22 completed, 10 unknown, 9 recruiting, 4 active not recruiting. 18 Not applicable, 7 Phase 4, 2 Early Phase 1, 2 Phase 1, 2 Phase 2.
Follow Parkinsonism: new trials by email Literature Review of Parkinsonism trials Research Report on Parkinsonism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and Parkinsonism Multimodal visuospatial and topographical memory assessment - Parkinson's Disease, Parkinsonism | Not yet recruiting | IRCCS San Raffaele Roma | 80 | 2026-09-01 | 2026-09-18 | |
| Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD Acute intermittent hypercapnic hypoxia (AIHH), Acute intermittent hypercapnic normoxia (AIHN) - Parkinson Disease, Parkinsonism | Not applicable | Recruiting | University of Florida | 32 | 2026-08-12 | 2026-08-21 |
| The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients Conventional Exercise, Functional Turning Exercises - Parkinson Disease, Parkinsonism | Not applicable | Completed | Uskudar University | 50 | 2026-03-01 | 2026-10-07 |
| Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG) Observational Data Collection - Freezing of Gait, Parkinson's Disease | Recruiting | Tianjin Huanhu Hospital | 700 | 2026-02-28 | 2026-03-10 | |
| The Effect of Spinal Cord Stimulation on Orthostatic Hypotension in Parkinsonism and Its Related Mechanisms Epidural spinal cord stimulation, Transcutaneous spinal cord stimulation - Parkinsonism | Not applicable | Not yet recruiting | Ruijin Hospital | 40 | 2026-01-01 | 2026-01-09 |
| Observational Case Series of Patients With Parkinson's Disease (PD) Attending a Complementary Medicine Neuro-degenerative Disease (NDD) Clinic. complementary medicine - Parkinson Disease, Parkinsonism | Recruiting | St. Mary's University, Twickenham | 100 | 2025-09-19 | 2025-10-03 | |
| Saliva and Extracellular Vesicles for Neurodegenerative Diseases Saliva collection, longitudinal - Neurodegenerative Diseases, Parkinson Disease | Recruiting | Fondazione Don Carlo Gnocchi ETS | 242 | 2025-01-24 | 2025-08-07 | |
| Clinical Efficacy of Intermittent Theta Burst Transcranial Magnetic Stimulation With Different Modes on Parkinson's Disease High-dose iTBS treatment group, Low-dose iTBS treatment group, Sham stimulation group - Parkinsonism, Transcranial Magnetic Stimilation | Not applicable | Enrolling by invitation | Second Affiliated Hospital of Soochow University | 90 | 2025-01-01 | 2026-02-13 |
| A Multimodal Prospective Cohort Study of Parkinsonism Parkinsonism, REM Sleep Behavior Disorder | Recruiting | Ruijin Hospital | 640 | 2024-05-01 | 2026-04-28 | |
| TRANSPARK_LONG: The Diagnostic Value of Early Transcranial Ultrasound in Patients With Extrapyramidal Diseases in a Swedish Population Parkinsonism, Tremor | Completed | Region Skane | 74 | 2024-02-08 | 2025-07-24 | |
| Ultrasound Changes of the Vagus Nerve in Patients With Parkinsonism Ultrasound - Parkinsonism | Unknown | Assiut University | 102 | 2023-12-01 | 2024-02-22 | |
| Efficacy and Safety of Astragalus for Non-motor Symptoms of α-Synucleinopathy Physical therapy group, Astragalus - Parkinsonism | Phase 2 | Unknown | Fujian Medical University Union Hospital | 40 | 2023-10-01 | 2023-09-13 |
| MIBG in Aging and Neurologic Disorders meta-iodobenzylguanidine (MIBG) (123I), 123I-MIBG scintigraphy - Lewy Body Disease, Dementia | Phase 4 | Enrolling by invitation | Mayo Clinic | 50 | 2023-05-08 | 2026-07-30 |
| Head-up Tilt Sleeping to Alleviate Orthostatic Hypotension, Supine Hypertension and Nocturia in Parkinson's Disease Head-up tilt sleeping - Parkinson Disease, Parkinsonism | Not applicable | Unknown | Radboud University Medical Center | 50 | 2023-01-18 | 2024-05-09 |
| Proactive and Integrated Management and Empowerment in Parkinson's Disease (PRIME-UK): A New Model of Care (PRIME-RCT) PRIME Parkinson Care, Usual Care - Parkinsonism | Not applicable | Completed | University of Bristol | 214 | 2022-10-28 | 2025-09-29 |
| Biomarkers in Parkinsonian Syndromes Parkinson Disease, Progressive Supranuclear Palsy | Active not recruiting | Non-profit organization for scientific research in Parkinson's disease and related disorders | 200 | 2022-03-23 | 2026-06-17 | |
| Effects of Music Beat on Motor Function in Individuals At Risk for Psychotic Onset and Schizophrenia Patients Rhythmic auditory stimulation (RAS), no RAS - Schizophrenia, Psychosis | Not applicable | Completed | Dr WANG Shumei | 15 | 2021-08-11 | 2024-11-21 |
| Spinal Cord Stimulation for Parkinsonism Spinal cord stimulation - Parkinsonism | Not applicable | Recruiting | Ruijin Hospital | 50 | 2021-05-01 | 2025-05-09 |
| Prodromal and Overt Parkinson's Disease Epidemiological Study in Brazil Parkinson Disease, Parkinsonism | Unknown | Hospital de Clinicas de Porto Alegre | 8000 | 2021-04-30 | 2023-03-02 | |
| Potential Use of Autologous and Allogeneic Mesenchymal Stem Cells in Patients With Multiple System Atrophy Autologous Adipose Mesenchymal Stem Cell Implantation, Allogeneic Umbilical Cord Mesenchymal Stem Cell Implantation, Allogeneic Umbilical Cord Mesenchymal Stem Cell and Adipose Secretome Implantation - Multiple System Atrophy, Parkinsonism | Not applicable | Unknown | Universitas Indonesia | 15 | 2020-10-05 | 2021-05-06 |
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Parkinsonian Disorders (54) · Parkinson Disease (31) · Supranuclear Palsy, Progressive (12) · Multiple System Atrophy (8) · Lewy Body Disease (7) · Corticobasal Degeneration (5) · REM Sleep Behavior Disorder (5) · Cognitive Dysfunction (4) · Dyskinesias (4) · Psychotic Disorders (4) · Schizophrenia (4) · Dementia (3) · Gait Disorders, Neurologic (3) · Alzheimer Disease (2) · Dementia, Vascular (2)
Basal Ganglia Diseases (54) · Central Nervous System Diseases (54) · Nervous System Diseases (54) · Brain Diseases (53) · Movement Disorders (53) · Neurodegenerative Diseases (37) · Synucleinopathies (33) · Pathological Conditions, Signs and Symptoms (28) · Signs and Symptoms (26) · Neurologic Manifestations (23) · Mental Disorders (17) · Cranial Nerve Diseases (12) · Eye Diseases (12) · Ocular Motility Disorders (12) · Ophthalmoplegia (12)
Transcranial Magnetic Stimulation (3) · Physical Therapy Modalities (2) · Transcranial Direct Current Stimulation (2) · 3-Iodobenzylguanidine (1) · Amantadine (1) · Botulinum Toxins (1) · Complementary Therapies (1) · Droxidopa (1) · Homeopathy (1) · Hypnosis (1) · Iodine-123 (1) · Lasers (1) · Mindfulness (1) · Palliative Care (1) · Radionuclide Imaging (1)
Dr WANG Shumei (3) · Fondazione Europea di Ricerca Biomedica Ferb Onlus (3) · Mayo Clinic (3) · Ruijin Hospital (3) · Radboud University Medical Center (2) · The Cooper Health System (2) · University College, London (2) · Assiut University (1) · Bastyr University (1) · California Pacific Medical Center Research Institute (1) · Chang Gung Memorial Hospital (1) · Corporal Michael J. Crescenz VA Medical Center (1) · Dartmouth-Hitchcock Medical Center (1) · Fondazione Don Carlo Gnocchi ETS (1) · Fujian Medical University Union Hospital (1)
United States (18) · China (6) · Italy (6) · United Kingdom (5) · Hong Kong (3) · Sweden (3) · Greece (2) · Netherlands (2) · Argentina (1) · Austria (1) · Brazil (1) · Egypt (1) · Estonia (1) · France (1) · Germany (1)
Andrea Pilotto, MD (3) · Bradley Boeve, MD (2) · Aleksandar Videnovic, M.D. (1) · Alice Gualerzi, PhD (1) · Allan Wu, M.D. (1) · Allison Brashear, MD (1) · Alysha Bogard, PhD (1) · Andreea Nissenkorn, MD (1) · Andrew McGarry, MD (1) · Angelo Antonini, MD, PhD (1) · Artur F Schuh-Schumacher, Dr. (1) · Benzi M Kluger, MD, MS (1) · Chen Shu, PhD (1) · Emily J Henderson, PhD (1) · Filip Bergquist, MD, PhD (1)
PMID 22550086, PMID 22924536, PMID 24436111, PMID 29560382, PMID 32198310, PMID 33348363, PMID 33408148, PMID 33422890, PMID 33649343, PMID 34006157, PMID 34328563, PMID 34489348, PMID 35186218, PMID 35426173, PMID 35624405, PMID 36844148, PMID 37838080, PMID 37955923, PMID 38166676, PMID 38902546, PMID 39894518, PMID 41254481, PMID 41334626, PMID 41812391, PMID 41814450, PMID 41873211, PMID 42143029
R01AG059417 (1), R01NR016037 (1), R01NS058949 (1), U01NS112010 (1)