24 completed. 24 Phase 2, 4 Phase 1, 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 24 | Completed 24 |
| Phase 1 | 4 | Completed 4 |
| Phase 3 | 4 | Completed 4 |
Follow Post-Traumatic Stress Disorder: new trials by email Literature Review of Post-Traumatic Stress Disorder trials Research Report on Post-Traumatic Stress Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Test Whether Taking BI 1358894 for 8 Weeks Helps Adults With Post-traumatic Stress Disorder BI 1358894, Placebo - Post-Traumatic Stress Disorder | Phase 2 | Completed | Boehringer Ingelheim | 318 | 2021-12-07 | 2024-11-07 |
| A Phase 2b Study of BNC210 Tablet Formulation in Adults With Post-Traumatic Stress Disorder (PTSD) BNC210, Placebo - Post-Traumatic Stress Disorder | Phase 2 | Completed | Bionomics Limited | 212 | 2021-07-27 | 2025-02-06 |
| Ketamine and Prolonged Exposure in PTSD ketamine-enhanced prolonged exposure - Post-traumatic Stress Disorder | Phase 1 / Phase 2 | Completed | Minneapolis Veterans Affairs Medical Center | 12 | 2019-04-03 | 2026-10-14 |
| Safety and Efficacy of NYX-783 in Subjects With Post-Traumatic Stress Disorder Placebo oral capsule, NYX-783 - Post-Traumatic Stress Disorder | Phase 2 | Completed | Aptinyx | 160 | 2019-01-25 | 2022-05-17 |
| Phase II Study of BNC210 in PTSD BNC210, Placebo - Post-Traumatic Stress Disorder | Phase 2 | Completed | Bionomics Limited | 193 | 2016-06-30 | 2023-02-27 |
| Effectiveness of PTSD Treatment For Suicidal and Multi-Diagnostic Clients Dialectical Behavior Therapy, Dialectical Behavior Therapy Prolonged Exposure protocol - Post-traumatic Stress Disorder, Suicide | Phase 2 / Phase 3 | Completed | University of Washington | 35 | 2016-02-01 | 2019-09-17 |
| The Role of Computerized Training in Post-Traumatic Stress Disorder Cognitive Bias Modification of Appraisals (CBM-App), Peripheral Vision Task (control condition) - Post-Traumatic Stress Disorder | Phase 1 / Phase 2 | Completed | Ruhr University of Bochum | 80 | 2016-02-01 | 2019-09-17 |
| Trauma Management Therapy for OEF and OIF Combat Veterans 17 week Exposure Therapy Control Arm, Trauma Management Therapy, Intensive 3-Week Trauma Management Therapy - Post-Traumatic Stress Disorder, Combat Disorders | Phase 2 | Completed | University of Central Florida | 180 | 2015-11-01 | 2017-10-31 |
| BraveMind: Advancing the Virtual Iraq/Afghanistan PTSD Exposure Therapy Virtual Reality Exposure Therapy (VRET) - Trauma, Post-Traumatic Stress Disorder | Phase 2 | Completed | Emory University | 15 | 2015-05-01 | 2017-08-09 |
| Bringing What Works to Youth in Corrections: A Trauma Intervention Trauma-Focused Cognitive Behavioral Therapy - Post-Traumatic Stress Disorder | Phase 1 / Phase 2 | Completed | University of Texas at Austin | 57 | 2012-11-01 | 2016-03-17 |
| Treatment of PTSD by Reduction of Traumatic Memory Reconsolidation by Propranolol : a Multisite Trial Propranolol, Trauma reactivation, placebo - Post-traumatic Stress Disorder | Phase 2 | Completed | University Hospital, Toulouse | 87 | 2012-11-01 | 2026-09-25 |
| Randomized Control Trial of Group Intervention With Former War-affected Boys in the Democratic Republic of Congo TF-CBT - Post-traumatic Stress Disorder, Depression | Phase 2 | Completed | Queen's University, Belfast | 58 | 2011-05-01 | 2012-01-18 |
| Treatment of Aggressive Behavior and Post-Traumatic Stress Disorder Narrative Exposure Therapy for violent offenders (NETvo) - Aggressive Behavior, Post-Traumatic Stress Disorder | Phase 2 | Completed | University of Konstanz | 42 | 2011-01-01 | 2012-11-07 |
| Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) With/Without Yohimbine Yohimbine, Placebo - Post-Traumatic Stress Disorder | Phase 2 | Completed | VA Office of Research and Development | 26 | 2010-12-01 | 2018-02-07 |
| Orvepitant (GW823296) in Adult Post Traumatic Stress Disorder orvepitant, Placebo - Post-Traumatic Stress Disorder | Phase 2 | Completed | GlaxoSmithKline | 132 | 2009-11-02 | 2017-09-01 |
| Treatment of Smoking Among Individuals With PTSD Varenicline, Medication Management Counseling, Prolonged Exposure - Cigarette Smoking, Nicotine Dependence | Phase 2 | Completed | University of Pennsylvania | 142 | 2009-01-01 | 2017-11-14 |
| Effectiveness of Cognitive Behavioral Couples Therapy for Post-traumatic Stress Disorder Cognitive behavioral couples therapy for post-traumatic stress disorder (CBCT for PTSD) - Post-traumatic Stress Disorder | Phase 2 / Phase 3 | Completed | Toronto Metropolitan University | 80 | 2008-08-01 | 2013-11-26 |
| Propranolol in Post Traumatic Stress Disorder propranolol - Post-Traumatic Stress Disorder | Phase 2 | Completed | University Hospital, Toulouse | 20 | 2007-04-01 | 2009-01-07 |
| Levetiracetam in Post-Traumatic Stress Disorder levetiracetam, Placebo, Levetriracetam - Post-Traumatic Stress Disorder | Phase 2 / Phase 3 | Completed | Duke University | 16 | 2005-11-01 | 2014-07-21 |
| Virtual Reality (VR) Therapy for Post-Traumatic Stress Disorder (PTSD) Treatment as Usual, Virtual Reality Exposure with Stimulus Control - Post-Traumatic Stress Disorder | Phase 1 / Phase 2 | Completed | Office of Naval Research (ONR) | 136 | 2005-01-01 | 2009-10-09 |
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Stress Disorders, Post-Traumatic (24) · Anxiety Disorders (4) · Wounds and Injuries (3) · Combat Disorders (2) · Depressive Disorder, Major (2) · Aggression (1) · Alcoholism (1) · Cigarette Smoking (1) · Coitus (1) · Conduct Disorder (1) · Depression (1) · Dissociative Disorders (1) · Dysthymic Disorder (1) · Generalized Anxiety Disorder (1) · Military Sexual Trauma (1)
Mental Disorders (24) · Stress Disorders, Traumatic (24) · Trauma and Stressor Related Disorders (24) · Behavior (5) · Behavioral Symptoms (3) · Chemically-Induced Disorders (3) · Depressive Disorder (2) · Mood Disorders (2) · Substance-Related Disorders (2) · Aberrant Motor Behavior in Dementia (1) · Alcohol-Related Disorders (1) · Anxiety Disorders (1) · Attention Deficit and Disruptive Behavior Disorders (1) · Health Behavior (1) · Neurodevelopmental Disorders (1)
Propranolol (2) · Sertraline (2) · Virtual Reality Exposure Therapy (2) · Cognitive Behavioral Therapy (1) · Dialectical Behavior Therapy (1) · Implosive Therapy (1) · Levetiracetam (1) · Risperidone (1) · TRPC inhibitor BI 1358894 (1) · Therapeutics (1) · Varenicline (1) · Yohimbine (1) · orvepitant (1)
Bionomics Limited (2) · Duke University (2) · University Hospital, Toulouse (2) · University of Pennsylvania (2) · Aptinyx (1) · Boehringer Ingelheim (1) · Emory University (1) · GlaxoSmithKline (1) · Minneapolis Veterans Affairs Medical Center (1) · National Center for Complementary and Integrative Health (NCCIH) (1) · National Institute on Alcohol Abuse and Alcoholism (NIAAA) (1) · Office of Naval Research (ONR) (1) · Queen's University, Belfast (1) · Ruhr University of Bochum (1) · Toronto Metropolitan University (1)
United States (19) · France (2) · Germany (2) · Australia (1) · Burundi (1) · Canada (1) · Croatia (1) · Finland (1) · Israel (1) · Mexico (1) · Poland (1) · Sweden (1) · United Kingdom (1)
Jonathan Davidson, M.D. (2) · Anselm Crombach, Dipl.-Psych. (1) · Barbara O Rothbaum, PhD/ABPP (1) · Barbara Rothbaum, Ph.D. (1) · Brenda Wiederhold, PhD (1) · Candice M. Monson, PhD (1) · Cynthia Price, PhD (1) · Deborah C Beidel, Ph.D., ABPP (1) · Edna B Foa, Ph.D. (1) · Edna B. Foa, Ph.D. (1) · Harry Dr Rafferty (1) · Marcella L Woud, PhD (1) · Melanie S Harned, PhD (1) · Molly M Lopez, Ph.D. (1)
PMID 22893167, PMID 23738530, PMID 25809565, PMID 26654474, PMID 29961004, PMID 33176074, PMID 33612830, PMID 35189456, PMID 38872596, PMID 39647171, PMID 40261001
R01DA023507 (1), R01MH062003 (1), R34MH076813 (1), R34MH095210 (1), R34MH106598 (1)