12 completed, 5 recruiting, 5 unknown, 1 not yet recruiting. 7 Phase 4, 5 Not applicable, 2 Phase 1, 2 Phase 2, 1 Early Phase 1.
Follow Platelet Aggregation Inhibitors: new trials by email Literature Review of Platelet Aggregation Inhibitors trials Research Report on Platelet Aggregation Inhibitors
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38) Drug-coated balloon, Single antiplatelet therapy (SAPT), Dual antiplatelet therapy (DAPT) - Coronary Disease, Heart Diseases | Not applicable | Recruiting | Fondazione Ricerca e Innovazione Cardiovascolare ETS | 576 | 2026-01-10 | 2026-01-22 |
| Modulation of Gut MicroFLORA With Rifaximin to Reduce High Platelet Reactivity in Post-ACS Patients on Ticagrelor Rifaximin - ACS - Acute Coronary Syndrome, Ticagrelor | Phase 4 | Not yet recruiting | Collegium Medicum w Bydgoszczy | 50 | 2026-01-01 | 2025-10-02 |
| Personalizing Thromboprophylaxis for Patients With Peripheral Artery Disease Aspirin, Clopidogrel, Ticagrelor - Peripheral Arterial Disease (PAD), Amputation | Not applicable | Recruiting | Massachusetts General Hospital | 484 | 2025-04-29 | 2026-09-11 |
| Algorithm-based Tailoring of Dual Antiplatelet Therapy to Improve Outcomes Following Percutaneous Coronary Interventions Algorithm-guided DAPT duration, Standard-of-care DAPT duration - Percutaneous Coronary Intervention, Platelet Aggregation Inhibitors | Not applicable | Recruiting | Insel Gruppe AG, University Hospital Bern | 2788 | 2023-06-27 | 2025-09-16 |
| Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II Aspirin 81Mg Ec Tab twice daily for 7 days, Aspirin 40Mg Chew Tab twice daily for 7 days, Aspirin 162 mg EC Tab once daily for 7 days - Platelet Aggregation, Type 2 Diabetes | Phase 1 | Recruiting | Montreal Heart Institute | 30 | 2023-06-13 | 2025-12-03 |
| AntiPlatelet theraPy stratEgy followiNg Left Atrial appenDAGe closurE Double antiplatelet therapy, Aspirin, Brain MRI - Atrial Fibrillation, Atrial Appendage | Phase 4 | Recruiting | University Hospital, Bordeaux | 60 | 2022-10-03 | 2026-06-10 |
| Correct Timing of Head Imaging in Trauma Computed tomography - Craniocerebral Trauma, Platelet Aggregation Inhibitors | Unknown | University of Padova | 3200 | 2022-03-01 | 2022-06-01 | |
| Ticagrelor in Elderly Patients Undergoing Percutaneous Coronary Intervention Ticagrelor - Platelet Aggregation Inhibitors, Dual Anti-Platelet Therapy | Completed | The First Affiliated Hospital of Dalian Medical University | 1505 | 2021-07-20 | 2021-08-10 | |
| Pharmacodynamics and Pharmacokinetics of Aspirin Inhalation Powder With Non-Enteric-Coated Chewable Aspirin Aspirin - Platelet Aggregation Inhibitors | Phase 1 | Completed | Inova Health Care Services | 19 | 2019-07-16 | 2020-04-01 |
| Maintenance Of aNtiplatElet Therapy in Patients With Coronary Stenting Undergoing Surgery (MONET BRIDGE) Cangrelor - Platelet Aggregation Inhibitors | Phase 2 | Unknown | Ospedale Santa Croce-Carle Cuneo | 140 | 2019-06-01 | 2019-03-05 |
| The Efficacy, Safety and Pharmacokinetic of Antiplatelet Therapy for Vicagrel Vicagrel 5mg, Vicagrel 6mg, Vicagrel 7.5mg - Coronary Artery Disease, Percutaneous Coronary Intervention | Phase 2 | Completed | Jiangsu vcare pharmaceutical technology co., LTD | 279 | 2018-08-30 | 2019-09-23 |
| ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-2 Study for the Patients With ACS 1-months DAPT, 12-month DAPT - Acute Coronary Syndrome, Acute Myocardial Infarction | Phase 4 | Unknown | Kyoto University, Graduate School of Medicine | 3008 | 2018-04-02 | 2024-06-14 |
| Management and Outcomes of Anti-thrombotic Medication Use in Thrombocytopenia Hold, Prophylactic dose antithrombotic, Change antithrombotic Drug - Hematologic Neoplasms, Thrombocytopenia | Unknown | Maastricht University Medical Center | 300 | 2018-03-20 | 2020-09-17 | |
| The Compliance of DAPT and Statins on Clinical Outcomes in Percutaneous Coronary Intervention Patients DAPT, Statin - Platelet Aggregation Inhibitors, Hydroxymethylglutaryl-coa Reductase Inhibitors | Completed | Samsung Medical Center | 47291 | 2017-04-06 | 2018-12-24 | |
| Predischarge Bundle to Minimize Negative Impact on Quality of Life of Nuisance Bleedings good clinical practice, bundle group - Myocardial Ischemia, Hemorrhage | Not applicable | Completed | University Hospital of Ferrara | 448 | 2015-09-01 | 2018-05-02 |
| GM03 - Platelet RNA Signatures of Aspirin Aspirin, Ticagrelor - Platelet Aggregation Inhibitors, Aspirin | Early Phase 1 | Completed | Duke University | 135 | 2013-11-01 | 2022-03-14 |
| Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial Infarction Prasugrel, Ticagrelor - Myocardial Infarction, Angioplasty, Balloon, Coronary | Phase 4 | Completed | Faculty Hospital Kralovske Vinohrady | 1226 | 2013-01-01 | 2017-08-11 |
| ACCEL-LOADING-ACS Study Dual Anti-Platelet Therapy (DAPT), Triple Anti-Platelet Therapy (TAPT) - Platelet Aggregation Inhibitors, Anti-inflammatory Agent | Phase 4 | Completed | Gyeongsang National University Hospital | 220 | 2010-07-01 | 2013-09-24 |
| Plavix, Prasugrel and Drug Eluting Stents Pilot Trial Loading Dose Arm, Maintenance Dose Arm - Coronary Artery Disease, Platelet Aggregation Inhibitors | Not applicable | Unknown | St. Francis Hospital, New York | 1000 | 2010-04-01 | 2010-04-15 |
| The Influence of CYP2C19 Polymorphism and Clinical Outcomes in Stroke Patients Clopidogrel - Platelet Aggregation Inhibitors | Completed | National Cerebral and Cardiovascular Center, Japan | 518 | 2009-10-01 | 2016-03-18 |
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Coronary Artery Disease (5) · Acute Coronary Syndrome (3) · Atrial Fibrillation (2) · Coronary Disease (2) · Myocardial Infarction (2) · Myocardial Ischemia (2) · Arterial Occlusive Diseases (1) · Atherosclerosis (1) · Cardiovascular Diseases (1) · Coronary Stenosis (1) · Craniocerebral Trauma (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Dysbiosis (1) · Heart Diseases (1)
Cardiovascular Diseases (12) · Heart Diseases (11) · Vascular Diseases (11) · Myocardial Ischemia (8) · Arteriosclerosis (6) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Arterial Occlusive Diseases (5) · Coronary Disease (4) · Arrhythmias, Cardiac (2) · Infarction (2) · Ischemia (2) · Necrosis (2) · Nervous System Diseases (2) · Atherosclerosis (1)
Clopidogrel (7) · Aspirin (6) · Ticagrelor (4) · 2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine (2) · Prasugrel Hydrochloride (2) · Dual Anti-Platelet Therapy (1) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (1) · Mastication (1) · Percutaneous Coronary Intervention (1) · Rifaximin (1) · Rivaroxaban (1) · Standard of Care (1) · Thrombelastography (1) · Tomography, X-Ray Computed (1) · cangrelor (1)
Collegium Medicum w Bydgoszczy (1) · Duke University (1) · Faculty Hospital Kralovske Vinohrady (1) · Fondazione Ricerca e Innovazione Cardiovascolare ETS (1) · Gyeongsang National University Hospital (1) · Inova Health Care Services (1) · Insel Gruppe AG, University Hospital Bern (1) · Jiangsu vcare pharmaceutical technology co., LTD (1) · Kyoto University, Graduate School of Medicine (1) · Maastricht University Medical Center (1) · Massachusetts General Hospital (1) · Montreal Heart Institute (1) · National Cerebral and Cardiovascular Center, Japan (1) · Ospedale Santa Croce-Carle Cuneo (1) · R&D Cardiologie (1)
United States (6) · Italy (5) · China (2) · Japan (2) · Netherlands (2) · South Korea (2) · Belgium (1) · Bosnia and Herzegovina (1) · Canada (1) · Czechia (1) · France (1) · Israel (1) · Poland (1) · Switzerland (1)
Alan R. Shuldiner, MD (1) · Anna Falanga, MD (1) · Avi Leader, MD (1) · Deepak Voora, MD (1) · Guillaume Marquis Gravel, MD, MSc (1) · Jacek Kubica, Prof. (1) · Jae-Hyeong Park, MD, PhD (1) · Jin-Ho Choi, MD, PhD (1) · Jon Suh, MD, PhD (1) · Keun-Ho Park, MD (1) · Kyounghoon Lee, MD, PhD (1) · Miklos Rohla, MD, PhD (1)
PMID 17394957, PMID 19706858, PMID 19853687, PMID 20118150, PMID 21881565, PMID 23111421, PMID 23392654, PMID 23415013, PMID 23809542, PMID 24970794, PMID 26374108, PMID 27799230, PMID 28832589, PMID 29154813, PMID 29415203, PMID 29653637, PMID 33170486, PMID 35234821, PMID 35400997, PMID 35912647, PMID 36599584, PMID 36873770, PMID 41847750
U01GM074518 (1)