11 completed, 4 recruiting, 3 unknown, 2 not yet recruiting. 10 Phase 4, 5 Not applicable, 4 Phase 3, 1 Phase 2.
Follow Dual Anti-Platelet Therapy: new trials by email Literature Review of Dual Anti-Platelet Therapy trials Research Report on Dual Anti-Platelet Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study on Anti-Thrombotic Regimens for Secondary Prevention in Ischemic Stroke Patients With Possible Benefit From Anticoagulation Therapy Rivaroxaban, or Edoxaban , or Apixaban , or Dabigatran, Aspirin - Stroke, Acute Ischemic Stroke | Phase 3 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 680 | 2026-08-15 | 2026-08-05 |
| Efficacy, Safety, and ToLerability of Switching to A Two-Drug Regimen With DTG/3TC Compared to Maintaining A Three-Drug REgimen With BIC/FTC/TAF or DTG/3TC/ABC in ViroLogically SupprEssed PeopLe Living With HIV After 24 and 48 Weeks of Follow-Up Standard Medical Therapy, dual therapy - HIV Infections | Phase 4 | Recruiting | José Antonio Mata Marín | 156 | 2025-07-12 | 2025-08-22 |
| Safety, Tolerability and Effectiveness of DTG/3TC vs BIC/TAF/FTC in PWH Without Antiretroviral Experience DTG/3TC, Bictegravir (BIC) plus Emtricitabine (FTC) plus Tenofovir Alafenamide (TAF) - HIV Infection, Metabolic Syndrome | Phase 4 | Recruiting | Instituto Mexicano del Seguro Social | 124 | 2025-04-01 | 2025-06-26 |
| Anti-Platelets in Chronic Obstructive Pulmonary Disease dual anti-platelet therapy, Placebo - COPD, Emphysema | Phase 2 | Completed | Brigham and Women's Hospital | 15 | 2024-03-27 | 2026-05-14 |
| Effectiveness and Safety of Darunavir/Cobicistat Plus Lamivudine Versus Darunavir/Cobicistat Plus Tenofovir/Emtricitabine in Virologically Suppressed HIV-1-positive Individuals in Mexico dual therapy, Standard Medical Therapy - HIV Infection | Phase 4 | Recruiting | José Antonio Mata Marín | 138 | 2023-11-09 | 2025-04-04 |
| Efficacy and Safety of Triple Therapy in Patients With Anti-MDA5 Antibody-positive Dermatomyositis triple therapy, dual-therapy - Dermatomyositis, Adult Type, Interstitial Lung Disease | Phase 4 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 120 | 2022-01-01 | 2022-05-26 |
| Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVas™ BRS System Single anti-platelet therapy, Dual anti-platelet therapy - Coronary Heart Disease | Not applicable | Not yet recruiting | Lepu Medical Technology (Beijing) Co., Ltd. | 2150 | 2021-09-01 | 2021-08-06 |
| Appropriate Duration of Anti-Platelet straTegy in Patients With Advance Chronic Kidney Disease After New Generation Drug Eluting Stents (ADAPT-CKD) dual anti-platelet therapy at least 6 months, dual anti-platelet therapy 3months or less - Chronic Kidney Diseases | Not applicable | Recruiting | Yonsei University | 900 | 2021-03-23 | 2026-01-21 |
| A Phase IV Study to Assess the Impact of the Change of Antiretroviral Treatment From Dual Therapy to Triple Therapy on Inflammation in Patients With HIV Infection Dual Therapy, Triple therapy - HIV Infections | Phase 4 | Completed | Fundacion SEIMC-GESIDA | 141 | 2019-10-10 | 2024-10-01 |
| Dolutegravir-Lamivudine as Dual Therapy in naïve HIV-Infected Patients With Documented M184V Mutation:A Pilot Study Dolutegravir plus lamivudine - HIV-1 Infection | Phase 4 | Withdrawn | Pedro Cahn | 2019-05-22 | 2022-04-12 | |
| Duration of Dual Anti-Platelet Therapy (DUAL-ACS) 3 months dual anti-platelet therapy, 12 months dual anti-platelet therapy - Acute Coronary Syndrome, Coronary Artery Disease | Phase 4 | Completed | University of Edinburgh | 5094 | 2018-12-11 | 2026-02-18 |
| Dual Obstructive Sleep Apnea Therapy Dual Therapy - Obstructive Sleep Apnea | Not applicable | Unknown | University of British Columbia | 30 | 2018-03-08 | 2018-05-02 |
| Metoclopramide-Ondansetron vs. Metoclopramide Therapy for Treatment of Nausea and Vomiting Post Laparoscopic Surgery Dual therapy, Monotherapy, General anesthesia - Postoperative Nausea and Vomiting | Not applicable | Completed | Makassed General Hospital | 120 | 2018-02-15 | 2019-09-27 |
| APixaban vs. PhenpRocoumon in Patients With ACS and AF: APPROACH-ACS-AF Dual Therapy, Triple Therapy - Acute Coronary Syndrome, Atrial Fibrillation | Phase 4 | Completed | LMU Klinikum | 403 | 2016-06-01 | 2020-08-14 |
| Trial to Evaluate the Interest of a Reductive Anti Retroviral Strategy Using Dual Therapy Inspite of Triple Therapy triple therapy, dual therapy - HIV | Phase 3 | Completed | University Hospital, Tours | 224 | 2014-12-01 | 2025-12-26 |
| Real Life Long-term Adherence to Ticagrelor After PCI for Acute Coronary Syndromes Ticagrelor - Acute Coronary Syndrome (ACS) | Completed | IHF GmbH - Institut für Herzinfarktforschung | 700 | 2014-08-01 | 2018-06-14 | |
| Leaders Free Japan Percutaneous coronary intervention (PCI), Dual Anti Platelet Therapy - Coronary Disease | Phase 3 | Unknown | Biosensors Europe SA | 139 | 2014-07-01 | 2015-09-29 |
| COBRA SHIELD OCT Study Aspirin, Resolute Integrity DES, COBRA PzF - Stable Angina | Not applicable | Terminated | CeloNova BioSciences, Inc. | 8 | 2014-06-01 | 2020-10-06 |
| Optimal Duration of Clopidogrel in Second-Generation Drug-Eluting Stents 6-month dual anti-platelet therapy, 12-month dual anti-platelet therapy, Zotarolimus eluting stent - Ischemic Heart Disease | Phase 4 | Completed | Gangnam Severance Hospital | 1368 | 2011-05-02 | 2017-02-17 |
| Duration of Dual Antiretroviral Therapy in Virologically Suppressed People Living With HIV and Factors Associated With Switching to Tritherapy : a Real-life Cohort dual therapy - HIV Infections | Completed | Tourcoing Hospital | 580 | 2011-01-01 | 2023-11-01 |
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HIV Infections (5) · Acute Coronary Syndrome (3) · Coronary Artery Disease (2) · Coronary Disease (2) · Angina, Stable (1) · Atrial Fibrillation (1) · Dermatomyositis (1) · Emphysema (1) · Inflammation (1) · Intermittent Claudication (1) · Ischemic Stroke (1) · Lung Diseases, Interstitial (1) · Metabolic Syndrome (1) · Myocardial Ischemia (1) · Myocardial Reperfusion Injury (1)
José Antonio Mata Marín (2) · Biosensors Europe SA (1) · Boston Scientific Corporation (1) · Brigham and Women's Hospital (1) · CeloNova BioSciences, Inc. (1) · Fundacion SEIMC-GESIDA (1) · Gangnam Severance Hospital (1) · Gyeongsang National University Hospital (1) · IHF GmbH - Institut für Herzinfarktforschung (1) · Instituto Mexicano del Seguro Social (1) · LMU Klinikum (1) · Lepu Medical Technology (Beijing) Co., Ltd. (1) · Makassed General Hospital (1) · Pedro Cahn (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1)
Mexico (3) · China (2) · France (2) · Germany (2) · South Korea (2) · United States (2) · Argentina (1) · Canada (1) · Finland (1) · Japan (1) · Lebanon (1) · Spain (1) · United Kingdom (1)
Carrie L Pistenmaa, MD, MS (1) · Daniel G Clair, MD (1) · David Newby (1) · Jae-Hyeong Park, MD, PhD (1) · Jon Suh, MD, PhD (1) · Jung-Sun Kim, MD, PhD, FESC (1) · Keun-Ho Park, MD (1)
PMID 17394957, PMID 20118150, PMID 24754280, PMID 29878086, PMID 31350995, PMID 32588238, PMID 39055703, PMID 41932491
K23HL141651 (1)