104 completed, 42 unknown, 19 recruiting, 18 terminated. 105 Not applicable, 38 Phase 2, 24 Phase 3, 11 Phase 1, 8 Phase 4.
Follow Peripheral Neuropathy: new trials by email Literature Review of Peripheral Neuropathy trials Research Report on Peripheral Neuropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Shortwave Diathermy In-home Treatment for Indianapolis VA-only Patients Diagnosed With Peripheral Artery Disease and Peripheral Neuropathy Replexa shortwave diathermy - Peripheral Arterial Disease, Peripheral Neuropathy | Not applicable | Withdrawn | Indiana University | 2026-09-24 | 2026-10-29 | |
| A Mixed-Methods Exploratory Pilot Study of the Investigational MYNERVA Leia Sensory Prosthesis in U.S. Adults With Peripheral Neuropathy Leia Sensory Prosthesis - Peripheral Neuropathy | Not applicable | Not yet recruiting | Mynerva Inc. | 100 | 2026-09-18 | 2026-09-24 |
| Acupuncture and Exercise for EV-Pembro-Induced Peripheral Neuropathy Acupuncture, Exercise - Metastatic Bladder Cancer, Peripheral Neuropathy | Not applicable | Recruiting | Dana-Farber Cancer Institute | 20 | 2026-09-03 | 2026-10-26 |
| Desloratadine to Prevent Taxane-induced Peripheral Neuropathy in Patients With Breast Cancer Desloratodine, Placebo - Breast Cancer, Peripheral Neuropathy | Phase 2 | Recruiting | Montefiore Medical Center | 116 | 2026-09-01 | 2026-08-26 |
| Sacituzumab Tirumotecan vs MMAE-ADCs in Advanced Urothelial Carcinoma (FUSCC-SPARE-UC-01) Sacituzumab Tirumotecan, MMAE-based ADC, Sacituzumab Tirumotecan (Observational Cohort) - Bladder Cancer, Metastatic Urothelial Carcinoma | Phase 2 | Not yet recruiting | Fudan University | 75 | 2026-07-15 | 2026-06-23 |
| Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain Chronic Pain, PERIPHERAL NEUROPATHY | Recruiting | Yale University | 80 | 2026-06-20 | 2026-08-21 | |
| Randomized, Sham-Controlled Investigation of the Leia Sensory Prosthesis in Individuals With Peripheral Neuropathy Active wearable device, Sham wearable device - Peripheral Neuropathy | Not applicable | Recruiting | MYNERVA AG | 80 | 2026-06-03 | 2026-07-15 |
| Effect of Hands and Feet Exercises on Taxane Based Chemotherapy Induced Peripheral Neuropathy in Patients With Solid Tumors Structured Hand and Foot Exercises - Peripheral Neuropathy | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 58 | 2026-06-01 | 2026-05-06 |
| Electroacupuncture for Preventing Chemotherapy-Induced Peripheral Neuropathy in Patients With Advanced Cancer True electroacupuncture, True thumbtack needle, Sham electroacupuncture - Electroacupuncture, Chemotherapy | Not applicable | Not yet recruiting | Affiliated Hospital of Qinghai University | 264 | 2026-05-25 | 2026-06-12 |
| Electroacupuncture for Preventing Chemotherapy-Induced Peripheral Neuropathy in Patients With Early-stage Cancer True electroacupuncture, True thumbtack needle, Sham electroacupuncture - Electroacupuncture, Chemotherapy | Not applicable | Not yet recruiting | Affiliated Hospital of Qinghai University | 278 | 2026-05-25 | 2026-06-23 |
| WIREDUP: Wearable Insoles for Recurrent Diabetic Ulcer Prevention Orpyx Sensory Insole System - Diabetes, Peripheral Neuropathy | Not applicable | Recruiting | Johns Hopkins University | 400 | 2026-04-22 | 2026-07-14 |
| The Effect of Oral DLBS1033 in Patients With Diabetic Polyneuropathy DLBS1033, Placebo Comparator: Placebo + Standard Therapy - Diabetic Polyneuropathy, Peripheral Nervous System Diseases | Phase 2 / Phase 3 | Not yet recruiting | Universitas Sebelas Maret | 34 | 2026-03-01 | 2026-03-16 |
| Nerve Excitability in Cisplatin-Induced Peripheral Neuropathy Threshold Tracking Nerve Conduction Studies - Peripheral Neuropathy Due to Chemotherapy, Peripheral Neuropathy | Not applicable | Recruiting | Ka-Wai Ho | 60 | 2026-01-31 | 2026-04-22 |
| Optimizing Integrative Oncology Approaches to Address Chemotherapy-induced Peripheral Neuropathy in Gastrointestinal (GI) Cancer Patients: A SMART Pilot Study Tai Chi/Qi Gong, α- Lipoic acid, Acupuncture - Peripheral Neuropathy | Not applicable | Recruiting | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 60 | 2026-01-20 | 2026-04-14 |
| Exploring the Effects of Hand and Foot Exercise Intervention in Older Adults With Gynecological Cancer Receiving Chemotherapy Improvement of Peripheral Neuropathy and Quality of Life hand and foot exercises - Peripheral Neuropathy, Cervical Cancer | Not applicable | Not yet recruiting | Taipei Veterans General Hospital, Taiwan | 74 | 2026-01-01 | 2026-01-23 |
| The Pressure Relieving Capacity of Siliconepads Compared to Felted Foam to Relieve Caput Metatarsal 2 in a Population With Diabetes Siliconepad, Felted foam - Diabete Mellitus, Peripheral Neuropathy | Not yet recruiting | University Hospital, Ghent | 80 | 2025-10-08 | 2025-09-22 | |
| Generative AI Impact on Rheumatoid Arthritis Complications Diagnosis Generative AI prediction report for RA complications - Rheumatoid Arthritis (RA, Osteoporosis | Completed | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | 57 | 2025-10-01 | 2026-10-26 | |
| Multimodal Ultrasound in Peripheral Neuropathy Peripheral Neuropathy | Not yet recruiting | Assiut University | 50 | 2025-10-01 | 2025-02-10 | |
| Daratumumab for Polyneuropathy Associated With MGUS Daratumumab and hyaluronidase-fihj - Peripheral Neuropathy, Monoclonal Gammopathy of Undetermined Significance | Phase 2 | Withdrawn | Georgetown University | 2025-09-26 | 2025-10-01 | |
| Fenofibrate Role in the Prophylaxis From Peripheral Neuropathy Induced by Bortezomib, Lenalidomide and Dexamethasone (VRd) Protocol in the Treatment of Patients With Multiple Myeloma (MM) Bortezomib + Lenalidomide + Dexamethasone + Fenofibrate 160 mg tablet, Bortezomib + Lenalidomide + Dexamethasone - Peripheral Neuropathy, Multiple Myeloma, Neoplasms | Phase 4 | Recruiting | Tanta University | 44 | 2025-08-30 | 2025-11-04 |
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Peripheral Nervous System Diseases (214) · Pain (34) · Diabetes Mellitus (28) · Breast Neoplasms (24) · Neuralgia (15) · Chronic Pain (12) · Diabetic Neuropathies (12) · Neurotoxicity Syndromes (10) · Multiple Myeloma (7) · Diabetic Foot (6) · Neoplasms (6) · Agnosia (5) · Complex Regional Pain Syndromes (5) · Lymphoma (5) · Marijuana Abuse (5)
Nervous System Diseases (213) · Neuromuscular Diseases (213) · Pathological Conditions, Signs and Symptoms (76) · Signs and Symptoms (65) · Neurologic Manifestations (63) · Endocrine System Diseases (44) · Neoplasms (44) · Nutritional and Metabolic Diseases (38) · Metabolic Diseases (36) · Neoplasms by Site (36) · Skin and Connective Tissue Diseases (34) · Glucose Metabolism Disorders (33) · Skin Diseases (32) · Immune System Diseases (29) · Pain (25)
Acupuncture Therapy (10) · Lidocaine (6) · Exercise (5) · Glutamine (5) · nabiximols (5) · Duloxetine Hydrochloride (4) · Surveys and Questionnaires (4) · Nerve Conduction Studies (3) · Pregabalin (3) · Saline Solution (3) · Sodium Chloride (3) · Thioctic Acid (3) · Transcutaneous Electric Nerve Stimulation (3) · Biopsy (2) · Cryotherapy (2)
Mayo Clinic (6) · M.D. Anderson Cancer Center (5) · Apurano Pharmaceuticals GmbH (4) · Assiut University (4) · Jazz Pharmaceuticals (4) · Johns Hopkins University (4) · Washington University School of Medicine (4) · Cairo University (3) · Indiana University (3) · Mansoura University (3) · Memorial Sloan Kettering Cancer Center (3) · NYU Langone Health (3) · National Taiwan University Hospital (3) · Virginia Commonwealth University (3) · Academic and Community Cancer Research United (2)
United States (105) · Egypt (15) · China (8) · Turkey (Türkiye) (8) · Germany (7) · United Kingdom (7) · France (5) · Taiwan (5) · Italy (4) · South Korea (4) · Canada (3) · Pakistan (3) · Belgium (2) · Brazil (2) · Denmark (2)
Charles Loprinzi (5) · Barbara Hoggart, MBBS, FRCA (2) · Rodica Pop-Busui, MD, PhD (2) · Ting Bao, MD, DABMA, MS (2) · A. Gordon Smith, MD (1) · Albert Y Leung, M.D. (1) · Alvaro Pereira (1) · Amr S Saad, Assoc. Prof (1) · Amr Shafik, Assoc. Prof (1) · Amy Darragh, PhD, OTR/L (1) · Angela Hansen (1) · Ann Marie Nayback-Beebe, PhD, FNP-BC (1)
PMID 31456070, PMID 14745057, PMID 16235318, PMID 17997224, PMID 22547012, PMID 23538593, PMID 23549581, PMID 23565581, PMID 24420962, PMID 24494204, PMID 24531792, PMID 24886772, PMID 26203063, PMID 26248652, PMID 26603828, PMID 26744637, PMID 28257145, PMID 28614678, PMID 29189275, PMID 29381569, PMID 29421164, PMID 32102167, PMID 33249081, PMID 33522900, PMID 34059410, PMID 34213086, PMID 34312211, PMID 34889293, PMID 36527520, PMID 37583905, PMID 37774185, PMID 37899433, PMID 38107641, PMID 38308227, PMID 38897103, PMID 39447017, PMID 39593566, PMID 39727210, PMID 40918409, PMID 41352124, PMID 42751727, PMID 8857633, PMID 9415498
P30CA015083 (2), 2025 (1), F32DK065400 (1), M01RR000036 (1), P30CA006927 (1), P30CA012197 (1), R01HD036802 (1), R21CA256136 (1), R21HD048972 (1), R44AG040865 (1), U10CA037420 (1), U10CA081920 (1)