26 completed, 12 not yet recruiting, 10 recruiting, 3 active not recruiting. 27 Not applicable, 14 Phase 4, 7 Phase 2, 7 Phase 3.
Follow Post Operative Analgesia: new trials by email Literature Review of Post Operative Analgesia trials Research Report on Post Operative Analgesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery Lidocaine HCl 0.8% in D5W, Dextrose 5% in water - Pain, Post Operative Analgesia | Phase 4 | Not yet recruiting | Vanderbilt University Medical Center | 2290 | 2026-10-31 | 2026-10-15 |
| A COMPARATIVE STUDY BETWEEN OPIOID-FREE GENERAL ANAESTHESIA AND OPIOID-BASED GENERAL ANAESTHESIA ON THE QUALITY OF RECOVERY IN PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC HYSTRECTOMY: A Randomized Trial Fentanyl-Based Anesthesia, Opioid-Free Anaesthesia (Dexmedetomidine, Ketamine, and Lidocaine) - Post Operative Recovery, Post Operative Nausea and Vomiting (PONV) | Not applicable | Not yet recruiting | Ain Shams University | 66 | 2026-08-22 | 2026-07-31 |
| Postoperative Tizanidine Use in Pelvic Reconstructive Surgery: A Pilot Study Tizanidine, Standard-of-Care Therapy - Post Operative, Post Operative Analgesia | Phase 2 | Recruiting | Hartford Hospital | 186 | 2026-08-21 | 2026-09-21 |
| Photobiomodulation Therapy for Pain Control in Post-Operative Total Knee Arthroplasty Patients: A Pilot Study LightForce XLI - Pain Management, TKA | Not applicable | Not yet recruiting | Mohammad Burney, MD | 15 | 2026-08-01 | 2026-08-06 |
| Comparison Between Paravertebral and Erector Spinal Block Efficacy in Robotic Thoracic Surgeries Paravertebral Nerve Block, ESP block group - Post Operative Analgesia, Regional Anaesthesia | Not applicable | Active not recruiting | Soroka University Medical Center | 60 | 2026-07-01 | 2026-08-24 |
| Analgesic Efficacy of Combined PECS II and PIP Block Versus Thoracic Paravertebral Block Post-Mastectomy Combined PECS II and Superficial PIP Block, Thoracic paravertebral block (TPVB) - Acute Pain, Post Operative Analgesia | Not applicable | Recruiting | Dharmais National Cancer Center Hospital | 72 | 2026-06-29 | 2026-07-31 |
| Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block (REBOUND)_part A Morphine provided via oral PCA, Morphine provided via oral PCA + morphine administered at a scheduled regimen - Post Operative Analgesia, Rebound Pain | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 100 | 2026-06-01 | 2026-06-24 |
| Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block (REBOUND)_part B Morphine provided via oral PCA, Morphine provided via oral PCA + morphine administered at a scheduled regimen - Post Operative Analgesia, Rebound Pain | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 100 | 2026-06-01 | 2026-06-24 |
| Comparative Study Between Ultrasound Guided Paravertebral Plane Block and Erector Spinae Plane Block on Post-operative Analgesia After Total Abdominal Hysterectomy Paravertebral Plane Block, Erector Spinea Plane Block, bupivicaine 0.25% - Post Operative Analgesia | Not applicable | Not yet recruiting | Ain Shams University | 48 | 2026-05-10 | 2026-05-27 |
| Low Versus Standard Volume EXORA Block in Laparoscopic Cholecystectomy EXORA block 15, EXORA block 25 - Pain, Postoperative, Post Operative Analgesia | Not applicable | Recruiting | Fayoum University Hospital | 96 | 2026-04-12 | 2026-09-02 |
| Erector Spinae Plane Versus Quadratus Lumborum Blocks for Pain Management After Total Abdominal Hysterectomy Erector Spinae Plane Block, Quadratus Lumborum Block (QLB) - Post Operative Analgesia | Not applicable | Not yet recruiting | Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad | 60 | 2026-04-01 | 2026-03-18 |
| Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Block With Dexmetomidine vs Dexmethasone Dexmedetomidine, Dexamethasone - Post Operative Analgesia, Dexmedetomidine | Phase 4 | Completed | Pakistan Institute of Medical Sciences | 60 | 2026-03-27 | 2026-07-14 |
| The Effect of Lactoferrin on Pain Management Following Cesarean Section Lactoferrin, Placebo - Cesarean Birth, Post Operative Analgesia | Phase 3 | Not yet recruiting | Ain Shams University | 90 | 2026-03-26 | 2026-03-30 |
| Preoperative High-Dose Oral Paracetamol for Postoperative Analgesia in Children Undergoing Tonsillectomy" Paracetamol (acetaminophen) - Post Operative Analgesia, Tonsillectomy With or Without Adenoidectomy | Not applicable | Not yet recruiting | Thammasat University | 54 | 2026-03-01 | 2026-03-11 |
| Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimally Invasive Left-Sided Colorectal Resection (BAPTAP) Minimally Invasive Left-Sided Colorectal Resection, BAPTAP (Peripheral Autonomic Blockade + TAP Block), Trocar/Incision Infiltration - Colorectal Cancer, Colorectal Surgery | Not applicable | Recruiting | Faculdade de Ciências Médicas de Minas Gerais | 140 | 2026-02-12 | 2026-02-13 |
| Comparison of Efficacy of Bupivacaine Alone vs. Bupivacaine-Tramadol in Lower Limb Surgery Bupivacain only, bupivacain-tramadol - Post Operative Analgesia | Phase 4 | Completed | Farooq Hospital / Akhtar Saeed Medical college Rawalpindi | 60 | 2026-01-01 | 2026-09-18 |
| Supplementary Nerve Blocks Added to the Adductor Canal Block for Postoperative Pain Management in Primary Total Knee Arthroplasty: A Randomized Controlled Comparison of Sciatic, BiFeS, and IPACK Techniques Adductor canal block, BiFeS Block (Biceps Femoris Short Head Block), IPACK block - Post Operative Analgesia, Total Knee Arthroplasty | Not applicable | Recruiting | Erzincan University | 102 | 2025-11-01 | 2026-01-13 |
| Comparison of Pericapsular Nerve Group (PENG) Block With a Combined Femoral, Sciatic, Lateral Femoral Cutaneous Nerve Block for Postoperative Analgesia in Secondary Total Hip Arthroplasty; (REVPET) Pericapsular nerve group (PENG) block with 0.75% ropivacaine guided by ultrasound, Femoral, sciatic and lateral femoral cutaneous nerve block with 0.375% ropivacaine - Hip Arthroplasty Replacement, Post Operative Analgesia | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 50 | 2025-09-30 | 2025-09-22 |
| Transnasal Sphenopalatine Ganglion Block for Postoperative Pain and Recovery in Tonsillectomy (TONwoPA) Transnasal Transmucosal Sphenopalatine Ganglion Block, Lidocaine %5, Saline (0.9% NaCl) - Post Tonsillectomy Pain, Post Operative Analgesia | Not applicable | Completed | Ankara University | 26 | 2025-08-30 | 2026-10-13 |
| Bilateral External Oblique Intercostal Plane Bock (EOIPB) in Upper Abdominal Surgeries Ultrasound guided Rectus sheath block, ultrasound guided external oblique intercostal plane block - Post Operative Analgesia | Not applicable | Completed | Kasr El Aini Hospital | 40 | 2025-07-24 | 2025-12-02 |
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Pain, Postoperative (14) · Agnosia (10) · Bradycardia (3) · Hypotension (3) · Bites and Stings (2) · Vomiting (2) · Acute Pain (1) · Breast Neoplasms (1) · Colorectal Neoplasms (1) · Gallstones (1) · Hypertension (1) · Pain (1)
Pathological Conditions, Signs and Symptoms (24) · Signs and Symptoms (21) · Neurologic Manifestations (20) · Pathologic Processes (17) · Pain (14) · Postoperative Complications (14) · Nervous System Diseases (10) · Neurobehavioral Manifestations (10) · Perceptual Disorders (10) · Cardiovascular Diseases (4) · Vascular Diseases (4) · Arrhythmias, Cardiac (3) · Heart Diseases (3) · Chemically-Induced Disorders (2) · Digestive System Diseases (2)
Dexmedetomidine (5) · Acetaminophen (4) · Bupivacaine (3) · Dexamethasone (3) · Morphine (3) · Ropivacaine (3) · Sodium Chloride (3) · Control Groups (2) · Dental Occlusion (2) · Fentanyl (2) · Lidocaine (2) · Saline Solution (2) · Anesthesia, General (1) · Anesthetics, Local (1) · Glucose (1)
Ain Shams University (4) · Sahiwal medical college sahiwal (4) · Centre Hospitalier Universitaire Vaudois (3) · Assiut University (2) · Cairo University (2) · University Health Network, Toronto (2) · Al-Azhar University (1) · Ankara University (1) · Ashford and St. Peter's Hospitals NHS Trust (1) · Ataturk University (1) · Baylor College of Medicine (1) · Beth Israel Deaconess Medical Center (1) · Catholic University of the Sacred Heart (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Dharmais National Cancer Center Hospital (1)
Egypt (12) · Pakistan (9) · United States (7) · Canada (4) · Turkey (Türkiye) (3) · France (2) · Indonesia (2) · Switzerland (2) · Brazil (1) · China (1) · Israel (1) · Italy (1) · Thailand (1) · Tunisia (1) · United Arab Emirates (1)
Adeel Riaz, MD (4) · Abd-Elazeem A Elbakry, MD (1) · Abeera Zareen, MBBS,FCPS (1) · Amal G Safan, MD (1) · Anahi Perlas, MD, FRCPC (1) · Ben Safa, MD, FRCPC (1) · Danial Shams, MD (1) · Daniel T Abazia, PharmD (1) · Elena Tunitsky, MD (1) · Franck Vandenbroucke-Menu, MD (1) · Jeremy T Wright, MD (1) · Kelani A. Abd El-Salam, Professor (1) · Mohamed A Hamed,, MD (1) · Mohamed A Ollaek, MD (1)
PMID 11130605, PMID 12269398, PMID 16038812, PMID 20223444, PMID 26555871, PMID 27521884, PMID 29423579, PMID 30915987, PMID 31485929, PMID 34626112, PMID 34739706, PMID 35999334, PMID 37635853, PMID 37736711, PMID 38529017, PMID 41078883, PMID 41687037, PMID 41854462, PMID 42711072, PMID 8080219, PMID 8646957
2025 (2)