HIV Infections: Clinical Trials

5073 completed, 543 unknown, 322 terminated, 290 recruiting. 2014 Not applicable, 1260 Phase 1, 1147 Phase 2, 719 Phase 3, 571 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	2014	Completed 1480, Unknown 166, Recruiting 131, Active not recruiting 67, Terminated 60, Not yet recruiting 55, Withdrawn 36, Enrolling by invitation 15, Suspended 4
Phase 1	1260	Completed 1052, Terminated 62, Unknown 45, Withdrawn 39, Recruiting 28, Active not recruiting 20, Not yet recruiting 11, Suspended 2, Enrolling by invitation 1
Phase 2	1147	Completed 870, Terminated 88, Unknown 61, Withdrawn 51, Recruiting 33, Active not recruiting 22, Not yet recruiting 16, Suspended 6
Phase 3	719	Completed 573, Terminated 45, Unknown 45, Withdrawn 21, Active not recruiting 15, Recruiting 14, Not yet recruiting 4, Suspended 2
Phase 4	571	Completed 396, Unknown 70, Terminated 60, Recruiting 17, Withdrawn 12, Active not recruiting 6, Not yet recruiting 6, Enrolling by invitation 3, Suspended 1
Early Phase 1	26	Completed 18, Unknown 4, Active not recruiting 3, Terminated 1

Follow HIV Infections: new trials by email Literature Review of HIV Infections trials Research Report on HIV Infections

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization smART (Smart Antiretroviral Therapy Assistant), Traditional Prescribing resources - HIV (Human Immunodeficiency Virus), Clinical Decision Support System (CDSS)	Not applicable	Not yet recruiting	Keck School of Medicine of USC	250	2028-09-01	2025-10-22
Social Contact-Based Brief Video Interventions To Reduce Stigma and ImproVe Engagement in HIV Prevention and Care and Mental Health Care for Youth Living With and Vulnerable to HIV Brief Videos for HIV Stigma - HIV, Mental Health	Not applicable	Not yet recruiting	City University of New York, School of Public Health	3900	2028-01-01	2026-10-01
Same-Day Antiretroviral Therapy as a Behavioral Design Intervention to Reduce Stigma in Key Affected Populations SD-ART - Hiv	Not applicable	Not yet recruiting	Yale University	139	2027-10-01	2026-08-31
Scaling Up Implementation Strategies to Improve the DIAGNOSE and PREVENT Pillars for Young MSM in Florida Workforce Development (WD) strategies, Quality Management (QM) and Mystery Shopper (MS) Feedback - Hiv	Not applicable	Not yet recruiting	Florida State University	81	2027-06-01	2026-10-13
Advanced HIV Re-engagement in Care ARC - Advanced HIV Disease	Not applicable	Not yet recruiting	University of Alabama at Birmingham	724	2027-05-01	2026-07-23
Incidence of HPV Infection and HPV-Associated Disease in Screening Indian Men Who Have Sex With HIV-Positive Men Cytology Specimen Collection Procedure, High Resolution Anoscopy with Biopsy, Laboratory Biomarker Analysis - HIV Infection, Human Papillomavirus Infection		Withdrawn	AIDS Malignancy Consortium		2027-04-30	2025-06-06
Incidence of HIV Infection in Screening Indian Men Who Have Sex With Men Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Medical Examination - HIV Infection		Withdrawn	AIDS Malignancy Consortium		2027-04-30	2025-06-06
Integrating Supports to Promote PrEP for Black Adolescents Working With Apps- Atlanta Health MPowerment App - HIV Infections	Not applicable	Not yet recruiting	Emory University	10	2027-04-01	2026-09-22
PrEPwise Pilot Among Black Women in Eastern Virginia PrEPwise, Usual care - HIV Infections, Sexually Transmitted Infection	Not applicable	Not yet recruiting	Boston University	108	2027-04-01	2026-02-11
PositiveLinks for Youth (PL4Y) for Texas PositiveLinks for Youth Smartphone App - Human Immunodeficiency Virus, HIV	Not applicable	Not yet recruiting	The University of Texas Health Science Center at San Antonio	600	2027-04-01	2026-09-04
Safety & Immunogenicity of 426c.Mod.Core-C4b Vaccine With 3M-052-AF+Alum in Infants Perinatally Exposed to HIV But Uninfected 426c.Mod.Core-C4b, 3M-052-AF, Aluminum hydroxide suspension (Alum) - HIV Infections	Phase 1	Not yet recruiting	HIV Vaccine Trials Network	22	2027-03-30	2026-09-18
Medical Mistrust Among Hispanic/Latino Gay, Bisexual and Other Men Who Have Sex With Men (HLMSM) Navigators (peer navigator) training, delayed-intervention - Human Immunodeficiency Virus	Not applicable	Not yet recruiting	Wake Forest University Health Sciences	144	2027-03-01	2026-04-30
Improving TelePrEP Initiation and Retention Outcomes in the US: The MISTR+ Study No Marginal Cost Interventions, Low-Marginal Cost Interventions, Standard of Care - Human Immunodeficiency Virus	Not applicable	Not yet recruiting	Emory University	223165	2027-03-01	2026-09-16
Testing a Multi-Level Approach to Reduce Stigma for Women Living With HIV Labda Siku Moja, Total Facility Approach - HIV (Human Immunodeficiency Virus)	Not applicable	Not yet recruiting	RTI International	680	2027-03-01	2026-10-19
Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda. Kisoboka Amaka, Screening and Referral - HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption	Not applicable	Not yet recruiting	San Diego State University	60	2027-02-01	2026-06-22
Integrated Health Services (IHS): A Structural Intervention to Improve HIV/STI Screening and PrEP Navigation in Primary Care Integrated HIV/STI Testing and PrEP Navigation Model - HIV, STDs	Not applicable	Not yet recruiting	My Brother's Keeper, Inc.	700	2027-02-01	2026-03-03
Combating Related Epidemics in HCV Cepheid GeneXpert HCV Test, Abbott Determine HIV - 1/2 Ag/Ab, Abbott Determine HbsAg 2 - HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV)	Phase 4	Not yet recruiting	Duke University	1280	2027-01-20	2026-10-15
Innate-like and NK Signatures in Chronic-Treated HIV Infection INSTINCT-HIV Blood test - Human Immunodeficiency Virus Infection (HIV)		Not yet recruiting	Hospices Civils de Lyon	100	2027-01-12	2026-09-30
Improving HIV Prevention and Substance Use Post-Sexual Assault Services Enhanced intervention, Usual Care - HIV Infections, Substance Use	Not applicable	Not yet recruiting	The University of Texas Health Science Center, Houston	90	2027-01-04	2025-11-05
Optimizing Implementation of Long Acting Injectable PrEP Plan-Do-Study-Act - HIV Infections	Not applicable	Not yet recruiting	University of Minnesota	20	2027-01-01	2026-06-16

Showing 20 of 6733. Sign in to see all of them.

Narrower conditions

Acquired Immunodeficiency Syndrome (3029)  ·  AIDS-Related Complex (283)  ·  Sexually Transmitted Diseases (201)  ·  Infections (196)  ·  HIV Seropositivity (194)  ·  Hepatitis C (188)  ·  AIDS-Related Opportunistic Infections (167)  ·  Tuberculosis (166)  ·  Substance-Related Disorders (150)  ·  Depression (92)  ·  Hepatitis B (85)  ·  Medication Adherence (85)  ·  Sarcoma, Kaposi (79)  ·  Cardiovascular Diseases (65)

Broader conditions

Blood-Borne Infections (6731)  ·  Genital Diseases (6729)  ·  Urogenital Diseases (6729)  ·  Lentivirus Infections (6722)  ·  Retroviridae Infections (6721)  ·  RNA Virus Infections (6719)  ·  Sexually Transmitted Diseases, Viral (6712)  ·  Immune System Diseases (6711)  ·  Communicable Diseases (6709)  ·  Immunologic Deficiency Syndromes (6706)  ·  Virus Diseases (6702)  ·  Infections (6537)  ·  Sexually Transmitted Diseases (6528)  ·  Slow Virus Diseases (3075)

Interventions

Zidovudine (318)  ·  Ritonavir (306)  ·  Lamivudine (260)  ·  efavirenz (213)  ·  Tenofovir (207)  ·  Raltegravir Potassium (150)  ·  Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (147)  ·  Emtricitabine (146)  ·  Lopinavir (146)  ·  Nevirapine (139)  ·  Didanosine (132)  ·  dolutegravir (125)  ·  Stavudine (124)  ·  abacavir (107)  ·  Darunavir (98)

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID) (1058)  ·  ViiV Healthcare (248)  ·  University of California, San Francisco (130)  ·  University of North Carolina, Chapel Hill (110)  ·  Merck Sharp & Dohme LLC (90)  ·  ANRS, Emerging Infectious Diseases (85)  ·  Bristol-Myers Squibb (82)  ·  University of Washington (82)  ·  Gilead Sciences (80)  ·  Glaxo Wellcome (72)  ·  National Cancer Institute (NCI) (72)  ·  Boehringer Ingelheim (71)  ·  French National Agency for Research on AIDS and Viral Hepatitis (66)  ·  Johns Hopkins University (66)  ·  Columbia University (65)

Countries

United States (3670)  ·  South Africa (426)  ·  France (369)  ·  Puerto Rico (367)  ·  Spain (322)  ·  Canada (306)  ·  United Kingdom (234)  ·  Uganda (226)  ·  Thailand (216)  ·  Italy (200)  ·  Germany (196)  ·  Kenya (181)  ·  Brazil (177)  ·  China (135)  ·  Australia (132)

Top investigators

Pablo Tebas, MD (14)  ·  Kiat Ruxrungtham, MD (13)  ·  Corey L (12)  ·  Belshe R (10)

Results publications

PMID 32779730, PMID 40190112, PMID 25820067, PMID 39324693, PMID 24326304, PMID 33901188, PMID 34817414, PMID 34843602, PMID 34895272, PMID 40655875, PMID 23349878, PMID 24979445, PMID 27572401, PMID 32838558, PMID 39101506, PMID 16220994, PMID 17666313, PMID 18657709, PMID 19571722, PMID 20024643, PMID 22288567, PMID 24086319, PMID 24870935, PMID 25992639, PMID 26743093, PMID 26908541, PMID 28131393, PMID 29767684, PMID 31042791, PMID 31999736, PMID 32829410, PMID 33616229, PMID 34453519, PMID 35508986, PMID 36150048, PMID 37452174, PMID 38160309, PMID 39052748, PMID 40342086, PMID 40354181, PMID 40698814, PMID 40990223, PMID 41845569, PMID 42039169, PMID 42370263, PMID 10218526, PMID 11188837, PMID 11399973, PMID 11964551, PMID 14507605

NIH funding

U01AI068636 (25), U01CA121947 (25), 2008 (21), UM1CA121947 (19), 2009 (18), 2014 (15), 2005 (13), 2015 (12), 2019 (12), U01AI068632 (12), 2004 (10), 2017 (10), 2023 (10), U24CA275417 (9), 2016 (7)