3 completed, 3 unknown, 1 terminated, 1 withdrawn. 5 Phase 3, 4 Phase 2, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Unknown 2, Completed 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
Follow this drug Literature Review of Octagam trials Research Report on Octagam
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IgIV Plus Prednisone vs High-dose Dexamethasone for ITP Neofordex®, Intravenous immunoglobulins - Immune Thrombocytopenia (ITP) | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 272 | 2022-04-07 | 2023-09-11 |
| IVIG in Patients With Severe COVID-19 Requiring Mechanical Ventilation IVIG - Covid19, SARS-CoV Infection | Phase 4 | Unknown | Sharp HealthCare | 10 | 2020-11-01 | 2020-11-04 |
| Study of SOC Plus IVIG Compared to SOC Alone in the Treatment of COVID-19 Octagam - Sars-CoV2 | Phase 4 | Completed | George Sakoulas, MD | 34 | 2020-04-28 | 2021-06-25 |
| Autologous Transplant To End NMO Spectrum Disorder Rituximab, Cyclophosphamide, Mesna - Neuromyelitis Optica, Devic's Disease | Phase 2 / Phase 3 | Withdrawn | Northwestern University | 2019-11-01 | 2019-11-20 | |
| Cardiac Safe Transplants for Systemic Sclerosis Rituximab, Fludarabine, Cyclophosphamide - Systemic Sclerosis, Scleroderma | Phase 2 / Phase 3 | Terminated | Northwestern University | 9 | 2018-05-17 | 2020-08-12 |
| Ig PRx in AECOPD: Pilot Study Intravenous immunoglobulin (IVIG), Normal Saline - Chronic Obstructive Pulmonary Disease | Phase 2 | Completed | Ottawa Hospital Research Institute | 48 | 2016-09-01 | 2019-11-27 |
| Effect of Intravenous Immunglobulin (IVIG) After Myocardial Infarction Octagam (IVIG) - Acute Myocardial Infarction | Phase 3 | Completed | Oslo University Hospital | 62 | 2007-02-01 | 2014-01-27 |
| Efficacy of Tacrolimus and I.V.-Immunoglobulins in Rasmussen Encephalitis Tacrolimus, i.v. immunoglobulins - Rasmussen Encephalitis | Phase 2 / Phase 3 | Unknown | University Hospital, Bonn | 16 | 2002-11-01 | 2009-04-10 |
COVID-19 (2) · Coronavirus Infections (1) · Encephalitis (1) · Epilepsy (1) · Heart Failure (1) · Myocardial Infarction (1) · Neuromyelitis Optica (1) · Paresis (1) · Pulmonary Disease, Chronic Obstructive (1) · Purpura, Thrombocytopenic, Idiopathic (1) · Scleroderma, Diffuse (1) · Scleroderma, Systemic (1) · Severe Acute Respiratory Syndrome (1)
Northwestern University (2) · Assistance Publique - Hôpitaux de Paris (1) · George Sakoulas, MD (1) · Oslo University Hospital (1) · Ottawa Hospital Research Institute (1) · Sharp HealthCare (1) · University Hospital, Bonn (1)
United States (4) · Canada (1) · France (1) · Germany (1) · Norway (1)
George Sakoulas, MD (2) · Richard Burt, MD (2) · Christian G Bien, M.D. (1) · Juthaporn Cowan, MD, PhD, FRCPC (1) · Lars Gullestad, MD, PhD (1)