50 completed, 11 unknown, 5 terminated, 3 recruiting. 24 Not applicable, 16 Phase 3, 15 Phase 2, 15 Phase 4, 3 Phase 1.
Follow Estrogens: new trials by email Literature Review of Estrogens trials Research Report on Estrogens
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Menopausal Hormones and Sympathetic Activation Estrogen, Placebo - Perimenopausal Women | Phase 4 | Not yet recruiting | University of Delaware | 80 | 2026-09-01 | 2026-03-27 |
| Effects of Estrogen Therapy on Lipid Metabolism and Insulin Sensitivity in Hypogonadal Women Estrogen - Female Hypogonadism | Not applicable | Active not recruiting | Khyber Medical University Peshawar | 30 | 2025-12-04 | 2026-09-15 |
| Sleeping Through Menopause Estrogens and Progestogens, Cognitive behavioral therapy for insomnia (CBTi), and circadian rhythm therapy - Menopause, Insomnia | Phase 4 | Not yet recruiting | VU University of Amsterdam | 222 | 2025-10-01 | 2025-08-24 |
| Early Neurovascular Adaptations in Aging Women Norepinephrine, Isoproterenol, Acetylcholine - Women, Sympathetic Nervous System | Early Phase 1 | Recruiting | University of Missouri-Columbia | 64 | 2024-09-20 | 2025-11-26 |
| A Real-World Study Comparing the Efficacy of Different Treatment Regimens for Early Missed Abortion Control group, Conventional dose of estrogen, High-dose estrogen - Missed Abortion, Early Pregnancy Failure | Not applicable | Recruiting | The Third Xiangya Hospital of Central South University | 580 | 2024-01-01 | 2026-02-20 |
| GRACE-trial: a Randomized Active-controlled Trial for vulvovaGinal atRophy in breAst Cancer Patients on Endocrine Therapy. Estrogen, dehydroepiandrosterone, Estrogen + probiotics - Vulvovaginal Atrophy, Breast Cancer | Phase 4 | Completed | University Hospital, Ghent | 31 | 2022-03-21 | 2026-08-13 |
| Micronized Progesterone Versus Norethisterone Acetate in Combination With Estrogen as Menopausal Hormone Therapy Micronized progesterone in continuous combination with oral estrogen, Norethisterone acetate in continuous combination with oral estrogen - Menopausal Symptoms | Phase 3 | Recruiting | Angelica Lindén Hirschberg | 520 | 2022-03-15 | 2024-06-04 |
| Impact of Exogenous Estrogens on Cotisol Levels During Synacthen Stimulation Estrogen - Adrenal Insufficiency, Hypogonadism Female | Not applicable | Unknown | Copenhagen University Hospital, Rigshospitalet | 20 | 2022-01-01 | 2022-03-31 |
| Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGW Truvada alone, Truvada plus Leuprolide 11.25mg intramuscular injection, Truvada plus Estradiol 1 mg - HIV, Prophylaxis | Phase 1 | Completed | Johns Hopkins University | 13 | 2021-03-01 | 2026-04-06 |
| The Relationship of Phthalate Exposure During Pregnancy and Preeclampsia test Phthalates, estrogen and progesterone - Phthalate Exposure, Preeclampsia | Completed | Second Affiliated Hospital of Wenzhou Medical University | 60 | 2021-01-01 | 2022-11-29 | |
| An Open Labeled RCT on the Effect of Additional hCG Injection for LPS on Pregnancy Outcomes in IHH Patients Additional hCG injection, estrogen and dydrogesterone - Luteal Phase Deficiency, Luteal Phase Support | Not applicable | Unknown | Fudan University | 46 | 2021-01-01 | 2024-08-07 |
| Feminizing Hormone Therapy and the Rectal Mucosa Immune Environment in Transgender Women Estrogen, Estrogen plus Progesterone - HIV Prevention | Completed | Emory University | 285 | 2020-10-01 | 2025-06-17 | |
| Clinical Study of in Situ Regeneration of Endometrium CBD-bFGF, Collagen/BMMNCs, Estrogen - Infertility, Female, of Uterine Origin, Endometrial Fibrosis | Phase 1 / Phase 2 | Unknown | Yali Hu | 345 | 2020-04-29 | 2022-09-28 |
| Postprandial Lipidemia After a Meal With Different Types of Fat, Estrogen Treatment, Age and Gender in Healthy Subjects Estrogens, Placebo - Menopause | Not applicable | Withdrawn | Herning Hospital | 2019-08-10 | 2024-10-16 | |
| Fertility and Ovarian Reserve Function in the Patient With Inflammatory Bowel Disease Anti Mueller hormone, Estrogen, Follicle-Stimulating Hormone - Fertility Disorders, Ovarian Reserve Function | Not applicable | Unknown | Sixth Affiliated Hospital, Sun Yat-sen University | 80 | 2017-05-01 | 2017-09-01 |
| The Anabolic Effects of Estrogen on Skeletal Muscles Exercise + Estrogen, Exercise + Placebo - Estrogen Supplementation | Not applicable | Completed | University of Aarhus | 31 | 2017-01-01 | 2019-09-27 |
| Subtypes of Provoked Vestibulodynia Topical hormonal cream (estrogen), Pelvic floor physical therapy, Low Level Laser therapy - Provoked Localized Vulvodynia | Completed | Meir Medical Center | 113 | 2016-11-30 | 2022-04-08 | |
| Interest of Estrogen Scheduling Before Ovarian Stimulation With Corifollitropin Alfa Estrogens - Infertility | Phase 3 | Completed | Centre Hospitalier Intercommunal Creteil | 334 | 2016-11-04 | 2023-02-08 |
| The Efficacy of G-CSF Against Adhesion Reformation After Hysteroscopic Adhesiolysis G-CSF, Normal saline, hormone therapy - Intrauterine Adhesion | Not applicable | Unknown | Sir Run Run Shaw Hospital | 240 | 2016-08-01 | 2018-01-05 |
| Pregnancy Outcome of Women Using Low Molecular Weight Heparin Before Frozen-thawed Embryo Transfer estrogen, Low Molecular Weight Heparin, hCG - Infertility | Phase 4 | Unknown | Nanfang Hospital, Southern Medical University | 342 | 2016-07-01 | 2017-04-19 |
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