23 completed, 5 unknown, 3 terminated, 1 recruiting. 32 Phase 2, 8 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 32 | Completed 23, Unknown 5, Terminated 3, Recruiting 1 |
| Phase 1 | 8 | Completed 6, Terminated 1, Unknown 1 |
| Phase 3 | 3 | Completed 1, Recruiting 1, Unknown 1 |
Follow Paresis: new trials by email Literature Review of Paresis trials Research Report on Paresis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Wereables for Upper Limb Functionality in Hemiparesis WeFun-wearable activated, WeFun-wearable desactivated - Unilateral Cerebral Palsy | Phase 2 / Phase 3 | Recruiting | Universidade da Coruña | 40 | 2024-06-07 | 2025-03-12 |
| Trans Auricular Vagus Nerve Stimulation (taVNS) and Robotic Training for Paralyzed Arm After Stroke In Motion Rehabilitation Robot - Stroke, Hemiparesis | Phase 2 | Completed | Northwell Health | 40 | 2022-09-12 | 2026-10-06 |
| Take Off Pounds After Stroke Trial (TOPS) Partial meal replacement program, Dietary Counseling - Stroke, Obesity | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 38 | 2019-12-01 | 2023-08-23 |
| Investigation of Neural Stem Cells in Ischemic Stroke CTX0E03 Drug Product and delivery device, Placebo - Ischemic Stroke, Chronic Stroke | Phase 2 | Terminated | ReNeuron Limited | 15 | 2018-08-31 | 2021-08-13 |
| Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke Transcutaneous Vagus Nerve Stimulation (tVNS), Sham Transcutaneous Vagus Nerve Stimulation (tVNS) - Stroke, Cerebrovascular Accident (CVA) | Phase 2 | Completed | Northwell Health | 36 | 2018-08-09 | 2021-06-29 |
| Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke Active RAVANS concurrent with arm motor training, Inactive RAVANS concurrent with arm motor training - Stroke, Upper Extremity Paresis | Phase 1 / Phase 2 | Terminated | Massachusetts General Hospital | 6 | 2018-05-17 | 2021-09-21 |
| Evaluation of Electrical Activity Tibial Muscle and Postural Control of Individuals With Hemiparesia Post TDCS Associated With FES Transcranial direct current stimulation (tDCS), Functional electrical stimulation (FES), Sham stimulation - Hemiparesis, Transcranial Direct Current Stimulation | Phase 2 | Unknown | University of Nove de Julho | 2 | 2017-02-01 | 2017-01-04 |
| The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke sham Doublestim, anodal Doublestim - Stroke, Cerebrovascular Accident (CVA) | Phase 1 / Phase 2 | Completed | Northwell Health | 26 | 2016-09-01 | 2021-04-05 |
| The Immediate Effect of Electrical Stimulation Transcranial Direct Current (tDCS) Associated With the Use of FES, in Muscle Activity of the Tibialis Anterior Muscle, Balance and Plantar Pressure Distribution of Individuals With Hemiparesis Due to Stroke Transcranial direct current stimulation (tDCS), Functional electrical stimulation (FES), Sham stimulation - STROKE | Phase 1 / Phase 2 | Completed | University of Nove de Julho | 30 | 2015-01-01 | 2016-10-25 |
| The Baby CHAMP Study (Children With Hemiparesis Arm and Movement Project) Neurorehabilitation therapy with cast, Neurorehabilitation therapy with splint, Neurorehabilitation bimanual - Hemiparesis, Cerebral Palsy | Phase 1 / Phase 2 | Completed | Virginia Polytechnic Institute and State University | 58 | 2015-01-01 | 2022-03-11 |
| Treatment With Xeomin Versus Botox in Children With Spastic Equine and Equinovarus Foot Deformation in Pediatric Cerebral Palsy Xeomin, Botox® - Cerebral Palsy, Spastic Paraplegia and Hemiparesis | Phase 2 | Completed | Merz Pharmaceuticals GmbH | 64 | 2014-07-01 | 2017-01-26 |
| Pilot Investigation of Stem Cells in Stroke Phase II Efficacy CTX DP - Ischaemic Stroke, Cerebral Infarction | Phase 2 | Completed | ReNeuron Limited | 23 | 2014-06-01 | 2018-07-23 |
| Music Therapy for The Rehabilitation of Upper Limb With Stroke Patients Therapeutic Instrumental Music Performance - Hemiparesis | Phase 2 | Completed | Anglia Ruskin University | 10 | 2014-01-01 | 2016-01-05 |
| Children With Hemiparesis Arm and Hand Movement Project (CHAMP Study) Variations in Pediatric Constraint-Induced Movement Therapy (P-CIMT) versus usual and customary rehabilitation - Hemiparesis, Cerebral Palsy | Phase 2 | Completed | Virginia Polytechnic Institute and State University | 124 | 2013-07-01 | 2022-03-25 |
| Robot Therapy for Rehabilitation of Hand Movement After Stroke HEXORR - Stroke, Movement Disorders | Phase 2 | Completed | The Catholic University of America | 15 | 2012-10-04 | 2020-09-03 |
| Botulinum Toxin Type A (BT-A) in Hemiplegic Shoulder Pain Versus Steroid BT-A (Dysport 500U), Triamcinolone acetonide - Stroke, Hemiparesis | Phase 2 | Unknown | The Foundation Institute San Raffaele G. Giglio of Cefalù | 52 | 2012-01-01 | 2011-11-17 |
| Video-based Training for Rehabilitation of Upper Limb Functions After Stroke verum group, Placebo group - Stroke, Upper Limb Paresis | Phase 2 | Terminated | RWTH Aachen University | 100 | 2011-09-01 | 2015-09-23 |
| Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery tDCS: noninvasive brain stimulation, Constraint induced movement therapy (CIMT), Sham tDCS: placebo noninvasive brain stimulation - Stroke | Phase 1 / Phase 2 | Completed | The Cleveland Clinic | 67 | 2011-07-01 | 2020-07-16 |
| AMES Treatment of the Impaired Leg in Chronic Stroke Patients AMES- Leg treatment - Stroke, Cerebrovascular Accident | Phase 1 / Phase 2 | Unknown | AMES Technology | 22 | 2011-01-01 | 2016-12-08 |
| Does More Practice Improve Arm Movement After Stroke? Intensive task-specific upper extremity rehabilitation - Stroke | Phase 2 | Completed | Washington University School of Medicine | 85 | 2010-05-01 | 2017-02-24 |
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Stroke (22) · Cerebral Palsy (5) · Cerebral Infarction (2) · Ischemic Stroke (2) · Brain Diseases (1) · Brain Injuries (1) · Bronchiolitis Obliterans Syndrome (1) · Cerebrovascular Disorders (1) · Encephalitis (1) · Epilepsy (1) · Fatigue (1) · Hemiplegia (1) · Intervertebral Disc Displacement (1) · Motor Activity (1)
Nervous System Diseases (32) · Pathological Conditions, Signs and Symptoms (32) · Signs and Symptoms (32) · Neurologic Manifestations (31) · Central Nervous System Diseases (30) · Brain Diseases (29) · Cardiovascular Diseases (24) · Vascular Diseases (24) · Cerebrovascular Disorders (23) · Brain Damage, Chronic (5) · Musculoskeletal Diseases (3) · Brain Infarction (2) · Brain Ischemia (2) · Infarction (2) · Ischemia (2)
Transcranial Direct Current Stimulation (3) · Botulinum Toxins, Type A (2) · Stroke Rehabilitation (2) · Constraint Induced Movement Therapy (1) · Cycloserine (1) · Fluoridation (1) · Modafinil (1) · Music Therapy (1) · Nutrition Assessment (1) · Octagam (1) · POLR1G protein, human (1) · Physical Therapy Modalities (1) · Resistance Training (1) · Saline Solution (1) · Splints (1)
Northwell Health (3) · US Department of Veterans Affairs (3) · ReNeuron Limited (2) · University of Nove de Julho (2) · Virginia Polytechnic Institute and State University (2) · AMES Technology (1) · Anglia Ruskin University (1) · Beth Israel Deaconess Medical Center (1) · Burke Rehabilitation Hospital (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Massachusetts General Hospital (1) · Merz Pharmaceuticals GmbH (1) · MetroHealth Medical Center (1) · New York Presbyterian Hospital (1) · RWTH Aachen University (1)
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Armin Curt, Prof. (1) · Barry Oken, MD (1) · Bruce T Volpe, MD (1) · Catherine E Lang, PT, PhD (1) · Christian G Bien, M.D. (1) · Daniel M Corcos, PhD (1) · Danielle M Kerkovitch, Ph.D. (1) · David Wolff, Ph.D. Special Assistant to the Director (1) · Edward Taub, PhD (1) · Ela B Plow, PhD PT (1) · Elliot Roth, MD (1) · Ferdinand Binkofski, Prof. Dr. med. (1) · Giuseppe Galardi, Dr (1) · Jayme S Knutson, PhD (1) · Keith W Muir (1)
PMID 19520987, PMID 19531608, PMID 24119615, PMID 24382580, PMID 25938519, PMID 26752061, PMID 27724916, PMID 28643570, PMID 30782701, PMID 32232101, PMID 33175411, PMID 34649982, PMID 34899170, PMID 35130557, PMID 36772802, PMID 37231793, PMID 38419030, PMID 41541089
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