12 terminated. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Terminated 12 |
Follow Obstructive Sleep Apnea: new trials by email Literature Review of Obstructive Sleep Apnea trials Research Report on Obstructive Sleep Apnea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Obstructive Sleep Apnea Treatment on Cardiovascular Events in Patients With Acute Cardiogenic Pulmonary Edema: CPAP-CARE STUDY. CPAP, Nasal Strips - Obstructive Sleep Apnea, Pulmonary Edema Cardiac Cause | Phase 4 | Terminated | University of Sao Paulo | 150 | 2019-04-01 | 2024-06-07 |
| Evaluation of Modafinil vs Placebo for Treatment of Anesthesia Delayed Emergence in Obstructive Sleep Apnea Modafinil, Placebo - Obstructive Sleep Apnea, Delayed Emergence From Anesthesia | Phase 4 | Terminated | Milton S. Hershey Medical Center | 105 | 2016-02-01 | 2019-06-20 |
| Inspire® Upper Airway Stimulation System Inspire® Upper Airway Stimulation (UAS) System - Obstructive Sleep Apnea | Phase 4 | Terminated | Inspire Medical Systems, Inc. | 16 | 2015-08-01 | 2016-08-11 |
| The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation Normal Saline, Dexmedetomidine - Adenotonsillar Hypertrophy, Obstructive Sleep Apnea | Phase 4 | Terminated | Massachusetts Eye and Ear Infirmary | 92 | 2015-03-01 | 2020-04-09 |
| Post-operative Pain Control After Pediatric Adenotonsillectomy Ibuprofen, Hydrocodone-Acetaminophen - Recurrent Tonsillitis, Obstructive Sleep Apnea | Phase 4 | Terminated | Emory University | 45 | 2014-11-01 | 2018-04-25 |
| Intermittent Hypoxia 2: Cardiovascular and Metabolism Placebo, Valsartan, Amlodipine - Hypoxia, Sleep Apnea | Phase 4 | Terminated | University Hospital, Grenoble | 12 | 2013-08-07 | 2018-12-31 |
| Inhaled Fluticasone Effects on Upper Airway Patency in Obstructive Lung Disease Inhaled Fluticasone Propionate - Asthma, Chronic Obstructive Pulmonary Disease | Phase 4 | Terminated | VA Office of Research and Development | 25 | 2013-03-12 | 2020-02-05 |
| FAST as a Treatment for Obstructive Sleep Apnea Encore Tongue Suspension System - Obstructive Sleep Apnea | Phase 4 | Terminated | Siesta Medical, Inc. | 5 | 2012-05-01 | 2017-02-24 |
| Effect of Montelukast Therapy in Obstructive Sleep Apnea(OSA) Children Montelukast - Obstructive Sleep Apnea | Phase 4 | Terminated | University of Chicago | 64 | 2010-07-01 | 2019-05-03 |
| Burden of Obstructive Sleep Apnea in Stroke (BOSAST) CPAP, CPAP at sub-therapeutic pressure - Stroke, Obstructive Sleep Apnea | Phase 4 | Terminated | University of California, San Diego | 3 | 2009-08-01 | 2016-04-04 |
| Effects of Continuous Positive Airway Pressure (CPAP) in Heart Remodeling by Magnetic Resonance Imaging (MRI) CPAP, No treatment - Obstructive Sleep Apnea | Phase 4 | Terminated | University of Sao Paulo | 24 | 2007-07-01 | 2014-11-18 |
| Polycystic Ovary Syndrome (PCOS) and Sleep Apnea continuous positive airway pressure (CPAP), depot leuprolide plus estrogen/progestin replacement, pioglitazone - Polycystic Ovary Syndrome, Obstructive Sleep Apnea | Phase 4 | Terminated | University of Chicago | 37 | 2003-09-01 | 2023-03-21 |
Sleep Apnea, Obstructive (12) · Sleep Apnea Syndromes (2) · Tonsillitis (2) · Agnosia (1) · Asthma (1) · Cardiovascular Diseases (1) · Delayed Emergence from Anesthesia (1) · Drug-Related Side Effects and Adverse Reactions (1) · Fatigue (1) · Glucose Intolerance (1) · Heart Failure (1) · Hypoxia (1) · Insulin Resistance (1) · Metabolic Syndrome (1) · Polycystic Ovary Syndrome (1)
Apnea (12) · Dyssomnias (12) · Nervous System Diseases (12) · Respiration Disorders (12) · Respiratory Tract Diseases (12) · Sleep Disorders, Intrinsic (12) · Sleep Wake Disorders (12) · Sleep Apnea Syndromes (10) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (3) · Cardiovascular Diseases (2) · Infections (2) · Otorhinolaryngologic Diseases (2) · Pathologic Processes (2) · Pharyngeal Diseases (2)
Amlodipine (1) · Continuous Positive Airway Pressure (1) · Dexmedetomidine (1) · Drug Delivery Systems (1) · Estrogens (1) · Ibuprofen (1) · Leuprolide (1) · Modafinil (1) · Pioglitazone (1) · Saline Solution (1) · Sodium Chloride (1) · Valsartan (1) · acetaminophen, hydrocodone drug combination (1) · montelukast (1) · oxycodone-acetaminophen (1)
University of Chicago (2) · University of Sao Paulo (2) · Emory University (1) · Inspire Medical Systems, Inc. (1) · Massachusetts Eye and Ear Infirmary (1) · Milton S. Hershey Medical Center (1) · Siesta Medical, Inc. (1) · University Hospital, Grenoble (1) · University of California, San Diego (1) · VA Office of Research and Development (1)
United States (8) · Brazil (2) · Belgium (1) · France (1) · Germany (1)
Andrew Goldberg, MD (1) · Armin Steffen, PD Dr. med. (1) · Clemens Heiser, Dr. med. (1) · David A Ehrmann, M.D. (1) · Esra Tasali, M.D. (1) · Eve Van Cauter, Ph.D. (1) · Joachim T Maurer, OA Dr. med. (1) · Joel Dimsdale, MD (1) · Leila Gozal, MD (1) · Luciano F Drager, MD, PhD (1) · Makara Cayer, MD (1) · Mihaela Teodorescu, MD (1) · Olivier Vanderveken, Prof. dr. (1) · Renaud RT Tamisier, PhD (1) · Roy Rajan, MD (1)
PMID 18172212, PMID 18647805, PMID 21123449, PMID 23019248
R01HL075079 (1)