6 completed, 3 recruiting, 3 withdrawn, 1 active not recruiting. 15 Phase 2, 4 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 15 | Completed 6, Recruiting 3, Withdrawn 3, Active not recruiting 1, Terminated 1, Unknown 1 |
| Phase 1 | 4 | Withdrawn 2, Completed 1, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Peripheral Nerve Injuries: new trials by email Literature Review of Peripheral Nerve Injuries trials Research Report on Peripheral Nerve Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) VMD-3866 Gel, Placebo Gel - Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain | Phase 2 | Recruiting | VM Therapeutics LLC | 16 | 2025-12-12 | 2026-10-21 |
| 4-AP Peripheral Nerve Crossover Trial 4-Aminopyridine, Placebo - Peripheral Nerve Injury, Crush Injury | Phase 2 | Recruiting | University of Arizona | 68 | 2025-04-21 | 2025-08-05 |
| A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury IncobotulinumtoxinA, Placebo - Moderate to Severe Chronic Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) or Peripheral Nerve Injury | Phase 2 | Completed | Merz Therapeutics GmbH | 123 | 2023-11-22 | 2026-05-05 |
| Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion) NTX-001 - Peripheral Nerve Injuries | Phase 2 | Active not recruiting | Major Extremity Trauma Research Consortium | 40 | 2023-06-01 | 2026-09-10 |
| Safety and Efficacy of NTX-001 Compared to SOC in Acute Single Peripheral Nerve Injuries NTX-001 - Peripheral Nerve Injuries | Phase 2 | Completed | Neuraptive Therapeutics Inc. | 51 | 2020-09-25 | 2026-10-15 |
| Polyethylene Glycol to Improve Sensation Following Digital Nerve Laceration Polyethylene Glycol 3350, Normal Saline - Peripheral Nerve Injury, Nerve Injury | Phase 1 / Phase 2 | Withdrawn | Nova Scotia Health Authority | 2020-06-26 | 2024-01-05 | |
| Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury Tesamorelin 2 Milligrams (MG) - Peripheral Nerve Injuries | Phase 2 | Recruiting | Johns Hopkins University | 36 | 2018-06-01 | 2025-11-12 |
| The Effect of Pre-operative Electrical Stimulation on Peripheral Nerve Regeneration. Electrical Stimulation, Sham Stimulation - Peripheral Nerve Injuries, Sensory Deficit | Phase 2 / Phase 3 | Completed | University of Alberta | 38 | 2017-10-01 | 2024-09-19 |
| Safety and Efficacy Study of Neovasculgen (Pl-VEGF165) Gene Therapy in Patients With Peripheral Nerve Injury Neovasculgen - Peripheral Nerve Injury | Phase 1 / Phase 2 | Unknown | Artgen Biotech | 45 | 2015-04-01 | 2015-02-02 |
| Effect of Rufinamide on Chronic Postthoracotomy Pain Syndrome Rufinamide - Peripheral Nerve Injuries, Pain | Phase 2 | Withdrawn | University of Zurich | 2014-03-01 | 2015-07-21 | |
| Efficacy of Etoricoxib on Peripheral Hyperalgesia Etoricoxib, placebo - Causalgia, Polyneuropathy | Phase 2 | Terminated | Ruhr University of Bochum | 9 | 2011-02-01 | 2012-08-24 |
| Enhancement of Functional Recovery After Peripheral Nerve Injury With Tacrolimus Tacrolimus - Peripheral Nerve Injury | Phase 1 / Phase 2 | Withdrawn | Washington University School of Medicine | 2010-08-01 | 2018-02-13 | |
| Study in Neuropathic Pain Patients With Peripheral Nerve Injury GW856553, PLACEBO - Pain, Neuropathic | Phase 2 | Completed | GlaxoSmithKline | 168 | 2009-08-01 | 2017-02-17 |
| Study of Capsaicin Patch for the Management of Peripheral Neuropathic Pain CAPNP, 50 ug/cm2 capsaicin patch, CAPNP, 100 ug/cm2 capsaicin patch, 0.075% capsaicin cream - Peripheral Nerve Injury, Postherpetic Neuralgia | Phase 1 / Phase 2 | Completed | Samyang Biopharmaceuticals Corporation | 60 | 2009-02-01 | 2017-05-01 |
| Comparing Primary With Secondary Repair of Based on Electrodiagnostic Assessment and Clinical Examination primary repair, secondary repair - Peripheral Nerve Injury | Phase 2 | Completed | Isfahan University of Medical Sciences | 46 | 2008-03-01 | 2010-05-20 |
Neuralgia, Postherpetic (3) · Neuralgia (2) · Pain (2) · Agnosia (1) · Cancer Pain (1) · Causalgia (1) · Chronic Pain (1) · Crush Injuries (1) · Disease (1) · Hypesthesia (1) · Paresthesia (1) · Polyneuropathies (1) · Radiculopathy (1) · Trauma, Nervous System (1)
Nervous System Diseases (15) · Neuromuscular Diseases (15) · Peripheral Nervous System Diseases (15) · Wounds and Injuries (15) · Trauma, Nervous System (14) · Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Pain (4) · Neuralgia (3) · Autonomic Nervous System Diseases (1) · Complex Regional Pain Syndromes (1) · Neurobehavioral Manifestations (1) · Pathologic Processes (1) · Perceptual Disorders (1)
4-Aminopyridine (1) · 6-(5-((cyclopropylamino)carbonyl)-3-fluoro-2-methylphenyl)-N-(2,2-dimethylprpyl)-3-pyridinecarboxamide (1) · Botulinum Toxins, Type A (1) · Electric Stimulation (1) · Etoricoxib (1) · Saline Solution (1) · Tacrolimus (1) · incobotulinumtoxinA (1) · polyethylene glycol 3350 (1) · rufinamide (1) · tesamorelin (1)
Artgen Biotech (1) · GlaxoSmithKline (1) · Isfahan University of Medical Sciences (1) · Johns Hopkins University (1) · Major Extremity Trauma Research Consortium (1) · Merz Therapeutics GmbH (1) · Neuraptive Therapeutics Inc. (1) · Nova Scotia Health Authority (1) · Ruhr University of Bochum (1) · Samyang Biopharmaceuticals Corporation (1) · University of Alberta (1) · University of Arizona (1) · University of Zurich (1) · VM Therapeutics LLC (1) · Washington University School of Medicine (1)
United States (4) · Germany (2) · Spain (2) · United Kingdom (2) · Australia (1) · Bulgaria (1) · Canada (1) · Denmark (1) · France (1) · Hungary (1) · Iran (1) · Norway (1) · Poland (1) · Russia (1) · South Korea (1)
Ala Elhelali, PhD (1) · Christoph Maier, Dr.med (1) · John Elfar, MD (1) · Julie Beveridge, MD (1) · K Ming Chan, MB ChB (1) · Konrad Maurer, MD (1) · Sami Tuffaha, MD (1) · Seth Schulman, MD (1) · Thomas H Tung, MD (1)
2009 (1), R01NS111293 (1)