223 completed, 98 unknown, 43 recruiting, 39 terminated. 450 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 450 | Completed 223, Unknown 98, Recruiting 43, Terminated 39, Withdrawn 22, Not yet recruiting 18, Active not recruiting 6, Suspended 1 |
Follow Pregnancy Complications: new trials by email Literature Review of Pregnancy Complications trials Research Report on Pregnancy Complications
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PREterm Infants With Bronchial Obstruction - Prospective Study of Efficacy and Safety of Inhaled Tiotropium tiotropium bromide (Spiriva Respimat) - Bronchial Obstruction, Premature Birth | Phase 4 | Not yet recruiting | General University Hospital, Prague | 50 | 2026-11-01 | 2026-09-18 |
| Effect of LMWH on Neonatal Outcomes in Isolated Oligohydramnios Enoxaparin (LMWH), Dextrose Water - Oligohydramnios, Heparin | Phase 4 | Recruiting | PAEC General Hospital, Islamabad | 106 | 2026-10-24 | 2026-10-30 |
| Azithromycin for Cerclage Prophylaxis Azithromycin Prophylaxis, Azithromycin Placebo, Cefazolin - Cervical Insufficiency | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 80 | 2026-10-15 | 2026-10-27 |
| Dexamethasone Versus Ondansetron for Preventing Post-Spinal Hypotension in Preeclampsia Dexamethasone, Ondansetron - Preeclampsia, Spinal Anesthesia-Induced Hypotension | Phase 4 | Not yet recruiting | Assiut University | 110 | 2026-10-01 | 2026-08-31 |
| Biomarkers in Management of Post Partum Preeclampsia Magnesium Sulfate - Preeclampsia Severe, Preeclampsia Postpartum | Phase 4 | Not yet recruiting | Alexander Harrison | 100 | 2026-09-01 | 2026-09-09 |
| Fentanyl and Rocuronium for Tracheal Intubation in Newborns Rocuronium Bromide 10 MG/ML, Fentanyl 1 mcg/kg IV, single dose, administered before non-emergent tracheal intubation. - Infant, Premature, Intubation, Intratracheal | Phase 4 | Not yet recruiting | UEA - Universidade Do Estado Do Amazonas | 102 | 2026-09-01 | 2026-07-01 |
| Progesterone Preeclampsia Progesterone supplementation - Preeclampsia, Hypertensive Disorder of Pregnancy | Phase 4 | Recruiting | Medical University of South Carolina | 642 | 2026-08-13 | 2026-08-17 |
| Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial Carbetocin, Oxytocin, Placebo Saline Infusion - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Recruiting | Mansoura University | 332 | 2026-08-08 | 2026-10-09 |
| Impact of Higher Zinc Supplementation on Neonatal Weight Velocity 1 mg/day Zinc Supplementation, 3 mg/day Zinc Supplementation - Extreme Prematurity,Extremely Low Birthweight, BPD - Bronchopulmonary Dysplasia | Phase 4 | Recruiting | Augusta University | 30 | 2026-08-01 | 2026-10-26 |
| Oxytocin Bolus Versus Infusion in High-Risk Patients Undergoing Elective Cesarean Section (INBOX-HR) Oxytocin Bolus or Oxytocin Infusion - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Not yet recruiting | Stony Brook University | 180 | 2026-08-01 | 2026-08-03 |
| A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia Norethindrone 0.35 MG, Drospirenone - Hypertension, Preeclampsia | Phase 4 | Not yet recruiting | Oregon Health and Science University | 50 | 2026-07-01 | 2025-12-19 |
| PROMab Trial: Ampicillin With or Without Gentamicin for Term Prelabour Rupture of Membranes Ampicillin, Ampicillin + gentamicin - Rupture of Membranes Prior to Onset of Labor | Phase 4 | Not yet recruiting | Sarawak General Hospital | 320 | 2026-07-01 | 2026-05-04 |
| Optimizing Preeclampsia Postpartum With Point-of-care Ultrasound Butterfly iQ3 ultrasound system for determination of postpartum volume status, Oral furosemide, Intravenous furosemide - Preeclampsia, Preeclampsia Postpartum | Phase 4 | Not yet recruiting | University of California, Irvine | 96 | 2026-06-15 | 2026-01-23 |
| Intranasal Esketamine-dexmedetomidine Combination and Postpartum Depression Esketamine-dexmedetomidine combination, Placebo - Parturients, Depressive Symptoms | Phase 4 | Not yet recruiting | Peking University First Hospital | 164 | 2026-06-01 | 2026-06-15 |
| Vitamin D Supplementation Among Pregnant Women in Uganda for the Prevention of Hypertensive Disorders in Pregnancy, and Other Adverse Maternal and Foetal Outcomes oral 2.000 IU vitamin D3 (cholecalciferol) daily, in addition to routine ANC supplementations, Placebo - Preeclampsia, Eclampsia | Phase 4 | Not yet recruiting | St Mary's Hospital, Lacor | 1980 | 2026-06-01 | 2026-04-03 |
| Comparison of High- Versus Low-Dose Aspirin for Pregnancy Outcomes in Women at High Risk of Preeclampsia Aspirin - Preeclampsia | Phase 4 | Recruiting | Medicare Hospital (Pvt) Limited | 60 | 2026-05-12 | 2026-08-21 |
| Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum Hemorrhage Carbetocin, Oxytocin - Postpartum Hemorrhage, Twin Pregnancy | Phase 4 | Recruiting | Sheba Medical Center | 120 | 2026-05-05 | 2026-05-08 |
| Comparison of Metformin Versus Glyburide for Blood Sugar Control in Women With Gestational Diabetes Metformin, Glyburide - Gestational Diabetes Mellitus (GDM) | Phase 4 | Recruiting | Nishtar Medical University | 92 | 2026-04-18 | 2026-09-03 |
| Vitality in Infants Via Azithromycin for Neonates Trial Azithromycin at Baseline, Azithromycin at Day 21, Placebo at Baseline - Neonatal Death, Infectious Disease | Phase 4 | Not yet recruiting | University of California, San Francisco | 4000 | 2026-04-01 | 2025-08-29 |
| A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask - Overactive Bladder, Neurogenic Bladder | Phase 4 | Not yet recruiting | TriHealth Inc. | 96 | 2026-02-01 | 2026-02-04 |
Showing 20 of 450. Sign in to see all of them.
Premature Birth (118) · Pre-Eclampsia (68) · Postpartum Hemorrhage (59) · Diabetes, Gestational (33) · Hypertension, Pregnancy-Induced (26) · Obstetric Labor, Premature (24) · Abortion, Spontaneous (14) · Depression, Postpartum (14) · Fetal Membranes, Premature Rupture (14) · Abortion, Habitual (13) · Uterine Inertia (13) · Hypertension (12) · Abortion, Missed (11) · Fetal Growth Retardation (9)
Female Urogenital Diseases and Pregnancy Complications (450) · Urogenital Diseases (450) · Obstetric Labor Complications (214) · Pathological Conditions, Signs and Symptoms (135) · Obstetric Labor, Premature (110) · Pathologic Processes (102) · Puerperal Disorders (79) · Uterine Hemorrhage (59) · Hemorrhage (54) · Hypertension, Pregnancy-Induced (51) · Cardiovascular Diseases (48) · Nutritional and Metabolic Diseases (46) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (45) · Metabolic Diseases (40)
Misoprostol (33) · Oxytocin (24) · Aspirin (20) · Metformin (20) · Progesterone (20) · Saline Solution (19) · Sodium Chloride (17) · carbetocin (17) · Nifedipine (16) · Tranexamic Acid (12) · Ibuprofen (10) · Magnesium Sulfate (9) · Insulin (8) · Mifepristone (8) · Dexamethasone (7)
Cairo University (14) · Assiut University (13) · Gynuity Health Projects (8) · Ain Shams University (7) · Ohio State University (7) · Assistance Publique - Hôpitaux de Paris (6) · Instituto Materno Infantil Prof. Fernando Figueira (6) · The University of Texas Health Science Center, Houston (6) · Woman's Health University Hospital, Egypt (6) · Zekai Tahir Burak Women's Health Research and Education Hospital (6) · Hospital de Clinicas de Porto Alegre (5) · Mohamed Sayed Abdelhafez (5) · Nishtar Medical University (5) · Beni-Suef University (4) · Brigham and Women's Hospital (4)
United States (113) · Egypt (63) · France (22) · China (20) · Brazil (19) · Israel (16) · Canada (15) · Pakistan (15) · Italy (13) · India (10) · Turkey (Türkiye) (10) · Spain (9) · Netherlands (7) · Thailand (7) · United Kingdom (7)
Mohamed S Abdelhafez, Dr (5) · Ahmed Maged (4) · Alaa M Ismail, M D (4) · Vorapong Phupong, M.D. (4) · Waleed El-refaie, Dr (4) · Ahmed Maged, MD (3) · Hillary Bracken, PhD (3) · Maisa N Feghali, MD (3) · Ricardo F Savaris, MD, PhD (3) · Ahmed M Badawy, Prof (2) · Alisse K Hauspurg, MD (2) · Assaf Ben-Meir, MD (2) · Beverly Winikoff, MD, MPH (2)
PMID 37815037, PMID 35947046, PMID 27640943, PMID 28657417, PMID 29588190, PMID 29939940, PMID 34061352, PMID 34932836, PMID 36996264, PMID 41114449, PMID 10649166, PMID 11052579, PMID 11057854, PMID 12710654, PMID 12738159, PMID 14711847, PMID 14719181, PMID 15105384, PMID 15500369, PMID 15585684, PMID 16108235, PMID 16254497, PMID 16293412, PMID 16309682, PMID 16632649, PMID 16882832, PMID 16934269, PMID 17012482, PMID 17027730, PMID 17431740, PMID 17564958, PMID 17636190, PMID 18008241, PMID 18226126, PMID 18275573, PMID 18765009, PMID 19047225, PMID 19074961, PMID 19445547, PMID 19562567, PMID 19571170, PMID 19617208, PMID 19656148, PMID 19786331, PMID 1979363, PMID 19812173, PMID 19881390, PMID 19902266, PMID 19941706, PMID 19956811
2009 (2), 2016 (2), 2018 (2), 2019 (2), 2023 (2), 2005 (1), 2014 (1), 2015 (1), 2017 (1), K12HD001258 (1), K23HD092893 (1), K23HL168356 (1), R01HD097578 (1), R21HD090987 (1), R21MH063242 (1)