfredo J Gamboa, MD (3) · Barbara Borroni, MD (3) · Charles H Tegeler, MD (3) · Horacio Kaufmann, MD (3) · Satish R Raj, MD, MSCI (3) · Victoria E Claydon, PhD (3) · Andrei Krassioukov, MD,PhD,FRCPC (2) · Franca Barbic, MD (2) · Gail F Forrest, PhD (2) · Jill Wecht, EdD (2) · Katja Karrento, MD (2)
PMID 15670960, PMID 21712276, PMID 36114133, PMID 22565936, PMID 30354289, PMID 38036236, PMID 19797151, PMID 22275485, PMID 26411271, PMID 27402231, PMID 29562304, PMID 30338504, PMID 31330187, PMID 31439288, PMID 33279955, PMID 33739123, PMID 11146266, PMID 11210997, PMID 11231036, PMID 12239256, PMID 12885750, PMID 15297344, PMID 15451153, PMID 15666063, PMID 15758011, PMID 16731474, PMID 17130304, PMID 17384373, PMID 17490754, PMID 17903630, PMID 18086659, PMID 18426998, PMID 18850311, PMID 19207753, PMID 19563367, PMID 19713422, PMID 19919966, PMID 20447621, PMID 20585013, PMID 21266211, PMID 21420883, PMID 21576131, PMID 21752826, PMID 22016786, PMID 22048993, PMID 22434334, PMID 22972872, PMID 23017648, PMID 23283362, PMID 23514202
R01HL102387 (4), 2008 (1), 2017 (1), I01CX002762 (1), I21RX004373 (1), IK1RX003706 (1), K23HD102663 (1), K23RR020783 (1), P01HL056693 (1), R01AG059613 (1), R01AR081382 (1), R01DK140255 (1), R01HL071784 (1), R01HL128393 (1), R01HL161095 (1)