35 completed, 12 unknown, 4 recruiting, 3 not yet recruiting. 29 Not applicable, 5 Phase 2, 3 Phase 1, 3 Phase 4, 1 Early Phase 1.
Follow Sleep Bruxism: new trials by email Literature Review of Sleep Bruxism trials Research Report on Sleep Bruxism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Orofacial Pain and Oral Health-Related Quality of Life in Musicians in German Amateur Orchestras Questionaire - Orofacial Pain, Sleep Bruxism | Recruiting | University Medical Center Goettingen | 400 | 2026-09-01 | 2026-09-04 | |
| Bruxism Induced by Obstructive Sleep Apnoea. Upper airway volume assessment using Cone-Beam Computed Tomography (CBCT) and Polysomnography, Upper airway volume assessment using Cone-Beam Computed Tomography (CBCT) - Sleep Apnea Syndrome, Obstructive, Bruxism, Sleep-Related | Not yet recruiting | Wroclaw Medical University | 80 | 2026-09-01 | 2026-07-22 | |
| Effect of Night Guard Use on Masseter Muscle Thickness in Children With Bruxism Occlusal Splint (Night Guard) - Bruxism, Bruxism, Sleep-Related | Not applicable | Recruiting | Nigde Omer Halisdemir University | 20 | 2026-03-15 | 2026-04-29 |
| 3D-Printed vs Conventional Acrylic Stabilization Splints in Young Adults With Bruxism and Temporomandibular Disorders: A Randomized Trial 3D-Printed Occlusal Splint (Voco V-Print), Conventional Acrylic Occlusal Splint - Bruxism, Sleep | Not applicable | Recruiting | Baskent University | 44 | 2026-01-12 | 2026-02-25 |
| Bruxism Therapy of Facial Pain Electromyographic analysis of the masseter muscle using the Diabruxo® device (Biotech-Novations, Sanremo, Italy). - Bruxism, Bruxism, Sleep-Related | Not applicable | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 42 | 2026-01-12 | 2026-06-17 |
| Comparison of Dry Needling and Two Botulinum Toxins for Bruxism Dry Needling (DN), PrabotulinumtoxinA, Abobotulinumtoxina - Bruxism, Sleep Bruxism, Adult | Not applicable | Completed | Recep Tayyip Erdogan University | 72 | 2026-01-09 | 2026-05-20 |
| Changes in Electromyographic Activity in Aligner Treatment of Adult Patients With and Without Nocturnal Bruxism Bruxoff ® - Sleep Bruxism, Masseter Muscle Hypertrophy | Not applicable | Suspended | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 22 | 2025-10-31 | 2025-08-27 |
| Surface Electromyography in the Detection and Assessment of Bruxism sEMG - Bruxism, Sleep | Not yet recruiting | Escoles Universitaries Gimbernat | 54 | 2025-10-01 | 2025-07-17 | |
| Manual Therapy in Vagus Nerve Neuromodulation for the Treatment of Bruxism Autonomic nervous system intervention, Slight finger pressure - Bruxism, Sleep | Not applicable | Not yet recruiting | Escoles Universitaries Gimbernat | 40 | 2025-10-01 | 2025-07-24 |
| Diaphragmatic Breathing for Sleep Bruxism in Adults: A Randomized Controlled Trial Diaphragmatic Breathing Program, Neutral Music Listening - Bruxism, Bruxism, Sleep-Related | Not applicable | Completed | University of Monastir | 100 | 2025-09-15 | 2025-11-19 |
| Synchronous vs Asynchronous Telerehabilitation for Bruxism Synchronous Telerehabilitation Protocol, Asynchronous Telerehabilitation Protocol - Bruxism, Sleep Bruxism | Not applicable | Completed | Gazi University | 34 | 2025-08-01 | 2026-09-18 |
| Changes in Bruxism Activity After Periodontal Treatment in Patients With Periodontitis Non-Surgical Periodontal Therapy (Step 1 & 2), Supragingival Plaque Removal and Polishing - Periodontitis, Bruxism | Not applicable | Completed | University of Siena | 40 | 2025-06-27 | 2025-11-28 |
| Electromyographic Assessment of Sleep Bruxism in Patients With Stage III and IV Periodontitis Surface Electromyography (dia-BRUXO) - Bruxism, Periodontitis | Completed | University of Siena | 40 | 2025-06-27 | 2025-09-04 | |
| Low-Level Laser Therapy Versus Occlusal Splint Therapy for Bruxism in Children Low-Level Laser Therapy (LLLT), Occlusal Splint - Bruxism, Sleep Bruxism | Not applicable | Completed | Ain Shams University | 30 | 2025-05-01 | 2026-10-16 |
| Smartwatch Analysis of Sleep Bruxism Smartwatch-based Sleep Monitoring - Bruxism, Sleep-Related | Completed | Cappadocia University | 62 | 2025-01-01 | 2026-03-09 | |
| Efficacy of Botulinum Toxin and Marjoram Oil Applications in Bruxism Botox administration, Aromatherapy, Clinical evaluation - Bruxism, Sleep | Not applicable | Completed | Bezmialem Vakif University | 30 | 2024-10-11 | 2025-09-19 |
| Effect of Marjoram, Vetiver, and Lavender Oil in the Treatment of Bruxism Aromatherapy with Essential Oil Blend (Lavender, Marjoram, Vetiver), Carrier Oil (Sesame Oil) - Bruxism, Bruxism, Sleep | Not applicable | Active not recruiting | Necmettin Erbakan University | 64 | 2024-09-02 | 2026-07-02 |
| A Sensor-enhanced Mouth Guard to Quantitatively Measure Bite Compression Forces. Bruxism, Sleep-Related | Terminated | Otis Dental, LLC | 2 | 2024-08-05 | 2026-03-03 | |
| Pain and Mobility in Children With Sleep Bruxism Bruxism, Sleep | Completed | Karabuk University | 80 | 2024-06-15 | 2025-04-22 | |
| mRNA Expression and Genetic Polymorphisms Affecting DRD3 (rs6280) and HTR2A (rs6313) in Bruxism Genetic polymorphism - Bruxism | Unknown | University of Monastir | 169 | 2024-06-02 | 2024-06-13 |
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Bruxism (23) · Temporomandibular Joint Disorders (7) · Sleep Wake Disorders (5) · Sleep Apnea Syndromes (3) · Sleep Apnea, Obstructive (3) · Sleep Initiation and Maintenance Disorders (3) · Anxiety Disorders (2) · Cardiovascular Diseases (2) · Disease (2) · Masticatory Muscles, Hypertrophy of (2) · Periodontitis (2) · Airway Remodeling (1) · Chronic Pain (1) · Depression (1)
Mental Disorders (62) · Nervous System Diseases (62) · Stomatognathic Diseases (62) · Tooth Diseases (62) · Parasomnias (61) · Sleep Wake Disorders (57) · Bruxism (39) · Behavior (25) · Habits (23) · Pathological Conditions, Signs and Symptoms (11) · Muscular Diseases (8) · Musculoskeletal Diseases (8) · Neurologic Manifestations (8) · Signs and Symptoms (8) · Craniomandibular Disorders (7)
Occlusal Splints (7) · Polysomnography (7) · Botulinum Toxins, Type A (3) · Aromatherapy (2) · lemon balm leaf extract (2) · Carrier State (1) · Counseling (1) · Dry Needling (1) · Educational Status (1) · Electromyography (1) · Food (1) · Gabapentin (1) · Gravidity (1) · Homeopathy (1) · Lasers (1)
Federal University of Pelotas (6) · University of Nove de Julho (4) · Wroclaw Medical University (4) · CES University (2) · Escoles Universitaries Gimbernat (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · Hasan Kalyoncu University (2) · Karabuk University (2) · Universidade Federal do Rio de Janeiro (2) · University of Monastir (2) · University of Siena (2) · Aesyra SA (1) · Ain Shams University (1) · Ankara University (1) · Ankara Yildirim Beyazıt University (1)
Turkey (Türkiye) (16) · Brazil (9) · Italy (5) · Poland (4) · Germany (3) · United States (3) · Canada (2) · Spain (2) · Colombia (1) · Egypt (1) · France (1) · Iran (1) · Netherlands (1) · Saudi Arabia (1) · South Korea (1)
Nicola Discepoli, DDS, PhD (2) · Aaron Glick, DDS (1) · Andrea G. Antonio, Adjunct Professor (1) · Aysenur Tuncer (1) · Aysenur Tuncer, PhD (1) · Azamsadat Madani, Dr (1) · Brigitte Ohlmann, Prof. Dr. (1) · Claudia C Restrepo, PHD (1) · Claudia Restrepo, DDS (1) · Dominik A Ettlin, MD, DMD (1) · Ebrahim Abdollahian, Dr (1) · Elifhan Alagoz, Asst. Prof. (1)
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