391 completed, 231 unknown, 75 recruiting, 60 terminated. 190 Phase 4, 188 Phase 2, 146 Phase 1, 86 Not applicable, 85 Phase 3.
Follow Hepatitis B, Chronic: new trials by email Literature Review of Hepatitis B, Chronic trials Research Report on Hepatitis B, Chronic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| B-Ensure: Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants Bepirovirsen - Hepatitis B | Phase 4 | Not yet recruiting | GlaxoSmithKline | 303 | 2026-12-03 | 2026-11-02 |
| Targeting ANKRD11 Reverses HBV-Specific CD8+ T Cell Dysfunction and Tolerance Chronic Hepatitis B | Not yet recruiting | Beijing Municipal Administration of Hospitals | 40 | 2026-12-01 | 2026-08-28 | |
| Integrated Multi-Omics Analysis of Treatment-Naive Patients With Chronic HBV Infection Hepatitis B, Chronic | Not yet recruiting | Beijing Municipal Administration of Hospitals | 1000 | 2026-11-01 | 2026-11-13 | |
| A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB) AHB-137, Placebo, TVAX-008 - Chronic Hepatitis B | Phase 1 / Phase 2 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 105 | 2026-10-31 | 2026-10-19 |
| A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB) AHB-137, TVAX-008, Placebo - Chronic Hepatitis B | Phase 1 / Phase 2 | Not yet recruiting | Grand Theravac Life Sciences (Hangzhou) Co., Ltd. | 105 | 2026-10-31 | 2026-10-27 |
| Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Characteristics of ACT500 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Complicated With Chronic Hepatitis B ACT500 Tablets, ACT500 Placebo Tablets - Metabolic Dysfunction-associated Steatotic Liver Disease, Chronic Hepatitis b | Phase 1 | Not yet recruiting | Xiamen Amoytop Biotech Co., Ltd. | 24 | 2026-10-30 | 2026-09-14 |
| A Study of HT-101 and HT-102 in Chronic Hepatitis B (CHB) HT-101 + HT-102, HT-101 placebo + HT-102 placebo - Chronic Hepatitis B Virus Infection | Phase 2 | Not yet recruiting | Suzhou HepaThera Biotech Co., Ltd. | 120 | 2026-10-30 | 2026-11-05 |
| A Clinical Study of AHB-121 in Healthy Participants and Chronic Hepatitis B (CHB) Participants AHB-121, Placebo - Chronic Hepatitis B Virus | Phase 1 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 110 | 2026-10-28 | 2026-10-21 |
| Wearable Patch Ultrasound Probe for Diagnosis of Liver Stiffness Wearable Patch-Type Ultrasound Probe, Transient Elastography (FibroScan) - Liver Fibrosis, Liver Cirrhosis | Not yet recruiting | Second Affiliated Hospital of Xi'an Jiaotong University | 150 | 2026-10-01 | 2026-07-21 | |
| Phase Ia/Ib Trial of SCTA02A Injection in Healthy Adults and Patients With Chronic Hepatitis B SCTA02A, Placebo - Hepatitis B | Phase 1 | Not yet recruiting | Sinocelltech Ltd. | 60 | 2026-10-01 | 2026-10-29 |
| Prospective Evaluation of Hepatocellular Carcinoma Surveillance in At-Risk Patients (Screening HCC) Hepatocellular Carcinoma, Liver Cirrhosis | Not yet recruiting | D'Or Institute for Research and Education | 300 | 2026-09-15 | 2026-08-14 | |
| A Trial to Evaluate the Efficacy and Safety of WGc0201 in Patients With Chronic Hepatitis B Virus Infection WGc0201 - Chronic Hepatitis B Virus (Hbv) | Phase 1 | Recruiting | Jiyan Liu | 9 | 2026-09-01 | 2026-07-01 |
| Hepatitis B Infection Surveillance Chronic Hepatitis B Infection | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1360 | 2026-09-01 | 2026-07-27 | |
| Clinical Trial of TQA3605 Tablet in Combination With Nucleos(t)Ide Analogues(NAs) Versus NAs Alone for the Treatment of Patients With Chronic Hepatitis B Virus Infection Who Have Undergone Treatment and Exhibit Low Viral Load or Poor Response TQA3605 tablets Placebo, TQA3605 tablets, Entecavir dispersible tablets - Chronic Hepatitis B | Phase 3 | Not yet recruiting | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 930 | 2026-09-01 | 2026-10-02 |
| Sequential PD-1 Antibody and Pegylated Interferon Therapy for Nucleos(t)Ide Analogue-suppressed Chronic Hepatitis B Sintilimab, Pegylated Interferon-α 2b, Nucleos(t)ide Analogues - Chronic Hepatitis B | Not applicable | Not yet recruiting | Beijing 302 Hospital | 60 | 2026-09-01 | 2026-09-09 |
| Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions AHB-137 - Hepatitis B, Chronic | Phase 2 | Recruiting | AusperBio Therapeutics Inc. | 70 | 2026-09-01 | 2026-10-29 |
| HCC Risk Prediction Model Based on Multimodal Data in Chronic Hepatitis B No intervention (observational study) - Hepatocellular Carcinoma (HCC) | Not yet recruiting | Beijing Friendship Hospital | 2000 | 2026-08-20 | 2026-08-28 | |
| A Study on the Consistency Evaluation of Digital PCR Technology for Quantitative Detection of HBV Nucleic Acid the results were classified according to concentration levels - Chronic Hepatitis b | Not yet recruiting | Beijing Municipal Administration of Hospitals | 200 | 2026-08-01 | 2026-07-07 | |
| Study of GST-HG131&141 Tablets Compared With Placebo in Patients With Chronic Hepatitis B GST-HG141, GST-HG131, GST-HG141 Placebo - Chronic Hepatitis B | Phase 2 | Recruiting | Fujian Akeylink Biotechnology Co., Ltd. | 80 | 2026-07-10 | 2026-07-17 |
| A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function. AHB-137 injection - Chronic Hepatitis B | Phase 1 | Recruiting | Ausper Biopharma Co., Ltd. | 32 | 2026-07-09 | 2026-07-29 |
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