3 completed, 3 recruiting, 2 unknown, 2 withdrawn. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 3, Recruiting 3, Unknown 2, Withdrawn 2, Not yet recruiting 1, Terminated 1 |
Follow Osteomyelitis: new trials by email Literature Review of Osteomyelitis trials Research Report on Osteomyelitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Oral Antibiotics For Bone Infections of the Leg and Foot Oral Beta-Lactam Antibiotic, Oral Non-Beta-Lactam Antibiotic - Osteomyelitis of Lower Extremities, Osteomyelitis - Foot | Phase 4 | Recruiting | Michael Garron Hospital | 1418 | 2026-02-26 | 2026-03-27 |
| Antibiotic Impregnated Beads in Osteomyelitis Antibiotic loaded calcium sulfate beads, Calcium sulfate beads (sham beads) - Osteomyelitis of the Foot, Antibiotic Impregnated Beads | Phase 4 | Not yet recruiting | University of Arizona | 100 | 2025-09-01 | 2025-07-18 |
| Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections Trimethoprim Sulfamethoxazole - Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute | Phase 4 | Recruiting | Indiana University | 100 | 2025-05-20 | 2026-07-29 |
| BonE and Joint Infections - Simplifying Treatment in Children Trial Oral cefalexin only, IV cefazolin or IV flucloxacillin followed by oral cefalexin - Bone Infection, Septic Arthritis | Phase 4 | Recruiting | Murdoch Childrens Research Institute | 214 | 2021-06-01 | 2026-10-27 |
| Oral-only Antibiotics for Bone and Joint Infections in Children Oral co-amoxiclav or oral dicloxacillin only, IV ceftriaxon followed by oral co-amoxiclav or oral dicloxacillin - Osteomyelitis, Septic Arthritis | Phase 4 | Completed | Copenhagen University Hospital, Rigshospitalet | 180 | 2020-09-15 | 2025-04-13 |
| Ceftriaxone as Home IV for Staph Infections Ceftriaxone, Usual Antibiotics (Cloxacillin, Cefazolin, Daptomycin) - Staphylococcal Infections, Osteomyelitis | Phase 4 | Unknown | Vancouver Island Health Authority | 310 | 2019-07-11 | 2019-10-28 |
| Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections Dalbavancin, Vancomycin - Bone Infection, Osteomyelitis | Phase 4 | Completed | Infectious Diseases Physicians, Inc. | 41 | 2018-01-25 | 2023-10-03 |
| Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics Rifampin, Riboflavin Placebo - Osteomyelitis, Diabetes | Phase 4 | Completed | VA Office of Research and Development | 843 | 2018-01-22 | 2026-04-20 |
| CERAMENT™|G - Bone Healing and Re-infection Prophylaxis Cerament G - Osteomyelitis | Phase 4 | Unknown | Dr. Olivier Borens | 15 | 2014-05-01 | 2015-12-02 |
| Ceftaroline in the Treatment of Bone and Joint Infections Ceftaroline - Osteomyelitis, Joint Infections | Phase 4 | Withdrawn | Orlando Health, Inc. | 2013-04-01 | 2014-08-07 | |
| Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients Vancomycin, Ceftaroline, Daptomycin - Health Care Associated Pneumonia, Osteomyelitis/Septic Arthritis | Phase 4 | Terminated | Henry Ford Health System | 100 | 2011-10-01 | 2023-05-03 |
| a Randomized Controlled Trial Comparing Medical and Medical-surgical Treatment in Diabetic Foot Osteomyelitis Medical/surgical treatment versus medical treatment - Diabetic Foot | Phase 4 | Withdrawn | Assistance Publique - Hôpitaux de Paris | 2008-06-01 | 2012-09-17 |
Arthritis, Infectious (6) · Abscess (1) · Bacteremia (1) · Central Nervous System Infections (1) · Diabetes Mellitus (1) · Diabetic Foot (1) · Endocarditis (1) · Mastoiditis (1) · Orbital Cellulitis (1) · Peritonsillar Abscess (1) · Retropharyngeal Abscess (1) · Staphylococcal Infections (1)
Bone Diseases (12) · Bone Diseases, Infectious (12) · Infections (12) · Musculoskeletal Diseases (12) · Arthritis (6) · Joint Diseases (6) · Bacterial Infections (2) · Bacterial Infections and Mycoses (2) · Cardiovascular Diseases (2) · Endocrine System Diseases (2) · Inflammation (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Skin and Connective Tissue Diseases (2) · Suppuration (2)
Cefazolin (3) · Daptomycin (3) · Ceftaroline (2) · Vancomycin (2) · Amoxicillin-Potassium Clavulanate Combination (1) · Ceftriaxone (1) · Cloxacillin (1) · Dicloxacillin (1) · Injections (1) · Linezolid (1) · Monobactams (1) · Nafcillin (1) · Rifampin (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1) · dalbavancin (1)
Assistance Publique - Hôpitaux de Paris (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dr. Olivier Borens (1) · Henry Ford Health System (1) · Indiana University (1) · Infectious Diseases Physicians, Inc. (1) · Michael Garron Hospital (1) · Murdoch Childrens Research Institute (1) · Orlando Health, Inc. (1) · University of Arizona (1) · VA Office of Research and Development (1) · Vancouver Island Health Authority (1)
United States (5) · Canada (2) · Australia (1) · Denmark (1) · Ireland (1) · New Zealand (1) · Switzerland (1)
Allan Bybeck Nielsen, MD (1) · Amanda Gwee, PhD (1) · Donald Poretz, MD (1) · Eric Partlow, MD, FRCPC (1) · James Wood, MD (1) · Jose Vazquez, M.D. (1) · Mark R. Wallace, MD (1) · Mary T Bessesen, MD (1) · Ulrikka Nygaard, Ass Prof PhD (1)