5 completed, 1 enrolling by invitation, 1 terminated, 1 unknown. 3 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 2 | 3 | Completed 1, Terminated 1, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Long-Term Safety Study of CTX0E03 in Subjects Who Completed PISCES III Study Non Interventional long term safety follow up - Ischemic Stroke | Enrolling by invitation | ReNeuron Limited | 9 | 2022-11-01 | 2023-03-31 | |
| Investigation of Neural Stem Cells in Ischemic Stroke CTX0E03 Drug Product and delivery device, Placebo - Ischemic Stroke, Chronic Stroke | Phase 2 | Terminated | ReNeuron Limited | 15 | 2018-08-31 | 2021-08-13 |
| An Ischaemic Stroke Observational Study Stroke | Completed | ReNeuron Limited | 39 | 2017-05-01 | 2017-12-05 | |
| Safety and Tolerability of hRPC in Retinitis Pigmentosa hRPC - Retinitis Pigmentosa | Phase 1 / Phase 2 | Unknown | ReNeuron Limited | 29 | 2015-12-01 | 2023-07-06 |
| Pilot Investigation of Stem Cells in Stroke Phase II Efficacy CTX DP - Ischaemic Stroke, Cerebral Infarction | Phase 2 | Completed | ReNeuron Limited | 23 | 2014-06-01 | 2018-07-23 |
| Safety Trial Of CTX Cells In Patients With Lower Limb Ischaemia CTX DP - Peripheral Arterial Disease | Phase 1 | Completed | ReNeuron Limited | 5 | 2014-04-01 | 2018-01-31 |
| Observational Study of Ischaemic Stroke Stroke, Motor Activity | Completed | ReNeuron Limited | 110 | 2014-02-01 | 2016-12-19 | |
| Pilot Investigation of Stem Cells in Stroke CTX0E03 neural stem cells - Stroke | Phase 1 | Completed | ReNeuron Limited | 11 | 2010-06-01 | 2023-07-06 |
Cerebral Infarction (3) · Ischemic Stroke (3) · Stroke (3) · Brain Diseases (2) · Cardiovascular Diseases (2) · Paresis (2) · Vascular Diseases (2) · Brain Infarction (1) · Central Nervous System Diseases (1) · Cerebrovascular Disorders (1) · Motor Activity (1) · Nervous System Diseases (1) · Peripheral Arterial Disease (1) · Retinitis Pigmentosa (1)
United Kingdom (6) · United States (3) · Spain (1)
Amy Miller, RPh, PharmD (1) · Jason Comander, MD (1) · Jill JF Belch, MBChB (1) · Keith W Muir (1) · Richard Beckman, MD (1) · Vince Holmes (1)
PMID 26752061, PMID 25938519, PMID 24725992, PMID 27497862, PMID 35130557, PMID 38419030, PMID 41541089