52 completed, 15 unknown, 10 terminated, 4 recruiting. 86 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 86 | Completed 52, Unknown 15, Terminated 10, Recruiting 4, Not yet recruiting 2, Withdrawn 2, Active not recruiting 1 |
Follow Pregnancy: new trials by email Literature Review of Pregnancy trials Research Report on Pregnancy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Once-Daily vs Twice-Daily Insulin Glargine in Pregestational Diabetes Management Use of insulin glargine once daily, Use of insulin glargine twice daily - Pregestational Diabetes, Pregnancy | Phase 4 | Recruiting | Eastern Virginia Medical School | 200 | 2026-05-18 | 2026-05-15 |
| Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean Section Intrathecal Morphine, TAP Block - Pregnancy, Cesarean Section | Phase 4 | Not yet recruiting | Istituto Giannina Gaslini | 100 | 2026-03-01 | 2026-01-30 |
| Concurrent Versus Sequential Administration of Tdap and RSV Vaccines in Pregnancy Tdap Vaccine Administration, RSV Vaccine, Saline (as a placebo) - RSV, Tdap - Tetanus, Diphtheria and Acellular Pertussis Vaccination | Phase 4 | Recruiting | Canadian Immunization Research Network | 60 | 2025-10-16 | 2026-10-22 |
| AI-POCUS for Maternal and Neonatal Health in Ethiopia AI-POCUS (BabyChecker, Delft Imaging), AI-POCUS (Edan, China) - Pregnancy, Pregnancy Complications | Phase 4 | Not yet recruiting | Tsinghua University | 1059 | 2025-09-30 | 2025-09-12 |
| Efficacy and Safety of Low-dose Calcium Supplementation in Pregnancy Calcium - Pregnancy | Phase 4 | Completed | First People's Hospital of Hangzhou | 117 | 2025-09-10 | 2026-08-25 |
| Vitamin D for Preventing Recurrent Preeclampsia in Pregnant Women Vitamin D, Placebo and standard of care - Pre-eclampsia, Pregnancy | Phase 4 | Recruiting | Nishtar Medical University | 146 | 2025-08-09 | 2025-12-17 |
| Oral Iron Supplementation on Alternate vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy daily ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill, alternate day ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill - Iron-deficiency Anemia (IDA), Pregnancy | Phase 4 | Recruiting | Southern Illinois University | 120 | 2025-05-27 | 2026-04-24 |
| Comparing Intravenous and Intramuscular Magnesium Sulphate for Preventing Seizure Recurrence in Women With Eclampsia Magnesium Sulphate infusion, Magnesium sulphate intramuscular - Eclampsia, Seizures | Phase 4 | Completed | Nishtar Medical University | 200 | 2025-05-13 | 2025-12-15 |
| Ferric Carboxymaltose Versus Iron Sucrose for Treating Anemia in Pregnant Women Iron Carboxymaltose, Iron Sucrose Injection - Iron Deficiency Anemia (IDA), Pregnancy | Phase 4 | Completed | CMH Multan Institute of Medical Sciences | 60 | 2024-02-01 | 2025-04-06 |
| Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics Malaria High-Sensitivity Rapid Diagnostic Test (HS-RDT), Artemether-lumefantrine (AL) - Malaria,Falciparum, Malaria in Pregnancy | Phase 4 | Active not recruiting | Duke University | 2174 | 2023-11-06 | 2026-10-30 |
| The Effect of Low-dose Atropine on Sympathetic Blockade in Spinal Cesarean Section Patients Slow dose preemptive Atropine, Ephedrine - Pregnancy, Cesarean Section | Phase 4 | Completed | Abant Izzet Baysal University | 60 | 2023-07-19 | 2023-10-11 |
| Evaluate Efficacy Levobupivacaine 0.125% Versuss Ropivacaine 0.2% in Hemodynamic Alterations in Labor and Fetal Repercussions Levobupivacaine, Ropivacaine - Hemodynamic Instability, Epidural | Phase 4 | Unknown | Althaia Xarxa Assistencial Universitària de Manresa | 40 | 2023-06-01 | 2023-05-26 |
| Gastric Volumes by US in Term Parturients Undergoing CS With and Without Metoclopramide Study drug metoclopramide, Study drug placebo administration - Pregnancy, Cesarean Section | Phase 4 | Completed | Northwestern University | 72 | 2021-10-20 | 2025-09-11 |
| RCT of Epinephrine (None, 100mcg, and 200mcg) in a Hyperbaric Bupivacaine, Fentanyl and Morphine Spinal in C-sections. 100 mcg Epinephrine, normal saline, 200 mcg Epinephrine - Pregnancy, Cesarean Section | Phase 4 | Withdrawn | University of Florida | 2019-10-01 | 2019-11-25 | |
| Study on the Mechanism of Colla Corri Asini in the Treatment of Thalassemia Patients With Pregnancy Anemia Colla corii asini - Thalassemia, Pregnancy | Phase 4 | Unknown | The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine | 70 | 2017-12-01 | 2018-01-16 |
| A Comparison of Oral Misoprostol and Vaginal Misoprostol for Cervical Ripening and Induction of Labor Misoprostol - Labor; Forced or Induced, Affecting Fetus or Newborn, Pregnancy | Phase 4 | Terminated | Milton S. Hershey Medical Center | 34 | 2017-11-01 | 2022-10-13 |
| Tenofovir As Prevention Of Hepatitis b Mother-to-child Transmission Tenofovir disoproxil fumarate, Rapid tests HBe Ag - Hepatitis B Chronic Infection, Pregnancy | Phase 4 | Unknown | ANRS, Emerging Infectious Diseases | 933 | 2017-10-04 | 2019-10-16 |
| Kerlix for Pregnant Women With Elevated BMI to Prevent Wound Infection by 6 Weeks Post Partum Kerlix-AMD, placebo--normal gauze - Obesity, Wound Infection | Phase 4 | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 40 | 2016-10-01 | 2016-08-29 |
| Safety and Immunogenicity of Simultaneous Tdap and IIV in Pregnant Women Tetanus, Diphtheria, and Pertussis Vaccine, 2016-2017 Quadrivalent Inactivated Influenza Vaccine, 2017-2018 Quadrivalent Inactivated Influenza Vaccine - Pregnancy | Phase 4 | Completed | Duke University | 81 | 2016-09-01 | 2025-07-28 |
| Comparison of Vaginal Misoprostol Plus Supracervical Balloon Versus Vaginal Misoprostol Alone for Induction of Labor Misoprostol, Foley catheter - Induction of Labor, Cervical Ripening | Phase 4 | Unknown | Consorci Sanitari de Terrassa | 80 | 2016-05-01 | 2016-05-12 |
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Obesity (5) · Premature Birth (5) · Anemia, Iron-Deficiency (4) · Abortion, Spontaneous (2) · Behavior (2) · HIV Infections (2) · Hepatitis B, Chronic (2) · Hypotension (2) · Infections (2) · Infertility (2) · Malaria (2) · Nausea (2) · Pain (2) · Sexually Transmitted Diseases (2) · Stillbirth (2)
Pathological Conditions, Signs and Symptoms (23) · Urogenital Diseases (18) · Infections (14) · Female Urogenital Diseases and Pregnancy Complications (13) · Signs and Symptoms (13) · Pathologic Processes (11) · Pregnancy Complications (11) · Nutritional and Metabolic Diseases (9) · Genital Diseases (8) · Hematologic Diseases (7) · Hemic and Lymphatic Diseases (7) · Bacterial Infections (6) · Bacterial Infections and Mycoses (6) · Body Weight (6) · Neurologic Manifestations (6)
Misoprostol (6) · Bupivacaine (3) · Ephedrine (3) · Saline Solution (3) · Artemether, Lumefantrine Drug Combination (2) · Atropine (2) · Boostrix (2) · Clindamycin (2) · Clomiphene (2) · Emtricitabine (2) · Epinephrine (2) · Fentanyl (2) · Folic Acid (2) · Heparin (2) · Progesterone (2)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (4) · Duke University (3) · Karolinska Institutet (3) · Universitair Ziekenhuis Brussel (3) · Asian-Pacific Alliance of Liver Disease, Beijing (2) · Nishtar Medical University (2) · Northwestern University (2) · Oslo University Hospital (2) · The Hospital for Sick Children (2) · University of British Columbia (2) · University of Zurich (2) · Yazd Medical University (2) · AGUNCO Obstetrics and Gynecology Centre (1) · ANRS, Emerging Infectious Diseases (1) · Abant Izzet Baysal University (1)
United States (21) · Canada (8) · Italy (6) · Belgium (4) · Pakistan (4) · Brazil (3) · Iran (3) · Kenya (3) · United Kingdom (3) · China (2) · France (2) · India (2) · Norway (2) · Spain (2) · Switzerland (2)
Gideon Koren, MD (2) · Jun Cheng, M.D. (2) · Mehri Mashayekhy, infertility fellowship (2) · Abraham Katana, MD (1) · Akcan Akkaya, MD. (1) · Alan L Melnick, MD, MPH (1) · Alexander Krafft, MD (1) · Andrea Cornini, MD (1) · Andreas M Petersen, MD, PhD (1) · Arthur Leader, MD (1) · Bahaa Abu-Raya, M.D., PhD (1) · Baltazar Chilundo (1) · Beatriz J Grinsztejn, MD (1) · Bradley S Hurst, MD (1)
PMID 36996264, PMID 16394049, PMID 17540797, PMID 17714677, PMID 17888856, PMID 18313637, PMID 18360319, PMID 18395692, PMID 18450604, PMID 18468575, PMID 19187376, PMID 19245303, PMID 1945215, PMID 19664750, PMID 21514555, PMID 21843690, PMID 22927016, PMID 23020829, PMID 23396557, PMID 24405979, PMID 24417689, PMID 24549212, PMID 24590680, PMID 24614377, PMID 24922166, PMID 24999785, PMID 25127545, PMID 25254902, PMID 25344356, PMID 25713585, PMID 25817472, PMID 26164694, PMID 26165914, PMID 26258474, PMID 26275330, PMID 26327217, PMID 26340483, PMID 26429700, PMID 26542382, PMID 26691105, PMID 26872219, PMID 27038321, PMID 27142328, PMID 27297013, PMID 27310354, PMID 27338951, PMID 27485493, PMID 27724923, PMID 27745552, PMID 27879486
2015 (1), R01MH074394 (1), R01MH074399 (1), U01AI162463 (1), U01HD040477 (1)